Abstract 120: A Multicenter Study of the Prevalence and Outcomes of Intracranial Large Artery Atherosclerosis among Stroke and TIA Patients in China

Stroke ◽  
2012 ◽  
Vol 43 (suppl_1) ◽  
Author(s):  
Yongjun Wang ◽  
Liping Liu ◽  
Yilong Wong ◽  
Yannie Soo ◽  
Yuehua Pu ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cerebral Ischemia ◽  
Multicenter Study ◽  
Recurrent Stroke ◽  
Intracranial Stenosis ◽  
Arterial Stenosis ◽  
Hospital Treatment ◽  
Large Artery ◽  
Acute Cerebral Ischemia ◽  
History Of

BACKGROUND The prevalence, characteristics and outcomes of stroke patients with intracranial large artery atherosclerosis have not been clearly established by large multicenter prospective study. METHODS In this prospective multicenter study, we evaluated 2864 consecutive patients (mean age, 62 years) who experienced an acute cerebral ischemia, including ischemic stroke or transient ischemic attack (TIA), within 7 days of symptom onset in 22 hospitals in China. All patients underwent magnetic resonance angiography (MRA), with measurement of diameter of the main intracranial arteries. Intracranial large artery atherosclerosis was defined as at least 50% diameter reduction on MRA. RESULTS The prevalence of intracranial stenosis was 46.6% (1,335 patients, including 261 patients with co-existing extracranial carotid stenosis). Patients with intracranial stenosis had more severe stroke at admission and stayed longer in hospitals than those without intracranial stenosis (median NIHSS 3 vs 5, ; median length of stay 14 vs 16 days respectively, both p<.0001). In hospital treatment included antithrombotics (96%), statins (76%), and antihypertensives (51%). After 12 months, recurrent stroke occurred in 3.34% of patients with no stenosis, 3.82% for 50-69% stenosis, 5.16% for 70-99% stenosis and 7.40% for 100% occlusion. Apart from the degree of arterial stenosis, age, family history of stroke, prior history of cerebral ischemia or heart disease and no prior use of antithrombotic drug were independent risk factors for recurrent stroke. The recurrent rate of each group of patients categorized by degree of stenosis and number of risk factor is shown in the Figure . The highest rate of recurrence was observed in patients with 100% occlusion with the presence of 3 additional risk factors. CONCLUSION Intracranial large artery stenosis is the commonest vascular lesion in patients with cerebrovascular disease in China. Recurrent stroke rates remains high in patients with severe stenosis and other risk factors despite prevalent use of medical treatment such as antiplatelet, antihypertensive and statin therapies.

scholarly journals Cerebral revascularization by EC-IC bypass in ischemic conditions of different etiologies

2020 ◽  
pp. 308-320
Author(s):  
Forhad H Chowdhury ◽  
Mohammod Raziul Haque ◽  
Jalaluddin Muhammad Rumi ◽  
Maliha Hakim ◽  
Sharif Uddin Khan ◽  
...  
Keyword(s):  
Cerebral Ischemia ◽  
Recurrent Stroke ◽  
Case Series ◽  
Positive Outcome ◽  
Arterial Stenosis ◽  
Cerebral Revascularization ◽  
Doppler Imaging ◽  
Vessel Occlusion ◽  
History Of

Background: Even after the failure of EC-IC bypass trial, EC- IC bypass can help many patients in preventing future stroke. Here we present a case series of patients with cerebral ischemia from different etiological modes who underwent EC-IC bypass with positive end results. Methods: Patients in these cases series with TIA/stroke/recurrent stroke were evaluated clinically for the history of TIA or recurrent/hemodynamic TIA (in rest or during work) or progressive hemiparesis/aphasia/visual disturbances or sudden hemiplegia/hemiparesis/aphasia with subsequent significant (days to a week) recovery. MRI of the brain was done in ischemic protocol in all cases. To see the arterial pathology dynamic CTA was also done in all cases except one case. DSA was done in 03 cases. When clinical features, cerebral ischemia on MRI and arterial stenosis/occlusion on angiogram were concordant with each other, only then cerebral revascularization was done. After bypass, all patients were followed up regularly. All recorded data were reviewed retrospectively. Results: Total no. of cases were 08. The most common presentation was hemiparesis. Etiologies were infective thrombosis of ICA, orbital cellulitis, thrombosed giant ICA aneurysm, single & multiple vessel occlusion and MCA stenosis. High flow EC-IC bypass was done in one case. STA- MCA bypass was done in rest of the cases. All patient were ambulant with static neuro-status without new stroke till last follow up. All bypasses were patent and functioning till last follow up (clinical, Doppler/Imaging). Conclusion: In carefully selected cases cerebral revascularization in ischemic conditions can result positive outcome.

scholarly journals Clinical features of recurrent stroke after intracerebral hemorrhage

2012 ◽  
Vol 4 (2) ◽  
pp. 10 ◽  
Author(s):  
Taizen Nakase ◽  
Shotaroh Yoshioka ◽  
Masahiro Sasaki ◽  
Akifumi Suzuki
Keyword(s):  
Risk Factors ◽  
Intracerebral Hemorrhage ◽  
Recurrent Stroke ◽  
Brain Infarction ◽  
Brain Magnetic Resonance Imaging ◽  
Stroke Recurrence ◽  
Amyloid Angiopathy ◽  
Large Artery ◽  
Small Artery Occlusion ◽  
History Of

There have been many reports about the prognosis and risk factors of stroke recurrence following brain infarction (BI). However, little is known about the stroke recurrence after primary intracerebral hemorrhage (PICH). Therefore, we explored the recurrent stroke patients after initial PICH retrospectively, to reveal the critical factors of stroke recurrence. Acute BI (n=4013) and acute PICH patients (n=1067) admitted to the hospital between April 2000 and March 2009 were consecutively screened. PICH patients with a history of ICH and BI patients with a history of ICH were then classified into the ICH-ICH group (n=64, age 70.8±9.5 years) and ICH-BI group (n=52, age 72.8±9.7years), respectively. ICH lesions were categorized into ganglionic and lober types according to the brain magnetic resonance imaging. Subtypes of BI were classified into cardioembolism, large-artery atherosclerosis, small-artery occlusion and others. There was no difference in incidence of risk factors between ICH-ICH and ICH-BI groups. Distribution of initial PICH lesions was significantly abun- dant in the lobar type in the ICH-ICH group (P&lt;0.01) and in ganglionic type in the ICH-BI group (P&lt;0.02). Age of onset was significantly older in recurrent lobar ICH compared with recurrent ganglionic ICH (P&lt;0.01: 73.6±10.0 and 59.1±9.0 years, respectively). In conclusion, ganglionic ICH patients may have a chance of recurrent stroke in both brain infarction and ganglionic ICH, suggesting the participation of atherosclerosis in intracranial arteries. Lobar ICH patients were older and prone to recurrent lobar ICH, suggesting the participation of cerebral amyloid angiopathy as a risk of stroke recurrence.

EXPRESS: Risk factors for delayed-onset dementia after stroke or transient ischemic attack - A 5-year longitudinal cohort study

2021 ◽  
pp. 174749302110265
Author(s):  
Moamina Ismail ◽  
Vincent CT Mok ◽  
Adrian Wong ◽  
Lisa Au ◽  
Brian Yiu ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cohort Study ◽  
Ischemic Stroke ◽  
Recurrent Stroke ◽  
Early Onset Dementia ◽  
Delayed Onset ◽  
Lower Baseline ◽  
History Of ◽  
Ischemic Attack ◽  
Moca Score

Background Stroke not only substantially increases the risk of incident dementia early after stroke, the risk remains elevated years after. Aim We aimed to determine the risk factors of dementia onset more than 3-6 months after stroke or transient ischemic attack (TIA). Methods This is a single center prospective cohort study. We recruited consecutive subjects with stroke/TIA without early-onset dementia. We conducted an annual neuropsychological assessment for 5 years. We investigated the association between baseline demographic, clinical, genetic (APOEε4 allele), and radiological factors, as well as incident recurrent stroke, with delayed-onset dementia using Cox proportional hazards models. Results 1,007 patients were recruited, of which 88 with early-onset dementia and 162 who lost to follow-ups were excluded. 49 (6.5%) out of 757 patients have incident delayed-onset dementia. The presence of ≥ 3 lacunes, history of ischemic heart disease (IHD), history of ischemic stroke and a lower baseline Hong Kong version of the Montreal Cognitive Assessment (MoCA) score, were significantly associated with delayed-onset dementia. APOEε4 allele, medial temporal lobe atrophy, and recurrent stroke were not predictive. Conclusion The presence of ≥ 3 lacunes, history of IHD, history of ischemic stroke and a lower baseline MoCA score, are associated with delayed-onset dementia after stroke/TIA.

Abstract TMP90: Frequency and Risk Factors for Early Neurological Deterioration Among Hyperacute Cerebral Ischemia Patients Treated With and Without Thrombolysis

Stroke ◽  
2020 ◽  
Vol 51 (Suppl_1) ◽  
Author(s):  
Christa D Brown ◽  
Gilda Avila-Rinek ◽  
Nerses Sanossian ◽  
Sidney Starkman ◽  
Scott Hamilton ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cerebral Ischemia ◽  
Fold Increase ◽  
Information Criteria ◽  
Neurological Deterioration ◽  
Stroke Severity ◽  
Acute Cerebral Ischemia ◽  
Early Neurological Deterioration ◽  
Prior Stroke ◽  
Iv Tpa

Background: Early neurological deterioration (END) is a feared complication of acute cerebral ischemia. However, estimates of END frequency vary widely, rates have not been systematically examined in hyperacute patients presenting within the first 2h of onset, nor separately in patients treated with and without thrombolysis, and risk factors for END have not been well delineated. Methods: We analyzed patients with a final diagnosis of acute cerebral ischemia in the NIH FAST-MAG Phase 3 multicenter clinical trial. END was defined as worsening post-admission by ≥ 4 NIHSS points up to Day 4. We separately analyzed patients who did and did not receive IV tPA. Results: Among 1245 acute cerebral ischemia patients transported by EMS to 55 stroke centers, time from last known well (LKW) to ED arrival was median 59 mins (IQR 80-46), and 36.1% received IV tPA. Overall, 211 (16.9%) experienced END by Day 4, with a greater proportion of END in tPA than non-tPA patients (21.2% vs 14.5%, p=0.003). In multivariate analysis, from 26 candidate variables, among tPA recipients, independent predictors of END were: age (OR 1.03/year, 95%CI 1.01-1.05), diastolic BP (OR 1.01/mm Hg, 95%CI 1.00-1.03), prior stroke (OR 1.65, 95%CI 0.98-2.77), glucose (OR 11.06/10 fold increase, 95%CI 1.90-64.44), and worse ASPECTS score (OR 0.85/point, 95%CI 0.78-0.92). Among non-tPA recipients, independent predictors of END were: more severe NIHSS (OR 1.08/point, 95%CI 1.05-1.11), glucose (OR 8.88/10 fold increase, 95%CI 1.83-43.12), and h/o hypertension (OR 2.62/mm Hg, 95%CI 1.25-5.48), with Akaike information criteria identifying SBP, shorter LKW-to-ED time, and absence of anticoagulant agents as additional contributors. C statistics for these models were 0.68 for tPA patients and 0.73 for non-tPA patients. Conclusions: Among hyperacute cerebral ischemia patients, END occurs in 1 in 5 who receive tPA, and 1 in 7 who do not receive tPA. Greater initial stroke severity (on neurologic exam or imaging), higher glucose, and hypertension increase risk of END for both lytic and non-lytic patients, with older age and prior stroke additionally increasing END risk with tPA. Models based on these risk factors show fair to good performance identifying patients who will experience END after hospital admission.

scholarly journals Intracranial Atherosclerosis in Stroke Patients, Which Risk Factors Are Important? A Study From Mixed Ethnic Population in Singapore.

2021 ◽  
Author(s):  
shrikant Pande ◽  
May Thiri Lwin ◽  
Aye Aye Khine ◽  
May Win Myat ◽  
Lorecar Lolong ◽  
...  
Keyword(s):  
Risk Factors ◽  
Multivariable Analysis ◽  
Large Artery ◽  
Intracranial Atherosclerosis ◽  
Stroke Patients ◽  
Term Survival ◽  
Significant Stenosis ◽  
Proactive Management ◽  
History Of

Abstract Intracranial atherosclerosis (ICAD) although more common in Asians, has not been studied from Singapore population. The aim of this study is to identify prevalence ICAD in stroke subjects, its association with comorbidities, stroke subtypes and long-term survival. We performed retrospective analysis of 681 stroke patients, 327(48%) had ICAD) with 232 (71%) having one or more intracranial artery with significant stenosis. ICAD was associated with older age, ischaemic strokes, total anterior circulation syndrome (TACS), large artery strokes (p<0.001), peripheral vascular disease (PVD, p=0.018), diabetes mellitus (DM), and with history of hyperlipidemia. In addition, higher serum potassium (p=0.046) and glucose (p<0.001), lower haemoglobin (p=0.040) and aortic valve sclerosis were significantly associated with ICAD (p<0.001). Multivariable analysis showed a significant independent association of ICAD with advancing age, history of hyperlipidemia and DM.In ischemic strokes (489), 311(64%) had ICAD of which 229(72%) had significant stenosis. Of the 192 hemorrhagic strokes, 16 (8%) had ICAD.Conclusion: The prevalence of ICAD, especially in ischemic strokes, from our study is high. As modifiable risk factors such as hyperlipidemia and DM appear to be associated with ICAD, then proactive management of these conditions may improve long term associated complications. Prospective studies may help to validate our findings.

scholarly journals Comparison of metabolic phenotypes and BMI as indicators of recurrent stroke in Chinese hospitalized stroke patients: a retrospective study

2021 ◽  
Author(s):  
Xiaolin Huang ◽  
Jiaojiao Zhou ◽  
Hong Zhang ◽  
Pei Gao ◽  
Long Wang ◽  
...  
Keyword(s):  
Risk Factors ◽  
Recurrent Stroke ◽  
Population Based ◽  
Metabolic Status ◽  
Stroke Patients ◽  
Population Based Study ◽  
Metabolic Phenotypes ◽  
History Of ◽  
Integrated Discrimination Improvement ◽  
Conventional Risk Factors

Abstract Background Metabolic status and body mass index (BMI) are known as apparent risk factors of recurrent stroke, but which one is more likely related to recurrent stroke remains uncertain. This study aimed to compare the metabolic phenotypes and BMI as indicators of recurrent stroke in Chinese hospitalized stroke patients. Methods In this retrospective population-based study, 856 hospitalized stroke patients from the Third Affiliated Hospital of Soochow University were enrolled. Recurrent stroke was defined as newly-onset stroke patients with a history of previous stroke. Metabolic phenotypes were based on Adult Treatment Panel III criteria. BMI ≥ 25kg/m2 was defined as obesity. Results Among the hospitalized stroke patients, the prevalence of recurrent stroke was 21.9%. Metabolic phenotypes rather than BMI were significantly associated with recurrent stroke. Compared with metabolically healthy patients, metabolically unhealthy ones had 72% (odds ratio [OR] = 1.72, 95% confidence interval [CI] 1.01–2.68) increased recurrent stroke, regardless of BMI and other confounding factors. Whereas, no statistical association between BMI and recurrent stroke were found. Metabolic status improved risk prediction of recurrent stroke when adding to conventional risk factors (net reclassification index 17.6%, P = 0.0047; integrated discrimination improvement 0.7%, P = 0.014), while BMI did not. Conclusions Recurrent stroke was likely associated with poor metabolic status rather than with BMI, suggesting that controlling metabolic abnormalities could be an important method for recurrent stroke prevention.

Abstract 107: Cardiovascular Risk Predictors Among Black and African American Women: A Preliminary Analysis of the P4 Study

2017 ◽  
Vol 10 (suppl_3) ◽  
Author(s):  
Obiora E Egbuche ◽  
Meldra Hall ◽  
Folake Ojutalayo ◽  
Ernest Alemah-Mensah ◽  
Brenda Lankford ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Disease ◽  
African American ◽  
African American Women ◽  
Personal History ◽  
Large Artery ◽  
American Women ◽  
Vascular Compliance ◽  
History Of ◽  
Survey Responses

Objective: To identify predictors that allow for early detection of cardiovascular disease in African American women Background: Cardiovascular (CV) mortality is high in African Americans in the United States. Cardiovascular disease (CVD) remains the leading cause of death in African American females. We hypothesize that certain cardiovascular risk factors are predictors of abnormal peripheral vascular compliance. We aim to identify determinants of abnormal vascular compliance by assessing the association between known CVD risk factors and the extent of vascular compliance Methods: This cross-sectional study utilized survey responses and results from a noninvasive screening tool. The study included only African American women. Traditional CV risk factors were independent variables (history of hypertension, high serum lipids, family or personal history of CVD). The instrument employed biomarkers that detect blood vessel elasticity. Outcome measures included small and large vessel compliance. Both survey responses and screening results were obtained from 70 consecutive participants. We conducted a univariate and bivariate descriptive analysis. A Chi-square or Fishers exact test was used to determine the significance as appropriate. We adjusted for potential confounders in our multivariable analysis. SAS 9.4 software was used for all the data analyses Results: Our study indicates that personal history of cardiovascular disease is strongly associated with abnormal small vessel compliance (Pvalue - 0.01). Family history of cardiovascular disease is strongly associated with abnormal large artery compliance (Pvalue - 0.02). History of cardiovascular disease in both parents is associated with abnormal large artery compliance (Pvalue - 0.04). Interestingly, Living Situation (Living alone) was associated with abnormal large artery compliance (Pvalue - 0.03) Conclusion: Family and personal history of CVD, and living alone have strong associations with abnormal vascular compliance. Cardiovascular mortality is high in Black and African American females. Identifying predictors of abnormal vascular compliance can allow for early disease detection and intervention.

Abstract 3094: Diffusion-Positive Cerebral Ischemia with Transient Symptoms - Is it Transient Ischemic Attack or Minor Ischemic Stroke? A Formal Analysis of Demographics, Risk Factors, and Prognosis

Stroke ◽  
2012 ◽  
Vol 43 (suppl_1) ◽  
Author(s):  
Yongseok Lee ◽  
David S Liebeskind ◽  
Latisha Ali ◽  
Sidney Starkman ◽  
Doojin Kim ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Cerebral Ischemia ◽  
Recurrent Stroke ◽  
Formal Analysis ◽  
Stroke Recurrence ◽  
Large Artery ◽  
Minor Ischemic Stroke ◽  
Artery Disease ◽  
Cerebral Ischemic ◽  
Definition Of

Background: The classification of patients with minor cerebral ischemic events is evolving. Under the classical time-based definition of TIA, cerebral infarcts with transient symptoms (CITS) were classified as TIA, while it is classified as minor ischemic stroke (MIS) under the modern tissue-based definition. However, arguments for this reclassification have been largely based on pathologic principles rather than formal analysis of whether CITS patients clinically more resemble DWI-negative TIA patients or MIS patients in demographics, clinical features, and prognosis. Methods: We analyzed consecutive patients recorded in a prospectively maintained database with symptoms of presumed focal ischemic origin either lasting less than 24 hours or with minor neurologic deficits (NIHSS≤5) lasting more than 24 hours. Patients had to present within 48 hours of symptom onset and have undergone acute DWI. Patients were excluded if ischemia occurred immediate after carotid endarterectomy or stenting. Clinical variables, ABCD 2 score, presence of DWI abnormality, relevant large artery disease (≥ 50% stenosis or occlusion of ipsilateral intracranial or extracranial vessels), and stroke recurrence within 90 days were recorded for analysis. Results: Among 416 patients meeting inclusion criteria (mean age 67 years, female 47.1%), 108 (26.0%) were CITS, 149 (35.8%) were DWI-negative TIA, and 159 (38.2%) were MIS. Compared with DWI-negative TIA patients, CITS patients were younger (65 vs. 70 years, p=0.017), had more coronary artery disease (25.9% vs. 14.1%, p=0.024) and relevant large artery disease (45.2% vs. 20.8%, p<0.001). In contrast, only diabetes differed between CITS and MIS patients (16.7% vs. 29.7%, p=0.027). The frequency of recurrent stroke was not different between MIS and CITS patients (16.0% vs. 12.3%, p>0.05), however, both were substantially higher than in DWI-negative TIA patients (2.5%). In multivariate logistic regression analysis performed across the entire cohort, the independent predictors of recurrent stroke were presence of DWI lesion (OR 4.95, 95% CI 1.11-22.09) and relevant large artery disease (OR 3.58, 95% CI 1.47-8.73). Conclusion: DWI-positive cerebral ischemia with transient symptoms more resembles MIS than DWI-negative TIA in risk factor profile and prognosis of patients. DWI abnormality and large artery disease, rather than clinical variables, are the predominant determinants of early stroke recurrence. These results emphasize the utility of urgent MR imaging in patients with minor cerebral ischemic episodes and support the rationale of tissue-based definition of TIA over time-based definition.

scholarly journals Risk Factors and Etiology of Young Ischemic Stroke Patients in Estonia

2017 ◽  
Vol 2017 ◽  
pp. 1-7 ◽  
Author(s):  
Siim Schneider ◽  
Alina Kornejeva ◽  
Riina Vibo ◽  
Janika Kõrv
Keyword(s):  
Risk Factors ◽  
Ischemic Stroke ◽  
Recurrent Stroke ◽  
Age Groups ◽  
Young Patients ◽  
Substantial Part ◽  
Large Artery ◽  
Stroke Patients ◽  
Young Stroke ◽  
First Time

Objectives. Reports on young patients with ischemic stroke from Eastern Europe have been scarce. This study aimed to assess risk factors and etiology of first-ever and recurrent stroke among young Estonian patients. Methods. We performed a retrospective study of consecutive ischemic stroke patients aged 18–54 years who were treated in our two hospitals from 2003 to 2012. Results. We identified 741 patients with first-ever stroke and 96 patients with recurrent stroke. Among first-time patients, men predominated in all age groups. The prevalence of well-documented risk factors in first-time stroke patients was 83% and in the recurrent group 91%. The most frequent risk factors were hypertension (53%), dyslipidemia (46%), and smoking (35%). Recurrent stroke patients had fewer less well-documented risk factors compared to first-time stroke patients (19.8 versus 30.0%, P=0.036). Atrial fibrillation was the most common cause of cardioembolic strokes (48%) and large-artery atherosclerosis (LAA) was the cause in 8% among those aged <35 years. Compared to first-time strokes, recurrent ones were more frequently caused by LAA (14.3 versus 24.0%, P=0.01) and less often by other definite etiology (8.5 versus 1.0%, P=0.01). Conclusions. The prevalence of vascular risk factors among Estonian young stroke patients is high. Premature atherosclerosis is a cause in a substantial part of very young stroke patients.

scholarly journals The prevalence of intracranial stenosis in patients at low and moderate risk of stroke

2019 ◽  
Vol 12 ◽  
pp. 175628641986953
Author(s):  
Hong-xiu Chen ◽  
Li-juan Wang ◽  
Yi Yang ◽  
Fei-xue Yue ◽  
Li-min Chen ◽  
...  
Keyword(s):  
Risk Factors ◽  
Stroke Risk ◽  
Transcranial Doppler Ultrasound ◽  
Personal History ◽  
Arterial Stenosis ◽  
Odds Ratios ◽  
Moderate Risk ◽  
Risk Patients ◽  
History Of ◽  
Different Levels

Background: Previous studies assessing the risk of stroke in the general population performed screening with Doppler ultrasonography only for high-risk patients and neglected low- and moderate-risk patients. The aims of this study were to explore the current prevalence of intracranial arterial stenosis (ICAS) and analyze its association with different levels of stroke risk and risk factors based on the risk assessment scale for stroke used in China. Methods: A total of 3654 participants who underwent transcranial Doppler ultrasound (TCD) were eligible for inclusion. Information regarding demographic characteristics and risk factors such as alcohol consumption and hypertension was collected through interviews and questionnaires and used to analyze the association of ICAS with different levels of stroke risk and risk factors. Results: The mean age of 501 subjects diagnosed with at least one ICAS was higher than that of participants without ICAS (57.13 ± 9.56 years and 55.52 ± 9.35 years, respectively). After adjusting for confounding factors, gender, education, residence, hypertension and personal history of stroke were associated with ICAS. The odds ratios for ICAS in patients with hypertension and a personal history of stroke were 1.655 [95% confidence interval (CI): 1.341–2.043] and 1.854 (95% CI: 1.371–2.508), respectively. In addition, participants in the low- and moderate-risk stroke groups accounted for an unexpectedly high proportion of individuals with ICAS (up to 38.3%). Results from multivariate analyses indicated that the adjusted odds ratios for ICAS in patients with moderate and high stroke risks versus those with a low stroke risk were 1.603 (95% CI: 1.171–2.195) and 1.612 (95% CI: 1.272–2.042), respectively. Conclusion: The prevalence of ICAS is high in northeast China and increases with the level of stroke risk. However, the proportion of patients with ICAS among those with low and moderate stroke risks should also be noted.

Sign in / Sign up

Export Citation Format

Share Document