Association between the Cardio-Ankle Vascular Index and Diabetes Mellitus-Related Peripheral Arterial Disease in Chronic Hemodialysis Patients

Background: Peripheral arterial disease (PAD) has increased in association with the increase in the numbers of patients with kidney disease or diabetes. The aim of this study was to assess the prevalence of PAD in hemodialysis patients with diabetes. Methods: To examine the usefulness of the cardio-ankle vascular index (CAVI) to screen for the presence of PAD, cross-sectional studies of 100 patients undergoing chronic hemodialysis were performed. The CAVI and other inflammatory markers were evaluated. Results: The CAVI was markedly elevated in patients with a history of PAD or cardiovascular disease. When dialysis patients were classified on the basis of CAVI quartiles, increased CAVI was associated with other risk factors for PAD. Conclusion: The prevalence of PAD is high in elderly diabetic patients on hemodialysis. The present findings suggest that the CAVI can be a useful index that predicts the occurrence of macrovascular complications in dialysis patients with diabetes.

Download Full-text

PENIS NECROSIS IN A DIABETIC PATIENT AND CHRONIC HEMODIALYSIS

International Journal of Advanced Research ◽

10.21474/ijar01/12544 ◽

2021 ◽

Vol 9 (03) ◽

pp. 01-04

Author(s):

Khalid Ouatar ◽

◽

Cheikh Saad Bouh Khatraty ◽

Mustapha Ahsaini ◽

Soufiane Mellas ◽

...

Keyword(s):

Peripheral Arterial Disease ◽

Chronic Kidney Failure ◽

Arterial Disease ◽

Chronic Hemodialysis ◽

Diabetic Patients ◽

Rare Entity ◽

Patients With Diabetes ◽

Partial Amputation ◽

Life Threatening ◽

Peripheral Arterial

Penis necrosis is a rare entity. Most often serious and it could have life-threatening prognosis because in the majority of cases its found in severe peripheral arterial disease it occurs mainly in chronic kidney failure patients with diabetes or diabetic patients. Penis has a very good blood supply Arterial obstruction secondary to arteriolic calcification can cause distal necrosis. the treatment is essentially surgical. We report a case of penis necrosis treated by partial amputation.

Download Full-text

Peripheral Arterial Disease among Adult Diabetic Patients Attending a Large Outpatient Diabetic Clinic at a National Referral Hospital in Uganda: A Descriptive Cross Sectional Study

PLoS ONE ◽

10.1371/journal.pone.0105211 ◽

2014 ◽

Vol 9 (8) ◽

pp. e105211 ◽

Cited By ~ 10

Author(s):

Raymond Mbayo Mwebaze ◽

Davis Kibirige

Keyword(s):

Peripheral Arterial Disease ◽

Arterial Disease ◽

Cross Sectional Study ◽

Referral Hospital ◽

Diabetic Patients ◽

Sectional Study ◽

Cross Sectional ◽

Diabetic Clinic ◽

Peripheral Arterial ◽

National Referral Hospital

Download Full-text

The prevalence of peripheral arterial disease in diabetic subjects in south-west Nigeria

African Journal of Primary Health Care & Family Medicine ◽

10.4102/phcfm.v4i1.354 ◽

2012 ◽

Vol 4 (1) ◽

Cited By ~ 5

Author(s):

Bolaji O. Oyelade ◽

Akintayo D. OlaOlorun ◽

Louis O. Odeigah ◽

Isaac O. Amole ◽

Olufemi S. Adediran

Keyword(s):

Peripheral Arterial Disease ◽

Intermittent Claudication ◽

Objective Assessment ◽

Ankle Brachial Index ◽

Arterial Disease ◽

Cross Sectional ◽

Index Measurement ◽

Clinical Methods ◽

History Of ◽

Peripheral Arterial

Background: Peripheral arterial disease (PAD) is rarely sought for and generally underdiagnosed even in diabetics in developing countries like Nigeria. PAD is easily detected and diagnosed by the ankle-brachial index, a simple and reliable test. Objectives: To determine the prevalence of PAD in diabetic subjects aged 50–89 years and the value of ankle-brachial index measurement in the detection of PAD.Method: A cross-sectional descriptive study of 219 diabetic subjects aged 50–89 years was carried out. The participants were administered a pre-tested questionnaire and measurement of ankle-brachial index (ABI) was done. The ankle-brachial index < 0.90 was considered equivalent to peripheral arterial disease.Results: The overall prevalence of PAD was 52.5%. The prevalence of symptomatic PAD was 28.7% whilst that of asymptomatic PAD was 71.3%. There were a number of associations with PAD which included, age (p < 0.05), sex (p < 0.05), and marital status (p < 0.05). The use of the ankle-brachial index in the detection of PAD was clearly more reliable than the clinical methods like history of intermittent claudication and absence or presence of pedal pulses.Conclusion: The prevalence of PAD is relatively high in diabetic subjects in the southwestern region of Nigeria. Notable is the fact that a higher proportion was asymptomatic. Also the use of ABI is of great value in the detection of PAD as evidenced by a clearly more objective assessment of PAD compared to both intermittent claudication and absent pedal pulses.

Download Full-text

Prevalence, clinical characteristics, and predictors of peripheral arterial disease in hemodialysis patients: a cross-sectional study

BMC Nephrology ◽

10.1186/s12882-019-1468-x ◽

2019 ◽

Vol 20 (1) ◽

Cited By ~ 3

Author(s):

Radislav R. Ašćerić ◽

Nada B. Dimković ◽

Goran Ž. Trajković ◽

Biljana S. Ristić ◽

Aleksandar N. Janković ◽

...

Keyword(s):

Peripheral Arterial Disease ◽

Clinical Characteristics ◽

Arterial Disease ◽

Cross Sectional Study ◽

Hemodialysis Patients ◽

Sectional Study ◽

Cross Sectional ◽

Peripheral Arterial

Download Full-text

Prevalence of Peripheral Arterial Disease and Associated Vascular Risk Factors in 65-Years-Old People of Northern Barcelona

Journal of Clinical Medicine ◽

10.3390/jcm10194467 ◽

2021 ◽

Vol 10 (19) ◽

pp. 4467

Author(s):

Gabriela Gonçalves-Martins ◽

Daniel Gil-Sala ◽

Cristina Tello-Díaz ◽

Xavier Tenezaca-Sari ◽

Carlos Marrero ◽

...

Keyword(s):

Risk Factors ◽

Peripheral Arterial Disease ◽

Strong Association ◽

Ankle Brachial Index ◽

Arterial Disease ◽

Cross Sectional ◽

Screening Programs ◽

History Of ◽

Peripheral Arterial ◽

Male Subjects

Objective: To determine the prevalence and risk factors associated with peripheral arterial disease (PAD) in Northern Barcelona at 65 years of age. Methods: A single-center, cross-sectional study, including males and females 65 years of age, health care cardholders of Barcelona Nord. PAD was defined as an ankle–brachial index (ABI) < 0.9. Attending subjects were evaluated for a history of common cardiovascular risk factors. A REGICOR score was obtained, as well as a physical examination and anthropometric measurements. Results: From November 2017 to December 2018, 1174 subjects were included: 479 (40.8%) female and 695 (59.2%) male. Overall prevalence of PAD was 6.2% (95% CI: 4.8–7.6%), being 7.9% (95% CI: 5.9–9.9%) in males and 3.8% (95% CI: 2.1–5.5%) in females. An independent strong association was seen in male smokers and diabetes, with ORs pf 7.2 (95% CI: 2.8–18.6) and 1.8 (95% CI: 1.0–3.3), respectively, and in female smokers and hypertension, with ORs of 5.2 (95% CI: 1.6–17.3) and 3.3 (95% CI: 1.2–9.0). Male subjects presented with higher REGICOR scores (p < 0.001). Conclusion: Higher-risk groups are seen in male subjects with a history of smoking and diabetes and female smokers and arterial hypertension, becoming important subgroups for our primary healthcare centers and should be considered for ABI screening programs.

Download Full-text

Serum gamma-glutamyltransferase is not associated to peripheral arterial disease in type 2 diabetic patients: Cross-sectional findings

Atherosclerosis ◽

10.1016/j.atherosclerosis.2008.07.006 ◽

2009 ◽

Vol 203 (1) ◽

pp. 49-50 ◽

Cited By ~ 2

Author(s):

Cristina Bianchi ◽

Giuseppe Penno ◽

Stefano Del Prato ◽

Roberto Miccoli

Keyword(s):

Peripheral Arterial Disease ◽

Arterial Disease ◽

Diabetic Patients ◽

Type 2 Diabetic Patients ◽

Cross Sectional ◽

Gamma Glutamyltransferase ◽

Peripheral Arterial ◽

Type 2 Diabetic

Download Full-text

Association Between Heart Rate-corrected QT Interval and Severe Peripheral Arterial Disease in Patients with Type 2 Diabetes and Foot Ulcers:Aa Case Control Study

10.21203/rs.3.rs-95090/v1 ◽

2020 ◽

Author(s):

Jing Hong ◽

Wen-Yue Liu ◽

Xiang Hu ◽

Fei-Fei Jiang ◽

Ze-Ru Xu ◽

...

Keyword(s):

Heart Rate ◽

Peripheral Arterial Disease ◽

Early Stage ◽

Arterial Disease ◽

Cross Sectional Study ◽

Qtc Interval ◽

Cross Sectional ◽

Logistic Analysis ◽

Patients With Diabetes ◽

Peripheral Arterial

Abstract Background: Half of patients with diabetes and foot ulcers (DFUs) have co-existing peripheral arterial disease (PAD). Prolonged heart rate-corrected QT (QTc) interval was found to be associated with PAD in a general population. The goal of the present study was to investigate the relationship between QTc interval and PAD in patients with DFUs.Methods: The present multi-center cross-sectional study enrolled 281 patients with DFUs. Severity of PAD was classified as no-severe PAD group (no obvious abnormality or plaques) and severe PAD group (stenosis or occlusion) according to duplex ultrasonography. QTc was calculated according to the Bazett formula. The study population was divided into subgroups based on the QTc tertiles. Results: The patients with severe PAD had longer QTc interval (P = 0.004) and higher prevalence of prolonged QTc (P = 0.042) than those with no-severe PAD. After adjustment for gender and age, partial correlation analysis revealed positive relationship of QTc with prevalence of severe DFUs (r = 0.194, P = 0.001) and severe PAD (r = 0.118, P = 0.048). Univariate logistic analysis showed that the QTc was positively associated with severe PAD (odds ratio [OR] = 1.010, P = 0.014). Compared to those in lowest tertile of QTc, the ORs for severe PAD were increased significantly and independently for those in upper tertiles of QTc (both P < 0.05). Conclusions: Prolonged QTc interval was independently associated with severe PAD in patients with DFUs, which might indicate the worse progression of peripheral atherosclerosis in early stage for this population.

Download Full-text