scholarly journals Ectopic Pancreatic Tissue Adherent to the External Gallbladder Wall

2018 ◽  
Vol 12 (1) ◽  
pp. 170-175 ◽  
Author(s):  
Ioannis M. Koukourakis ◽  
Meltem S. Perente Memet ◽  
Maria Kouroupi ◽  
Konstantinos Simopoulos
Keyword(s):  
Young Women ◽  
Gallbladder Wall ◽  
Pancreatic Tissue ◽  
Chronic Cholecystitis ◽  
Tissue Type ◽  
Pathological Examination ◽  
Fatty Tissue ◽  
Abdominal Symptoms ◽  
Ectopic Pancreatic Tissue

Heterotopic pancreatic tissue can be found in the gastrointestinal tract, with the stomach and small bowel being the most common sites of localization. The gallbladder is seldom affected. Here, we report 2 cases of ectopic pancreas within the fatty tissue adherent to the organ wall. Both cases concerned young women (31 and 36 years old) who were treated with a laparoscopic cholecystectomy due to persistent abdominal symptoms thought to be related to chronic cholecystitis. Pathological examination revealed the presence of ectopic pancreatic tissue type 1.

scholarly journals Ectopic thyroid presenting as a gallbladder mass

2010 ◽  
Vol 92 (4) ◽  
pp. e4-e6 ◽  
Author(s):  
Kuo Liang ◽  
Jia Feng Liu ◽  
Yue Hua Wang ◽  
Guo Cai Tang ◽  
Liang Hong Teng ◽  
...  
Keyword(s):  
Thyroid Tissue ◽  
Gallbladder Wall ◽  
Chronic Cholecystitis ◽  
Ectopic Thyroid ◽  
Pathological Examination ◽  
Embryological Development ◽  
Ectopic Thyroid Tissue ◽  
And Migration

The ectopic thyroid tissue is the result of abnormality in embryological development and migration. Ectopic thyroid tissue located in or adjacent to the gallbladder wall is extremely rare with only two cases reported since 1969. These cases were all identified incidentally by pathological examination after cholecystectomy for acute or chronic cholecystitis. We here report a case of ectopic thyroid tissue presenting as a gallbladder mass in a 60-year-old woman who underwent cholecystectomy. Ectopic thyroid tissue in the gallbladder wall was confirmed by histopathology.

Demonstration of three distinct high molecular weight complexes between plasminogen activator inhibitor type 1 and tissue type plasminogen activator.

2021 ◽  
Author(s):  
Tae Ito ◽  
Yuko Suzuki ◽  
Hideto Sano ◽  
Naoki Honkura ◽  
Francis J Castellino ◽  
...  
Keyword(s):  
Molecular Weight ◽  
Plasminogen Activator ◽  
Plasminogen Activator Inhibitor ◽  
Tissue Type ◽  
Type Plasminogen Activator ◽  
Sds Page ◽  
Inhibitor Type ◽  
Activator Inhibitor Type ◽  
Pai 1

Background: Details of the molecular interaction between tissue type plasminogen activator (tPA) and plasminogen activator inhibitor type-1 (PAI-1) remain unknown. Methods and Results: Three distinct forms of high molecular weight complexes are demonstrated. Two of the forms were detected by mass spectrometry. The high molecular mass detected by MALDI-TOF MS spectrometry was 107,029 Da, which corresponds to the sum of molecular masses of the intact tPA (65,320 Da) and the intact PAI-1 (42,416 Da). The lower molecular mass was 104,367 Da and is proposed to lack the C-terminal bait peptide of PAI-1 (calculated mass, 3,804 Da) which was detected as a 3,808 Da fragment. When the complex was analyzed by SDS-PAGE, only a single band was observed. However, after treatment by SDS and Triton X-100, two distinct forms of the complex with different mobilities were shown by SDS-PAGE. The higher molecular weight band demonstrated specific tPA activity on fibrin autography, whereas the lower molecular weight band did not. Peptide sequence analysis of these two bands, however, unexpectedly revealed the existence of the C-terminal cleavage peptide in both bands and its amount was less in the upper band. In the upper band, the sequences corresponding to the regions at the interface between two molecules in its Michaelis intermediate were diminished. Thus, these two bands corresponded to distinct nonacyl-enzyme complexes, wherein only the upper band liberated free tPA under the conditions employed. Conclusion: These data suggest that under physiological conditions a fraction of the tPA-PAI-1 population exists as non-acylated-enzyme inhibitor complex.

scholarly journals Ectopic pancreatic tissue located in the subserosa of the jejunum: A case report

2013 ◽  
Vol 2 (6) ◽  
Author(s):  
C Barkolias ◽  
N Orfanos ◽  
V Kalles ◽  
G Georgiou ◽  
I Papapanagiotou ◽  
...  
Keyword(s):  
Case Report ◽  
Pancreatic Tissue ◽  
Ectopic Pancreatic Tissue

Crohn’s disease of the gallbladder

2021 ◽  
Vol 14 (9) ◽  
pp. e243579
Author(s):  
Callam Scott ◽  
Amit Patel ◽  
Noori Maka ◽  
Jonathan C MacDonald
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Gallstone Formation ◽  
Right Hemicolectomy ◽  
Chronic Cholecystitis ◽  
Pathological Examination ◽  
Key Factors ◽  
Chronic Inflammatory Condition ◽  
History Of ◽  
Lymphoid Aggregates

Crohn’s disease (CD) is a chronic inflammatory condition, which typically involves the small and large bowel but can affect any part of the gastrointestinal tract. Common symptoms include abdominal pain, diarrhoea, fatigue, weight loss and malnutrition. Complications of CD include gallstone formation and cholecystitis. Impaired reabsorption of bile salts in the small bowel and CD-related surgeries are key factors in the development of CD-related gallstones, although other factors are also important. Direct CD-related inflammation of the gallbladder is very unusual and the typical histological features of CD are rarely encountered in cholecystectomy specimens of individuals with CD. We present a case of a man in his early 60s with CD, previous right hemicolectomy and a history of gallstones, who presented with chronic cholecystitis. Following cholecystectomy, pathological examination of the gallbladder unexpectedly demonstrated typical features of CD, including lymphoid aggregates and non-caseating mucosal granulomata.

A retroperitoneal neuroendocrine tumor in ectopic pancreatic tissue

2013 ◽  
Vol 2 (3) ◽  
pp. 168 ◽  
Author(s):  
HusseinHassan Okasha ◽  
Fahim Al-Bassiouni ◽  
MonirAbo El-Ela ◽  
EmadHamza Al-Gemeie ◽  
Reem Ezzat
Keyword(s):  
Neuroendocrine Tumor ◽  
Pancreatic Tissue ◽  
Ectopic Pancreatic Tissue
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