scholarly journals Successful Treatment of Neonatal Respiratory Transitional Disorder with Pulmo/Vivianit comp. in 2 Cases

2017 ◽  
Vol 24 (3) ◽  
pp. 172-174
Author(s):  
Benedikt M. Huber ◽  
Dirk Bassler
Keyword(s):  
Intensive Care ◽  
Case Report ◽  
Adverse Effects ◽  
Therapeutic Approach ◽  
Newborn Infants ◽  
Routine Practice ◽  
Off Label ◽  
Therapeutic Measures ◽  
High Level

Background: Disorders of the respiratory transition at birth are major reasons for neonates being admitted to intensive care units and separated from their mothers. This has potential long-lasting consequences for the mother-infant interaction as well as the long-term development of the child. There is an urgent need for effective preventive and therapeutic measures for this frequent disorder. Case Report: We report the cases of 2 newborn infants with respiratory transitional disorder treated off-label with the anthroposophic medicament Pulmo/Vivianit comp. based on pathophysiological considerations and on particular parental request. In both cases, an immediate and sustainable response could be documented without adverse effects. Conclusion: This new therapeutic approach merits further attention in clinical research but cannot be recommended for routine practice before more high-level evidence is available.

scholarly journals Intracerebral Haemorrhage with Choriocarcinoma in a Teenager - A Case Report

2019 ◽  
Vol 37 (3) ◽  
pp. 151-155
Author(s):  
Sukriti Das ◽  
Md Manirul Islam ◽  
Md Mamunur Rashid ◽  
Md Reaz Ahmed Howlader ◽  
Sharbori Dey ◽  
...  
Keyword(s):  
Case Report ◽  
Ct Scan ◽  
Intracerebral Haemorrhage ◽  
Reproductive Age ◽  
High Concentration ◽  
Intracranial Metastasis ◽  
Term Survival ◽  
X Ray ◽  
High Level

Intracerebral haemorrhage is one of the uncommon initial CNS manifestations of choriocarcinoma in reproductive age group women. Disease is usually diagnosed by history, clinical examinations and investigations like CT scan of brain and chest, MRI of brain, USG, X-ray chest P/A view and high level of â-hCG in serum and CSF. Overall prognosis of this disease is generally good (80-90% long term survival with chemotherapy and radiotherapy). But intracranial metastasis has poor prognosis which comprises 3-28% of choriocarcinoma. Most intracranial metastasis occurs late in the course of disease but 20% experiences as first sign. Our patient is a teenager girl presented with convulsion and loss of consciousness. CT scan of brain revealed hemorrhage in right fronto-parietal region with ventricular extension, X-ray chest P/A view shows metastasis in mid zone of right lung, USG shows invasion in posterior myometrium and high concentration of serum â-hCG (273400 mUI/ ml) confirmed our diagnosis. This case report describes that the conservative treatment with radiotherapy and chemotherapy gives good outcome of with metastasic intracerebral haemorrhage with choriocarcinoma is rewarding with farther radio and chemotherapy. J Bangladesh Coll Phys Surg 2019; 37(3): 151-155

scholarly journals Long-Term Rehabilitation for Intensive Care Unit-acquired Weakness with Orthostatic Hypotension Following Severe Pneumonia：A Case Report

2018 ◽  
Vol 55 (6) ◽  
pp. 508-515
Author(s):  
Satoshi Endo ◽  
Michio Kobayashi ◽  
Takafumi Tani ◽  
Shohei Toyama ◽  
Ryota Seo ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Case Report ◽  
Orthostatic Hypotension

Mood Stabilizer Loading Versus Titration in Acute Mania: Audit of Clinical Practice

2008 ◽  
Vol 42 (11) ◽  
pp. 955-962 ◽  
Author(s):  
Amanda Wheeler ◽  
Gail Robinson ◽  
Allen Fraser
Keyword(s):  
Intensive Care ◽  
Length Of Stay ◽  
Adverse Effects ◽  
Legal Status ◽  
Clinical Decision Making ◽  
Average Length ◽  
Mood Stabilizer ◽  
Serum Levels ◽  
High Serum ◽  
Routine Practice

Objective: The aim of the present study was to investigate whether the use of a loading strategy with lithium or valproate followed recommended practice and second, whether this had any impact on indicators of outcome in acutely manic inpatients. Method: A 12 month retrospective review of admissions to two adult psychiatric units in Auckland, New Zealand, was conducted. Demographic, legal status, psychiatric admissions, outcome indicators (length of stay, intensive care and seclusion use) and medication data were collected for all patients with a diagnosis of acute bipolar mania who started mood stabilizer treatment within 3 days of admission (n=93). Serum levels and adverse effects were also recorded. Results: In 46.2% of admissions a loading strategy was prescribed, and lithium was the treatment choice in two-thirds of admissions. Serum levels were taken inconsistently, particularly for valproate. No difference was found between loading and titrating for the assessed outcomes in routine practice; average length of stay was 30.2 days; most patients (71.0%) spent time in intensive care (average 8.4 days) and 33.3% spent time in seclusion. More adverse effects occurred with loading (51.2%) compared to titrating (36.0%), particularly with lithium. Conclusion: The literature supports a strong link between rapidly attained high serum levels and positive outcomes. The present study found inconsistent and infrequent measurement of levels, which was not in accord with recommended practice. Frequent monitoring of serum levels to support dosing decisions is important to inform better clinical decision making, especially when a loading strategy is used. This may explain the less than optimal outcomes (with respect to rapid resolution of mania and hospital discharge) that were found, irrespective of dosing strategy.

scholarly journals Covid - 19 Associated Pulmonary Aspergillosis (CAPA) in Critically Ill Patients : A Case Report

2021 ◽  
Vol 10 (9) ◽  
pp. 402-406
Author(s):  
Himadri Dutta Vandana Sinha ◽  
Anup Jyoti Dutta Pinku Sarma
Keyword(s):  
Intensive Care ◽  
Case Report ◽  
Early Diagnosis ◽  
Critically Ill Patients ◽  
Private Hospital ◽  
Standard Treatment ◽  
Pulmonary Aspergillosis ◽  
The World ◽  
Different Parts

In the present study report three cases of covid-19 associated Pulmonary Aspergillosis from covid ICU of a private hospital. There is increased incidence of different co infections including fungal from severe cases of covid-19 requiring ICU care from different parts of the world. None of the patients in our report had any predisposing lung conditions and none of them were on long term steroids treatment. Out of the three cases, two cases clinically improved dramatically after initiation of antifungals. Second case deteriorated even before culture diagnosis was established and the patient died before antifungals could be started. So, possibility of a fungal infection should be always ruled out in all COVID-19 pneumonia cases without any clinical improvement after standard treatment and intensive care. Early diagnosis and treatment will help improve clinical outcomes in such cases.

scholarly journals Late effects of cancer treatment: consequences for long-term brain cancer survivors

2020 ◽  
Author(s):  
Montse Alemany ◽  
Roser Velasco ◽  
Marta Simó ◽  
Jordi Bruna
Keyword(s):  
Adverse Effects ◽  
Clinical Suspicion ◽  
Secondary Effects ◽  
Cancer Treatments ◽  
Tumor Patients ◽  
Secondary Neoplasms ◽  
Late Adverse Effects ◽  
High Level ◽  
Multiple Domains

Abstract Late adverse effects of cancer treatments represent a significant source of morbidity and also financial hardship among brain tumor patients. These effects can be produced by direct neurologic damage of the tumor and its removal, and/or by complementary treatments such as chemotherapy and radiotherapy, either alone or combined. Notably, young adults are the critical population that faces major consequences because the early onset of the disease may affect their development and socioeconomic status. The spectrum of these late adverse effects is large and involves multiple domains. In this review we classify the main long-term adverse effects into 4 sections: CNS complications, peripheral nervous system complications, secondary neoplasms, and Economic impact. In addition, CNS main complications are divided into nonfocal and focal symptoms. Owing to all the secondary effects mentioned, it is essential for physicians to have a high level of clinical suspicion to prevent and provide early intervention to minimize their impact.

scholarly journals Successful medical management of insulinoma with diazoxide for 27 years

2020 ◽  
Vol 2020 ◽  
Author(s):  
Annabelle M Warren ◽  
Duncan J Topliss ◽  
Peter Shane Hamblin
Keyword(s):  
Case Report ◽  
Adverse Effects ◽  
Medical Management ◽  
List Type ◽  
Successful Management ◽  
Pet Ct ◽  
Effective Option ◽  
Pet Ct Scan ◽  
Learning Points

Summary Despite improvements in localisation techniques and surgical advances, some patients with insulinoma will not be cured by surgery or may not be suitable for surgery. Medical management with diazoxide is an option for such cases. This case report details 27 years of successful management of insulinoma using diazoxide. It has been effective and safe, with only minor adverse effects. Learning points: Long term diazoxide use can be a safe, effective option for insulinoma when it cannot be localised or removed surgically. Common adverse effects include peripheral oedema, hyperuricaemia, and hirsutism. 68Ga-NOTA-exendin-4 PET/CT scan should be considered for insulinoma localisation when other modalities have been unhelpful.

scholarly journals Successful treatment with adjunctive lacosamide in a patient with long term “drug resistant” focal epilepsy

2014 ◽  
Vol 22 (1) ◽  
pp. 51-55
Author(s):  
Walter Fröscher ◽  
Alois Rauber
Keyword(s):  
Case Report ◽  
Focal Epilepsy ◽  
Adjunctive Treatment ◽  
High Dose ◽  
Seizure Freedom ◽  
Drug Resistant ◽  
Off Label ◽  
Number Of Patients ◽  
Drug Resistant Epilepsy

SUMMARY Introduction. A significant number of patients suffering from epilepsy prove to be resistant to antiepileptic drugs (AEDs). Recent studies, however, suggest that 10–20% of seemingly drug resistant patients may still become seizure-free under the influence of subsequent dosage modifications. Case report. We report on a young man with cryptogenic focal epilepsy. He had his first seizure at the age of fifteen. His seizure frequency was decreased during the following 11 years. However, seizure-freedom was never achieved even though he was treated with twelve to fourteen different AEDs during this time. Intensive presurgical evaluations did not allow identification of a surgically remediable focus. Adjunctive treatment with lacosamide 400 mg/day was not successful. However, the patient became seizure-free immediately after an increase of the lacosamide dose up to 500 mg/day. The patient is now seizure-free for more than two years based on a combination of 500 mg lacosamide and 350 mg lamotrigine, followed by 550 mg and 250 mg, respectively. Discussion and conclusion. This case report highlights that there is always a chance that modifying the medication can result in a drug-resistant epilepsy patient experiencing a significant reduction of seizures and becoming seizure-free. The decisive step in this example was the off-label prescription of a high dose of lacosamide which the patient tolerated well.

An Unusual and Rare Complication of LeFort I Osteotomy: a case report

2020 ◽  
Author(s):  
Mehdi Bemanali ◽  
Shahabaldin Azizi ◽  
Zahra Mousavi ◽  
Mahdieh Karimizadeh
Keyword(s):  
Case Report ◽  
Pulmonary Thromboembolism ◽  
Simple Procedure ◽  
Rare Complication ◽  
Long Term Results ◽  
Unusual Complication ◽  
Dentofacial Deformities ◽  
Life Threatening ◽  
High Level

The LeFort I osteotomy is a versatile and simple procedure used by oral and maxillofacial surgeons for correction of congenital, developmental, or acquired dentofacial deformities. This technique is widely used due to its low complication rate such as rare, life-threatening events, reliable long-term results, and a high level of patient satisfaction. This report presents a case of LeFort I osteotomy resulting in an unusual complication of pulmonary thromboembolism.

scholarly journals Célhőmérséklet a tartós újraélesztés utáni komplex intenzív kezelés során. Állásfoglalás az enyhe terápiás hypothermia mellett

2019 ◽  
Vol 160 (46) ◽  
pp. 1840-1844
Author(s):  
Endre Zima
Keyword(s):  
Intensive Care ◽  
Cellular Level ◽  
Temperature Management ◽  
Hypoxic Brain Injury ◽  
Hypoxic Brain ◽  
Organ Specific ◽  
Related Group ◽  
Pros And Cons ◽  
High Level

Abstract: If the patient undergoes a long-term resuscitation or remains comatose as part of the post-cardiac arrest syndrome (PCAS), organ-specific intensive care is urged to aim hemodynamic stabilisation, normalisation of organ perfusion and prevention of injuries at cellular level. One of the basic measures of PCAS intensive care is to prevent hypoxic brain injury by mild therapeutic hypothermia (THT). The physiological changes of the human body at hypothermic conditions require high level monitoring and specially focused intensive care limiting its implementation. The multicentric, controlled, randomized targeted temperature management (TTM) trial published in 2013 compared the TTM against the THT in the treatment of PCAS patients. The equal outcome of the 2 methods has partly changed the practice of the intensivists in the treatment of such patients. This manuscript gives the pros and cons for each therapeutic method in post-resuscitation therapy. Nevertheless, the author shows the possible implementations and the DRG (diagnosis-related group) reimbursement of the method in Hungary. Orv Hetil. 2019; 160(46): 1840–1844.

Sign in / Sign up

Export Citation Format

Share Document