Sex Differences in Perioperative and Long-term Cardiac Event–Free Survival in Vascular Surgery Patients

Circulation ◽  
1995 ◽  
Vol 91 (4) ◽  
pp. 1044-1051 ◽  
Author(s):  
Robert C. Hendel ◽  
Ming Hui Chen ◽  
Gilbert J. L’Italien ◽  
John B. Newell ◽  
Sumita D. Paul ◽  
...  
Keyword(s):  
Sex Differences ◽  
Vascular Surgery ◽  
Cardiac Event ◽  
Event Free Survival ◽  
Free Survival

scholarly journals Sex differences in long-term outcomes of patients with percutaneous coronary intervention: the Armenian experience

2013 ◽  
Vol 1 (2) ◽  
pp. 17
Author(s):  
Yeva Sahakyan ◽  
Michael E. Thompson ◽  
Lusine Abrahamyan
Keyword(s):  
Percutaneous Coronary Intervention ◽  
Sex Differences ◽  
Coronary Intervention ◽  
Diabetic Patients ◽  
Event Free Survival ◽  
Free Survival ◽  
Cerebrovascular Events ◽  
Percutaneous Coronary

The present study aimed at assessing sex differences in perioperative characteristics and 3-year event-free survival from major adverse cardiac and cerebrovascular events (MACCE) in patients with percutaneous coronary intervention (PCI) in Armenia. The study utilized an observational, retrospective cohort design enrolling patients who underwent PCI from 2006 to 2008 at a single center in Yerevan, Armenia. Major adverse cardiac and cerebrovascular events included all-cause mortality, myocardial infarction (MI), repeat revascularization, or stroke/transient ischemic attack. Among 485 participants included in the analysis, 419 (86%) were men. Women were older, more hypertensive, more obese, and had significantly higher rates of diabetes. At the end of follow-up, the incidence of MACCE was 37% for men and 33% for women (P=0.9). Based on the results from the adjusted Cox proportional hazards model, the independent predictors of MACCE included acute MI [hazard ratio (HR)=1.43, 95% confidence interval (CI): 1.02-2.00], arrhythmia (HR=1.64, 95% CI: 1.07-2.50), sex (HR=2.46, 95% CI: 1.08- 5.61), diabetes (HR=5.65, 95% CI: 2.14-14.95), and the interaction between sex and diabetes (HR=0.16; 95% CI: 0.05-0.47). Among diabetic patients, men had better event-free survival from MACCE (HR=0.40, 95% CI: 0.19-0.85) than women, whereas in patients without diabetes men had worse outcomes than women (95% CI: 1.08-5.62). In Armenia, the baseline profile of women undergoing PCI differed considerably from that of men. In patients with diabetes, women had worse outcomes at long-term follow-up, while the opposite was noted in patients without diabetes.

scholarly journals OP0146 LONG TERM OUTCOME AND PROGNOSIS FACTORS OF ISOLATED AORTITIS

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 93.1-93
Author(s):  
Y. Ferfar ◽  
S. Morinet ◽  
O. Espitia ◽  
C. Agard ◽  
M. Vautier ◽  
...  
Keyword(s):  
Multivariate Analysis ◽  
Giant Cell Arteritis ◽  
Takayasu Arteritis ◽  
Vascular Complications ◽  
Event Free Survival ◽  
Prognosis Factors ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Free Survival

Background:Aortitis is a group of disorders characterized by the inflammation of the aorta. The most common causes of aortitis are the large-vessel vasculitis i.e. giant cell arteritis (GCA) and Takayasu arteritis (TA). However, aortitis may be isolated. Because of the wide variation in the course of aortitis, predicting outcome is challenging. The optimal management strategy of isolated aortitis (IA) is still unclear as IA is poorly defined, with data consisting of small retrospective and case control studies.Objectives:To assess the long-term outcome and prognosis factors for vascular complications in patients with isolated aortitis.Methods:Retrospective multicenter study of 353 patients with non-infectious aortitis including 136 giant cell arteritis (GCA), 96 Takayasu arteritis (TA) and 73 isolated aortitis (IA). Factors associated with event-free survival, vascular event-free survival and revascularization-free survival were assessed. Risk factors for vascular complications were identified in multivariate analysis.Results:After a median follow up of 52 months, vascular complications were observed in 32.3 %, revascularization in 30 % and death in 7.6%. The 5-year cumulative incidence of vascular complications was 58% (41; 71), 20% (13; 29), and 19 % (11; 28) in IA, GCA and TA, respectively. In multivariate analysis, IA [HR, 1.85 (1.19 to 2.88), p=0.017] and male gender [1.77 (1.26 to 2.49), p<0.0001] were independently associated with vascular events. The 5-year surgery-free survival was 45% (31; 65), 71% (62; 81) and 76% (68; 86) in IA, TA and GCA, respectively.Conclusion:IA has a worse vascular prognosis than GCA and TA. Sixty percent of IA patients will experience a vascular complication within 5 years from diagnosis.Disclosure of Interests:None declared

scholarly journals CRT-720 Mitral Balloon Valvuloplasty Long-Term Follow-Up of Single Balloon Versus Inoue Balloon Techniques. Independent Predictors of Survival and Event Free Survival

2014 ◽  
Vol 7 (2) ◽  
pp. S57
Author(s):  
Edison Sandoval Peixoto Peixoto ◽  
Ivana Picone Borges ◽  
Rodrigo Trajano Sandoval Peixoto ◽  
Ricardo Trajano Sandoval Peixoto
Keyword(s):  
Balloon Valvuloplasty ◽  
Event Free Survival ◽  
Free Survival ◽  
Long Term Follow Up ◽  
Single Balloon ◽  
Inoue Balloon

scholarly journals Sex Differences in the Association Between Inflammation and Event-Free Survival in Patients With Heart Failure

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Zyad T. Saleh ◽  
Ahmad T. Alraoush ◽  
Ahmad A. Aqel ◽  
Tagreed O. Shawashi ◽  
Misook Chung ◽  
...  
Keyword(s):  
Heart Failure ◽  
Sex Differences ◽  
Event Free Survival ◽  
Free Survival ◽  
Patients With Heart Failure

Racial differences in dietary antioxidant intake and cardiac event-free survival in patients with heart failure

2018 ◽  
Vol 17 (4) ◽  
pp. 305-313 ◽  
Author(s):  
Jia-Rong Wu ◽  
Eun Kyeung Song ◽  
Debra K Moser ◽  
Terry A Lennie
Keyword(s):  
Heart Failure ◽  
African American ◽  
African Americans ◽  
Cardiac Event ◽  
Event Free Survival ◽  
Free Survival ◽  
Dietary Antioxidant ◽  
Patients With Heart Failure ◽  
Antioxidant Intake ◽  
Carotene Beta

Background: Heart failure is a chronic, burdensome condition with higher re-hospitalization rates in African Americans than Whites. Higher dietary antioxidant intake is associated with lower oxidative stress and improved endothelial function. Lower dietary antioxidant intake in African Americans may play a role in the re-hospitalization disparity between African American and White patients with heart failure. Objective: The objective of this study was to examine the associations among race, dietary antioxidant intake, and cardiac event-free survival in patients with heart failure. Methods: In a secondary analysis of 247 patients with heart failure who completed a four-day food diary, intake of alpha-carotene, beta-carotene, beta-cryptoxanthin, lutein, zeaxanthin, lycopene, vitamins C and E, zinc, and selenium were assessed. Antioxidant deficiency was defined as intake below the estimated average requirement for antioxidants with an established estimated average requirement, or lower than the sample median for antioxidants without an established estimated average requirement. Patients were followed for a median of one year to determine time to first cardiac event (hospitalization or death). Survival analysis was used for data analysis. Results: African American patients had more dietary antioxidant deficiencies and a shorter cardiac event-free survival compared with Whites ( p = .007 and p = .028, respectively). In Cox regression, race and antioxidant deficiency were associated with cardiac event-free survival before and after adjusting for covariates. Conclusion: African Americans with heart failure had more dietary antioxidant deficiencies and shorter cardiac event-free survival than Whites. This suggests that encouraging African American patients with heart failure to consume an antioxidant-rich diet may be beneficial in lengthening cardiac event-free survival.

Whole lung irradiation for completely responding pulmonary metastases in pediatric Ewing sarcoma

2020 ◽  
Vol 16 (15) ◽  
pp. 1043-1051
Author(s):  
Hagar Elghazawy ◽  
Azza Nasr ◽  
Iman Zaky ◽  
Manal Zamzam ◽  
Ahmed Elgammal ◽  
...  
Keyword(s):  
Pulmonary Metastases ◽  
Pediatric Population ◽  
Event Free Survival ◽  
Relapse Free Survival ◽  
Free Survival ◽  
Real Value ◽  
Lung Irradiation ◽  
Whole Lung Irradiation ◽  
The Impact

Aim: Scarce data assessing the real value of whole lung irradiation (WLI) in Ewing’s sarcoma (ES) with lung-only metastasis, with published conflicting results. We studied the impact of WLI in a homogenous pediatric population. Materials & methods: Retrospective study evaluating the survival outcomes of WLI in these patients. Results: Out of 163 metastatic ES; 41 patients were eligible for WLI. 30 patients (73.1%) received WLI (+ve) while 11 patients (26.8%) did not receive WLI (-ve). Five-year event-free survival was statistically significant in WLI (+ve). Five-year pulmonary relapse-free survival showed trend for improvement with WLI (+ve), while 5-year overall survival was not statistically significant between the two arms. Conclusion: WLI added significantly to the long term clinical outcome of metastatic ES patients, with no irreversible toxicity.

Dipyridamole technetium 99m sestamibi myocardial tomography as an independent predictor of cardiac event-free survival after acute ischemic events

1994 ◽  
Vol 1 (1) ◽  
pp. 72-82 ◽  
Author(s):  
D. Douglas Miller ◽  
Henry G. Stratmann ◽  
Leslee Shaw ◽  
Beaver R. Tamesis ◽  
Mark D. Wittry ◽  
...  
Keyword(s):  
Cardiac Event ◽  
Independent Predictor ◽  
Technetium 99M Sestamibi ◽  
Event Free Survival ◽  
Free Survival ◽  
Technetium 99M ◽  
Ischemic Events

scholarly journals Tortoise and hare win for SCD

Blood ◽  
2007 ◽  
Vol 110 (7) ◽  
pp. 2223-2224
Author(s):  
John F. Tisdale
Keyword(s):  
Stem Cell ◽  
Conditioning Regimen ◽  
Standard Of Care ◽  
Long Term Results ◽  
Cell Disease ◽  
Event Free Survival ◽  
Free Survival ◽  
Matched Donor ◽  
Over Time

Bernaudin and colleagues report, in this issue of Blood, the long-term results of the largest study of related myeloablative stem-cell transplantation for sickle cell disease (SCD). Their results show that slow, steady improvements over time, along with the addition of rabbit anti–thymocyte globulin (ATG) to the conditioning regimen, combine to produce an event-free survival (EFS) of 95.3%. They argue that for children with a suitable sibling-matched donor, myeloablative transplantation should be considered the standard of care in those at high risk for stroke.

Sign in / Sign up

Export Citation Format

Share Document