Skeletal Scintigraphy for Routine Surveillance of M0 Prostatic Carcinoma

Author(s):  
S. St. C. Carter ◽  
A. J. W. Hilson ◽  
A. R. Constable ◽  
C. A. Lewis ◽  
P. J. R. Shah ◽  
...  
Author(s):  
W. Allen Shannon ◽  
José A. Serrano ◽  
Hannah L. Wasserkrug ◽  
Anna A. Serrano ◽  
Arnold M. Seligman

During the design and synthesis of new chemotherapeutic agents for prostatic carcinoma based on phosphorylated agents which might be enzyme-activated to cytotoxicity, phosphorylcholine, [(CH3)3+NCH2CH2OPO3Ca]Cl-, has been indicated to be a very specific substrate for prostatic acid phosphatase (PAP). This phenomenon has led to the development of specific histochemical and ultracytochemical methods for PAP using modifications of the Gomori lead method for acid phosphatase. Comparative histochemical results in prostate and kidney of the rat have been published earlier with phosphorylcholine (PC) and β-glycerophosphate (βGP). We now report the ultracytochemical results.Minced tissues were fixed in 3% glutaraldehyde-0.1 M phosphate buffered (pH 7.4) for 1.5 hr and rinsed overnight in several changes of 0.05 M phosphate buffer (pH 7.0) containing 7.5% sucrose. Tissues were incubated 30 min to 2 hr in Gomori acid phosphatase medium (2) containing 0.1 M substrate, either PC or βGP.


1976 ◽  
Vol 38 (6) ◽  
pp. 924-930 ◽  
Author(s):  
Hidekazu SHINODA ◽  
Kazuki MAEZIMA ◽  
Yasuko ISINO ◽  
Makoto HORI ◽  
Katsutaro NISHIMOTO

2007 ◽  
Author(s):  
Helen Clough ◽  
Jean Sanderson ◽  
Patrick Brown ◽  
Alexander Miller ◽  
Alasdair J. C. Cook

2019 ◽  
Vol 17 (4) ◽  
pp. 225-239 ◽  
Author(s):  
Lulu Zuo ◽  
Ke Peng ◽  
Yihong Hu ◽  
Qinggang Xu

AIDS is a globalized infectious disease. In 2014, UNAIDS launched a global project of “90-90-90” to end the HIV epidemic by 2030. The second and third 90 require 90% of HIV-1 infected individuals receiving antiretroviral therapy (ART) and durable virological suppression. However, wide use of ART will greatly increase the emergence and spreading of HIV drug resistance and current HIV drug resistance test (DRT) assays in China are seriously lagging behind, hindering to achieve virological suppression. Therefore, recommending an appropriate HIV DRT method is critical for HIV routine surveillance and prevention in China. In this review, we summarized the current existing HIV drug resistance genotypic testing methods around the world and discussed the advantages and disadvantages of these methods.


2018 ◽  
Vol 19 (2) ◽  
pp. 152
Author(s):  
Pupree Mutsuddy ◽  
Shamim MF Begum ◽  
Rahima Perveen ◽  
Mohammad Simoon Salekin

<p>Asymmetrical uptake of 99m Tc MDP (methylene diphosphonate) in skeletal scintigraphy in extremity may lead to confusion in the diagnosis of metastasis or complex regional pain syndrome. After the exclusion of possible contamination in this report a case was presented with asymmetrical uptake of MDP in the upper extremity from accidental intra-arterial injection.</p><p>Bangladesh J. Nuclear Med. 19(2): 152-154, July 2016</p>


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