scholarly journals Differences in Responses on the Modified Clinical Test of Sensory Interaction and Balance on Medium Firm and Medium Density Foam in Healthy Controls and Patients with Vestibular Disorders

2020 ◽  
Vol 5 (1) ◽  
pp. 1-8
Author(s):  
Helen S. Cohen ◽  
Haleh Sangi-Haghpeykar
Keyword(s):  
Test Performance ◽  
Clinical Decision Making ◽  
Head Movements ◽  
Clinical Test ◽  
Medium Density ◽  
Foam Density ◽  
Vestibular Disorders ◽  
Trial Duration ◽  
Balance Test ◽  
Eyes Closed

Purpose: To determine whether foam density affects modified Romberg balance test performance. Materials and Methods: Controls and patients with vestibular disorders performed Romberg tests on medium and medium firm foam, with their eyes closed and the head still and moving in yaw and pitch. The trial duration and number of head movements were measured. Results: Subjects aged >60 years performed longer and with more head movements on medium firm foam than on medium foam. Older controls did not differ between medium firm and medium foam. Older patients had higher scores on head-still and head-yaw trials on medium firm foam versus medium foam but pitch trials did not differ. Females, controls, and patients had longer trial durations and more head movements on medium firm foam than on medium density foam; male controls did not differ by foam density. Male patients differed in yaw trials. Conclusion: Foam density affects scores. Clinical decision-making may be adversely affected if the clinician uses foam of a density that is not the same as that of the foam that was used in the studies that developed descriptive statistics, sensitivity, and specificity.

scholarly journals Multivariate Analyses of Balance Test Performance, Vestibular Thresholds, and Age

2017 ◽  
Vol 8 ◽  
Author(s):  
Faisal Karmali ◽  
María Carolina Bermúdez Rey ◽  
Torin K. Clark ◽  
Wei Wang ◽  
Daniel M. Merfeld
Keyword(s):  
Test Performance ◽  
Principal Component ◽  
Vertical Axis ◽  
Balance Test ◽  
Healthy Humans ◽  
Eyes Closed ◽  
Multiple Variable ◽  
Variation Explained ◽  
Romberg Test ◽  
Roll Tilt

We previously published vestibular perceptual thresholds and performance in the Modified Romberg Test of Standing Balance in 105 healthy humans ranging from ages 18 to 80 (1). Self-motion thresholds in the dark included roll tilt about an earth-horizontal axis at 0.2 and 1 Hz, yaw rotation about an earth-vertical axis at 1 Hz, y-translation (interaural/lateral) at 1 Hz, and z-translation (vertical) at 1 Hz. In this study, we focus on multiple variable analyses not reported in the earlier study. Specifically, we investigate correlations (1) among the five thresholds measured and (2) between thresholds, age, and the chance of failing condition 4 of the balance test, which increases vestibular reliance by having subjects stand on foam with eyes closed. We found moderate correlations (0.30–0.51) between vestibular thresholds for different motions, both before and after using our published aging regression to remove age effects. We found that lower or higher thresholds across all threshold measures are an individual trait that account for about 60% of the variation in the population. This can be further distributed into two components with about 20% of the variation explained by aging and 40% of variation explained by a single principal component that includes similar contributions from all threshold measures. When only roll tilt 0.2 Hz thresholds and age were analyzed together, we found that the chance of failing condition 4 depends significantly on both (p = 0.006 and p = 0.013, respectively). An analysis incorporating more variables found that the chance of failing condition 4 depended significantly only on roll tilt 0.2 Hz thresholds (p = 0.046) and not age (p = 0.10), sex nor any of the other four threshold measures, suggesting that some of the age effect might be captured by the fact that vestibular thresholds increase with age. For example, at 60 years of age, the chance of failing is roughly 5% for the lowest roll tilt thresholds in our population, but this increases to 80% for the highest roll tilt thresholds. These findings demonstrate the importance of roll tilt vestibular cues for balance, even in individuals reporting no vestibular symptoms and with no evidence of vestibular dysfunction.

scholarly journals An observational study of balance and proprioception function in patients with spinocerebellar ataxias type 3

2020 ◽  
Author(s):  
Xia-Hua Liu ◽  
Ying Li ◽  
Hao-Ling Xu ◽  
Arif Sikandar ◽  
Wei-Hong Lin ◽  
...  
Keyword(s):  
Postural Control ◽  
Dynamic Balance ◽  
Body Sway ◽  
Static Balance ◽  
Clinical Test ◽  
Spinocerebellar Ataxias ◽  
Balance Test ◽  
Eyes Closed ◽  
Eyes Open ◽  
Type 3

Abstract BackgroundPostural instability is one of the most disabling features of spinocerebellar ataxias type 3 (SCA3) and often leads to falls that reduce mobility and functional capacity. This study aimed to quantitatively analyse static and dynamic balance and proprioception function on postural control in patients with SCA3 using the Pro-kin system and optimise rehabilitation programmes for them.MethodsEight-one clinically diagnosed SCA3 patients (38 women, 43 men; aged 39.00 ± 9.66) and 62 healthy controls were studied and evaluated using the Pro-kin system (PK254P, Tecnobody S.r.l, Dalmine, Italy). The measurements included (1) a static balance test in two visual feedback conditions: eyes open (EO) and eyes closed (EC); (2) a dynamic balance test measuring limits of stability (LOS); and (3) a proprioception function test to obtain proprioceptive measurements on a multiaxial balance evaluator for both right and left lower limbs.ResultsCompared to controls, SCA3 patients showed significantly higher values of all static balance outcome variables with eyes open and eyes closed, implying postural instability. SCA3 patients showed significantly higher values in the standard deviation of body sway along the medio-lateral (ML) axis and in the velocity of body sway along the anterior-posterior (AP) axis. The overall scores and the scores for all eight LOS components were significantly lower in the SCA3 patients than in the controls. The mean values of AP index (API), ML index (MLI), Stability index (SI) and average trace error (ATE) were significantly greater in SCA3 patients compared to HC subjects, while API showed a trend toward higher values.ConclusionsSCA3 patients have a significant postural control disorder, and are likely to fall on the AP plane and prefer performing postural adjustments in the ML direction; a decreased proprioception function in the knee and ankle is also evident. Visual cues and proprioception should be emphasized in balance rehabilitation training. Attention should also be paid to improve muscle strength and range of motion.Trial registrationThe Chinese clinical test registration center. ChiCTR1800020133. Registered 15 december 2018 - Retrospectively registered, http://www.chictr.org.cn/showprojen.aspx?proj=33950

scholarly journals Screening for Vestibular Disorders Using the Modified Clinical Test of Sensory Interaction and Balance and Tandem Walking With Eyes Closed

2019 ◽  
Vol 40 (5) ◽  
pp. 658-665 ◽  
Author(s):  
Helen S. Cohen ◽  
Ajitkumar P. Mulavara ◽  
Jasmine Stitz ◽  
Haleh Sangi-Haghpeykar ◽  
Susan P. Williams ◽  
...  
Keyword(s):  
Clinical Test ◽  
Vestibular Disorders ◽  
Sensory Interaction ◽  
Eyes Closed

The Effect of Sex, Sport Participation, and Concussion History on Baseline Concussion Balance Test Performance in Division-I Collegiate Athletes

Neurology ◽  
2021 ◽  
Vol 98 (1 Supplement 1) ◽  
pp. S19.1-S19
Author(s):  
Carolina Quintana ◽  
Nathan Morelli ◽  
Morgan L. Andrews ◽  
Madison Kelly ◽  
Nicholas Heebner ◽  
...  
Keyword(s):  
Test Performance ◽  
Sport Participation ◽  
Postural Sway ◽  
Collegiate Athletes ◽  
Sports Participation ◽  
Division I ◽  
Balance Performance ◽  
Balance Test ◽  
Eyes Closed ◽  
Concussion History

ObjectiveExplore the effect of baseline characteristics such as sex, sport, and concussion history on the Concussion Balance Test (COBALT) performance in collegiate athletes.BackgroundThe COBALT is a recently developed clinical balance assessment specifically for athletic populations following concussion. The task conditions of the COBALT are designed to challenge sensory integration and reweighting processing underlying postural control. It has been documented that balance performance is influenced by factors such as sex and sport in collegiate athletes.Design/MethodsOne-hundred twenty seven collegiate athletes (77 male, 50 female; age: 19.81 ± 1.39; height: 68.77 ± 5.57 in; mass: 80.98 ± 26.15 kg), who participated in Division-I football, soccer, or cheerleading were included. Participants completed the 4 baseline conditions (Condition 3, 4, 7, 8) of the COBALT. Condition 3 (C3) included a side-to-side headshake with eyes closed. For Condition 4 (C4) the participant stood with hands clasped, elbows extended, and thumbs up while rotating their trunk side-to-side, visually focusing on their thumbs. Conditions 7 (C7) and 8 (C8) repeated C3 and C4 on a foam surface. Two 20-second trials of each condition were completed on a forceplate and the mean angular sway velocity (°/s) were calculated and number of errors were counted. ANOVAs and ANCOVAs were used to assess the potential effects on COBALT performance.ResultsThere were no significant differences in postural sway for any COBALT condition based on sex (p > 0.05). Females demonstrated more errors than males on C7 (p < 0.001). Cheerleaders had more balance errors compared to football athletes for C3 and C7 (p < 0.05) and soccer athletes for C7 (p < 0.05). Concussion history did not have an effect on COBALT performance (p > 0.05).ConclusionsUnderstanding factors that may influence COBALT performance at baseline may enhance concussion evaluation in collegiate athletes with suspected balance deficits following concussion. While concussion history had no effect, sex and sports participation may influence performance and should be considered when interpreting COBALT results post-concussion.

scholarly journals Posturography with head movements in the assessment of balance in chronic unilateral vestibular lesions

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Magdalena Janc ◽  
Mariola Sliwinska-Kowalska ◽  
Piotr Politanski ◽  
Marek Kaminski ◽  
Magdalena Jozefowicz-Korczynska ◽  
...  
Keyword(s):  
High Reliability ◽  
Low Frequency ◽  
Random Order ◽  
Head Movements ◽  
Canal Paresis ◽  
Eyes Closed ◽  
Static Posturography ◽  
Unstable Surface ◽  
Novel Method ◽  
The One

AbstractThe aim of our study was to validate the method of head-shake static posturography (HS-posturography) in healthy individuals and to establish the value of this novel method in the diagnostics of patients with unilateral vestibular lesion (UV). The study included 202 participants divided into two groups, one consisting of 133 patients with canal paresis CP > 19% and one of 69 healthy subjects. Participant was tested according to the standard protocol of static posturography (SP), and with head movements of 0.3 Hz (HS 40), 0.6 Hz (HS 70) in random order controlled by a metronome. HS-posturography revealed a similar repeatability and internal consistency as the standard posturography. In patients with UV, 4th condition revealed higher sensitivity (74%) and specificity (71%) in HS 40 than in the standard posturography (67%, 65% respectively) and HS 70 (54%, 70% respectively). Static posturography and HS- posturography revealed a high reliability of the testing method. The head movements added to static posturography improve the sensitivity and specificity of the method in group with vestibular impairment. The most important test for that purpose seems to be the one on unstable surface with the eyes closed, with low frequency of head movements.

scholarly journals Detection of human elastase isoforms by the ScheBo Pancreatic Elastase 1 Test

2017 ◽  
Vol 312 (6) ◽  
pp. G606-G614 ◽  
Author(s):  
Anna Zsófia Tóth ◽  
András Szabó ◽  
Eszter Hegyi ◽  
Péter Hegyi ◽  
Miklós Sahin-Tóth
Keyword(s):  
Test Performance ◽  
Genetic Variants ◽  
Molecular Targets ◽  
Exocrine Function ◽  
Clinical Test ◽  
Critical Determinant ◽  
Pancreatic Elastase ◽  
Elastase 1 ◽  
Common Genetic Variants ◽  
Pancreatic Elastase 1

Determination of fecal pancreatic elastase content by ELISA is a reliable, noninvasive clinical test for assessing exocrine pancreatic function. Despite the widespread use of commercial tests, their exact molecular targets remain poorly characterized. This study was undertaken to clarify which human pancreatic elastase isoforms are detected by the ScheBo Pancreatic Elastase 1 Stool Test and whether naturally occurring genetic variants influence the performance of this test. Using recombinantly expressed and purified human pancreatic proteinases, we found that the test specifically measured chymotrypsin-like elastases (CELA) 3A and 3B (CELA3A and CELA3B), while CELA2A was not detected. Inactive proelastases, active elastases, and autolyzed forms were detected with identical efficiency. CELA3B elicited approximately four times higher ELISA signal than CELA3A, and we identified Glu154in CELA3B as the critical determinant of detection. Common genetic variants of CELA3A and CELA3B had no effect on test performance, with the exception of the CELA3B variant W79R, which increased detection by 1.4-fold. Finally, none of the human trypsin and chymotrypsin isoforms were detected. We conclude that the ScheBo Pancreatic Elastase 1 Stool Test is specific for human CELA3A and CELA3B, with most of the ELISA signal attributable to CELA3B.NEW & NOTEWORTHY The ScheBo Pancreatic Elastase 1 Stool Test is widely used to assess pancreatic exocrine function, yet its molecular targets have been poorly defined. We demonstrate that, among the human pancreatic proteinases, the test measures the elastase isoform CELA3B and, to a lesser extent, CELA3A. Genetic variants of the human CELA3 isoforms have no significant effect on test performance.

Physical fitness of rhythmic gymnasts depending on age and level of sports achievements

2020 ◽  
Vol 30 (91) ◽  
pp. 29-36
Author(s):  
Katarzyna Sterkowicz-Przybycień ◽  
Paula Fundament
Keyword(s):  
Physical Fitness ◽  
Body Height ◽  
Age Groups ◽  
Standing Position ◽  
Time Duration ◽  
Balance Test ◽  
Eyes Closed ◽  
Fitness Tests ◽  
Rhythmic Gymnasts ◽  
Better Than

Aim. The aim of this study was to compare the indices of physical development, frequency and time duration of training, and the results of physical fitness tests depending on age and level of sports achievements among rhythmic gymnasts. Materials and methods. The study comprised 36 rhythmic gymnasts: Gr1 (n=13, 9.0±1.0 years), Gr2 (n=11, 11.36±0.5 years), Gr3 (n=12, 14.27±0.7 years). After standardised sports interview, the groups with lower level of sports achievements (LSL) (n=20) and higher level of sports achievements (HSL) (n=16) were defined. Measurements of body height and mass were performed. The study participants performed the broad jump test, Unipedal Stance Test with Eyes Open (UPST-EO) and Eyes Closed (EC), and the rhythmic gymnastics specific coordinative test with a hoop. Results. The number of training sessions per week and their duration did not depend on age. The results of the broad jump were significantly different for groups Gr1, Gr2 and Gr3 (F=27.02, p<0.01). The average results for the 3 trials of UPST-EO in Gr2 and Gr3 were better than in Gr1 (F=5.51, p=0.008). The average result of UPST-EC for Gr3 was also significantly better than for Gr1 (W=9.53, p=0.008). The hoop test showed differences for all age groups Gr1<Gr3<Gr2 (F=11.55, p<0.001). HSL athletes were significantly different from LSL in frequency and duration of training, average results from 3 trials of UPST-EO, UPSTEC and the best result of UPST-EC (p<0.05). Conclusions. Differences between groups in physical fitness tests results depended on gymnasts’ age and showed their usefulness in the control of training at a particular stage of sports development. HSL gymnasts predominated over LSL in results of the one-leg standing position postural balance test with eyes opened and closed. The detected differences can be useful for coaches in identifying and developing gymnastic talent.

Vestibular disorders and impaired path integration along a linear trajectory

2000 ◽  
Vol 10 (1) ◽  
pp. 7-15 ◽  
Author(s):  
Helen S. Cohen
Keyword(s):  
Acoustic Neuroma ◽  
Vestibular Disorders ◽  
Vestibular Input ◽  
Active Motion ◽  
Eyes Closed ◽  
Acoustic Neuromas ◽  
Vestibular Information ◽  
Lateral Distance ◽  
Eyes Open ◽  
Straight Ahead

The goal of this study was to determine if people use vestibular information to keep track of their positions while walking through a simple course. Subjects were normals and patients with chronic peripheral vestibulopathies – each of whom were tested once – and patients with acoustic neuromas tested pre- operatively and one and three weeks post-operatively. Subjects walked over a straight course, 7.62 m, with their eyes open and then with their eyes closed. The time needed for task performance, the forward distance subjects walked before veering, and the lateral distance subjects veered from the straight ahead were recorded. The angle of veering was then calculated. Normals were able to perform this task easily with eyes open or closed. With eyes closed pre-operative acoustic neuroma subjects walked significantly shorter distances before veering than normals but did not veer significantly more than normals or take longer than normals to perform the task. Chronic vestibulopathy subjects, by contrast, were significantly impaired compared to normals on all measures. With eyes open within a week after acoustic neuroma resection subjects could perform the task as well as normals. With eyes closed, however, post-operative subjects were impaired compared to their own pre-operative levels, but they had returned to their pre-operative levels at the second post-operative test. Ataxia was only weakly correlated to any measures and tumor size was not related to performance. These findings support the hypothesis that vestibular input is used for spatial orientation during active motion.

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