scholarly journals Hospital acquired infections in a private paediatric hospital in Kenya: a retrospective cross-sectional study

2022 ◽  
Vol 41 ◽  
Author(s):  
Rohini Kalagouda ◽  
Beatrice Kabera ◽  
Charles Kiilu Muia ◽  
Boni Maxime Ale
2017 ◽  
Vol 4 (3) ◽  
pp. 933 ◽  
Author(s):  
Kiran Kartheek ◽  
Baliga B. S. ◽  
. Subodhshetty ◽  
Prasanna Mithra ◽  
Charu Yadav

Background: In developing countries sepsis is a major etiological factor contributing to 60-80 % of annual mortality. SIRS/sepsis rates are high among children admitted to hospitals particularly in intensive care units. Oxidative stress plays important role in etio-pathogenesis of SIRS/sepsis. Nutrients with antioxidant activity enhance immune system there by decreasing severity of SIRS/sepsis. Estimation of such nutrient levels might establish relationship with oxidative stress in children with SIRS/sepsis.Methods:A hospital based cross-sectional study was done on consecutive samples of 96 children diagnosed with SIRS/sepsis. Serum copper, iron zinc, magnesium levels of children diagnosed with sepsis/SIRS included in the study were estimated, data were represented as median with inter quartile range and proportions. Mann Whitney u test and Karl Pearson’s correlation tests were used to see correlation between clinical paramaters.Results: Zinc and magnesium deficiency were seen in 68.8% and 59.4% children with SIRS/sepsis. Median serum magnesium levels were 1.24mg/dL in children with illness <1 week and 1.51mg/dL with illness >1week duration prior to hospitalization (p=0.017). Hospital acquired infections were higher with zinc (P=0.001) and copper deficiency(P=0.002). Zinc deficiency correlated with need for longer hospitalization (P= 0.017).  Mortality due to SIRS/sepsis increased as number of nutrient deficiencies increased (P =0.009).Conclusions:Significant number of children with SIRS/sepsis had nutrient deficiencies. These deficiencies correlated significantly with duration of illness prior to hospitalization. Children with nutrient deficiency had higher incidence of hospital acquired infections. Children with normal nutrient levels have decreased length of hospitalization. Children with multiple nutrient deficiency had higher risk of death. 


2014 ◽  
Vol 4 (2) ◽  
pp. 49-52 ◽  
Author(s):  
MH Zaman ◽  
S Ferdouse

Objectives: To find out the proportion, to determine the average length of stay at hospital and to estimate the cost of treatment for hospital-acquired infections in a tertiary level hospital of Rangpur City. Materials and Methods: This descriptive type of cross sectional study was conducted on purposively selected 200 admitted patients in a tertiary level hospital. Among them 100 were HAI patients and 100 were non HAL Data were collected through duly pretested interviewer administered questionnaire and observation checklist. Place and period of study: This study was conducted in Rangpur Medical College Hospital (RpMCH), Rangpur from January to June2011. Results: In this cross sectional study the highest percentage of HAI (42%) belonged to the surgery ward and the lowest percentage (19.%) belonged to medicine ward of the study hospital. According to the type of infections the surgical wound infection was found on the top (23%) and the cannula-associated infection at the bottom (5%) of the list. Respondents of both the polar age groups (<21 years and > 60 years) were found to be equally (27%) affected by HAI. Occurrence of HAI was found higher (57%) among the female respondents than their male (43%) counterparts. Highest number (48%) of HAI and lowest number (14%) of non- HAI patients were found to be visited by maximum number (?5) of visitors. Among the respondents who developed HAI, 42% had to stay at hospital for longest duration (21-25 days) but only 13% of their non- HAI counterparts had to stay for same duration. Among HAI patients 26% had to spend highest amount of money (Tk.20,0011- 25,0001-) but among non- HAI patients only 10% had to spend same amount of money for their treatment purpose. Conclusion: It has been revealed from this study that the occurrence of HAI was found higher among the patients with maximum number of visitors. Average length of hospital stay and cost of treatment of HAI patients were found higher than those of their non-HAI counterparts. DOI: http://dx.doi.org/10.3329/bjdre.v4i2.20247 Bangladesh Journal of Dental Research and Education Vol.4(2) 2014: 49-52


2021 ◽  
Vol 21 (2) ◽  
pp. 513-522
Author(s):  
Meseret Mitiku Gemechu ◽  
Tesfaye Assefa Tadesse ◽  
Getahun Negash Takele ◽  
Fithamlak Solomon Bisetegn ◽  
Yonas Alem Gesese ◽  
...  

Background: Hospital acquired infections (HAIs) are one of the global concerns in resource limited settings. The aim of the study was to determine bacteria profile and their antimicrobial susceptibility patterns among patients admitted at surgical and medical wards. Methods: A hospital based cross-sectional study was conducted from November 2016 to July 2017 in MaddaWalabu Uni- versity Goba Referral Hospital. Urine and wound swabs were processed and standard disk diffusion test was done to assess susceptibility pattern. Association among variables was determined by Chi-square test. Results: Among 207 patients enrolled, 24.6% developed HAI, of which, 62.7% and 37.3% were from surgical and medical wards, respectively. The male to female ratio was 1.5:1. The age ranged from 19 to 74 years with a mean of 41.65(±16.48) years. A total 62 bacteria were isolated in which majority of the isolates were gram negative bacteria. Most isolates were re- sistance to most of the antibiotics tested but sensitive to Ceftriaxone, Norfloxacin and Ciprofloxacin. Conclusion: Due to the presence of high level drug resistant bacteria, empirical treatment to HAI may not be effective. Therefore, treatment should be based on the result of culture and sensitivity. Keywords: Antimicrobial susceptibility patterns; bacterial profile; hospital acquired infections.


Author(s):  
Martin Mumuni Danaah Malick ◽  
Edem Yao Akpa ◽  
Peter Paul Bamaalabong

Background: Hospital Acquired Infections (HAIs) place a significant economic burden on the healthcare system. Infection control practices are important in minimizing healthcare associated infections. However, low compliance with Universal and Standard Precautions has been reported in a number of studies. The Centre for Disease Control and Prevention (CDC) developed baseline definitions for HAIs that were republished in 2004 and has defined HAIs as those that develop during hospitalization but are neither present nor incubating upon the patient’s admission to the hospital; generally, these infections occur between 48 to 72 hours after admission and within 10 days after hospital discharge. this study aimed at unveiling the level of knowledge, attitude and practices on infection prevention control in the operating theatres by anaesthesia practitioners at TTH. Materials and Methods: A cross-sectional study design was employed. A mixed-method approach was used for data collection which includes a structured questionnaire carried out via face to face interview and observation. Results: The study showed that 100% of the respondents have knowledge on hospital acquired infection control in the theatre in one way or the other whereas attitude and practices toward hospital infection control in the operating theatres are undesirable in some specific areas of infection control such as wearing of sterile gowns and goggle. As high as 80.6% and 69.4% do not wear goggle and gowns respectively whilst performing regional anaesthesia.  Conclusions:  This study demonstrated that anaesthetists at TTH have reported sub-optimal levels of compliance i.e. attitude and practices with selective infection control. The study further demonstrated that discrepancies exist between anaesthetists’ attitudes towards a guideline as well as their actual practice.


2020 ◽  
Vol 14 (12) ◽  
pp. 1402-1409
Author(s):  
Antonio M Quispe ◽  
Gabriela Soza ◽  
Maria J Pons

Introduction: This study aimed to assess the prevalence of multidrug resistance (MDR) and its associated factors among pregnant Peruvian women with bacteremia. Methodology: In an 18-month cross-sectional study, all pregnant women were routinely tested with a presumptive diagnosis of sepsis admitted to the largest reference maternity hospital (Instituto Nacional Materno Perinatal) in Lima, Peru for bacteremia. Every isolate was tested for antimicrobial susceptibility as defined by the Institute of Clinical and Laboratory Standards (CLSI). Additionally, associated factors were assessed with MDR and the number of resistant antimicrobial categories using robust Poisson regression models with link log, especially focused on its association with age and bacterial families or species. Results: A total of 236 blood cultures of pregnant women (33.4 ± 11.4 years old) was analyzed. The prevalence of MDR was 70% (95% confidence interval [CI]: 64%–76%). The main etiological agent was Escherichia coli (65%), showing an MDR rate of 74% (68%–81%). Overall, we observed that the MDR rate was associated with Enterobacteriales (adjusted prevalence rate, (aPR) = 1.29; 95% CI: 1.03–1.61) and age 35 or older (PR = 1.18; 95% CI: 1.01–1.39). However, the number of resistant antimicrobial categories was associated with Enterobacteriales (aPR = 1.44; 95% CI: 1.25–1.67) and hospital-acquired infections (PR = 0.81; 95% CI: 1.01–1.39). Conclusions: The prevalence of MDR among pregnant women with sepsis was alarmingly high, being even higher among women age 35 or older and among those with hospital-acquired infections.


2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Imtiaz Ahmad ◽  
Wasil Khan ◽  
Aleem ur Rashid ◽  
Samiullah , ◽  
Abdul Ahad ◽  
...  

Background: Pseudomonas aeruginosa is the most troublesome and feared pathogen in medical field. It is the sixth mostcommon cause of hospital-acquired infections and the cause of ventilator-associated pneumonia. The most common multidrugresistantgram-negative pathogen in Ventilated Assisted Patient. In our study in 100 patients culture and sensitivity report only 46%were sensitive to oral treatment while 54% of the pseudomonas were resistant to ciprofloxacin and 34% sensitive and 66%resistant to levofloxacin.Objective: To find out resistance of pseudomonas to oral medication.Material and Methods: A cross-sectional study, conducted in Saidu Group of Teaching Hospital from January 2018 to July 2019. ).100 patient samples (tracheal aspirate, bronchial washing, sputum, pus, urine and blood) were cultured for pseudomonas and itssensitivity to oral medication ciprofloxacin and levofloxacin was recorded.Results: Sensitivity to 46% were samples was observed to oral treatment while 54% of the pseudomonas were resistant tociprofloxacin and 34% sensitive and 66% resistant to levofloxacin respectively.Conclusion: It was found that 54% pseudomonas were resistant to Ciprofloxacin and 66% resistant to levofloxacin. So we shouldalways consider for combination therapy.


2021 ◽  
Author(s):  
MHD Bahaa Aldin Alhaffar ◽  
Khattab Mustafa ◽  
Samira Alsabbagh ◽  
Ola Alhaffar ◽  
Ameer Kakaje

Abstract Background:Since 2011, Syria has been facing a conflict that impacted all aspects of life. Haematological malignancies are mainly treated with chemotherapy which can further harm oral health. This study evaluates oral health of children with haematological malignancies and on chemotherapy in Syria.Methods: This is a cross-sectional study of (40) patients from the major paediatric hospital in Damascus. Decayed, Missing, Filled Teeth (DMFT) and Oral Assessment Guide (OAG) indices were used to evaluate oral health. Data about cancer was collected from medical records. Results: Patients aged between 3-14 years. Three types of paediatric cancer were included; acute lymphoblastic leukaemia (ALL) 52.2%, Hodgkin’s Lymphoma (HL) 27.5%, and Burkitt Lymphoma (BL) 20%. Average DMFT was (6.7 ± 3.2) and average OAG index was (10.8 ± 1.7). DMFT was significantly correlated with OAG (r=0.021). In patients undergoing chemotherapy, better DMFT and OAG indices were reported in males who had cancer for shorter periods, had higher frequency of toothbrushing, or/and were helped while toothbrushing. However, age and cancer type did not significantly affect DMFT and OAG.Conclusion: Children undergoing chemotherapy in Syria had worse oral health and pain compared to other children from the same age in similar studies. More attention should be given to these patients in order to improve their overall health and their quality of life especially during the ongoing conflict.


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