scholarly journals Granulomatous Mastitis: A Rare Cause of Male Breast Lump

2016 ◽  
Vol 9 (2) ◽  
pp. 516-519 ◽  
Author(s):  
Abdel Rahman A. Al Manasra ◽  
Mohammad F. Al-Hurani
Keyword(s):  
Breast Tissue ◽  
Nipple Discharge ◽  
Surgical Excision ◽  
Male Breast ◽  
Granulomatous Mastitis ◽  
Idiopathic Granulomatous Mastitis ◽  
Radiologic Findings ◽  
Female Breast ◽  
The Right ◽  
Histopathologic Findings

Background: Mastitis is a common benign disorder of the female breast. It is frequently associated with tenderness, swelling and nipple discharge. We are describing an extremely rare case of an idiopathic granulomatous mastitis in the male breast. Only 1 previous case was reported. Case Report: A 29-year-old male patient presented with a hard, painless lump in the right breast of 2 weeks duration. The patient underwent surgical excision with margin. The histopathologic findings were consistent with granulomatous mastitis. The case was reported as idiopathic granulomatous mastitis after exclusion of all known causes of the disease. Conclusion: Granulomatous mastitis is rare in females and extremely rare in male breast tissue. Since this disease mimics breast cancer in its clinical picture and radiologic findings are usually not conclusive, surgical excision is recommended in all cases.

scholarly journals Out Come of Wide Local Excision with and without Corticosteroid Therapy in Management of Idiopathic Granulomatous Mastitis

2021 ◽  
Vol 107 (1_suppl) ◽  
pp. 13-13
Author(s):  
R Amira Maher ◽  
Ahmed Gamal Eldin Osman ◽  
K Fahmy ◽  
Shinamwi M ◽  
Osama Al Atarash
Keyword(s):  
Recurrence Rate ◽  
Corticosteroid Therapy ◽  
Surgical Excision ◽  
Cosmetic Outcome ◽  
Systemic Steroid ◽  
Granulomatous Mastitis ◽  
Idiopathic Granulomatous Mastitis ◽  
Palpable Mass ◽  
Group A ◽  
Group B

Introduction: Idiopathic granulomatous mastitis is a rare benign breast disease. Initial reports from hospitals in Egypt from Departments of Pathology at Cancer Institutes of Cairo, Tanta and Mansoura Universities; indicate that the disease is not as rare as that in the developed countries. It often mimics breast carcinoma both clinically and radiologically. Histological examination is the gold standard for diagnosis. Management of Idiopathic granulomatous mastitis is still debatable. In our study, we aimed to evaluate the addition of corticosteroid therapy to surgical excision in management of idiopathic granulomatous mastitis. Patients and Methods: This is a comparative study was conducted at Ain-Shams University Hospital’s breast clinic on patients with idiopathic granulomatous mastitis from to August 2015 till September 2018. Thirty patients were divided into 2 groups. Group (A) includes patients who underwent surgical management only. Group (B) includes patients who received corticosteroid therapy according to the severity of the cases then surgical Excision was done for the residual lesion. Follow up of all cases up to 1-2 years was done to document the recurrence rate and compare the cosmetic outcome of both groups. Informed consent was obtained from all patients included in the study. Results: The mean age of the affected women was 38.80 and 33.13 in group (A) and group (B), respectively and it wasn’t statistically different (p value = 0.099). The most common presenting symptom was a palpable mass in the breast (66.7% and 93.3%) in group (A) and group (B) respectively. Recurrence rate was higher in group (A) (40%) with no recurrence documented in group (B) however 2 cases were omitted from the study due to steroid noncompliance and complications. Cosmetic outcome was excellent in 76.9% of group (B) and good in 53.3% of group (A). Conclusion: Systemic steroid therapy with surgical resection is the recommended as first-line treatment strategy for IGM as it shows less recurrence rate and surgical scarring. Increased awareness of IGM will increase their understanding and improve their management.

scholarly journals Idiopathic granulomatous mastitis: challenges of treatment in iranian women

BMC Surgery ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Leyla Shojaee ◽  
Nasrin Rahmani ◽  
Siavash Moradi ◽  
Asieh Motamedi ◽  
Gholamali Godazandeh
Keyword(s):  
Recurrence Rate ◽  
Low Dose ◽  
Unknown Origin ◽  
Surgical Excision ◽  
Chronic Inflammatory Disease ◽  
High Dose ◽  
Granulomatous Mastitis ◽  
Idiopathic Granulomatous Mastitis ◽  
Results Of Treatment ◽  
Information Treatment

Abstract Background and objective As a chronic inflammatory disease of an unknown origin, the treatment of granulomatous mastitis has always been controversial. According to some researchers, surgical treatment and certain medications, especially steroids, are more effective in treating the disease. This study aimed at evaluating the results of treatment in a group of patients with granulomatous mastitis. Materials and methods This longitudinal cohort study evaluated the treatment outcomes of 87 patients with pathology-confirmed granulomatous mastitis referred to the surgical clinic of Central Hospital in Sari, Iran. Demographic, clinical, and pathological information, treatment methods and results, and the recurrence rate were analyzed. Findings A total of 87 female patients with granulomatous mastitis aged 22–52 years with a mean age of 34 years were evaluated. All patients had palpable masses; the breast masses were painful in 48.3% of patients, and 55.2% of patients suffered from erythema and inflammation, and8% had fistulas and ulcers at the inflammation site. The patients were followed-up for an average duration of 26 months (8–48 months) after treatment and recovery. The overall recurrence rate was 24.1%, and the recurrence rate was 29.4% in patients underwent surgery, 34.8% in patients received high-dose prednisolone, and 17% in those received low-dose prednisolone together with drainage (p < 0.001). Conclusions According to the results, the low-dose prednisolone plus drainage was more effective with a lower recurrence rate than only surgical excision or high-dose prednisolone. In fact, the use of minimally invasive methods such as drainage plus low-dose steroids is a more effective method with fewer side effects than the other two methods.

Breast Mass with Bloody Discharge: A Case of Idiopathic Granulomatous Mastitis

2022 ◽  
Vol 7 (01) ◽  
pp. 58-61
Author(s):  
Lamees AlSulaim
Keyword(s):  
Breast Cancer ◽  
Advanced Breast Cancer ◽  
Nipple Discharge ◽  
Advanced Breast ◽  
Breast Mass ◽  
Breast Diseases ◽  
Granulomatous Mastitis ◽  
Idiopathic Granulomatous Mastitis ◽  
Skin Changes ◽  
Breast Condition

One of the rare identity of breast diseases is Idiopathic Granulomatous Mastitis (IGM), a chronic inflammatory breast condition that can mimic advanced breast cancer. The case came with nipple discharge and mass with skin changes, which was definitively diagnosed following core-cut biopsy of the mastitis group idiopathic granulomatous.

Idiopathic Granulomatous Mastitis in the Male Breast

2005 ◽  
Vol 11 (1) ◽  
pp. 73-73 ◽  
Author(s):  
K. Marcus Reddy ◽  
Carl E. R. Meyer ◽  
Amir Nakdjevani ◽  
Sunita Shrotria
Keyword(s):  
Male Breast ◽  
Granulomatous Mastitis ◽  
Idiopathic Granulomatous Mastitis

Mass in Male (Gynecomastia, Cancer)

2018 ◽  
Author(s):  
Eric Foo ◽  
Bonnie N. Joe
Keyword(s):  
Breast Cancer ◽  
Breast Tissue ◽  
Nipple Discharge ◽  
Male Breast ◽  
Differential Diagnoses ◽  
Benign Condition ◽  
Imaging Protocols ◽  
Management Recommendations

Gynecomastia is a benign condition manifesting as enlarged breasts in men and boys. This increased breast tissue is caused by excess fibroglandular deposits and is caused by hormonal imbalances, commonly due to estrogen excess or from various drugs, such as spironolactone, ketoconazole, cimetidine, ranitidine, and specific HIV therapies. Patients generally present with bilateral subareolar enlarged breasts (however, unilateral gynecomastia also occurs), which commonly exhibit tenderness on palpation, swelling, palpable lumps, or nipple discharge. This chapter reviews the important imaging protocols, pitfalls, differential diagnoses, radiology–pathology correlation, and management recommendations for gynecomastia and cancer of the male breast. Topics discussed include gynecomastia, breast cancer, pseudogynecomastia, hypogonadism, and lymphangioma.

A very rare cause of male breast lump: Idiopathic granulomatous mastitis

2019 ◽  
Vol 26 (4) ◽  
pp. 778-779
Author(s):  
Funda Dinç Elibol ◽  
Cenk Elibol ◽  
Leyla Tekin ◽  
Cem Dönmez
Keyword(s):  
Male Breast ◽  
Granulomatous Mastitis ◽  
Breast Lump ◽  
Idiopathic Granulomatous Mastitis

scholarly journals Presence of Luteinizing Hormone/Human Chorionic Gonadotropin Receptors in Male Breast Tissues

2004 ◽  
Vol 89 (8) ◽  
pp. 4119-4123 ◽  
Author(s):  
Harold E. Carlson ◽  
Philip Kane ◽  
Z. M. Lei ◽  
X. Li ◽  
C. V. Rao
Keyword(s):  
Chorionic Gonadotropin ◽  
Human Chorionic Gonadotropin ◽  
Breast Tissue ◽  
Male Breast ◽  
Normal Male ◽  
Receptor Mrna ◽  
Female Breast ◽  
Breast Tissues ◽  
Hcg Receptor

Receptors for LH/human chorionic gonadotropin (hCG) have been found in a variety of nongonadal tissues including the female breast. Using in situ hybridization and immunohistochemistry, we demonstrated the presence of LH/hCG receptor mRNA and protein in normal male breast tissue obtained at autopsy (n = 4) and archival samples of benign gynecomastia (n = 14) and male breast carcinoma (n = 5). Although the function of these receptors remains to be determined, the findings suggest the possibility that LH and hCG may play a role in the pathogenesis of male breast disorders.

scholarly journals Imaging features of idiopathic granulomatous mastitis – Case report

2016 ◽  
Vol 62 (4) ◽  
pp. 303-306
Author(s):  
Luciana Graziano ◽  
Almir Galvão Vieira Bitencourt ◽  
Caroline Baptista da Silva ◽  
Camila Souza Guatelli ◽  
Juliana Alves Souza ◽  
...  
Keyword(s):  
Case Report ◽  
Nipple Discharge ◽  
Unknown Etiology ◽  
Lactation Period ◽  
Imaging Features ◽  
Granulomatous Mastitis ◽  
Resonance Imaging ◽  
Idiopathic Granulomatous Mastitis ◽  
Bilateral Involvement ◽  
Magnetic Resonance Imaging Mri

Summary Idiopathic granulomatous mastitis is a rare disorder of unknown etiology. This disease occurs mostly in young women and often after the lactation period. Women usually present with a fixed, painful mass, sparing the retroareolar region, associated with skin thickening and possible ulceration that mimics carcinoma. Nipple discharge can be present and bilateral involvement may occur in up to 25% of cases. In this case report, we present a typical case of histologically confirmed idiopathic granulomatous mastitis, highlighting the imaging findings, including magnetic resonance imaging (MRI), which may favor this diagnosis and enable better clinical management of these patients.

scholarly journals Radiologic findings of idiopathic granulomatous mastitis

2015 ◽  
Vol 17 (1) ◽  
pp. 39 ◽  
Author(s):  
Seyma Yildiz ◽  
Ayse Aralasmak ◽  
Huseyin Kadioglu ◽  
Huseyin Toprak ◽  
Huseyin Yetis ◽  
...  
Keyword(s):  
Time Signal ◽  
Histopathological Diagnosis ◽  
Granulomatous Mastitis ◽  
Radiological Findings ◽  
Idiopathic Granulomatous Mastitis ◽  
Radiologic Findings ◽  
Irregular Margin ◽  
Number Of Patients ◽  
Hypoechoic Mass ◽  
T2 Hyperintensity

Aim: To describe the radiological findings of idiopathic granulomatous mastitis (IGM). Material and methods: Radio- logic findings of 30 women with histopathological diagnosis of IGM were retrospectively evaluated. All had breast feeding history. All the patients had ultrasonography (US), with 12 of them having additional Doppler US. Of 30 patients, 11 had mam- mography (MG) and 5 MRI. Results: US showed multiple irregular hypoechoic masses and collection areas with tubular con- nections in 25 of 30. The collection area with low-level internal echoes but without tubular connections, suggesting an abscess were seen in 2 of 30 (6.6%); a hypoechoic mass with an indistinct border in 2 of 30 (6.6%); multiple milimetric hypoechoic nodular masses in 1 of 30 (3.3%). On MG, normal findings were noted in 5 (45.4%); focal asymmetric density in 4 (36.4%), parenchymal distortion in 1 (9%) and diffuse asymmetric opacity with trabecular thickening in 1 (9%) of 30 patients. On MRI, segmental T2 hyperintensity with contrast-enhancement on T1 were seen in 4 of 5 (80%). An enhancing T2 hypointense mass with irregular margin was present in 1 of 5 (20%). Time-signal intensity curve of lesions showed slow enhancement in 1 and moderate in 4 of 5 patients. Conclusions: In IGM, MG findings were nonspecific. In US, multiple irregular hypoechoic masses and collections with tubular connections with fingerlike aspects, and fistulae formation to the skin in patients with breastfeed- ing history suggested IGM rather than carcinoma. Due to the limited number of patients, no conclusion was reached regarding MRI of IGM.

Treatment Modality of Idiopathic Granulomatous Mastitis with Surgery Alone or in Combination with Steroid

2021 ◽  
Vol 7 (1) ◽  
pp. 924-926
Author(s):  
Nilufar Shabnam ◽  
Md Iqbal Mahmud Choudhury ◽  
Tazin Ahsan
Keyword(s):  
Wide Spectrum ◽  
Surgical Excision ◽  
Disease Diagnosis ◽  
Chronic Inflammatory Disease ◽  
Fistula Formation ◽  
Controlled Clinical Trial ◽  
Granulomatous Mastitis ◽  
Inflammatory Mass ◽  
Idiopathic Granulomatous Mastitis ◽  
Therapeutic Modalities

Background: Idiopathic Granulomatous Mastitis (IGM) is a rare chronic inflammatory disease. Diagnosis and treatment is still a challenge because of obscure etiology and rareness. Owing to wide spectrum of IGM it is difficult to standardize and optimize the treatment. The aim of our study was to evaluate the outcome of surgical excision or in combination with steroid in treating IGM. Methodology: A randomized controlled clinical trial was done in BIRDEM (Bangladesh Institute of Research and Rehabilitation of Diabetic, Endocrine and Metabolic Disorder) Hospital, Dhaka, Bangladesh from July’2008 to June’2018. Overall 82 patients met the inclusion criteria. We analyzed therapeutic modalities and compared the patients’ outcomes based on treatment. Results: All patients underwent wide excision with clear margin under general anesthesia. Post operatively steroid was given in 41 patients. Duration of steroid therapy was 6 months after surgery. We have seen that recovery time was short in steroid group (Gr-II) average 167.07 days in compared without steroid (Gr l) average 253.28 days. Patients who underwent surgery only (GR-I) about 49.90% patients experienced recurrence (e.g. fistula formation and inflammatory mass etc.) On the other hand, 12.1% patients developed recurrences that were treated with steroid following surgery (Gr-II). Conclusion: Surgery with steroid is more effective in treatment of idiopathic granulomatous mastitis than surgery alone. Bioresearch Commu. 7(1): 924-926, 2021 (January)

Sign in / Sign up

Export Citation Format

Share Document