scholarly journals Adenoviral Transfer of Endothelial Nitric Oxide Synthase Attenuates Lesion Formation in a Novel Murine Model of Postangioplasty Restenosis

2004 ◽  
Vol 24 (2) ◽  
pp. 357-362 ◽  
Author(s):  
Jan H. von der Thüsen ◽  
Madelon L. Fekkes ◽  
Robert Passier ◽  
A.J. van Zonneveld ◽  
V. Mainfroid ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Nitric Oxide Synthase ◽  
Murine Model ◽  
Endothelial Nitric Oxide Synthase ◽  
Lesion Formation ◽  
Adenoviral Transfer ◽  
Oxide Synthase ◽  
Endothelial Nitric Oxide

The effect of overexpression of endothelial nitric oxide synthase on eosinophilic lung inflammation in a murine model

2006 ◽  
Vol 6 (7) ◽  
pp. 1040-1052 ◽  
Author(s):  
Kazuyuki Kobayashi ◽  
Yoshihiro Nishimura ◽  
Tomoya Yamashita ◽  
Teruaki Nishiuma ◽  
Miyako Satouchi ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Nitric Oxide Synthase ◽  
Murine Model ◽  
Endothelial Nitric Oxide Synthase ◽  
Lung Inflammation ◽  
Oxide Synthase ◽  
Endothelial Nitric Oxide

Localization of endothelial nitric oxide synthase in the normal and failing human atrial myocardium

1996 ◽  
Vol 54 ◽  
pp. 786-787
Author(s):  
Chi-Ming Wei ◽  
Margarita Bracamonte ◽  
Shi-Wen Jiang ◽  
Richard C. Daly ◽  
Christopher G.A. McGregor ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Heart Failure ◽  
Nitric Oxide Synthase ◽  
Endothelial Nitric Oxide Synthase ◽  
Cardiac Tissues ◽  
Mammalian Tissues ◽  
End Stage Heart Failure ◽  
End Stage ◽  
Oxide Synthase ◽  
Endothelial Nitric Oxide

Nitric oxide (NO) is a potent endothelium-derived relaxing factor which also may modulate cardiomyocyte inotropism and growth via increasing cGMP. While endothelial nitric oxide synthase (eNOS) isoforms have been detected in non-human mammalian tissues, expression and localization of eNOS in the normal and failing human myocardium are poorly defined. Therefore, the present study was designed to investigate eNOS in human cardiac tissues in the presence and absence of congestive heart failure (CHF).Normal and failing atrial tissue were obtained from six cardiac donors and six end-stage heart failure patients undergoing primary cardiac transplantation. ENOS protein expression and localization was investigated utilizing Western blot analysis and immunohistochemical staining with the polyclonal rabbit antibody to eNOS (Transduction Laboratories, Lexington, Kentucky).

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