Abstract WP518: Use of American Heart Association/American Stroke Association Secondary Stroke Prevention Recommendations in Hispanic/Latino Adults With Stroke/TIA: The Hispanic Community Health Study/Study of Latinos

Background:Chronic stress and/or lifetime traumatic stress can create a self-reinforcing cycle of unhealthy behaviors, such as overeating and sedentary behavior, that can lead to further increases in stress. This study examined the relationship between stress and sedentary behavior in a sample of Hispanic/Latino adults (N = 4244) from the Hispanic Community Health Study/Study of Latinos Sociocultural Ancillary Study.Methods:Stress was measured as the number of ongoing difficulties lasting 6 months or more and as lifetime exposure to traumatic events. Sedentary behavior was measured by self-report and with accelerometer. Multivariable regression models examined associations of stress measures with time spent in sedentary behaviors adjusting by potential confounders.Results:Those who reported more than one chronic stressor spent, on average, 8 to 10 additional minutes per day in objectively measured sedentary activities (P < .05), whereas those with more than one lifetime traumatic stressor spent (after we adjusted for confounders) 10 to 14 additional minutes in sedentary activities (P < .01) compared with those who did not report any stressors. Statistical interactions between the 2 stress measures and age or sex were not significant.Conclusion:Interventions aimed at reducing sedentary behaviors might consider incorporating stress reduction into their approaches.

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Smoking cessation among U.S. Hispanic/Latino adults: Findings from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL)

Preventive Medicine ◽

10.1016/j.ypmed.2015.10.006 ◽

2015 ◽

Vol 81 ◽

pp. 412-419 ◽

Cited By ~ 12

Author(s):

Cheryl R. Merzel ◽

Carmen R. Isasi ◽

Garrett Strizich ◽

Sheila F. Castañeda ◽

Marc Gellman ◽

...

Keyword(s):

Smoking Cessation ◽

Community Health ◽

Health Study ◽

Hispanic Community ◽

Latino Adults

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Abstract P071: Association of Baseline Depressive Symptoms With 6-Year Incidence of Diabetes in the Hispanic Community Health Study/Study of Latinos

Circulation ◽

10.1161/circ.137.suppl_1.p071 ◽

2018 ◽

Vol 137 (suppl_1) ◽

Author(s):

Matthew J O'Brien ◽

Mercedes R Carnethon ◽

Frank J Penedo ◽

Karen M Tabb ◽

Sylvia Wassertheil-Smoller ◽

...

Keyword(s):

Depressive Symptoms ◽

Community Health ◽

Self Report ◽

Incident Diabetes ◽

Health Study ◽

Incidence Density ◽

Diabetes Incidence ◽

Central Americans ◽

Hispanic Community ◽

Latino Adults

Background: Among Hispanics/Latinos, there is substantial heterogeneity in the prevalence of depressive symptoms and diabetes by background. This study aimed to examine the association between depressive symptoms and incident diabetes among Hispanic/Latino adults of diverse backgrounds. Methods: The Hispanic Community Health Study/Study of Latinos (HCHS/SOL) is a prospective, community-based study of 16,415 self-identified Hispanic/Latino adults aged 18-74 years at Visit 1 (2008-2011) and 10,914 who have also completed the Visit 2 examination by August 2017. This analysis includes 8,804 participants who were free from diabetes at baseline and attended both Visits. Baseline depressive symptoms were assessed using the CES-D 10-item depression scale and divided into quartiles. Incident diabetes was defined by fasting glucose ≥126mg/dL, 2-hour postload glucose 140-199mg/dL, HbA1c ≥6.5%, or self-report. Accounting for HCHS/SOL complex survey design, we used Poisson regression models to estimate diabetes incidence density ratios (Table). Results: Baseline BMI was associated with both depressive symptoms and incident diabetes. Overall, 876 participants developed diabetes. In analyses stratified by Hispanic/Latino background, the association between baseline depressive symptoms and incident diabetes was significant for South Americans, Central Americans, and Mexicans. No significant associations between depressive symptoms and diabetes were seen among Hispanics/Latinos of Dominican, Cuban, or Puerto Rican backgrounds. Conclusions: These findings suggest that the association between depressive symptoms and incident diabetes in Hispanics/Latinos may differ by their background, with South and Central Americans at the highest risk. This difference may be partly explained by variation in participants’ understanding of CES-D questions by Hispanic/Latino background. Future research is needed to understand these novel findings fully and explore their implications for practice and policy.

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Abstract 52: Plasma Metabolomic Signatures of the American Heart Association Diet Score: Findings From the Boston Puerto Rican Health Study

Circulation ◽

10.1161/circ.141.suppl_1.52 ◽

2020 ◽

Vol 141 (Suppl_1) ◽

Cited By ~ 1

Author(s):

Danielle E Haslam ◽

Jun Li ◽

Liming Liang ◽

Clary Clish ◽

Alice H Lichtenstein ◽

...

Keyword(s):

Risk Factors ◽

Puerto Rican ◽

American Heart Association ◽

Cardiometabolic Risk ◽

American Heart ◽

Metabolic Response ◽

Heart Association ◽

Dietary Guidelines ◽

Health Study ◽

Diet Score

Introduction: Puerto Rican adults living on the US mainland tend to have poor quality diets and adverse cardiometabolic risk. Plasma metabolomic signatures reflect dietary intakes and variability in metabolic response to diet. Hypothesis: A plasma metabolomic signature reflecting adherence to the American Heart Association (AHA) dietary guidelines will be associated with cardiometabolic risk. Methods: We used LC/MS to measure plasma metabolites (>700) among Boston Puerto Rican Health Study participants, aged 45-75 years, without (n=252) and with (n=254) type 2 diabetes (T2D). We calculated a modified version of a previously validated AHA diet score (AHA-DS), which included variety and amounts of fruits/vegetables, whole grains, fish, saturated fat, trans fat, sodium, and added sugars. We used elastic net regression to identify a metabolomic signature that associated with higher adherence to the AHA-DS among those without T2D (training set) and replicated the associations among those with T2D (testing set). A metabolomic score was calculated as the weighted sum of the diet associated metabolites. We used general linear models to determine the cross-sectional associations between the AHA-DS, metabolomic score, and cardiometabolic risk factors. Results: A diet-associated metabolomic signature with 58 metabolites, primarily lipids and amino acids, was identified. This metabolomic score correlated moderately with the AHA-DS among those with and without T2D (r=0.42-0.46, P <5.7x10 -12 ). In all participants (n=506), the metabolomic score, but not the AHA-DS, was significantly associated with higher HDL-C and LDL-C concentrations, and lower waist circumference ( P <0.004; Table 1). No associations were observed for triglyceride concentrations, glycemia measures, or blood pressure. Conclusions: In individuals of Puerto Rican descent, we identified a metabolomic signature that reflected adherence and metabolic response to the AHA dietary guidelines and that associated with cardiometabolic risk factors.

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Adherence to Pre-pregnancy DASH Dietary Pattern and Diet Recommendations from the American Heart Association and the Risk of Preeclampsia (OR35-06-19)

Current Developments in Nutrition ◽

10.1093/cdn/nzz048.or35-06-19 ◽

2019 ◽

Vol 3 (Supplement_1) ◽

Cited By ~ 1

Author(s):

Mariel Arvizu ◽

Jennifer Stuart ◽

Janet Rich-Edwards ◽

Audrey Gaskins ◽

Bernard Rosner ◽

...

Keyword(s):

Dietary Pattern ◽

American Heart Association ◽

American Heart ◽

Smoking Status ◽

Heart Association ◽

Dietary Guidelines ◽

Health Study ◽

Dash Score ◽

Food Groups ◽

Whole Grain

Abstract Objectives Because the relationship between diet and hypertensive disorders of pregnancy (HDPs), including preeclampsia, remains unclear we aim to evaluate the association between pre-pregnancy adherence to the American Heart Association (AHA) diet recommendations and the Dietary Approaches to Stop Hypertension (DASH) dietary pattern with risk of developing preeclampsia (PE). Methods Our prospective cohort study included 20,024 pregnancies from 13,645 women enrolled in the Nurses’ Health Study II (NHS2) (1991 to 2007). Pre-pregnancy diet was measured in 1991 by a semi-quantitative food frequency questionnaire and updated every four years. Pregnancy outcomes were self-reported every 2 years during follow-up. We derived the DASH scores based on the intake of 8 food groups (fruits and fruit juices, vegetables, whole-grain, red and processed meats, nuts and legumes, sugar sweetened beverages, and sodium). The AHA score was derived from 5 food groups (fruits and vegetables, whole grain, fish, SSBs and sodium) consistent with AHA dietary guidelines to reduce hypertension in the general population. We estimated the RR and 95% CIs of PE by log-Poisson regression employing generalized estimating equations and adjusting for total energy intake, age at pregnancy, BMI, physical activity, parity, smoking status, infertility, marital status, multivitamin use, and gestational diabetes. Results HDPs were reported in 1,089 (5.4%) pregnancies, of which 505 (2.5%) were PE. The DASH score (max points = 40) ranged from 16 to 32 points and the AHA score (max score = 50) ranged from 18 to 41 points in our population. Compared to women in the lowest quintile of adherence to the AHA, the RR (95%CI) of PE in quintiles 2, 3, 4, and 5 were 0.88 (0.68, 1.14), 0.87 (0.66, 1.15), 0.83 (0.64, 1.09), and 0.79 (0.60, 1.06), respectively (p-trend = 0.09). Similarly, the RR (95%CI) of PE among women in increasing quintiles of adherence to the DASH score was 0.88 (0.68, 1.13), 0.72 (0.55, 0.94), 0.80 (0.61, 1.05), and 0.62 (0.45, 0.84) compared to women in the lowest quintile (p-trend = 0.002). Conclusions Stronger pre-pregnancy adherence to the DASH dietary pattern was inversely associated to developing PE among participants of the NHS2. Funding Sources Supported by National Institutes of Health grants UM1-CA176726, P30-DK046200, U54-CA155626, and T32-DK007703-16.

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Is Acculturation Related to Obesity in Hispanic/Latino Adults? Results from the Hispanic Community Health Study/Study of Latinos

Journal of Obesity ◽

10.1155/2015/186276 ◽

2015 ◽

Vol 2015 ◽

pp. 1-8 ◽

Cited By ~ 47

Author(s):

Carmen R. Isasi ◽

Guadalupe X. Ayala ◽

Daniela Sotres-Alvarez ◽

Hala Madanat ◽

Frank Penedo ◽

...

Keyword(s):

Community Health ◽

Urban Areas ◽

Prolonged Exposure ◽

Health Study ◽

Extreme Obesity ◽

Standardized Protocol ◽

Hispanic Community ◽

The Us ◽

Prevalence Of Obesity ◽

Latino Adults

Background.The study examined the association of obesity with acculturation in a large and diverse sample of US Hispanic/Latino adults.Methods.The Hispanic Community Health Study (HCHS)/Study of Latinos (SOL) is a community-based cohort study of Hispanic/Latino adults aged 18–74 years (N=16,415) from four urban areas. Height and weight were directly measured using a standardized protocol. Acculturation was assessed by the Short Acculturation Scale for Hispanics (SASH). Other immigration related variables included place of birth, length of residency in the US, and age at immigration. Odds ratios were calculated to assess the association of overweight, moderate obesity, and extreme obesity (≥40 kg/m2) with acculturation and sociodemographic variables.Results.The prevalence of obesity was 42.4% for women and 36.5% for men and varied by field center and Hispanic/Latino background. The strongest predictor of moderate and extreme obesity was length of residency in mainland US. This association was consistent across Hispanic/Latino backgrounds. Acculturation was not significantly associated with obesity.Discussion.The burden of obesity is high among Hispanic/Latino adults. The study findings suggest that prolonged exposure to the environments in these communities, rather than acculturation, is an important risk factor for obesity in this population.

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