Cytomorphometric and Morphological Analysis in Women with Trichomonas vaginalis Infection: Micronucleus Frequency in Exfoliated Cervical Epithelial Cells

2015 ◽  
Vol 59 (3) ◽  
pp. 258-264 ◽  
Author(s):  
Zehra Safi Oz ◽  
Banu Doğan Gun ◽  
Mustafa Ozkan Gun ◽  
Sukru Oguz Ozdamar
Keyword(s):  
Epithelial Cells ◽  
Trichomonas Vaginalis ◽  
Control Group ◽  
Study Group ◽  
Control Groups ◽  
The Mean ◽  
The Difference ◽  
Group 2 ◽  
And Control ◽  
Group 1

Objectives: The aim of this study was to explore the cytomorphometric and morphological effects of Trichomonas vaginalis in exfoliated epithelial cells. Study Design: Ninety-six Pap-stained cervical smears were divided into a study group and two control groups as follows: T. vaginalis cases, a first control group with inflammation, and a second control group without inflammation. Micronucleated, binucleated, karyorrhectic, karyolytic, and karyopyknotic cells and cells with perinuclear halos per 1,000 epithelial cells were counted. Nuclear and cellular areas were evaluated in 70 clearly defined cells in each smear using image analysis. Results: The frequencies of morphological parameters in the T. vaginalis cases were higher than the values of the two control groups, and the difference among groups was found to be significant (p < 0.05). The nuclear and cytoplasmic areas of epithelial cells were diminished in patients with trichomoniasis. The mean nucleus/cytoplasm ratio in T. vaginalis patients was higher than the value in the control groups, and the difference between the study group and control group 1 was significant. However, there was no statistically significant increase between the study group and control group 2. Conclusions:T. vaginalis exhibited significant changes in the cellular size and nuclear structure of the cells. The rising frequency of micronuclei, nuclear abnormalities, and changing nucleus/cytoplasm ratio may reflect genotoxic damage in trichomoniasis.

scholarly journals Tear Osmolarity Changes Following External and Trans-Canalicular Dacryocystorhinostomy in Primary Acquired Nasolacrimal Duct Obstruction

2021 ◽  
Author(s):  
Ceren Gurez ◽  
Şenay Aşık Nacaroğlu ◽  
Ahu Yılmaz
Keyword(s):  
Nasolacrimal Duct ◽  
Control Group ◽  
Control Groups ◽  
External Group ◽  
Healthy Control ◽  
External Dacryocystorhinostomy ◽  
The Mean ◽  
Group 2 ◽  
And Control ◽  
Group 1

Abstract Purpose: The aim of this study is to evaluate the tear osmolarity(TO) in patients with epiphora caused by primary acquired nasolacrimal-duct obstructions(PANDOs), before and one month after an external dacryocystorhinostomy(E-DCR) and trans-canalicular laser-assisted endoscopic dacryocystorhinostomy(TLA-DCR).Material-Methods: Twenty eyes of 21 patients(16 women, 5 men) who suffered from epiphora and, 20 healthy eyes of the same subjects were included in this study. External(Group 1) or laser-assisted(Group 2) DCR were applied to all patients with PANDO.Results: The mean age of the subjects was 60.09±8.46 in Group 1, 57.50±9.41 in Group 2 and, 55.13±9.38 in healthy control subjects. The mean period for complaints of epiphora was 1.9±0.7 years. Nasolacrimal duct irrigation was successful in all patients at the first-month visit after surgery. Group 1 had a mean TO of 284.16±12.43 mOsm/l and, Group 2 had 286.70±10.46 mOsm/l before DCR, and this increased to 295.75±5.86 mOsm/l and, 298.70±8.76 mOsm/l one month after DCR, respectively. Preoperative TO values in both groups were significant hypoosmolar compared with the control group (292.27±9.65 mOsm/l). No significant differences were detected between postoperative and control group TO values.Conclusion: We found no significant osmolarity changes between surgery and control groups.

scholarly journals True and Pseudo Cholinesterase levels in short and long-term of pesticides exposures

2020 ◽  
pp. 9-12
Author(s):  
Mohammed Abdul Rahman ◽  
Raghunatha Rao D ◽  
Vasantha L
Keyword(s):  
Whole Blood ◽  
Acute Poisoning ◽  
Mean Value ◽  
Serum Cholinesterase ◽  
Control Group ◽  
Study Group ◽  
Chronic Poisoning ◽  
The Mean ◽  
The Difference ◽  
And Control

The present study is aimed to study and analyze the true and pseudo Cholinesterase levels in the subjects exposed to pesticides during short term by intentional or accidental intake and long term exposure due to their occupation were studied at Department of Biochemistry, SVS medical college and hospital mahbubnagar district. Whole blood cholinesterase levels and Pseudo cholinesterase levels were estimated. 150 people were taken as controls who had no medical illness and a total number of 300 cases of pesticide poisoning were selected, aged between 20 to 55 years, which consist of 150 acute poisoning and 150 chronic poisoning subjects in Mahbubnagar district, were taken as case study, the detailed case history and the type of organophosphorus pesticide taken were recorded. Mean and standard deviation (S.D) of all variables were calculated and compared with those of controls. Statistical significance was assessed and P-value <0.05 were considered significant.           During acute poisoning the mean value of Whole blood cholinesterase/True cholinesterase (U / L) in acute poisoning cases on first day was 1.267± 0.612 on 3th day was 1.651±0.647, on 7th day was 2.221±0.684 and at the end of 6 months was 3.970±0.404.The difference between the study group and control group (4.0 ± 0.39) was found to be statistically significant in1st, 3rd, 7th day but not significant at the end of 6 months. The mean value of serum cholinesterase/pseudo cholinesterase (U/L) in acute poisoning cases on first day was 2213.05 ± 1749.81, on 3th day was 2862.3 ± 2025.6, on 7th day was 4008.4 ± 2355.9 and at the end of 6 months was 7708.34 ± 880.72.The difference between the study group and control group (7991.97 ± 1276.5) was found to be statistically significant in1st, 3rd, 7th day but not significant at the end of 6 months. During chronic poisoning (exposure) the mean value of Whole blood cholinesterase (U/L) in controls is 4.0 ± 0.39 as compared to 3.019 ± 0.848 in cases of chronic poisoning. The difference between the study group and control group was found to be statistically significant. The mean value of serum cholinesterase/pseudo cholinesterase (U/L) in controls was 7991.97 ± 1276.5 as compared to 6214 ± 1189 in cases of chronic poisoning. The difference between the study group and control group was found to be statistically significant.

scholarly journals Comparison of the results of percutaneous nephrolithotomy in different age groups

2018 ◽  
Vol 5 (12) ◽  
pp. 3888
Author(s):  
Ali Borekoglu ◽  
Ibrahim Atilla Aridogan ◽  
Mutlu Deger ◽  
Onur Karsli ◽  
Volkan Izol
Keyword(s):  
Blood Transfusion ◽  
Percutaneous Nephrolithotomy ◽  
Preoperative Evaluation ◽  
Control Group ◽  
Perioperative Bleeding ◽  
Significant Difference ◽  
The Mean ◽  
Group 2 ◽  
And Control ◽  
Group 1

Background: Evaluation of feasibility, safety and effectiveness of percutaneous nephrolithotomy (PCNL) in different age groups.Methods: Between July 1997-October 2012, 233 patients who were 65 years old and older were included in this study. These patients were divided into two age subgroups used in gerontology research. Group 1 was defined as patients 65-74 years old, Group 2 was older than 74 years old. Data from patient records, including demographic characteristics, preoperative evaluation, operative details, and complications were retrospectively analyzed and compared with control group data.Results: The mean age of 233 patients was 69.7±4.6 years. The mean operative times for Group 1, group 2 and the control group were 76.2±47.3mins, 92.9±47.6mins, 77±44mins, respectively and there was no statistically significant difference between groups 1 and 2 and the control group (p>0.05). Twenty-eight of the 233 patients (12%) needed blood transfusion due to perioperative bleeding. The transfusion rates of groups 1 and 2 were 11.3% and 16.7%, respectively. There was no statistically significant difference between the study groups and control group for blood transfusion rates (p>0.05). There was no statistically significant difference in complications between the study and control groups (p>0.05).Conclusions: In geriatric patients, stone-free rates, transfusion rates and other operation parameters are similar to younger populations when experienced surgeons perform PCNL. Despite comorbidities and decreased body reserve, PCNL can be performed without a significant increase in complications in different ages.

scholarly journals Effects of phenol, glycerin and acetic acid on the liver of guinea pigs

2007 ◽  
Vol 22 (6) ◽  
pp. 436-440 ◽  
Author(s):  
Rogério Saad-Hossne ◽  
William Saad Hossne ◽  
Mario Rubens Guimarães Montenegro
Keyword(s):  
Acetic Acid ◽  
Guinea Pigs ◽  
Hepatic Tissue ◽  
Control Group ◽  
Control Groups ◽  
Median Laparotomy ◽  
Group 2 ◽  
Tissue Recovery ◽  
And Control ◽  
Group 1

PURPOSE: To investigate the histolytic action of a solution composed of phenol, glycerin and acetic acid for irresectable hepatic metastasis. METHODS: Thirty-two (n=32) guinea pigs were randomly distributed into two groups of 16 animals. The animals in group 1 (experimental) and group 2 (control) were redistributed in two subgroups of eight animals each, according to the day of sacrifice (24 hours and four weeks after injection). All the animals were submitted to median laparotomy, which was followed by the injection of solution E and saline into the livers of subjects in both the experimental and control groups, respectively. The animals were evaluated for biochemical and anatomopathological (liver) alterations after 24 hours and four weeks of the experiment. RESULTS: It was observed that solution E produced necrosis limited to the injected area and that hepatic tissue recovery occurred after four weeks with the formation of a small necrosis area. No biochemical parameters were altered either in the experimental or in the control group. CONCLUSION: In view of the obtained results, the possibility of using the proposed solution can be considered in cases of irresectable metastasis.

Ultrasound-guided tip location of midline catheters

2020 ◽  
Vol 21 (5) ◽  
pp. 764-768
Author(s):  
Stefano Elli ◽  
Mauro Pittiruti ◽  
Valentina Pigozzo ◽  
Luigi Cannizzo ◽  
Luciano Giannini ◽  
...  
Keyword(s):  
Venous Thrombosis ◽  
Subclavian Vein ◽  
Control Group ◽  
Study Group ◽  
Axillary Vein ◽  
Ultrasound Guided ◽  
Catheter Tip ◽  
Group 2 ◽  
And Control ◽  
Group 1

Introduction: Midline catheters are widely used in clinical practice. Proper placement of midline catheter tip is usually assessed only by aspirating blood and flushing with normal saline without resistance. Purpose: To describe the ultrasound-guided tip location for midline catheters and its feasibility and to compare incidence of catheter-related venous thrombosis associated with or without ultrasound tip localization. Methods: The ultrasound-guided tip location is described step by step. Feasibility of the technique and incidence of catheter-related venous thrombosis were measured (study group) and compared with two historical groups: study group, 20-cm midline catheters inserted with ultrasound-guided tip location; group 1, 25-cm midline catheters inserted without ultrasound-guided tip location and group 2, 20-cm midline catheters inserted without ultrasound-guided tip location. Results: In the study group, ultrasound-guided tip location was easily feasible in 98.9% of patients. Incidence of catheter-related venous thrombosis was 2.42% in control group 1, 9% in control group 2 and 2.62% in the study group. Discussion: In the study group and control group 1, the tip was placed in the axillary vein, about 3 cm distal to the clavicle and in the subclavian vein. In control group 2, the tip was probably located at the transition between the axillary and the subclavian vein. It is possible that such position may have been associated with an increased incidence of catheter-related venous thrombosis. Conclusion: The ideal position of the tip of a midline catheter might be inside the axillary vein, about 3 cm distal to the axillary-subclavian transition or inside the subclavian vein. Ultrasound-guided tip location is safe, inexpensive, easy and potentially useful during midline catheters insertion.

scholarly journals Effectiveness of Solifenacin for Managing of Bladder Spasms in Patients With Urethroplasty

2017 ◽  
Vol 11 (5) ◽  
pp. 1580-1587 ◽  
Author(s):  
Xu Feng Peng ◽  
Xiang Guo Lv ◽  
Hong Xie ◽  
Ying Long Sa ◽  
Yue Min Xu ◽  
...  
Keyword(s):  
Term Therapy ◽  
Control Group ◽  
Study Group ◽  
Control Groups ◽  
Short Term ◽  
Suprapubic Cystostomy ◽  
Urine Extravasation ◽  
Vas Scores ◽  
The Mean ◽  
And Control

To evaluate the efficacy and safety of solifenacin in the treatment of bladder spasms after urethroplasty. Patients underwent urethroplasty were randomly assigned to the study group ( n = 165) and the control group ( n = 150). Patients in the study group were treated with solifenacin for 7 days. Patients in the control group were placebo. Each group was further divided into four subgroups: paracentetic suprapubic cystostomy subgroup, traditional suprapubic cystostomy subgroup, former suprapubic cystostomy subgroup, and urethral catheter subgroup. A visual analogue scale (VAS) was used to measure the severity of bladder spasms. The mean duration of spasms, the frequency of spasms, and the incidences of urine extravasation and radiating pain were recorded each day. There were no significant differences in the VAS scores and mean duration of bladder spasms between the study and control groups . However, there was a significantly lower VAS score in the patients taking solifenacin in the paracentetic suprapubic cystostomy subgroup ( p < .05). A similar tendency was noted in the mean duration of bladder spasms in this subgroup. In a comparison of the daily and nightly frequency of spasms within the four subgroups, a significant improvement was noted in the control group within 5 days. A similar difference was not noted within 6 days in the study group. The short-term therapy with solifenacin is an effective and safe method for decreasing the frequency of bladder spasms after urethroplasty. Patients undergoing paracentetic suprapubic cystostomy might be the only subset to benefit from this treatment.

scholarly journals Evaluation of coagulation parameters in patients with parathyroid adenoma

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Murat Alay ◽  
Berrak Mermit Ercek ◽  
Gulcin Miyase Sonmez ◽  
Aysegul Sakin ◽  
Rifki Ucler ◽  
...  
Keyword(s):  
Parathyroid Adenoma ◽  
Patient Group ◽  
Protein S ◽  
Control Group ◽  
Control Groups ◽  
Coagulation Parameters ◽  
Significant Difference ◽  
The Mean ◽  
The Difference ◽  
And Control

Abstract Parathyroid adenoma is responsible for 80–85% of cases of primary hyperparathyroidism. Increased fibrinogen levels in patients with adenoma may increase the risk of atherosclerosis and cardiovascular events. The aim of this study was to investigate the relationship between coagulation parameters and parathyroid adenoma. A prospective study included 28 female patients with parathyroid adenoma aged 40–88 years and 27 age-matched healthy controls. The coagulation parameters were assessed for each participant. The mean ages of the patient and control groups were 57.7 ± 10.9 and 53.3 ± 9.31 years, respectively. The mean level of protein S activity was 65.79 ± 13.78 in the patient group and 77.00 ± 15.72 in the control group, and the difference was statistically significant (p = 0.013). The mean fibrinogen levels of the patient and control groups were 338.78 ± 63.87 mg/dL and 304.30 ± 45.67 mg/dL, respectively, and a significant difference was found (p = 0.041). However, no significant difference was evident between the two groups with regard to the D-dimer (p = 0.238), aPTT (p = 0.645), INR (p = 0.406), protein C (p = 0.076), and AT-III (p = 0.180) levels. A positive correlation was observed between adenoma volume and fibrinogen in the patient group (r = 0.711, p = 0.001). The protein S levels were lower and the fibrinogen levels higher in the patients with parathyroid adenoma.

S215 – The Effects of Topical Halofuginon on Myringotomy in Rats

2008 ◽  
Vol 139 (2_suppl) ◽  
pp. P147-P147
Author(s):  
Hakan Cincik ◽  
Taner Ozdemir ◽  
Engin C ekin ◽  
Salim Dogru ◽  
Atila Gungor ◽  
...  
Keyword(s):  
Isotonic Saline ◽  
Healing Time ◽  
Control Group ◽  
Study Group ◽  
Control Groups ◽  
The Difference ◽  
Temporal Bones ◽  
And Control ◽  
Incision Healing

Objectives 1) To investigate the role of halofuginone hydrobromide on myringotomy incision healing time. 2) To investigate the role of halofuginone hydrobromide on formation of myringosclerosis. Methods 40 rats with normal eardrums were involved in this study to determine if topical halofuginone application had an impact on prolonging the time for healing of myringotomy incision and its histopathological consequences. The study group and control group consisted of 30 and 10 rats, respectively. A posterior incision 1 mm in diameter was made on randomly selected healty eardrums of the rats. After making incision in the study group, gelfoam soaked in halofuginone hydrobromide of 30 mg/dl was applied on the perforation, while gelfoam dipped in isotonic saline was introduced to perforation in the control group. On days 1, 3,7,10,14,18,21, 24, 27 and 30, otoendoscopic evaluation of eardrums under general anesthesia was conducted and perforations were screened. On control days, one randomly selected rat from each group was sacrified and temporal bones were dissected in order to evaluate the tympanic membranes histopathologically. Results The average times for patency of perforation in study and control groups were 21.43 and 7.50 days, respectively. The difference was found to be statistically significant (p<0.05). Conclusions Histopathological evaluation revealed that halofuginone seems to result in low hyalinization and fibrosis on eardrum compared to the control group.

scholarly journals Otoacoustic emissions in detection of pre-clinical noise induced cochlear damage in military personnel

2015 ◽  
Vol 1 (2) ◽  
pp. 58 ◽  
Author(s):  
Abhijeet Bhatia
Keyword(s):  
Hearing Loss ◽  
Military Personnel ◽  
Otoacoustic Emissions ◽  
Noise Exposure ◽  
Control Group ◽  
Study Group ◽  
Control Groups ◽  
Cochlear Damage ◽  
Group 2 ◽  
Group 1

<p class="abstract"><strong><span lang="EN-US">Background:</span></strong><span lang="EN-US"> Objective of current study to analyse the utility of TEOAEs and DPOAEs to detect cochlear damage due to chronic exposure to firearm noise in Indian military personnel at a preclinical stage. Military personnel are exposed to firearm noise and need to be assessed for cochlear damage periodically.</span></p><p class="abstract"><strong><span lang="EN-US">Methods:</span></strong><span lang="EN-US"> This cross sectional study was conducted from May 2004 to Apr 2005. Indian army soldiers and general civilian population were included in the study. The TEOAE and DPOAE parameters of two control groups (civilians, no noise exposure, no HL: control group 1; soldiers, noise exposed, hearing loss: Control group 2) were compared with the study group (soldiers, noise exposure, no hearing loss: Study group).</span></p><p class="abstract"><strong><span lang="EN-US">Results: </span></strong>TEOAE amplitudes of the study group varied significantly from those of both the control groups at almost all frequencies. Overall amplitude too followed a similar trend. However, although the DPOAE amplitude of the study group was less than that of control group 1, the difference was not significant. The DPOAE amplitude of study group varied significantly from control group 2.</p><p class="abstract"><strong><span lang="EN-US">Conclusions: </span></strong>TEOAEs proved to be useful to distinguish between green ears and ears chronically exposed to impulse noise with and without hearing loss. But DPOAEs proved to be useful in distinguishing only between normal hearing from hearing loss ears.</p>

scholarly journals Effects of Yalom Group therapy on the Resilience and Meaning in Life of the Nurses in Covid-19 Centers

2021 ◽  
pp. 209-214
Keyword(s):  
Group Therapy ◽  
Meaning In Life ◽  
Control Group ◽  
Life Questionnaire ◽  
Control Groups ◽  
Significance Level ◽  
Post Test ◽  
The Mean ◽  
The Difference ◽  
And Control

Background and Objective: This study aimed to analyze the effects of the Yalom group therapy on the resilience and meaning in life of the nurses fighting COVID-19. Materials and Methods: This quasi-intervention pre-test post-test research was conducted with a control group. Statistical population of this study included all the nurses of the hospitals of Hamedan who cared for the COVID-19 patients in 2020. According to the inclusion and exclusion criteria, 32 nurses were randomly selected and divided equally into the intervention and control groups. The intervention group was treated by the Yalom group therapy for 10 sessions. Evaluation tools were the Connor-Davidson (2003) Resilience Questionnaire and The Meaning in Life Questionnaire of Steger et al. which were completed by both groups at pre-test and post-test stages. The data were analyzed using the multivariate analysis of covariance and univariate analysis of variance in SPSS software (version 24). Results: The significance level of the difference between the mean scores of "meaning in life" was less than 0.05 (P<0.05). Hence, the difference between the means was significant and it can be said that the Yalom group therapy affects the meaning in life. According to the eta-squared value, the extend of this impact was about 64%. Moreover, the difference between the mean of the resilience scores of the intervention and control group was 58.94 and the significance level of this value was less than 0.05 (F [1 and 27] =58.937, P=0.001). Therefore, the difference between the means of the resilience scores of the intervention and control groups was significant with 95% confidence. It can be said that the Yalom group therapy had a significant impact on the resilience of the nurses. Conclusion: The results can be used to maintain and care for the mental health of nurses during severe disease epidemics, such as the Coronavirus epidemic.

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