scholarly journals Distinct Role of Transforming Growth Factor-Beta 1 and Fibroblast Growth Factors in Human Amelobastoma Epithelial Cell Proliferation

2017 ◽  
Vol 2 (1) ◽  
pp. 1
Author(s):  
Yuko Matsuda
Keyword(s):  
Cell Proliferation ◽  
Growth Factors ◽  
Transforming Growth Factor Beta ◽  
Transforming Growth Factor ◽  
Fibroblast Growth Factors ◽  
Fibroblast Growth ◽  
Epithelial Cell Proliferation ◽  
Growth Factor Beta ◽  
Distinct Role

scholarly journals Mesoderm and Jaw Development in Vertebrates: The Role of Growth Factors

1992 ◽  
Vol 4 (1) ◽  
pp. 73-91
Author(s):  
Nadine C. Milos
Keyword(s):  
Growth Factors ◽  
Growth Factor ◽  
Transforming Growth Factor Beta ◽  
Transforming Growth Factor ◽  
Developmental Sequence ◽  
Epithelial Growth Factor ◽  
Growth Factor Beta ◽  
Epithelial Growth ◽  
Jaw Development

The head and neck arise during development as the result of a complex series of cellular and molecular interactions that begin in the fertilized egg. In this article, the role of an important class of molecules, growth factors, is examined in two main steps of the developmental sequence: the initial induction of mesoderm and the later induction of jaw cartilage and bone. The article focuses particularly on the roles of members of the transforming growth factor-beta (TGF-β), fibroblast growth factor (FGF), and epithelial growth factor (EGF) families in these processes and current models of growth factor involvement. Possible experiments for the future are discussed.

Fibroblast growth factor and transforming growth factor beta repress transcription of the myogenic regulatory gene MyoD1

1989 ◽  
Vol 9 (8) ◽  
pp. 3576-3579
Author(s):  
T B Vaidya ◽  
S J Rhodes ◽  
E J Taparowsky ◽  
S F Konieczny
Keyword(s):  
Growth Factors ◽  
Growth Factor ◽  
Fibroblast Growth Factor ◽  
Transforming Growth Factor Beta ◽  
Transforming Growth Factor ◽  
Regulatory Gene ◽  
Fibroblast Growth ◽  
Regulatory Pathways ◽  
Growth Factor Beta

In this report, we demonstrate that myogenic cultures inhibited from differentiating by treatment with fibroblast growth factor or transforming growth factor beta show reduced levels of MyoD1 mRNA. Although this repression may contribute to the inhibition of myogenesis by growth factors, additional regulatory pathways must be affected, since inhibition still occurs in cultures engineered to constitutively express MyoD1 mRNA.

scholarly journals Fibroblast growth factor and transforming growth factor beta repress transcription of the myogenic regulatory gene MyoD1.

1989 ◽  
Vol 9 (8) ◽  
pp. 3576-3579 ◽  
Author(s):  
T B Vaidya ◽  
S J Rhodes ◽  
E J Taparowsky ◽  
S F Konieczny
Keyword(s):  
Growth Factors ◽  
Growth Factor ◽  
Fibroblast Growth Factor ◽  
Transforming Growth Factor Beta ◽  
Transforming Growth Factor ◽  
Regulatory Gene ◽  
Fibroblast Growth ◽  
Regulatory Pathways ◽  
Growth Factor Beta

In this report, we demonstrate that myogenic cultures inhibited from differentiating by treatment with fibroblast growth factor or transforming growth factor beta show reduced levels of MyoD1 mRNA. Although this repression may contribute to the inhibition of myogenesis by growth factors, additional regulatory pathways must be affected, since inhibition still occurs in cultures engineered to constitutively express MyoD1 mRNA.

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