Surface Modification of Titanium by Cobalt-Containing Plasma Electrolytic Oxidation Promotes Osteogenic Response

2021 ◽  
Vol 11 (8) ◽  
pp. 1524-1529
Author(s):  
Yang Qin ◽  
Quan-Ming Zhao ◽  
Xiao-Hui Ni ◽  
Shi Yin ◽  
Zhi-Gang Ma ◽  
...  

Titanium (Ti) is a widely used metallic biomaterial in developing orthopedic implants or devices, but it is often encountered with a poor osteogenic response. In this study, the authors report the surface modification of Ti with cobalt (Co)-containing titanium dioxide (TiO2) coatings by plasma oxidation technique in order to enhance its cellular response. The results were compared between unmodified and surface modified Ti. The scanning electron microscopy (SEM) analysis showed that the surface coating was homogenous and porous throughout the test specimen. Indeed, the energy-dispersive X-ray spectrometry (EDS) analysis showed that the cobalt was evenly distributed on the Ti surface. It was also observed from the preliminary cell culture studies that the surfacemodified Ti has excellent cell compatibility and has promoted the adhesion and proliferation of osteoblasts when compared to the unmodified Ti. The present study clearly demonstrated that the Co-containing plasma electrolytic oxidation is an efficient technique for the surface modification of Ti in order to promote its osteogenic response.

2017 ◽  
Vol 106 (2) ◽  
pp. 590-605 ◽  
Author(s):  
Muhammad Rizwan ◽  
Rodianah Alias ◽  
Umi Zhalilah Zaidi ◽  
Reza Mahmoodian ◽  
Mohd Hamdi

2016 ◽  
Vol 34 (1-2) ◽  
pp. 65-83 ◽  
Author(s):  
Sergey Vasilievich Gnedenkov ◽  
Yurii Petrovich Sharkeev ◽  
Sergey Leonidovich Sinebryukhov ◽  
Olga Alekseevna Khrisanfova ◽  
Elena Viktorovna Legostaeva ◽  
...  

AbstractMetallic implants have been successfully used in medicine for the past 60–70 years. Historically, implants were designed only as mechanical devices, whereas the biological aspects of their application were beyond the researchers’ interest. The improvement of living conditions and the increase of the average life span have changed the situation. The clinical requirements for medical implants rise up substantially. Presently, it seems impossible to imagine the use of metallic implants in the human body without preliminary surface modification to modulate the interaction between the surrounding biological environment and the implant. The review highlights the most recent advances in the field of functional coatings formed on implants by the plasma electrolytic oxidation technology. Special attention is dedicated to the principles of surface modification of the commercially pure titanium, titanium nickelide, and Mg-Mn-Ce magnesium alloy. The advantages and disadvantages of the method and the characteristics of these materials are discussed from this point of view. Some aspects of this review are aimed at corrosion protection of implants with application of polymer materials.


2014 ◽  
Vol 59 (1) ◽  
pp. 199-204 ◽  
Author(s):  
A. Krząkała ◽  
J. Młynski ◽  
G. Dercz ◽  
J. Michalska ◽  
A. Maciej ◽  
...  

Abstract Investigations on the surface modification of the Ti-6Al-4V alloy by plasma electrolytic oxidation are reported here. The oxidation process was carried out in a solution containing a zirconium silicate (ZrSiO4) suspension and sodium hydroxide (NaOH). Anodising was realised at voltages in a range from 100 V to 250 V. It was found that the morphology of the sample surface did not change during the oxidation of the alloy at 100 V. Application of voltages higher than 100 V led to the incorporation of zirconium silicate into the formed oxide layer and to significant changes of the surface morphology.


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