Is a Central Venous Catheter Necessary for the Perioperative Management of Esophagectomy? A Prospective Randomized Pilot Study Comparing Two Different Perioperative Regimens

2016 ◽  
Vol 33 (6) ◽  
pp. 478-487 ◽  
Author(s):  
Katsumasa Saito ◽  
Yasuaki Nakajima ◽  
Kenro Kawada ◽  
Yutaka Tokairin ◽  
Tatsuyuki Kawano
Ultrasound ◽  
2021 ◽  
pp. 1742271X2110517
Author(s):  
Mohd Jazman Che Rahim ◽  
Shaik Farid Abdull Wahab ◽  
Mohd Hashairi Fauzi ◽  
Chandran Nadarajan ◽  
Siti Azrin Ab Hamid

Background Contrast-enhanced ultrasonography (CEUS) using saline was studied to detect supradiaphragmatic central venous catheter malposition. Commonly used echocardiographic views are apical 4-chamber (A4c) and subcostal views. However, this standard method is not feasible in certain situations. We explored the feasibility of the right ventricle inflow parasternal long axis (RVI-PLAX) echocardiographic view and dextrose 50% (D50%) contrast solution for detecting supradiaphragmatic central venous catheter malposition. Method This pilot study screened 60 patients who underwent ultrasound-guided supradiaphragmatic central venous catheter insertion. We compared the investigators' guidewire's J-tip detection, D50% rapid atrial swirl sign (RASS) findings on the RVI-PLAX view and the central venous catheter tip on chest radiograph. We also compared the mean capillary blood sugar level before and after the 5 ml D50% flush. Results No guidewire J-tips were detected from the RVI-PLAX view. The first and second investigators’ diagnosis of central venous catheter malposition detected on RVI-PLAX CEUS achieved an almost perfect agreement (κ = 1.0 (95% confidence interval (CI): 0.90 to 1.0), p < .0001). The RVI-PLAX CEUS was not able to detect two central venous catheter malpositions (one atrial malposition and one left brachiocephalic vein venous catheter malposition). The capillary blood sugar was significantly elevated (8.96 mmol/L vs. 9.75 mmol/L) after D50% flush ( p < 0.005) with no complications reported within 30 minutes after the D50% flush. Conclusion RVI-PLAX view should not be used for guidewire detection. CEUS using D50% and RVI-PLAX view are potentially useful tools in detecting central venous catheter malposition. Further studies comparing them with conventional methods are needed.


BMJ ◽  
1996 ◽  
Vol 313 (7071) ◽  
pp. 1528-1529 ◽  
Author(s):  
M. J Tighe ◽  
P. Kite ◽  
W. N Fawley ◽  
D. Thomas ◽  
M. J McMahon

2021 ◽  
pp. 106002802110533
Author(s):  
Lara M. Groetzinger ◽  
Julia Williams ◽  
Susan Svec ◽  
Michael P. Donahoe ◽  
Phillip E. Lamberty ◽  
...  

Background: Reducing central venous catheter (CVC) utilization can reduce complications in the intensive care unit (ICU). While norepinephrine (NE) is traditionally administered via a CVC, lower concentrations may be safely administered via peripheral intravenous (PIV) lines. Objective: We aimed to describe the implementation of a pilot protocol utilizing PIVs to administer a low-dose and lower-concentration NE, review the number of CVCs avoided, and evaluate any adverse events. Methods: In a quaternary medical intensive care unit (MICU), from March 1, 2019, to February 29, 2020, we reviewed charts for CVC placement and adverse events from the pNE infusion. We also measured unit-level CVC utilization in all MICU patients and assessed the change in utilization associated with the peripheral norepinephrine (pNE) protocol. Results: Over a 1-year period, 87 patients received a pNE infusion. Overall, 44 patients (51%) never required CVC placement during their MICU stay. Three patients (3%) experienced adverse events, none of which were documented as serious and or required antidote for treatment. Implementation of the protocol was associated with a decrease in the number of patients at the unit level who received CVCs, even if they did not receive pNE. Conclusion and Relevance: In this small pilot study, we pragmatically demonstrated that pNE is safe and may reduce the need for CVC placement. This information can be used to aid in pNE protocol development and implementation at other institutions, but further research should be done to confirm the safety of routine use of pNE in clinical practice.


2015 ◽  
Vol 31 (5) ◽  
pp. 827-832 ◽  
Author(s):  
Fabio Paglialonga ◽  
Andrea Artoni ◽  
Simon Braham ◽  
Silvia Consolo ◽  
Alberto Giannini ◽  
...  

PLoS ONE ◽  
2015 ◽  
Vol 10 (8) ◽  
pp. e0135904 ◽  
Author(s):  
Joshua Wolf ◽  
Li Tang ◽  
Jeffrey E. Rubnitz ◽  
Rachel C. Brennan ◽  
David R. Shook ◽  
...  

2005 ◽  
Vol 6 (4) ◽  
pp. 177-181 ◽  
Author(s):  
K. Laliberte ◽  
S. Jerat ◽  
K. Tenneson ◽  
M. Wade ◽  
D. Zaccardelli

Purpose Two animal studies were conducted to determine the feasibility of infusing treprostinil via a central venous catheter at an infusion rate of 0.1 mL/hour. Currently treprostinil is administered intravenously at infusion rates of approximately 1.0 to 2.0 mL/hour to patients with pulmonary arterial hypertension, which reflects standard clinical practice to ensure line patency with continuous intravenous administration via a central venous catheter. Methods In a pilot study three male beagle dogs were administered 50 ng/kg/min of treprostinil continuously at an infusion rate of 0.1 mL/hr via the MiniMed 407C infusion pump for 21 days. In a definitive study, six male beagle dogs were administered 50 ng/kg/min of treprostinil continuously at an infusion rate of 0.1 mL/hr via the MiniMed 407C infusion pump for 60 days. In both studies “no delivery” pump alarms were documented throughout the study in addition to pharmacokinetic data at specified time points. Results There were no documented occlusions in the 21-day pilot study. In the 60-day study one animal had a documented catheter occlusion after 16 days of therapy. Following re-implantation with a new catheter this animal did not have any additional occlusions for 40 days. No other animals in this study had any significant problems. In both studies, pharmacokinetic data were similar to that observed in previous animal studies evaluating treprostinil administration at the same dose and at higher infusion rates. Conclusion These animal data support the evaluation of administering treprostinil at a low infusion rate via the MiniMed 407C infusion pump in patients with pulmonary arterial hypertension.


Sign in / Sign up

Export Citation Format

Share Document