Cerebral Venous Thrombosis in the Superior Sagittal Sinus as a Rare Cause of a Paroxysmal Kinetic Tremor

Cerebral venous thrombosis (CVT) has a broad spectrum of clinical presentation compared to arterial etiology. Seizure is one of the common symptoms and is more frequent than in other stroke types. Hence, transient neurological symptoms in CVT patients are usually due to epileptic seizures, while transient repetitive movement disorder is extremely rare except as a complication of epilepsy. We report a case of CVT in the superior sagittal sinus with a 1-year history of paroxysmal kinetic tremor without evident epilepsy.

Download Full-text

Isolated cortical venous thrombosis after fetal demise

BMJ Case Reports ◽

10.1136/bcr-2018-228484 ◽

2019 ◽

Vol 12 (4) ◽

pp. e228484

Author(s):

Mohammad Al-Jundi ◽

Ghassan Al-Shbool ◽

Mohamad Muhailan ◽

Moutasem Aljundi ◽

Christian J Woods

Keyword(s):

Family History ◽

Early Diagnosis ◽

Venous Thrombosis ◽

Cerebral Venous Thrombosis ◽

Clinical Presentation ◽

Young Patients ◽

Fetal Demise ◽

History Of ◽

Venous Stroke ◽

Cortical Venous Thrombosis

Isolated cortical venous thrombosis (ICVT) occurring in the absence of dural venous thrombosis, constitutes about 2%–5% of all cerebral venous thrombosis. Its vague, non-specific presentation makes it a difficult and challenging diagnosis that needs an extensive workup especially in young patients. Outcome and prognosis depend mainly on early diagnosis and treatment. Here we discuss the clinical presentation, diagnosis and the treatment of a young woman diagnosed with ICVT with acute ischaemic venous stroke, in the setting of eclampsia and family history of coagulation disease.

Download Full-text

Superior sagittal sinus thrombosis as a focal point of pulmonary embolism

Russian neurological Journal ◽

10.30629/2658-7947-2021-26-1-39-44 ◽

2021 ◽

Vol 26 (1) ◽

pp. 39-44

Author(s):

G. R. Ramazanov ◽

A. E. Talypov ◽

A. A. Kanibolotskiy ◽

Kh. V. Korigova ◽

V. N. Stepanov ◽

...

Keyword(s):

Pulmonary Embolism ◽

Cerebrovascular Disease ◽

Venous Thrombosis ◽

Cerebral Venous Thrombosis ◽

Superior Sagittal Sinus ◽

Focal Point ◽

Sinus Thrombosis ◽

Sagittal Sinus ◽

Sagittal Sinus Thrombosis ◽

Superior Sagittal Sinus Thrombosis

This article represents the discussion of a clinical case of superior sagittal sinus thrombosis as a focal point of fatal pulmonary embolism. Pulmonary embolism is a life-threatening condition, with a mortality rate of up to 40%. The direct source of pulmonary embolism is deep vein thrombosis of the lower extremities and pelvis in 80–90% of all cases. The veins of the upper extremities and venous heart cause it less often. Pulmonary embolism in patients with cerebral venous thrombosis is observed in 1.4% of patients.Cerebral venous thrombosis is a cerebrovascular disease manifested by venous outflow disorders due to acute occlusion of the sinuses and veins of the brain. It requires immediate treatment in order to prevent the development of intracranial hemorrhage, venous infarction, disability and death. Cerebral venous thrombosis accounts for approximately 0.5% of all cases of cerebrovascular disease worldwide. In contrast to ischemic stroke, cerebral venous thrombosis is more common in younger patients. Currently, the diagnosis of cerebral venous thrombosis is based on neuroimaging data, and timely treatment leads to a decrease in disability and mortality.

Download Full-text

Cerebral Venous Thrombosis

10.4018/978-1-7998-7433-1.ch007 ◽

2022 ◽

pp. 113-119

Author(s):

Ozcan Demetgul

Keyword(s):

Venous Thrombosis ◽

Cerebral Venous Thrombosis ◽

Clinical Symptoms ◽

Rare Condition ◽

Epileptic Seizures ◽

Lateral Sinus ◽

Younger Adults ◽

Sagittal Sinus ◽

Vital Functions ◽

Visual Problems

Cerebral venous thrombosis (CVT) is a rare condition involving various symptoms that is mainly seen in younger adults. The most commonly involved are the superior sagittal sinus, lateral sinus, and simoid sinus. About 1% of all ischemic strokes are considered CVT. It is seen 3-fold more in young women. The incidence was estimated to be approx. 1/1000000. Cerebral venous sinuses are superficial and deep spaces, and they have vital functions. There are many symptoms. The most common complaint is headache (89%). Studies reported many different clinical symptoms. Neurological signs including motor and sensorial losses, impaired consciousness, speech disorder, epileptic seizures, visual problems (hemianopia, nystagmus, diplopia, and papilledema), and cranial nerve signs may be seen. The diagnosis is made primarily by suspecting the clinical condition and radiological presentation of thrombosis. The most basic diagnostic method is cranial imaging. Anticoagulants are the main method of treatment. The prognosis has improved over the last years thanks to early diagnosis.

Download Full-text

E-052 mechanical thrombectomy of the superior sagittal sinus using the penumbra device for cerebral venous thrombosis: a case report

Journal of NeuroInterventional Surgery ◽

10.1136/neurintsurg-2012-010455c.52 ◽

2012 ◽

Vol 4 (Suppl 1) ◽

pp. A68.3-A69

Author(s):

L Hnenny ◽

D Fiorella ◽

M Kelly

Keyword(s):

Case Report ◽

Venous Thrombosis ◽

Cerebral Venous Thrombosis ◽

Mechanical Thrombectomy ◽

Superior Sagittal Sinus ◽

Sagittal Sinus

Download Full-text

Anti-MOG Antibody Syndrome and Cerebral Sinovenous Thrombosis: A Cause–Effect Hypothesis

Journal of Pediatric Neurology ◽

10.1055/s-0040-1716345 ◽

2020 ◽

Author(s):

Alessandra Fontana ◽

Filippo Greco ◽

Pierluigi Smilari ◽

Andrea D. Praticò ◽

Agata Fiumara ◽

...

Keyword(s):

Venous Thrombosis ◽

Cerebral Venous Thrombosis ◽

Superior Sagittal Sinus ◽

Demyelinating Diseases ◽

Sagittal Sinus ◽

Cerebral Sinovenous Thrombosis ◽

Sinovenous Thrombosis ◽

Clinical Relationship ◽

Effect Hypothesis ◽

The Right

AbstractCerebral venous thrombosis is an uncommon event of stroke in childhood. Its origin is multifactorial and often it manifests with nonspecific symptoms that may overlap with underlying predisposing factors. Anti–myelin oligodendrocyte glycoprotein (MOG) antibody syndrome is a group of recently recognized acquired demyelinating diseases that occur more commonly in children, usually, with a favorable outcome. The association between cerebral venous thrombosis and demyelinating syndrome has been reported but their clinical relationship is matter of debate and various hypotheses have been advanced including intravenous (IV) steroid therapy and/or the consequence of a shared inflammatory-thrombotic process. Herein, we report the case of a child with anti-MOG antibody syndromes who developed a thrombosis of the superior sagittal sinus and of the right Trolard's vein.

Download Full-text

Cerebral Venous Thrombosis in Two Patients with Spontaneous Intracranial Hypotension

Case Reports in Neurological Medicine ◽

10.1155/2014/528268 ◽

2014 ◽

Vol 2014 ◽

pp. 1-7 ◽

Cited By ~ 1

Author(s):

M. C. Garcia-Carreira ◽

D. Cánovas Vergé ◽

J. Branera ◽

M. Zauner ◽

J. Estela Herrero ◽

...

Keyword(s):

Venous Thrombosis ◽

Cerebral Venous Thrombosis ◽

Intracranial Hypotension ◽

Superior Sagittal Sinus ◽

Spontaneous Intracranial Hypotension ◽

Cerebrospinal Fluid Leak ◽

Cerebral Veins ◽

Cortical Vein ◽

Sagittal Sinus ◽

Fluid Leak

Although few patients with spontaneous intracranial hypotension develop cerebral venous thrombosis, the association between these two entities seems too common to be simply a coincidental finding. We describe two cases of spontaneous intracranial hypotension associated with cerebral venous thrombosis. In one case, extensive cerebral venous thrombosis involved the superior sagittal sinus and multiple cortical cerebral veins. In the other case, only a right frontoparietal cortical vein was involved. Several mechanisms could contribute to the development of cerebral venous thrombosis in spontaneous intracranial hypotension. When spontaneous intracranial hypotension and cerebral venous thrombosis occur together, it raises difficult practical questions about the treatment of these two conditions. In most reported cases, spontaneous intracranial hypotension was treated conservatively and cerebral venous thrombosis was treated with anticoagulation. However, we advocate aggressive treatment of the underlying cerebrospinal fluid leak.

Download Full-text

Hyperthyroidism as a Precipitant Factor for Cerebral Venous Thrombosis: A Case Report

Journal of Investigative Medicine High Impact Case Reports ◽

10.1177/2324709620949309 ◽

2020 ◽

Vol 8 ◽

pp. 232470962094930

Author(s):

Ahmed Elkhalifa Elawad Elhassan ◽

Mohammed Omer Khalil Ali ◽

Amina Bougaila ◽

Mohammed Abdelhady ◽

Hassan Abuzaid

Keyword(s):

Case Report ◽

Superior Sagittal Sinus ◽

Sinus Thrombosis ◽

Cerebral Venous Sinus Thrombosis ◽

Laboratory Findings ◽

Sagittal Sinus ◽

History Of ◽

Sagittal Sinus Thrombosis ◽

Superior Sagittal Sinus Thrombosis

Cerebral venous sinus thrombosis (CVT) is an uncommon yet serious condition. While CVT has many known precipitants and etiologies, hyperthyroidism as a precipitant of CVT is not well understood. This study reported a case of a 41-year-old male with a 4-year history of hyperthyroidism presented with seizure. Consequently, a diagnosis of superior sagittal sinus thrombosis was confirmed by computed tomography and magnetic resonance (MR) venograms. Extensive investigations yielded no apparent underlying cause, but laboratory findings were consistent with uncontrolled hyperthyroidism. The patient improved rapidly following anticoagulation. Follow-up MR and MRV scans 2 months after treatment revealed full recanalization of the superior sagittal sinus. This case report highlighted hyperthyroidism, as a procoagulant condition, resulting specifically in superior sagittal sinus thrombosis.

Download Full-text

Cerebral Venous Sinus Thrombosis in Women: Subgroup Analysis of the VENOST Study

Stroke Research and Treatment ◽

10.1155/2020/8610903 ◽

2020 ◽

Vol 2020 ◽

pp. 1-8

Author(s):

Derya Uluduz ◽

Sevki Sahin ◽

Taskin Duman ◽

Serefnur Ozturk ◽

Vildan Yayla ◽

...

Keyword(s):

Venous Thrombosis ◽

Deep Venous Thrombosis ◽

Sinus Thrombosis ◽

Previous History ◽

Epileptic Seizures ◽

Cerebral Venous Sinus Thrombosis ◽

Venous Sinus ◽

Venous Sinus Thrombosis ◽

History Of ◽

The Mean

Background. Early diagnosis of cerebral venous sinus thrombosis (CVST) associated with reproductive health-related risk factors (RHRF) including pregnancy, puerperium, and oral contraceptive (OC) use can prevent severe neurological sequelae; thus, the symptoms must be documented in detail for each group. Methods. Out of 1144 patients with CVST, a total of 777 women were enrolled from a multicenter for the study of cerebral venous sinus thrombosis (VENOST). Demographic, biochemical, clinical, and radiological aspects were compared for 324 cases with RHRF and 453 cases without RHRF. Results. The mean age of the RHRF (-) group (43.2 ± 13 years) was significantly higher than of the RHRF (+) group (34±9 years). A previous history of deep venous thrombosis (3%), isolated cavernous sinus involvement (1%), cranial neuropathy (13%), comorbid malignancy (7%), and its disability scores after 12 months (9%) were significantly higher in the RHRF (-) group. The RHRF (+) group consisted of 44% cases of puerperium, 33% cases of OC users and 23% of pregnant women. The mean age was found to be higher in OC users (38±9 years). A previous history of deep venous thrombosis was slightly higher in the pregnancy subgroup (4%). Epileptic seizures were more common in the puerperium group (44%). Conclusion. The results of our study indicate that the risk of CSVT increases parallel to age, OC use, and puerperium period. In addition, when considering the frequency of findings and symptoms, epileptic seizures in the puerperium subgroup of the RHRF (+) group and malignancies in the RHRF (-) group may accompany the CSVT. In daily practice, predicting these risks for the CSVT and early recognition of the symptoms will provide significant benefits to patients.

Download Full-text