Effect of surface modified liposomes on the aggregation of platelets and tumor cells

2005 ◽  
Author(s):  
Claudia Keil ◽  
Reiner Zeisig ◽  
Iduna Fichtner
Keyword(s):  
Tumor Cells ◽  
Surface Modified ◽  
Aggregation Of Platelets ◽  
Effect Of Surface

Combined antitumor effect of surface-modified superparamagnetic maghemite nanoparticles and a vitamin E derivative on experimental Walker-256 mammary gland carcinosarcoma

2019 ◽  
Vol 471 ◽  
pp. 381-387 ◽  
Author(s):  
Beata A. Zasońska ◽  
Vitaliy Igorovych Pustovyy ◽  
Andriy Valeriyovich Babinskiy ◽  
Olga Mikhailovna Palyvoda ◽  
Vasyl Fedorovich Chekhun ◽  
...  
Keyword(s):  
Mammary Gland ◽  
Vitamin E ◽  
Antitumor Effect ◽  
Maghemite Nanoparticles ◽  
Walker 256 ◽  
Surface Modified ◽  
Effect Of Surface

scholarly journals Effect of surface-modified MgO nanoparticles on intragranular ferrite nucleated on inclusions in low-alloy steel

2019 ◽  
Vol 182 ◽  
pp. 108004 ◽  
Author(s):  
Hao Guo ◽  
Shufeng Yang ◽  
Yanling Zhang ◽  
Jingshe Li ◽  
Tiantian Wang
Keyword(s):  
Alloy Steel ◽  
Low Alloy Steel ◽  
Mgo Nanoparticles ◽  
Intragranular Ferrite ◽  
Surface Modified ◽  
Effect Of Surface

scholarly journals Ultrastructural Study of Platelet Aggregation by Mouse 15091A Tumor Cells

1977 ◽  
Author(s):  
G.J. Stewart ◽  
R.A. Kuprionas ◽  
G.J. Gasic ◽  
J. Catalfamo ◽  
G.P. Gasic
Keyword(s):  
Platelet Aggregation ◽  
Tumor Cells ◽  
Lysosomal Enzymes ◽  
Culture Medium ◽  
Open Channel ◽  
Channel System ◽  
Transmission Electron ◽  
Spherical Vesicles ◽  
Aggregation Of Platelets ◽  
Soluble Material

Most tumor cells cause aggregation of platelets in heparinized plasma via material shed into culture medium. In this study we investigated the events by transmission electron microscopy. Freshly washed cells were covered with closely spaced microvilli, many of which pinched off during 1 hour of incubation at 37°C. Both cells and shed microvilli were membrane enclosed. Shed microvilli became spherical vesicles containing cytoplasm. Platelets aggregated when stirred with incubated tumor cells or shed material. The aggregates were composed of platelets that showed pseudopod formation, centralization of granules and increase in the open channel system. Platelets around the periphery of aggregates had bulbous portions free of granules (ballooning) but many granules remained in platelets in the interior of aggregates suggesting that release of lysosomal enzymes may have been somewhat limited. Aggregates resembled those induced by ADP rather than by thrombin. Tumor cells were not incorporated into the aggregates. Vesicles were not selectively associated with platelets prior to or during aggregation. While some vesicles were incorporated into aggregates, it appeared that this was a consequence rather than the cause of aggregation. Therefore, vesicles may have produced soluble material that induced platelet aggregation.

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