Prolapse Surgery: What Kind of Antibiotic Prophylaxis Is Necessary?

2021 ◽  
pp. 1-6
Author(s):  
Ester Illiano ◽  
Francesco Trama ◽  
Felice Crocetto ◽  
Gianluigi Califano ◽  
Achille Aveta ◽  
...  
Keyword(s):  
Single Dose ◽  
Antibiotic Prophylaxis ◽  
Laparoscopic Approach ◽  
Prolapse Surgery ◽  
Postoperative Treatment ◽  
Vaginal Route ◽  
Group A ◽  
Vaginal Prolapse Surgery ◽  
Tract Infections ◽  
Discharge Protocol

<b><i>Introduction:</i></b> The aim of this study was to assess whether antibiotic prophylaxis or therapy is sufficient for laparoscopic or vaginal prolapse surgery with mesh. <b><i>Methods:</i></b> This is a single-center prospective study. The study was divided into 3 groups. Protocol A: metronidazole (15 mg/kg) and piperacillin-tazobactam (2 g) 1 h before surgery and, for postoperative treatment, gentamycin (160 mg) 1 h before surgery in a single dose. Metronidazole and piperacillin-tazobactam were administered until hospital discharge. Protocol B: gentamycin and piperacillin-tazobactam in the same manner as group A. Protocol C: clindamycin (600 mg) and gentamicin (160 mg) 1 h before surgery in a single dose. <b><i>Results:</i></b> We included 87 consecutive patients who underwent prolapse surgery involving mesh prostheses: 57 by the laparoscopic approach and 30 by the vaginal route. Of these, 30 patients were included in protocol A, 30 in protocol B, and 27 in protocol C. There were no statistically significant differences among the 3 protocols regarding any postoperative complications, except for urinary tract infections that were more in the vaginal approach than in the laparoscopic route, in protocol A (<i>p</i> = 0.002). <b><i>Conclusions:</i></b> One-shot prophylaxis can be successfully used in prolapse surgery regardless of the surgical approach.

scholarly journals Genital Prolapse Surgery: What Options Do We Have in the Age of Mesh Issues?

2021 ◽  
Vol 10 (2) ◽  
pp. 267
Author(s):  
Guenter K. Noé
Keyword(s):  
Laparoscopic Surgery ◽  
Laparoscopic Approach ◽  
Vaginal Surgery ◽  
Genital Prolapse ◽  
Study Data ◽  
Prolapse Surgery ◽  
Autologous Tissue ◽  
Laparoscopic Procedures ◽  
Report Data ◽  
Vaginal Prolapse Surgery

Here, we describe the current laparoscopic procedures for prolapse surgery and report data based on the application of these procedures. We also evaluate current approaches in vaginal prolapse surgery. Debates concerning the use of meshes have seriously affected vaginal surgery and threaten to influence reconstructive laparoscopic surgery as well. We describe the option of using autologous tissue in combination with the laparoscopic approach. Study data and problematic issues concerning the existing techniques are highlighted, and future options addressed.

scholarly journals Role of phytotherapy associated with antibiotic prophylaxis in female patients with recurrent urinary tract infections

2013 ◽  
Vol 85 (4) ◽  
pp. 197 ◽  
Author(s):  
Emanuela Frumenzio ◽  
Daniele Maglia ◽  
Eleonora Salvini ◽  
Silvia Giovannozzi ◽  
Manuel Di Biase ◽  
...  
Keyword(s):  
Urinary Tract ◽  
Antibiotic Prophylaxis ◽  
Urinary Tract Infections ◽  
Female Patients ◽  
Recurrent Urinary Tract Infections ◽  
Long Term Follow Up ◽  
Group A ◽  
Group B ◽  
Tract Infections

Objective: Aim of this study is to evaluate the efficacy of a phytotherapic which includes Solidago, Orthosiphon and Birch extract (Cistimev®) in association with antibiotic prophylaxis in female patients affected by recurrent urinary tract infections (UTIr). Materials and methods: Patients affected by UTIr older than 18 years started a 3-months antibiotic prophylaxis (Prulifloxacin 600 mg, 1 cps/week or Phosphomicyn 1 cachet/week) according to antibiogram after urine culture. The patients were divided in 2 groups: Group A: antibiotic prophylaxis plus phytotherapy (1 cps/die for 3 months) and Group B: antibiotic prophylaxis alone. Results: 164 consecutive patients were studied: 107 were included in group A (mean age 59 ± 17.3 years) and 57 (mean age 61 ± 15.7) in group B. During the treatment period the relapse frequencies between the two groups were not significantly different (p = 0.854): 12/107 (11.21%) patients interrupted the treatment for UTIr in group A and 6/57 (10.52%) in group B. In the long term follow-up the relapse UTI risk was significant different in the two groups with a relapse risk 2.5 greater in group B than in group A (p &lt; 0.0001). Conclusion: Our study demonstrated that in female patients affected by recurrent UTI, the association between antibiotic prophylaxis and of a phytotherapic which includes Solidago, Orthosiphon and Birch extract reduced the number of UTI in the 12 months following the end of prophylaxis and obtained a longer relapsing time, greatly improving the quality of life of the patients.

Antimicrobial prophylaxis in noninstrumented spine surgery: a prospective study to determine efficacy and drawbacks

2021 ◽  
pp. 1-10
Author(s):  
Aymeric Amelot ◽  
Maximilien Riche ◽  
Samuel Latreille ◽  
Vincent Degos ◽  
Alexandre Carpentier ◽  
...  
Keyword(s):  
Risk Factors ◽  
Single Dose ◽  
Prospective Study ◽  
Antibiotic Prophylaxis ◽  
Spine Surgery ◽  
Surgical Site Infections ◽  
Csf Leak ◽  
Resistant Bacteria ◽  
Group A ◽  
Group B

OBJECTIVE The authors sought to evaluate the roles of perioperative antibiotic prophylaxis in noninstrumented spine surgery (NISS), both in postoperative infections and the impact on the selection of resistant bacteria. To the authors’ knowledge, only one prospective study recommending preoperative intravenous (IV) antibiotics for prophylaxis has been published previously. METHODS Two successive prospective IV antibiotic prophylaxis protocols were used: from 2011 to 2013 (group A: no prophylactic antibiotic) and from 2014 to 2016 (group B: prophylactic cefazolin). Patient infection rates, infection risk factors, and bacteriological status were determined. RESULTS In total, 2250 patients (1031 in group A and 1219 in group B) were followed for at least 1 year. The authors identified 72 surgical site infections, 51 in group A (4.9%) and 21 in group B (1.7%) (p < 0.0001). A multiple logistic regression hazard model identified male sex (HR 2.028, 95% CI 1.173–3.509; p = 0.011), cervical laminectomy (HR 2.078, 95% CI 1.147–3.762; p = 0.016), and postoperative CSF leak (HR 43.782, 95% CI 10.9–189.9; p < 0.0001) as independent predictive risk factors of infection. In addition, preoperative antibiotic prophylaxis was the only independent favorable factor (HR 0.283, 95% CI 0.164–0.488; p < 0.0001) that significantly reduced infections for NISS. Of 97 bacterial infections, cefazolin-resistant bacteria were identified in 26 (26.8%), with significantly more in group B (40%) than in group A (20.9%) (p = 0.02). CONCLUSIONS A single dose of preoperative cefazolin is effective and mandatory in preventing surgical site infections in NISS. Single-dose antibiotic prophylaxis has an immediate impact on cutaneous flora by increasing cefazolin-resistant bacteria.

scholarly journals COMPARISON OF DURATION OF SURGERY AFTER SINGLE DOSE ANTIBIOTIC PROPHYLAXIS AT DIFFERENT TIME INTERVAL IN PATIENTS UNDERGOING ELECTIVE LAPAROSCOPIC CHOLECYSTECTOMY

2021 ◽  
Vol 5 (6) ◽  
Author(s):  
Suneet Katoch ◽  
Mukesh Kumar Jamwal ◽  
Sanjay Kumar
Keyword(s):  
Laparoscopic Cholecystectomy ◽  
Single Dose ◽  
Antibiotic Prophylaxis ◽  
Time Interval ◽  
Duration Of Surgery ◽  
Group A ◽  
Elective Laparoscopic Cholecystectomy ◽  
Group B

Background: In this study we compare the duration of surgery   after single dose antibiotic prophylaxis at different time interval in patients undergoing elective laparoscopic cholecystectomy Methods: The present study was conducted at Department of Surgery, Dr RPGMC Kangra at Tanda. The 50 patients admitted for elective laparoscopic cholecystectomy, aging less than 75  years of both the genders were included Results: In the present study, mean duration of surgery of the patients in group A and group B was 59.80±15.91 minutes and 63.12±12.50 minutes Conclusion: Our study we concluded that mean duration of surgery difference was not statistically significant between group A and group B. Keywords:  Duration of surgery, Cholelithiasis,  Cholecystectomy.

scholarly journals TO COMPARE THE DURATION OF SURGERY IN SINGLE DOSE INTRAVENOUS ANTIBIOTIC PROPHYLAXIS OVER NO ANTIBIOTIC PROPHYLAXIS IN THE PREVENTION OF WOUND INFECTION FOLLOWING LICHTENSTEIN TENSION FREE INGUINAL HERNIOPLASTY

2021 ◽  
Vol 5 (6) ◽  
Author(s):  
Prteet Negi ◽  
Priyanka Thakur ◽  
Ramesh Bharti ◽  
Amar Verma ◽  
Rajesh Sharma ◽  
...  
Keyword(s):  
Single Dose ◽  
Antibiotic Prophylaxis ◽  
Wound Infection ◽  
Inguinal Hernioplasty ◽  
Intravenous Antibiotic ◽  
Duration Of Surgery ◽  
Antibiotic Group ◽  
Group A ◽  
The Mean ◽  
Group B

Background: We conducted a study to compare the duration of surgery in single dose intravenous antibiotic prophylaxis over no antibiotic prophylaxis in the prevention of wound infection following Lichtenstein tension free inguinal hernioplasty Methods: This prospective study was conducted in the Department of Surgery, Dr. Rajendra Prasad Government Medical College Kangra at Tanda from May 2018 to December 2019after being approved by institutional protocol review committe and ethics committee.50 patients were included in the study.These patients were randomised into two groups i.e. Group A (Antibiotic Group) and Group B (Non-antibiotic Group). Results: The mean duration of surgery in Antibiotic group (Group-A) was 56.6±15.66 minutes whereas it was 50.2±9.62 minutes in Non-antibiotic group (Group-B). The mean duration of surgery was more in Antibiotic group (Group-A) as compared to Non-antibiotic group (Group-B), however the difference was not statistically significant (p= 0.088).    Conclusion: In our study, we concluded that statistically insignificant difference was found in the duration of surgery in Antibiotic and Non-antibiotic Group Keywords: Duration of surgery, Antibiotic, Pre-operative

scholarly journals Comparison of single dose versus multiple doses of antibiotic prophylaxis for prevention of surgical site infection

2021 ◽  
Vol 9 (1) ◽  
pp. 129
Author(s):  
Swapan Das ◽  
Rajib Kundu ◽  
Bani Prasad Chattopadhyay
Keyword(s):  
Single Dose ◽  
Surgical Site Infection ◽  
Antibiotic Prophylaxis ◽  
Multiple Dose ◽  
Cost Effective ◽  
Site Infection ◽  
Significant Difference ◽  
Group A ◽  
Group B ◽  
Clean Contaminated

Background: Surgical site infection is a common problem following general surgical procedures. Despite major improvement in antibiotics, improved antiseptic measures SSI continues to present a big challenge. In this study we will compare single dose versus multiple dose antibiotic prophylaxis for prevention of SSI in clean and clean contaminated surgical wound.Methods: This is an institution based prospective, comparative study, with total 60 patients as study population. Clinical finding, wound swab culture and routine haematological reports were taken as study variables. Patients receiving single dose antibiotic and multiple dose antibiotic were included in ‘Group A’ and ‘Group B’ respectively. The surgical sites were examined from post-operative days 3 to 8 for signs of infection.Results: In This study, 46.7% patients were female, and 53.3% patients were male. In Group-A, patients having post operative fever, tachycardia and leucocytosis were 16.7%, 13.3% and 20.0% respectively. 6.7% patients had purulent and 10.0% patients had seropurulent discharge from wound. In Group-B, patients having post operative fever, tachycardia, and leucocytosis were 13.3%, 16.7% and 13.3% respectively. 6.7% patients had purulent and seropurulent discharge from wound. There is no statistically significant difference between two groups regarding post operative fever, tachycardia, leucocytosis and wound discharge.Conclusions: There is no significant difference between single dose and multiple dose antibiotic prophylaxis to prevent SSI in patients for elective clean and clean contaminated surgery however single dose is more cost effective.

A Single Dose Antibiotic Prophylaxis in Clean Surgery:-Our Experience

2011 ◽  
Vol 2 (2) ◽  
pp. 122-123
Author(s):  
Dr.Chakane Milind ◽  
◽  
Dr.Snehal Purandare
Keyword(s):  
Single Dose ◽  
Antibiotic Prophylaxis
Sign in / Sign up

Export Citation Format

Share Document