scholarly journals Synchronous and Metachronous Colon Cancers in Patients with Gastric Cancer: Report of 2 Cases

2016 ◽  
Vol 9 (3) ◽  
pp. 752-759
Author(s):  
Byoung Jo Suh
Keyword(s):  
Gastric Cancer ◽  
Anal Verge ◽  
Cancer Case ◽  
Adenocarcinoma In Situ ◽  
Colon Cancers ◽  
Laparoscopically Assisted Distal Gastrectomy ◽  
Well Differentiated ◽  
Pathological Report

Colorectal cancer is the most common synchronous or metachronous cancer in patients with gastric cancer. I report two cases of synchronous and metachronous colon cancer with gastric cancer. Case 1: A 70-year-old man was admitted to our hospital for the treatment of gastric cancer, which had been diagnosed during esophagogastroduodenoscopy (EGD) screening. The recommended preoperative testing was colonofiberscopy (CFS). The CFS revealed a 3-cm ulcerofungating mass, located 20 cm from the anal verge. The pathological report showed a well-differentiated adenocarcinoma. Consequently, we performed radical total gastrectomy and low anterior resection simultaneously. There was no recurrence during the 40-month follow-up of this individual on an out-patient basis. Case 2: A 71-year-old man who was treated with laparoscopically assisted distal gastrectomy (LADG) due to early gastric cancer underwent regular follow-up examination with EGD and abdominopelvic computed tomography. A CFS performed 5 years after the LADG revealed a polypoid mass in the sigmoid colon. The pathological report showed a villous adenoma with adenocarcinoma in situ. The patient underwent a colonofiberscopic mucosectomy. At 36 months after the endoscopic mucosectomy, the patient remained free of recurrence.

scholarly journals Loop Electrosurgical Excision Procedure in Cervical Intraepithelial Neoplasia

2016 ◽  
Vol 11 (1) ◽  
pp. 58-61
Author(s):  
Rima Maharjan ◽  
BK Thapa ◽  
Neershobha Chitrakar ◽  
Jitendra Pariyar ◽  
Isha Shrestha ◽  
...  
Keyword(s):  
Squamous Cell ◽  
Simple Procedure ◽  
Pap Test ◽  
Intraepithelial Neoplasia ◽  
Final Diagnosis ◽  
Invasive Squamous Cell Carcinoma ◽  
Adenocarcinoma In Situ ◽  
Cervical Lesions

Aims: To evaluate the treatment outcome and acceptance of LEEP in precancerous cervical lesions.Methods: This is a descriptive study performed in Gynecology Department of Civil Service Hospital, from August 2014 - December 2015 in 28 cases that underwent LEEP forCIN. LEEP was performed as day care procedure under intravenous anesthesia and patient was sent home six hours after procedure. Follow up and further treatment was done after final histopathological reports.Results: Highest percentage ofCIN, 32.14% (9) was seen among 30-39 years age with 16 (57.14%) of parity three and more. 17 (60.71%) presented clinic with symptoms (lower abdominal, backpain, pervaginal discharge) while 11 (39.28%) were diagnosed from routine Pap test. Histopathology revealed four (14.28%)CIN1, eight (28.57%)CIN2, 11(39.28%)CIN3, two adenocarcinoma in situ, one of invasive squamous cell carcinoma, chronic cervicitis and atrophic change with no dysplasia. Margins were negative (satisfactory) in 20 (71.42%) and positive in eight (28.57%) with endocervical involvement in two that required second LEEP while one underwent radical hysterectomy for final diagnosis of invasive squamous cell carcinoma.Conclusions: Hysterectomy is a radical procedure for preinvasive cervical lesions that can be treated with simple procedure like LEEP that saves time and financial resources.

scholarly journals The extra 1.5 cm makes the differences: reduced incidence of vaginal intraepithelial neoplasia after modified hysterectomy for CIN3/adenocarcinoma in situ (AIS) patients

2021 ◽  
Author(s):  
Lei Li ◽  
Xiaoyan Song ◽  
Xiaojie Feng ◽  
Xiaofeng Li ◽  
Zhenzhong Zhang ◽  
...  
Keyword(s):  
Blood Loss ◽  
Hospital Stay ◽  
Operative Time ◽  
Disease Free Survival ◽  
Intraepithelial Neoplasia ◽  
Postoperative Recurrence ◽  
Adenocarcinoma In Situ ◽  
Stay Time

Abstract Objectives To assess whether modified hysterectomy can improve locoregional control compared to the standard extrafascial hysterectomy for cervical high grade intraepithelial neoplasia 3 (CIN3)/adenocarcinoma in situ (AIS) patients. Methods A total of 135 CIN3/AIS patients from May 2014 to March 2018 were enrolled and randomized to different hysterectomy group and finally 128 patients were eligible for analysis, in which 60 patients received standard extrafascial hysterectomy and 68 patients received modified hysterectomy by removing extra 1.5cm of vagina. Intra-operative variables including operative time, estimated amount of blood loss, urinary catheter time, hospital stay time and postoperative complications, most importantly the postoperative recurrence and disease free survival (DFS) were compared and analyzed. Results Age, BMI and histology grade were comparable between these two groups. No significant differences were found at median surgical times, blood loss and postoperative hospital stay neither laparoscopicly nor abdominally, and neither was found about the incidences of fistulas, or other surgical complications. No incidences of prolonged urinary retention were found in both groups. With a median follow-up of 47.3 months (range 11–64 months), the modified hysterectomy group and had a significantly improved in DFS rate compared to the standard extrafascial hysterectomy group (P = 0.026). No disease related death occurred in the follow-up time. Conclusion With similar intra-operative variables operative time, modified hysterectomy appeared to provide the most reliable specimens and significantly reduced the postoperative vaginal recurrence rate for CIN3/AIS patients who choose remove their uterus when compared with standard extrafascial hysterectomy.

scholarly journals Survival Rate of Gastric Cancer Patients in Jordan: Secondary Data Analysis (Preprint)

2019 ◽  
Author(s):  
Ashraf Aqel ◽  
Yousef Khader ◽  
Kamal Arqoub ◽  
Omar Nimri
Keyword(s):  
Gastric Cancer ◽  
Survival Rate ◽  
Eastern Mediterranean ◽  
Secondary Analysis ◽  
Eastern Mediterranean Region ◽  
Secondary Data ◽  
Poorly Differentiated ◽  
Well Differentiated ◽  
Gastric Cancer Patients

BACKGROUND Gastric cancer accounts for 2.7% of all newly diagnosed cancer cases in Jordan. OBJECTIVE The aim of this study was to calculate the survival rate and its determinants among Jordanian patients who were diagnosed with gastric cancer between 2010 and 2014. METHODS A descriptive study was conducted based on secondary analysis of data from the Jordan Cancer Registry during the period of 2010-2014. Only cancer-related deaths were recorded as “death” in the survival analysis. RESULTS A total of 1388 new cases of gastric cancer were recorded between 2010 and 2014. Of these, 872 (62.8%) were Jordanians and 60.5% were males. The mean age at diagnosis was 58.9 years and the median follow-up time was 1.6 years. The 5-year survival rate decreased significantly from 89% in patients with well-differentiated cancer to 32% in patients with poorly differentiated cancer (<i>P</i>=.005). The overall 5-year survival rate was 37.7% and the median survival was 1.48 years (95% CI 1.179-1.783). The 5-year survival rate decreased significantly with increasing age and with advanced stage of the disease: the 5-year survival rate was 75% for localized-stage, 48% for regional-stage, and 22.7% for distant-metastasis disease (<i>P</i>=.005). CONCLUSIONS This study showed that the overall 5-year survival rate among patients with gastric cancer in Jordan between 2010 and 2014 was 37.7%, which is higher than the reported rates from different countries in the Eastern Mediterranean region such as Egypt.

scholarly journals Colon cancer in malrotated gut: A case report

2021 ◽  
pp. 386-387
Author(s):  
Arnab Gupta ◽  
Subrata Kumar Sahu ◽  
Samir Bhattacharya ◽  
Sudip Haldar
Keyword(s):  
Colon Cancer ◽  
Histopathological Examination ◽  
Incidental Finding ◽  
Vascular Anomaly ◽  
Right Hemicolectomy ◽  
Hepatic Flexure ◽  
Colon Cancers ◽  
Mesenteric Vessels ◽  
Well Differentiated

Malrotation of the gut is a rare congenital anomaly that mostly presents in the 1st month of life. Very rarely, it is found during adulthood either as an asymptomatic incidental finding or at autopsy. Presenting in adulthood with colon cancers is extremely rare. Here, we present the case of a middle-aged male patient with unexplained anemia which on investigation was found to have adenocarcinoma at the hepatic flexure of the colon. The staging computed tomography scan of the abdomen showed the growth at the hepatic flexure with malrotation of the gut. During the laparoscopic assessment, the cecum and ascending colon were found on the left side, and hence, a formal midline incision was made. Cecum was found on the left of the midline along with Ladd’s band. Extended right hemicolectomy was performed, dividing the Ladd’s band, taking care of the anomalous position of superior mesenteric vessels. The post-operative period was uneventful. Histopathological examination revealed this to be well-differentiated adenocarcinoma (pT3N1b). He thereafter received adjuvant chemotherapy and remains well after 5 years of follow-up. Presentation of malrotation of the gut in adulthood is seen in only 10–15% of cases as an incidental finding or at autopsy. Cancers in the colon in these patients are extremely rare. The treatment for colon cancer remains the same although one has to be careful about the vascular anomaly during the resection.

scholarly journals Survival Rate of Gastric Cancer Patients in Jordan: Secondary Data Analysis

10.2196/14359 ◽  
2020 ◽  
Vol 6 (2) ◽  
pp. e14359
Author(s):  
Ashraf Aqel ◽  
Yousef Khader ◽  
Kamal Arqoub ◽  
Omar Nimri
Keyword(s):  
Gastric Cancer ◽  
Survival Rate ◽  
Eastern Mediterranean ◽  
Secondary Analysis ◽  
Eastern Mediterranean Region ◽  
Secondary Data ◽  
Poorly Differentiated ◽  
Well Differentiated ◽  
Gastric Cancer Patients

Background Gastric cancer accounts for 2.7% of all newly diagnosed cancer cases in Jordan. Objective The aim of this study was to calculate the survival rate and its determinants among Jordanian patients who were diagnosed with gastric cancer between 2010 and 2014. Methods A descriptive study was conducted based on secondary analysis of data from the Jordan Cancer Registry during the period of 2010-2014. Only cancer-related deaths were recorded as “death” in the survival analysis. Results A total of 1388 new cases of gastric cancer were recorded between 2010 and 2014. Of these, 872 (62.8%) were Jordanians and 60.5% were males. The mean age at diagnosis was 58.9 years and the median follow-up time was 1.6 years. The 5-year survival rate decreased significantly from 89% in patients with well-differentiated cancer to 32% in patients with poorly differentiated cancer (P=.005). The overall 5-year survival rate was 37.7% and the median survival was 1.48 years (95% CI 1.179-1.783). The 5-year survival rate decreased significantly with increasing age and with advanced stage of the disease: the 5-year survival rate was 75% for localized-stage, 48% for regional-stage, and 22.7% for distant-metastasis disease (P=.005). Conclusions This study showed that the overall 5-year survival rate among patients with gastric cancer in Jordan between 2010 and 2014 was 37.7%, which is higher than the reported rates from different countries in the Eastern Mediterranean region such as Egypt.

Clinical Utility of Adjunctive High-Risk Human Papillomavirus DNA Testing in Women With Papanicolaou Test Findings of Atypical Glandular Cells

2010 ◽  
Vol 134 (1) ◽  
pp. 103-108
Author(s):  
Chengquan Zhao ◽  
Anca Florea ◽  
R. Marshall Austin
Keyword(s):  
Human Papillomavirus ◽  
High Risk ◽  
Cervical Intraepithelial Neoplasia ◽  
Pap Test ◽  
Intraepithelial Neoplasia ◽  
Adenocarcinoma In Situ ◽  
Test Results ◽  
Pap Tests

Abstract Context. Atypical glandular cell (AGC) Papanicolaou (Pap) test interpretations are challenging. Most biopsy findings are benign, but AGC results may also reflect highly significant noninvasive neoplastic and malignant histologic outcomes. High-risk human papillomavirus (hrHPV) test use with AGC Pap test results is evolving. Objective. To further evaluate the utility and limitations of hrHPV testing with AGC Pap tests. Design. Hospital records were searched for AGC Pap tests results from June 1, 2005, to August 31, 2007. Cases of AGC with hrHPV tests and histopathologic follow-up were included. Results. Of the 662 women with AGC Pap test results and follow-up analyzed, hrHPV results were available for 309 (46.7%) and were positive in 75 cases (24.3%). Among the 75 cases with hrHPV+ AGC results, 13 (17.3%) had cervical intraepithelial neoplasia grades 2/3, 10 (13.3%) had adenocarcinoma in situ, and 3 (4.0%) had cervical invasive adenocarcinoma, whereas for 234 women with hrHPV− results, 1 (0.4%) had cervical intraepithelial neoplasia grades 2/3, 1 (0.4%) had adenocarcinoma in situ, 1 each (0.4%) had cervical adenocarcinoma and ovarian carcinoma, and 8 (3.4%) had endometrial carcinoma. Conclusions. Positive hrHPV AGC results were most strongly associated with cervical intraepithelial neoplasia grades 2/3 and adenocarcinoma in situ in women younger than 50 years. Positive hrHPV AGC results were also present in all 3 cases of invasive cervical adenocarcinoma in women younger than 50 years. Of note, hrHPV− AGC results were present in 10 of 13 carcinomas (76.9%) detected after AGC Pap tests, all in women 40 years or older with endometrial adenocarcinomas (n  =  8), ovarian carcinoma (n  =  1), and cervical adenosquamous carcinoma in a woman (n  =  1) in her 50s. Testing for hrHPV after AGC Pap testing was most helpful in the detection of cervical intraepithelial neoplasia grades 2/3, adenocarcinoma in situ, and invasive cervical adenocarcinomas in women younger than 50 years.

Shimodaira-Taniguchi Conization Method: Its Utility and Reliability

2010 ◽  
Vol 20 (6) ◽  
pp. 1025-1030 ◽  
Author(s):  
Maki Matsumura ◽  
Tsuyoshi Ota ◽  
Nobuhiro Takeshima ◽  
Ken Takizawa
Keyword(s):  
Operation Time ◽  
Intraepithelial Neoplasia ◽  
Adenocarcinoma In Situ ◽  
Secondary Hemorrhage ◽  
Stage Ia ◽  
Cancer Of The Cervix ◽  
Lost To Follow Up ◽  
Frequency Current

Introduction:Introduced in 1992, the Shimodaira-Taniguchi conization procedure addresses the disadvantages of the loop electrosurgical excision procedure by relying on a high frequency current of 150 W and a triangular probe with a 0.25-mm linear excision electrode to extract a single informative specimen. We conducted a retrospective study to evaluate Shimodaira-Taniguchi conization as a conservative therapy for cervical intraepithelial neoplasia (CIN) and microinvasive cancer of the cervix.Methods:Subjects were 455 patients who underwent Shimodaira-Taniguchi conization for CIN, carcinoma in situ, adenocarcinoma in situ, or stage IA microinvasive cervical carcinoma at our hospital from January 2005 to December 2008. Patient follow-up ranged from 13 to 60 months. Clinical data were obtained and evaluated.Results:Mean operation time was 11 minutes, and average blood loss was 9.9 mL. Margins were positive in 178 (39.1%) cases. Postsurgical complications occurred in 61 patients, with secondary hemorrhage occurring in 46 patients. None required transfusion. None were lost to follow-up, and there was no disease-related death. Disease recurred in 6 (1.3%) patients: 4 with a positive excision margin and 2 with a negative margin. Cervical stenosis occurred in 15 (3.3%) patients, 3 of whom suffered cervical obstruction, including 1 with dysmenorrhea who underwent hysterectomy. In most cases (n = 357, 78%), a single adequate specimen was extracted.Conclusions:As a conservative treatment for CIN and microinvasive cervical cancer, Shimodaira-Taniguchi conization is useful. It is easy, provides adequate histologic specimens (often singular), and results in few postoperative complications.

Sign in / Sign up

Export Citation Format

Share Document