scholarly journals True and Pseudo Cholinesterase levels in short and long-term of pesticides exposures

2020 ◽  
pp. 9-12
Author(s):  
Mohammed Abdul Rahman ◽  
Raghunatha Rao D ◽  
Vasantha L
Keyword(s):  
Whole Blood ◽  
Acute Poisoning ◽  
Mean Value ◽  
Serum Cholinesterase ◽  
Control Group ◽  
Study Group ◽  
Chronic Poisoning ◽  
The Mean ◽  
The Difference ◽  
And Control

The present study is aimed to study and analyze the true and pseudo Cholinesterase levels in the subjects exposed to pesticides during short term by intentional or accidental intake and long term exposure due to their occupation were studied at Department of Biochemistry, SVS medical college and hospital mahbubnagar district. Whole blood cholinesterase levels and Pseudo cholinesterase levels were estimated. 150 people were taken as controls who had no medical illness and a total number of 300 cases of pesticide poisoning were selected, aged between 20 to 55 years, which consist of 150 acute poisoning and 150 chronic poisoning subjects in Mahbubnagar district, were taken as case study, the detailed case history and the type of organophosphorus pesticide taken were recorded. Mean and standard deviation (S.D) of all variables were calculated and compared with those of controls. Statistical significance was assessed and P-value <0.05 were considered significant.           During acute poisoning the mean value of Whole blood cholinesterase/True cholinesterase (U / L) in acute poisoning cases on first day was 1.267± 0.612 on 3th day was 1.651±0.647, on 7th day was 2.221±0.684 and at the end of 6 months was 3.970±0.404.The difference between the study group and control group (4.0 ± 0.39) was found to be statistically significant in1st, 3rd, 7th day but not significant at the end of 6 months. The mean value of serum cholinesterase/pseudo cholinesterase (U/L) in acute poisoning cases on first day was 2213.05 ± 1749.81, on 3th day was 2862.3 ± 2025.6, on 7th day was 4008.4 ± 2355.9 and at the end of 6 months was 7708.34 ± 880.72.The difference between the study group and control group (7991.97 ± 1276.5) was found to be statistically significant in1st, 3rd, 7th day but not significant at the end of 6 months. During chronic poisoning (exposure) the mean value of Whole blood cholinesterase (U/L) in controls is 4.0 ± 0.39 as compared to 3.019 ± 0.848 in cases of chronic poisoning. The difference between the study group and control group was found to be statistically significant. The mean value of serum cholinesterase/pseudo cholinesterase (U/L) in controls was 7991.97 ± 1276.5 as compared to 6214 ± 1189 in cases of chronic poisoning. The difference between the study group and control group was found to be statistically significant.

Cytomorphometric and Morphological Analysis in Women with Trichomonas vaginalis Infection: Micronucleus Frequency in Exfoliated Cervical Epithelial Cells

2015 ◽  
Vol 59 (3) ◽  
pp. 258-264 ◽  
Author(s):  
Zehra Safi Oz ◽  
Banu Doğan Gun ◽  
Mustafa Ozkan Gun ◽  
Sukru Oguz Ozdamar
Keyword(s):  
Epithelial Cells ◽  
Trichomonas Vaginalis ◽  
Control Group ◽  
Study Group ◽  
Control Groups ◽  
The Mean ◽  
The Difference ◽  
Group 2 ◽  
And Control ◽  
Group 1

Objectives: The aim of this study was to explore the cytomorphometric and morphological effects of Trichomonas vaginalis in exfoliated epithelial cells. Study Design: Ninety-six Pap-stained cervical smears were divided into a study group and two control groups as follows: T. vaginalis cases, a first control group with inflammation, and a second control group without inflammation. Micronucleated, binucleated, karyorrhectic, karyolytic, and karyopyknotic cells and cells with perinuclear halos per 1,000 epithelial cells were counted. Nuclear and cellular areas were evaluated in 70 clearly defined cells in each smear using image analysis. Results: The frequencies of morphological parameters in the T. vaginalis cases were higher than the values of the two control groups, and the difference among groups was found to be significant (p < 0.05). The nuclear and cytoplasmic areas of epithelial cells were diminished in patients with trichomoniasis. The mean nucleus/cytoplasm ratio in T. vaginalis patients was higher than the value in the control groups, and the difference between the study group and control group 1 was significant. However, there was no statistically significant increase between the study group and control group 2. Conclusions:T. vaginalis exhibited significant changes in the cellular size and nuclear structure of the cells. The rising frequency of micronuclei, nuclear abnormalities, and changing nucleus/cytoplasm ratio may reflect genotoxic damage in trichomoniasis.

scholarly journals The Implementation of Flipped Learning in Squash Method Material in Microtechnique Course

BIOEDUSCIENCE ◽  
2020 ◽  
Vol 4 (2) ◽  
pp. 166-176
Author(s):  
Puspita Ratna Susilawati
Keyword(s):  
Learning Model ◽  
Mean Value ◽  
Student Understanding ◽  
Control Group ◽  
Flipped Learning ◽  
Control Group Design ◽  
Equivalent Control ◽  
The Mean ◽  
The Difference ◽  
And Control

Background: The implementation of flipped learning could be one of the solutions offered so that practicum that was limit by time could be carried out. This study aimed to determine the effect of implementing the flipped learning model on student understanding of the squash method material in microtechnique courses. Methods: This quasi study used a non-equivalent control group design. In the treatment group the flipped learning model was applied and an analysis of its effect on student understanding was carried out. The research data were obtained through the pretest and posttest. The pretest is used to evaluate the ability to remembering and understanding, while the posttest evaluates the ability to analyze, evaluate and create. The pretest and posttest value data were used to calculate the N-gain value, then the Mann-Whitney U test was performed to determine the difference between the two. Results: The increase in the mean value in the treatment class was higher than in the control class. The treatment class was 5.2, while the control class was 0.82. The percentage of students who showed a high and moderate N-gain score in the treatment class was 54.05%, while the control class was 40%. There was no difference between the N-gain value in the treatment and control classes. The flipped learning model's implementation did not affect student understanding but had been able to increase student understanding of the squash method material. Conclusions: The flipped learning model could be applied as a solution to practical problems constrained by time constraints.    

scholarly journals Epistaxis as a marker for severe acute respiratory syndrome coronavirus-2 status – a prospective study

2020 ◽  
Vol 134 (8) ◽  
pp. 717-720 ◽  
Author(s):  
MH Hussain ◽  
M Mair ◽  
P Rea
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Prospective Study ◽  
Control Group ◽  
Study Group ◽  
Chain Reaction ◽  
Polymerase Chain Reaction Testing ◽  
The Mean ◽  
Polymerase Chain ◽  
The Difference ◽  
A Prospective Study

AbstractObjectiveTo evaluate the prevalence of severe acute respiratory syndrome coronavirus-2 infection in patients presenting with epistaxis to a tertiary otolaryngology unit.MethodsA prospective study was conducted of 40 consecutive patients presenting with epistaxis referred to our tertiary otolaryngology unit. A group of 40 age-matched controls were also included. All patients underwent real-time reverse transcriptase polymerase chain reaction testing for severe acute respiratory syndrome coronavirus-2. Symptoms of fever, cough and anosmia were noted in the study group.ResultsThe mean age was 66.5 ± 22.4 years in the study group. There were 22 males (55 per cent) and 18 females (45 per cent). The mean age in the control group was 66.3 ± 22.4 years (p = 0.935). There were six positive cases for severe acute respiratory syndrome coronavirus-2 (15 per cent) in the epistaxis group and one case (2.5 per cent) in the control group. The difference was statistically significant (p = 0.05).ConclusionEpistaxis may represent a presenting symptom of severe acute respiratory syndrome coronavirus-2 infection. This may serve as a useful additional criterion for screening patients.

Increased Mean Platelet Volume in Patients With Aortic Stenosis

2010 ◽  
Vol 17 (6) ◽  
pp. E17-E20 ◽  
Author(s):  
Ercan Varol ◽  
Akif Arslan ◽  
Habil Yucel ◽  
Mehmet Ozaydin ◽  
Dogan Erdogan ◽  
...  
Keyword(s):  
Aortic Stenosis ◽  
Platelet Activation ◽  
Mean Platelet Volume ◽  
Matched Control ◽  
Control Group ◽  
Study Group ◽  
Platelet Volume ◽  
Echocardiographic Examination ◽  
The Mean ◽  
And Control

Background: Systemic thromboembolism is a serious complication in patients with aortic stenosis (AS). Previous studies have demonstrated that platelet activation occurs in patients with AS. The aim of this study was to assess the mean platelet volume (MPV), an indicator of platelet activation in patients with AS. Patients and Methods: The study group consisted of 43 patients with AS. An age-, gender-, and body mass index−matched control group consisted of 35 healthy volunteers. All patients and control participants underwent echocardiographic examination. We measured the serum MPV values in patients and control participants. Results: Mean platelet volume was significantly higher among patients with AS when compared with the control group (8.7 ± 1.0 vs 7.9 ± 0.9 fL, respectively; P = .001). Conclusion: We have shown that MPV was significantly elevated in patients with AS compared to control participant.

TNF-α and intPLA2 genes' polymorphism in anorexia nervosa

2004 ◽  
Vol 16 (6) ◽  
pp. 290-294 ◽  
Author(s):  
Agnieszka Slopien ◽  
Filip Rybakowski ◽  
Monika Dmitrzak-Weglarz ◽  
Piotr Czerski ◽  
Joanna Hauser ◽  
...  
Keyword(s):  
Anorexia Nervosa ◽  
Gene Polymorphism ◽  
Control Group ◽  
Study Group ◽  
Intron 1 ◽  
Tnf Α ◽  
The Mean ◽  
Polymerase Chain ◽  
And Control ◽  
Necrosis Factor

Objective:The aim of this study was the assessment of −308G/A tumor necrosis factor (TNF)-α gene polymorphism and intPLA2 gene polymorphism in patients with anorexia nervosa (AN) and healthy controls.Subjects:We studied 91 non-related patients with AN and 144 healthy women (blood donors and students). The mean age of women from study group was 18.22 years (SD ± 3.13 years) and from control group was 31.71 years (SD ± 8.22).Methods:Gene polymorphisms were studied with the use of polymerase chain reaction-restriction fragment length polymorphism method. TNF-α gene polymorphism consists of G/A substitution in −308 promoter region. IntPLA2 gene polymorphism is related to intron 1, in which restrictive region is found and recognized by BanI enzyme.Results:We did not obtain statistically significant differences in the frequency of genotypes and alleles of −308G/A TNF-α polymorphism between the study and control groups (genotypes: P = 0.106, alleles: P = 0.076). We did analogous analysis in the restrictive and bulimic subgroups. We did not observe statistically relevant differences in the frequency of genotypes (P = 0.700) and alleles (P = 0.305). We did not obtain statistically relevant difference in the frequency of genotypes and alleles of intPLA2 gene between the study group and controls (genotypes: P = 0.300, alleles: P = 0.331). We did analogous analysis in both subgroups of AN. We did not observe statistically relevant differences in the frequency of genotypes (P = 0.344) and alleles (P = 0.230).Conclusions:There was no statistically relevant trend for the association between TNF-α polymorphism and AN. We did not find association between studied polymorphism of intPLA2 gene and risk of AN.

scholarly journals EFFECT OF BRAIN EXERCISE AND BENSON RELAXATION THERAPY ON DEPRESSION LEVEL IN THE ELDERLY IN THE ELDERLY SOCIAL SERVICE UNIT

2018 ◽  
Vol 4 (2) ◽  
pp. 211-218
Author(s):  
Wulansari Wulansari ◽  
Ani Margawati ◽  
Rita Hadi W
Keyword(s):  
Social Service ◽  
The Elderly ◽  
Mean Value ◽  
Control Group ◽  
Relaxation Therapy ◽  
Service Unit ◽  
Significant Difference ◽  
Depression Level ◽  
The Mean ◽  
And Control

Background: Depression is one of the most common psychosocial problems in the elderly. The incidence of depression in the elderly is greater in the elderly living in the social service unit than the elderly in the community. Management of depression in the elderly should be more emphasized on interventions that focus on the individual needs of the biopsychosocial and spiritual aspects. Brain gym therapy and Benson relaxation are considered appropriate in decreasing depression.Objective: This study was to determine the effect of brain exercise and Benson relaxation on the level of depression in elderly in the elderly social service unit.Methods: This was a quasy experimental study with pretest posttest control group design. Fifty-six elderly included in this study, which 28 assigned in the experiment and control group. The depression level was assessed using Geriatric Depression Scale (GDS). Wilcoxon and Mann-Whitney test were used for data analyses.Results: The study showed that the mean GDS score in the experiment group before the intervention was 7.21, while the mean value of GDS in the control group was 6.64. The mean value of GDS in the experiment group after the intervention was 5.04 and the mean in control group was 6.18. There was a significant difference of GDS score between experiment and control group with p-value of 0.021 (<0.05).Conclusion: There was a significant effect of brain gymnastics and Benson relaxation therapy in reducing depression in elderly. brain gymnastic therapy and benson relaxation can be one of independent nursing interventions as an effort to improve care for elderly groups.

scholarly journals The Effects of Task-Based Language Teaching on Writing Achievement at a High School in Vietnam

2021 ◽  
Vol 04 (09) ◽  
Author(s):  
Dang Thi Thu Huong ◽  
Keyword(s):  
High School ◽  
Teaching Writing ◽  
Control Group ◽  
Writing Achievement ◽  
Significant Difference ◽  
Post Test ◽  
The Mean ◽  
The Difference ◽  
And Control ◽  
Experimental Group

The current study determines the effectiveness of using task-based language instructions in teaching writing at a high school in Thai Nguyen province. The participants consist of 92 grade 10 students from Bing Yen high school, Dinh Hoa district. The study employs a mix method research design (MMR) as the plan for the research. The results of the study reveals that the results of writing performance were reported at a low level (M=3.72). The results also confirmed that the intervention worked well for the experimental group. The mean score of the pre-test (the baseline for both groups) was M=3.72. The intervention focused on TBLT instructions. After first five weeks, the means of post-test1 were M=4.96 and M=3.83 for experimental group and control group respectively. There was a significant difference between the mean of pre-test and post-test1 for the experimental group (M=3.72 compared to M=4.96), while the control group showed a little improvement (M=3.72 compared to M=3.83) the difference was not significant. After another five weeks, the difference in the mean scores of the experimental group were far more than the mean scores of the control group, M=5.56 and M=4.45 respectively. By the end of the fifteenth week of the intervention, the mean of post-test 3 of the experimental group reached M=6.41, the mean for control group was M=5.54. The difference of the mean scores in the pre-test and post-test revealed a significant improvement in both groups. However, the experimental group showed a greater improvement, M=6.41 and M=5.54 respectively. It can infer that the uses of TBLT writing instruction improved writing achievement greatly.

scholarly journals Serum Periostin Level in Asthmatic Children with Exercise Induced Bronchospasm

2020 ◽  
pp. 53-67
Author(s):  
Reem M. Soliman ◽  
Mohamed B. Hamza ◽  
Rasha M. El-Shafiey ◽  
Hesham A. Elserogy ◽  
Nabil M El-Esawy
Keyword(s):  
Test Group ◽  
Mean Value ◽  
Control Group ◽  
Asthmatic Children ◽  
Group A ◽  
The Mean ◽  
Exercise Induced ◽  
Group B ◽  
And Control ◽  
Serum Periostin

Background: There are few biomarkers that can be easily accessed in clinical settings and may reflect refractory Th2-eosinophlic inflammation and remodeling of the asthmatic airways. Serum periostin may be one such biomarker to aid our understanding of the patho-bio-physiology of asthma and exercise induced asthma. The aim of the study is to explore the relationship between serum periostin level and exercise induced bronchoconstriction in asthmatic children. Materials and Methods: This cross-sectional study was carried out on (90) children both sexes aged from 6 to 15 years including, (60) children with bronchial asthma and (30) children were enrolled as control group in the period from January 2018 to January 2019. Patients were randomly classified into two groups: I) Patient group: divided into 2 groups according to standardized treadmill exercise challenge test: Group A: (30) asthmatic children with positive test. Group B: (30) asthmatic children with negative test. II-Control group: (30) children apparently healthy with no personal or family history of asthma. All children were subjected to the following Investigations: Chest x-ray, pulmonary functions tests (FEV1 & PEFR) except controls, Laboratory investigations as CBC and Serum periostin level. Results: The mean values of both the percentage of PEFR and FEV1 after exercise in group A were significantly lower than those in group B and the percentage of PEFR and FEV1 after exercise in each group were significantly lower than the percentage before exercise in the same group. The mean value of eosinophilic count in group A was significantly higher than (group B and control group) and the mean value of eosinophilic count in group B was significantly higher than control group. The mean value of serum level of periostin in group A was significantly higher than (group B and control group), however, there was no significant difference between group B and control group as regard to serum level of periostin. Chest tightness, cough and wheezes after exercise and eosinophilic count in patients with high serum periostin level were significantly higher than patients with low serum periostin level, and both PEFR and FEV1 after exercise in patients with high serum periostin level were significantly lower than patients with low serum periostin level. Also the normal serum periostin levels vary among different age groups. Conclusion: Serum periostin level can be considered as a useful biomarker for diagnosis of Exercise induced bronchospasm (EIB) in asthmatic children especially when lung function test cannot be done However, cautious is required in evaluating serum periostin levels in children because it varies with age.

scholarly journals Effect of Foetal Movement Counting on Prenatal Attachment and Maternal Worries among Primigravidas- A Longitudinal Study

2021 ◽  
Author(s):  
Jignya Vinodbhai Asari ◽  
Anjali Pushkar Tiwari
Keyword(s):  
Longitudinal Study ◽  
Control Group ◽  
P Value ◽  
Study Group ◽  
Prenatal Attachment ◽  
Study Results ◽  
Significant Difference ◽  
The Mean ◽  
Foetal Movement ◽  
And Control

Introduction: Pregnant woman experience various physical, emotional, and hormonal changes that may cause anxiety. The anxiety and worries can be decreased by sharing information about the developing child, like foetal body movement. Aim: To assess effect of Foetal Movement Counting (FMC) on prenatal attachment and maternal worries among primigravida mothers. Materials and Methods: A longitudinal study was carried out among primigravida mothers of selected Hospitals of Central Gujarat using proforma of Cranley’s maternal foetal attachment scale and Cambridge worry scale. The study was conducted from March 2019 to July 2020. Eighty participants were recruited by convenient sampling 40 in each study group and control group. The study group were provided with foetal movement chart and the participants were asked to record foetal movements for seven consecutive days, twice a day for 20 minutes. Post assessment of prenatal attachment and maternal worries was done using tools of data collection for both study and control group. Chi- square test was used to test the significance (p-value <0.05). Results: The study results revealed that in study group mean score for prenatal attachment was 79.43 at the start and improved to 101.25 (p-value <0.001) after seven days of FMC. In control group, the mean score for prenatal attachment did not show significant difference pre-test and post-test (74.20 vs 74.85, p-value=0.077). In study group, the mean Cambridge worry scale score was 36.55 which came down to 20.28 (p-value <0.001) after seven days, while in control group it was 41.38 at the beginning and 41.30 after seven days (p-value=0.998). Conclusion: Foetal Movement Counting was found to improve maternal foetal attachment and reduce maternal worries. FMC can be routinely and effectively promoted among the pregnant population to help them achieve a positive pregnancy experience and outcome.

scholarly journals The Relationship Between Intraabdominal Hypertension and Preeclampsia

2016 ◽  
pp. 5
Author(s):  
Mesut A. Ünsal ◽  
Ülkü İnce ◽  
Sevil Cengiz ◽  
S. Caner Karahan ◽  
Turhan Aran
Keyword(s):  
Statistical Significance ◽  
Intraabdominal Pressure ◽  
Control Group ◽  
Abdominal Pressure ◽  
Study Group ◽  
Abdominal Hypertension ◽  
Intraabdominal Hypertension ◽  
The Mean ◽  
And Control ◽  
The Relationship

<p><strong>OBJECTIVE:</strong> We aimed to measure abdominal pressure and placental levels of malondialdehyde in patients with preeclampsia and investigate the relationship between intraabdominal pressure and clinical features of preeclampsia.<br /><strong>STUDY DESIGN:</strong> Study was conducted at a tertiary referral clinic. Study group consisted of patients with preeclampsia and control group consisted of normotensive pregnant women. Both placental malondialdehyde and intraabdominal pressure levels were studied in all patients. Intraabdominal pressure was assessed indirectly via a Foley bladder catheter both antepartum and postpartum period. Statistical comparisons among groups were made using the Mann-Whitney U test, independent T test and Chi-square test. Statistical significance was set as p&lt;0.05.<br /><strong>RESULTS:</strong> Study and control group consisted of 35 pregnant patients. The mean patients’ age, gravidity, parity, weight and BMI were not different between study and control groups. In the study group, Caesarean, preterm delivery and abdominal hypertension rate were significantly higher whereas the mean neonatal birth weight was lower. The mean antepartum and postpartum intraabdominal pressure levels were significantly higher in study group. The mean intraabdominal pressure was highest in patients with oliguria (19.8±1.8 cmH2O). Abdominal hypertension was detected in 30 (86%) patients in study group and in 3 (9%) patients in control group. The mean placental malondialdehyde level was significantly higher in patients with intraabdominal hypertension.<br /><strong>CONCLUSION:</strong> Abdominal hypertension rate is very high in patients with preeclampsia. Abdominal hypertension may have an additional role in preeclampsia.</p>

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