Abstract P58: Anxiety Burden from Cardioverter Defibrillators

Author(s):  
Gina Magyar-Russell ◽  
Gordon Tomaselli

This ongoing study identifies the prevalence of specific anxiety disorders and the clinical and self-reported functional effects of these disorders in a large sample of Implantable Cardioverter Defibrillator (ICD) recipients. To date, 143 recipients of ICDs were evaluated using the Structured Clinical Interview for DSM-IV-TR Axis I Disorders (SCID) to establish past and current anxiety disorder diagnoses. These data represent the largest sample of ICD recipients assessed using a structured clinical interview, the gold standard in psychiatric assessment. Self-report questionnaires were also administered to assess anxiety, depression, device-related appraisals, and functional impairment in work, social, and family life. Participants were 73% White, 80% male, 70% married and 27% currently working with a mean age of 64 (±11.5) years. Seventy shocked and 73 non-shocked ICD recipients were interviewed. History of an anxiety disorder was common. The greatest lifetime prevalence rates were for anxiety disorder due to general medical condition (GMC; 30%) and panic disorder (30%). The most common current anxiety disorders were anxiety disorder due to GMC (24%), generalized anxiety disorder (18%) and panic disorder (14%). Shocked participants were more likely to receive lifetime diagnoses of anxiety disorder due to GMC ( t = −2.21, p<.05) and posttraumatic stress disorder ( t = −2.32, p<.05), as well as current diagnoses of panic disorder ( t = −2.23, p<.05) and anxiety due to GMC ( t = −2.42, p<.05). Shocked participants also reported greater worry related to thoughts of receiving a shock ( t = −4.17, p<.01) and were more likely to report disability and impairment in their work ( t = −3.02, p<.01), social ( t = −3.38, p<.001), and family life ( t = −2.72, p<.01) in comparison to their non-shocked counterparts. No significant differences were found in self-reported symptoms of anxiety or depression between shocked and non-shocked participants. Findings characterize the extent, nature, and impact of clinical levels of anxiety among ICD recipients, including differences among shocked versus non-shocked individuals. Clinical applications and the development of appropriately tailored interventions will be discussed.

CNS Spectrums ◽  
2015 ◽  
Vol 21 (1) ◽  
pp. 70-75 ◽  
Author(s):  
Camilla Gesi ◽  
Marianna Abelli ◽  
Alessandra Cardini ◽  
Lisa Lari ◽  
Luca Di Paolo ◽  
...  

Objective/IntroductionHigh levels of comorbidity between separation anxiety disorder (SEPAD) and panic disorder (PD) have been found in clinical settings. In addition, there is some evidence for a relationship involving bipolar disorder (BD) and combined PD and SEPAD. We aim to investigate the prevalence and correlates of SEPAD among patients with PD and whether the presence of SEPAD is associated with frank diagnoses of mood disorders or with mood spectrum symptoms.MethodsAdult outpatients (235) with PD were assessed by the Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I), the Panic Disorder Severity Scale (PDSS), the Structured Clinical Interview for Separation Anxiety Symptoms (SCI-SAS), and the Mood Spectrum Self-Report Instrument (MOODS-SR, lifetime version).ResultsOf ther 235 subjects, 125 (53.2%) were categorized as having SEPAD and 110 (46.8%) as not. Groups did not differ regarding onset of PD, lifetime prevalence of obsessive compulsive disorder (OCD), social phobia, simple phobia, BD I and II, or major depressive disorder (MDD). SEPAD subjects were more likely to be female and younger; they showed higher rates of childhood SEPAD, higher PDSS scores, and higher MOODS-SR total and manic component scores than subjects without SEPAD.DiscussionSEPAD is highly prevalent among PD subjects. Patients with both PD and SEPAD show higher lifetime mood spectrum symptoms than patients with PD alone. Specifically, SEPAD is correlated with the manic/hypomanic spectrum component.ConclusionOur data confirm the high prevalence of SEPAD in clinical settings. Moreover, our findings corroborate a relationship between mood disorders and SEPAD, highlighting a relationship between lifetime mood spectrum symptoms and SEPAD.


Author(s):  
Gina Magyar-Russell ◽  
Christopher H Morrell ◽  
Gordon F Tomaselli

Trait anxiety is a dispositional factor that predisposes individuals to respond to perceived threats with more frequent and intense elevations in emotional states associated with arousal of the autonomic nervous system, which is thought to lead to the development of anxiety disorders. Trait anxiety has demonstrated promise in the empirical literature as a potential predictor of long term outcomes in ICD recipients. The present study adds novel information to this body of literature by studying the relation of trait anxiety to clinical diagnoses of anxiety disorders based on the Structured Clinical Interview for DSM-IV-TR Axis I Disorders (SCID). Two hundred and seven recipients of ICDs within the past five years were evaluated using the SCID to establish past and current anxiety disorder diagnoses. Self-report questionnaires were administered to assess device-related appraisals and functional impairment. Participants were 70% (n=144/207) male, 63% (n=130/207) married and 29% currently working (60/207) with a mean age of 63.0 (±12.3) years. Ninety-seven (47%) shocked and 110 (53%) non-shocked ICD recipients were interviewed. ICD recipients high in trait anxiety (n = 59/207, 29%) had significantly higher rates of current episodes of obsessive compulsive disorder (χ 2 = 9.05; p<.01), and anxiety disorder due to a general medical condition (GMC; χ 2 = 6.38; p<.05) during the first five years post ICD implant in comparison to those low in trait anxiety (n=147/207, 71%). Additionally, ICD recipients high in trait anxiety had significantly higher rates of a history of episodes of anxiety disorder due to GMC (χ 2 = 9.05; p<.001). ICD recipients high in trait anxiety (n = 59, 29%) reported greater device-related distress ( t = 5.65;p<.001), greater body image concerns ( t =2.39;p<.01), and greater fear of shock ( t = -3.98;p<.001), as well as fewer positive perceptions of their ICD ( t = 2.39; p<.05). Moreover, ICD recipients high in trait anxiety reported greater functional limitations ( t = 5.69; p<.001), and greater perceptions of disability in work, social, and family life ( t = -4.09; p<.001). Women (n=63/207; 30%) reported greater mean levels of trait anxiety ( t = -2.10; p<.05) and fear of shock ( t = -2.41; p<.05) in comparison to men. Individuals who met criteria for current panic disorder ( t = 2.86; p<.01), agoraphobia ( t = 4.78; p<.001), social phobia ( t = 3.04; p<.05), posttraumatic stress disorder ( t = 3.82; p<.01), and anxiety due to GMC ( t = 3.94; p<.001) were significantly younger than those without these diagnoses. The results from the current study suggest that assessment of trait anxiety may help clinicians identify individuals at risk for poor adjustment following ICD placement, even before implantation. Early identification of risk for maladjustment via pre-implant predictors might allow ICD recipients to enjoy the full benefits associated with these devices - longer and better quality of life.


2007 ◽  
Vol 41 (10) ◽  
pp. 836-842 ◽  
Author(s):  
Jane Phillips ◽  
Louise Sharpe ◽  
Stephen Matthey

Objective: Depression and anxiety are known to be common among women presenting to residential mother–infant programmes for unsettled infant behaviour but most studies have used self-report measures of psychological symptomatology rather than diagnostic interviews to determine psychiatric diagnoses. The aim of the present study was to determine rates of depressive and anxiety disorders and rates of comorbidity among clients of the Karitane residential mother–infant programme for unsettled infant behaviour. Method: One hundred and sixty women with infants aged 2 weeks–12 months completed the Edinburgh Postnatal Depression Scale and were interviewed for current and lifetime history of depressive and anxiety disorders using the Structured Clinical Interview for DSM-IV diagnosis (Research version). Results: A total of 25.1% of the sample met criteria for a current diagnosis of major depression, 31.7% had met criteria for major depression since the start of the pregnancy, and 30.5% of clients met criteria for a current anxiety disorder. Of note were the 21.6% who met criteria for generalized anxiety disorder or anxiety disorder not otherwise specified (worry confined to the topics of the baby or being a mother). High levels of comorbidity were confirmed in the finding that 60.8% of those with an anxiety disorder had experienced major or minor depression since the start of their pregnancy and 46.3% of those who had experienced depression since the start of their pregnancy also met criteria for a current anxiety disorder. Conclusions: There are high levels of psychiatric morbidity among clients attending residential mother–infant units for unsettled infant behaviour, highlighting the importance of providing multifaceted interventions in order to address both infant and maternal psychological issues.


Author(s):  
Ambreen Ghori ◽  
Aarti Gupta

This chapter reviews topics on anxiety disorders including panic disorder, specific phobia, social anxiety disorder, obsessive-compulsive disorder, posttraumatic stress disorder, acute stress disorder, generalized anxiety disorder, anxiety disorder due to a general medical condition, Substance/medication-induced anxiety disorder and body dysmorphic disorder


2011 ◽  
Vol 198 (3) ◽  
pp. 206-212 ◽  
Author(s):  
Julie Karsten ◽  
Catharina A. Hartman ◽  
Johannes H. Smit ◽  
Frans G. Zitman ◽  
Aartjan T. F. Beekman ◽  
...  

BackgroundPast episodes of depressive or anxiety disorders and subthreshold symptoms have both been reported to predict the occurrence of depressive or anxiety disorders. It is unclear to what extent the two factors interact or predict these disorders independently.AimsTo examine the extent to which history, subthreshold symptoms and their combination predict the occurrence of depressive (major depressive disorder, dysthymia) or anxiety disorders (social phobia, panic disorder, agoraphobia, generalised anxiety disorder) over a 2-year period.MethodThis was a prospective cohort study with 1167 participants: the Netherlands Study of Depression and Anxiety. Anxiety and depressive disorders were determined with the Composite International Diagnostic Interview, subthreshold symptoms were determined with the Inventory of Depressive Symptomatology–Self Report and the Beck Anxiety Inventory.ResultsOccurrence of depressive disorder was best predicted by a combination of a history of depression and subthreshold symptoms, followed by either one alone. Occurrence of anxiety disorder was best predicted by both a combination of a history of anxiety disorder and subthreshold symptoms and a combination of a history of depression and subthreshold symptoms, followed by any subthreshold symptoms or a history of any disorder alone.ConclusionsA history and subthreshold symptoms independently predicted the subsequent occurrence of depressive or anxiety disorder. Together these two characteristics provide reasonable discriminative value. Whereas anxiety predicted the occurrence of an anxiety disorder only, depression predicted the occurrence of both depressive and anxiety disorders.


CNS Spectrums ◽  
2006 ◽  
Vol 11 (S1) ◽  
pp. 2-4
Author(s):  
Iwona Chelminski

There is considerable symptom overlap and high levels of comorbidity between anxiety disorders and depression. The recognition of this comorbidity has both academic interest and clinical significance. Epidemiological studies have demonstrated that depressed individuals with a history of anxiety disorders are at increased risk for hospitalization, suicide attempt, and greater impairment from the depression. These individuals also tend to have a more chronic course of depression, as observed in psychiatric patients, primary care patients, and epidemiological samples. Van Valkenberg and colleagues reported that depressed patients with anxiety had poorer outcome and greater psychosocial impairment than those without an anxiety disorder. In the National Institute of Mental Health Collaborative Depression Study, the presence of panic attacks predicted a lower rate of recovery during the first 2 years of the follow-up interval. Similarly, Grunhaus found poorer outcome in depressed patients with comorbid panic disorder than in depressed patients without panic. In an 8-month follow-up study, depressed primary care patients with a history of generalized anxiety disorder (GAD) or panic disorder were less likely to have recovered from their depressive episode.Gaynes and colleagues prospectively followed primary care patients with major depressive disorder (MDD) every 3 months for 1 year after their initial diagnostic evaluation. At baseline, half of the original 85 patients had a coexisting anxiety disorder, the most frequent being social phobia (n=38). Twelve months after intake, 68 of the patients were available for the final interview. Those with a comorbid anxiety disorder were significantly more likely to still be in an episode of depression (82% vs 57%; risk ratio=1.44; 95% CI 1.02-2.04), and they experienced more disability days during the course of the 12 months than the depressed patients without an anxiety disorder (67.1 days vs 27.5 days).


Author(s):  
Daniel McFarland ◽  
Jimmie C. Holland

This chapter deals with anxiety in cancer patients as it presents in distress, adjustment disorders, and formal anxiety disorders. The implementation of distress screening is now used to capture patients who are at risk of a range of psychological complications that are addressed in this book. “Distress” covers the range of responses from the “normal” distress of fear, worry, and anxiety to formal defined psychiatric disorders. Adjustment disorders are the mildest level of psychiatric disorder occurring in relation to the stressor of a diagnosis with cancer or its treatment. Formal anxiety disorders typically antedate the cancer diagnosis and have clear symptom clusters defined by formal criteria. These include generalized anxiety disorder, panic disorder, phobias (e.g., needle, claustrophobia) and anxiety disorder due to another medical condition. These disorders require careful medical and psychiatric workup to identify potential etiologic stressors, agents, or responsible medical conditions.


2005 ◽  
Vol 27 (2) ◽  
pp. 97-100 ◽  
Author(s):  
Luciano Rassier Isolan ◽  
Cristian Patrick Zeni ◽  
Kelin Mezzomo ◽  
Carolina Blaya ◽  
Leticia Kipper ◽  
...  

PURPOSE: To evaluate the presence of behavioral inhibition and anxiety disorders during childhood in Brazilian adult patients with panic disorder and social anxiety disorder compared to a control group. METHODS: Fifty patients with panic disorder, 50 patients with social anxiety disorder, and 50 control subjects were included in the study. To assess the history of childhood anxiety, the Schedule for Affective Disorders and Schizophrenia for School Age Children, Epidemiologic Version (K-SADS-E), and the Diagnostic Interview for Children and Adolescents-Parent Version (DICA-P) were used. The presence of behavioral inhibition in childhood was assessed by the self-reported scale of Behavioral Inhibition Retrospective Version (RSRI-30). RESULTS: Patients showed significantly higher prevalence of anxiety disorders and behavioral inhibition in childhood compared to the control group. Patients with social anxiety disorder also showed significantly higher rates of avoidance disorder (46% vs. 18%, p = 0.005), social anxiety disorder (60% vs. 26%, p = 0.001), presence of at least one anxiety disorder (82% vs. 56%, p = 0.009) and global behavioral inhibition (2.89 ± 0.61 vs. 2.46 ± 0.61, p < 0.05) and school/social behavioral inhibition (3.56 ± 0.91 vs. 2.67 ± 0.82, p < 0.05) in childhood compared to patients with panic disorder. CONCLUSION: Our data are in accordance to the literature and corroborates the theory of an anxiety diathesis, suggesting that a history of anxiety disorders in childhood is associated with an anxiety disorder diagnosis, mainly social anxiety disorder, in adulthood.


2000 ◽  
Vol 16 (1) ◽  
pp. 53-58 ◽  
Author(s):  
Hans Ottosson ◽  
Martin Grann ◽  
Gunnar Kullgren

Summary: Short-term stability or test-retest reliability of self-reported personality traits is likely to be biased if the respondent is affected by a depressive or anxiety state. However, in some studies, DSM-oriented self-reported instruments have proved to be reasonably stable in the short term, regardless of co-occurring depressive or anxiety disorders. In the present study, we examined the short-term test-retest reliability of a new self-report questionnaire for personality disorder diagnosis (DIP-Q) on a clinical sample of 30 individuals, having either a depressive, an anxiety, or no axis-I disorder. Test-retest scorings from subjects with depressive disorders were mostly unstable, with a significant change in fulfilled criteria between entry and retest for three out of ten personality disorders: borderline, avoidant and obsessive-compulsive personality disorder. Scorings from subjects with anxiety disorders were unstable only for cluster C and dependent personality disorder items. In the absence of co-morbid depressive or anxiety disorders, mean dimensional scores of DIP-Q showed no significant differences between entry and retest. Overall, the effect from state on trait scorings was moderate, and it is concluded that test-retest reliability for DIP-Q is acceptable.


2018 ◽  
Author(s):  
Jon E Grant

Anxiety disorders are the most common psychiatric disorders among adults in the United States. Although anxiety disorders generally result in significant psychosocial impairment, most adults do not seek treatment until many years after the onset of the anxiety disorder. The treatment literature for anxiety disorder has grown tremendously since the 1980s, and both psychotherapy and medications may prove beneficial for people with anxiety disorders. This review presents a general overview of the anxiety disorders. This review contains 7 tables, and 33 references. Key words: agoraphobia, anxiety disorder, generalized anxiety disorder, panic disorder, separation anxiety disorder, social anxiety disorder, specific phobia, treatment of anxiety


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