Follow-Up Of Quantiferon-TB Gold In Patients With Active Pulmonary Tuberculosis Or Extra-Pulmonary Tuberculosis Over Treatment Periods And The Usefulness Of Quantiferon-TB Gold

During the third year of MBBS program, we had a course of family health exercise in community medicine. This course was designed to produce competent family physicians; to enable us to understand the social, cultural, psychological, gender and economical aspects of illness, the interactions of ill persons with different members of the family and community health service, role of family members and family environment in patient care. It helped us to understand the natural history of the disease and importance of patient follow up. We were able to differentiate the nature of the problems while seeing the patients in the family from the nature of the same problems when the patient is seen in clinic or hospital. Here we present a follow-up of extra-pulmonary tuberculosis patient in our family health exercise during third year MBBS program.Journal of Gandaki Medical CollegeVolume, 09, Number 2, July December 2016, Page: 70-75

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Hybrid PET/MRI findings in a case of pulmonary and extra-pulmonary tuberculosis associated with motor-neuron disease-like illness—a coincidence or a causation?: a case report

Egyptian Journal of Radiology and Nuclear Medicine ◽

10.1186/s43055-020-00381-1 ◽

2021 ◽

Vol 52 (1) ◽

Author(s):

Sameer Peer ◽

Chandana Nagaraj ◽

Sandhya Mangalore

Keyword(s):

Pulmonary Tuberculosis ◽

Motor Neuron ◽

Motor Neuron Disease ◽

Lower Limbs ◽

Causative Role ◽

Extra Pulmonary Tuberculosis ◽

Tubercular Infection ◽

Extra Pulmonary ◽

Anti Tubercular Therapy

Abstract Background The association of tuberculosis and motor neuron disease-like illness has not been described previously. We present a case of co-existent pulmonary and extra-pulmonary tuberculosis in a young man whose clinical presentation was suggestive of a motor neuron disease-like illness and was subsequently diagnosed with tubercular infection. This case provokes our thought as to whether the association between tuberculosis and motor neuron dysfunction was just a co-incidence, given the high prevalence of tuberculosis in our set-up, or does it point towards a possible causative role of infection in motor neuron disease. Case presentation A 31-year-old man presented with progressive thinning of bilateral upper and lower limbs with associated pain and twitching sensation in upper and lower limb muscles. He had a history of loss of appetite and unintentional weight loss. On clinical examination, there was evidence of fasciculations in bilateral quadriceps, bilateral biceps, and paraspinal muscles which was further confirmed with electrophysiology. The work-up for underlying autoimmune, toxic and metabolic aetiology, and paraneoplastic aetiology was found to be negative. CT scan of the chest was suggestive of consolidations in bilateral upper lobes with multiple tree-in-bud nodules in both the lungs. Hybrid 18-Flourine-flourodeoxyglucose positron emission tomography and magnetic resonance imaging (F-18-FDG PET/MRI) imaging was also suggestive of pulmonary and extra-pulmonary tuberculosis. Imaging of the brain revealed atrophy along bilateral motor cortices with reduced tracer uptake. Diagnosis of tubercular infection was confirmed with nucleic acid amplification test and the patient was put on anti-tubercular therapy. On follow-up after 6 months, the patient reported improvement in the symptoms and the muscle power in bilateral upper and lower limbs. Conclusion We have described a very rare association of pulmonary and extra-pulmonary tuberculosis with motor neuron-like illness. It may be debated that such an association may just be co-incidental; however, given the improvement in the symptoms and signs of the motor neuron disease-like illness on follow-up while the patient was on anti-tubercular therapy, it may point towards a causative relationship between tubercular infection and motor neuron dysfunction. Further epidemiological studies should be sought for in order to reach a conclusive answer.

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Prevalence and treatment follow-up of drug-resistant extra-pulmonary tuberculosis in rural communities in Narshingdi, Bangladesh

International Journal of Advances in Medicine ◽

10.5455/2349-3933.ijam20140801 ◽

2014 ◽

Vol 1 (2) ◽

pp. 1 ◽

Cited By ~ 1

Author(s):

Hafsa Afroz ◽

Md Ali ◽

Md Fakruddin ◽

Kamrunnahar Kamrunnahar ◽

Suvamoy Datta

Keyword(s):

Rural Communities ◽

Pulmonary Tuberculosis ◽

Drug Resistant ◽

Extra Pulmonary Tuberculosis ◽

Extra Pulmonary

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Asymptomatic Isolated Cervical Tubercular Lymphadenopathy, How to Proceed?: A Case Series

Asian Journal of Medical Research ◽

10.47009/ajmr.2020.9.2.sg1 ◽

2020 ◽

Vol 9 (2) ◽

pp. 1-5

Author(s):

Ravi Singh Dogra ◽

Arjun Singh ◽

Vinay Bhardwaj ◽

Poonam ◽

Srijan Pandey ◽

...

Keyword(s):

Developing Countries ◽

Pulmonary Tuberculosis ◽

Case Series ◽

The Body ◽

Extra Pulmonary Tuberculosis ◽

Female Predominance ◽

Prevalent Disease ◽

Extra Pulmonary ◽

Tubercular Lymphadenitis

Tuberculosis is a highly prevalent disease in developing countries, the majority of cases are pulmonary and rest are extra-pulmonary. Cervical LN tuberculosis is one of the most common types of extra-pulmonary tuberculosis. Isolated cervical tubercular Lymphadenitis without accompanying pulmonary tuberculosis or another form of tuberculosis in the body is rare and, when present, requires thorough clinical examination and investigation. In the investigation of such patients, FNAC plays a major role, and aspirate should be tested for AFB through ZN stain and CBNAAT (PCR). Cervical tubercular Lymphadenitis is mainly a disease of young with a female predominance. All patients of cervical tubercular Lymphadenitis must receive antitubercular therapy with strict follow up for compliance and possible side effects from treatment.

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