Abstract 259: C-reactive Protein Ultrasensitive (hscrp) In Resistant Hypertensive Patients (rhtn) With Left Ventricular Hypertrophy (lvh)

Hypertension ◽  
2014 ◽  
Vol 64 (suppl_1) ◽  
Author(s):  
Nelson Dinamarco ◽  
Marileide Dinamarco ◽  
Heitor Moreno
Keyword(s):  
Left Ventricular Hypertrophy ◽  
Ventricular Hypertrophy ◽  
Inflammatory Marker ◽  
Strong Predictor ◽  
Vascular Diseases ◽  
Normal Subjects ◽  
Left Ventricular ◽  
Equal Distribution ◽  
Hypertensive Patients ◽  
Increased Risk

Introduction: Left ventricular hypertrophy (LVH) is an important cardiocerebrovascular risk factor and due to this fact, when present , in hypertensive patients should plan a more elaborate therapeutic treatment. The hsCRP is systemic inflammatory marker associated with increased risk of myocardial infarction and vascular diseases. Objective: Identify hsCRP as a strong biomarker with correlation with LVH in resistant hypertensive patients (RHTN). Methodology: A total of 180 patients: 60 RHTN and 60 RHTN with LVH with echocardiographic diagnosis (LVH-RHTN), compared to 60 normal subjects (control), with equal distribution of gender and age. The hs-CPR was measured using nephelometry method. Results: In LVH-RHTN hsCRP was 3.96 ± 1.11 mg/L and was significantly higher when compared with RHTN, which was 2.20 ± 0.53 mg/L, and with hsCRP 0.56 ± 0.23 in CON (p <0.001). There is a strong correlation between elevated hsCRP and LVH in patients with resistant hypertension, as shown by the Pearson coefficient (r = 0.74). Conclusion: hsCRP can be considered a strong predictor biomarker in presence of LVH in RHTN.

scholarly journals Evaluation of left ventricular hypertrophy in hypertensive patients with echocardiographic myocardial videodensitometry normalized by displacement

2010 ◽  
Vol 10 (4) ◽  
pp. 292-296 ◽  
Author(s):  
Xiao-Zhi Zheng ◽  
Lian-Fang Du ◽  
Hui-Ping Wang
Keyword(s):  
Left Ventricular Hypertrophy ◽  
Ventricular Hypertrophy ◽  
Accurate Determination ◽  
Normal Subjects ◽  
Posterior Wall ◽  
Left Ventricular ◽  
Hypertensive Patients ◽  
Tissue Tracking ◽  
Cardiovascular Morbidity And Mortality

Left ventricular hypertrophy (LVH) is an important predictor of cardiovascular morbidity and mortality. To investigate the feasibility of the myocardial grayscale intensity (GI) normalized by displacement (d) to discriminate between healthy and hypertrophic myocardium in hypertensive patients, sixty hypertensive patients and sixty age and sex-matched healthy volunteers were involved in this study. The peak d and the maximal GI [GI(max)] and minimal GI [GI(min)] for the middle interventricular septal (IVS) and the middle posterior wall (PW) at the level of papillary muscle were obtained from the standard parasternal long axis views using tissue tracking (TT) and videodensitometric analysis, respectively. The GI and the cyclic variation of GI (CVGI) normalized by d were calculated. The results showed that the d both for IVS and PW the amplitude of CVGI for IVS in hypertensive patients with LVH were smaller than the ones without LVH and the normal subjects. But, the CVGI/d both for IVS and PW in hypertensive patients with LVH were all greater than the ones without LVH and the normal subjects. Moreover, the parameter, CVGI/d correlated positively with left ventricular mass index (LVMI). So, the method employed in this study, videodensitometric analysis in combination with TT allow objective and accurate determination of LVH and CVGI/d is a sensitive indicator for hypertensive patients with LVH.

EVALUATION OF LEFT VENTRICULAR MASS IN THE PREHYPERTENSIVES BY ELECTROCARDIOGRAPHY AND ECHOCARDIOGRAPHY

2011 ◽  
pp. 119-125
Author(s):  
Thi Thuy Hang Nguyen
Keyword(s):  
Left Ventricular Hypertrophy ◽  
Left Ventricular Mass ◽  
Ventricular Hypertrophy ◽  
Structural Changes ◽  
Left Ventricular ◽  
Control Group ◽  
Concentric Left Ventricular Hypertrophy ◽  
Increased Risk ◽  
Lv Mass ◽  
Left Ventricular Morphology

Objective: Prehypertensive individuals are at increased risk for developing hypertension and their complication. Many studies show that 2/3 prehypertensive individuals develop hypertension after 4 years. ECG and echocardiography are the routine tests used to assess LV mass. The objective of the research to determine the percentage of change in left ventricular morphology in the ECG, echocardiography, which explore the characteristics of left ventricular structural changes by echocardiography in pre-hypertensive subjects. Materials and method: We studied a total of 50 prehypertensive, 30 males (60%) and 20 females (40%), mean age 48.20±8.47years. 50 normotensive volunteers as control participants. These subjects were examined for ECG and echocardiography. Results: In prehypertensive group, with 18% of left ventricular hypertrophy on electrocardiogram, 12% of left ventricular hypertrophy on echocardiography; in the control group, we did not find any subjects with left ventricular hypertrophy. In the group with left ventricular hypertrophy, mostly eccentric left ventricular hypertrophy (83.33%), concentric left ventricular hypertrophy is 16.67%. Restructuring of left ventricular concentric for 15.9% of subjects without left ventricular hypertrophy on echocardiography. Conclusion: There have been changed in left ventricular morphology even in prehypertensive

Common Carotid Artery Stiffness and Patterns of Left Ventricular Hypertrophy in Hypertensive Patients

Hypertension ◽  
1995 ◽  
Vol 25 (4) ◽  
pp. 651-659 ◽  
Author(s):  
Pierre Boutouyrie ◽  
Stéphane Laurent ◽  
Xavier Girerd ◽  
Athanase Benetos ◽  
Patrick Lacolley ◽  
...  
Keyword(s):  
Carotid Artery ◽  
Left Ventricular Hypertrophy ◽  
Common Carotid Artery ◽  
Ventricular Hypertrophy ◽  
Left Ventricular ◽  
Hypertensive Patients ◽  
Artery Stiffness

Cornell voltage left ventricular hypertrophy predicts all-cause mortality better than Sokolow-Lyon voltage in patients with and without diabetes – data from 183,749 primary care ECGs

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
S Haxha ◽  
U Pedersen-Bjergaard ◽  
J.B Nielsen ◽  
J Pallisgaard ◽  
R.B Devereux ◽  
...  
Keyword(s):  
Primary Care ◽  
Left Ventricular Hypertrophy ◽  
Predictive Value ◽  
Ventricular Hypertrophy ◽  
Strong Predictor ◽  
Multivariable Analysis ◽  
Left Ventricular ◽  
Type I ◽  
All Cause Mortality ◽  
Cornell Voltage

Abstract Background Cornell voltage criteria (CL) and Sokolow-Lyon criteria (SL) for electrocardiographic left ventricular hypertrophy (ECG-LVH) are well known predictors of cardiovascular outcome. However, their predictive value may differ according to patient type and remains to be further tested in diabetic mellitus (DM) patients. Purpose The present study aims to determine the prevalence of each ECG-LVH criteria and their respective predictive value in DM patients. Method A retrospective cohort study of individuals age &gt;40 years with digital ECGs from primary care were collected during 2001 to 2011. Data on medication, comorbidity, and outcomes were collected from Danish nationwide registries. DM was defined if individuals were prescribed oral antidiabetics or insulin, if they were diagnosed with DM type I or II, or had a HbA1c&gt;48 mmol/l. Cox multivariable analysis was used for estimating hazard ratio (HR) and 95% confidence intervals (95% CI) for all-cause mortality during follow-up of up to 17 years. Results Included were 183,749 individuals with a digital ECG collected in primary care. A total of 13,003 (7.1%) individuals had DM, they were older (65.8 vs. 61.3 years), had more myocardial infarction (16.1% vs. 5.2%), stroke (14.4% vs. 6.2%), hypertension (35.1% vs. 13.2%), CL LVH (8.0% vs. 5.6%) and more were males (53.3% vs. 45.3%) compared to the non-DM individuals (all p&lt;0.001). CL identified a larger percentage of LVH in DM compared to non-DM individuals (8.0% vs. 5.6%, p&lt;0.001), whereas SL identified similar percentage LVH in DM and non-DM individuals (8.5% vs. 8.1%, p=0.068). In multivariable adjusted analysis CL LVH remained strongly associated with all-cause mortality [HR 1.45 (95% CI: 1.42–1.48)] compared to SL LVH which found only a modest association [HR 1.06 (95% CI: 1.03–1.10)] (Figure 1). Of note, the association of CL LVH and all-cause mortality was even stronger than DM per se. There was no interaction with DM and either ECG LVH criteria (p&gt;0.45). Conclusion Cornell Voltage Left Ventricular Hypertrophy is a strong predictor of mortality in patients with and without diabetes and an independent risk factor compared to hypertension and diabetes. The predictive value was substantially stronger than Sokolow-Lyon Voltage criteria for hypertrophy. Figure 1. LVH and all-cause mortality Funding Acknowledgement Type of funding source: None

scholarly journals Prevalence and associated factors of electrocardiographic left ventricular hypertrophy in a rural community, central Thailand

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Patipan Viwatrangkul ◽  
Sakda Lawanwisut ◽  
Pondfah Leekhaphan ◽  
Tatchamon Prasart-intara ◽  
Pathomphon Phiensuparp ◽  
...  
Keyword(s):  
Left Ventricular Hypertrophy ◽  
Rural Community ◽  
Associated Factors ◽  
Ventricular Hypertrophy ◽  
Strong Predictor ◽  
Hypertensive Crisis ◽  
Cross Sectional Study ◽  
Left Ventricular ◽  
Cross Sectional ◽  
Cardiac Condition

AbstractLeft ventricular hypertrophy (LVH) is considered a cardiac condition with life-threatening complications. Detected LVH is a strong predictor of cardiovascular diseases and death. This condition is normally diagnosed at offices. We aimed to determine the prevalence and associated factors of electrocardiographic-LVH (ECG-LVH) among adults in a Thai rural community. A cross-sectional study was conducted in Na-Yao rural community of Thailand in 2020. A total of 638 individuals aged ≥ 20 years were interviewed using standardized structured questionnaires related to demographic information, risk behaviors, comorbidities and anthropometric measurements. LVH was determined by Sokolov-Lyon and Cornell criteria based on the collected electrocardiograms. The prevalence of ECG-LVH among adults was 6.6%. The factors independently associated with ECG-LVH were being male (AORs 2.04, 95% CI 1.05–3.98), history of diabetes mellitus (AORs 1.01, 95% CI 1.01–1.02), and hypertensive crisis ≥ 180/110 mmHg (AORs 7.24, 95% CI 1.31–39.92). However, resting heart rate was negatively associated with ECG-LVH (p < 0.05). Our data emphasized that LVH was one of the significant health problems among adults in a rural community. This condition could lead to severe complications. Thus, effective detection and public health interventions should be provided at the community level.

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