A Novel Disease Diagnosis Method Using Combining Knowledge Graph and Deep Learning

2021 ◽  
Vol 11 (7) ◽  
pp. 1845-1851
Author(s):  
Xi Cai

Disease diagnosis methods based on deep learning have some shortcomings in the auxiliary diagnosis process, such as relying heavily on labeled data and lack of doctor or expert experience knowledge. Based on the above background, this study proposes a disease diagnosis method combining medical knowledge atlas and deep learning (CKGDL). The core of the method is a knowledge-driven convolutional neural network (CNN) model. The structured disease knowledge in the medical knowledge map is obtained through entity link disambiguation and knowledge map embedding and extraction. The disease feature word vector and the corresponding knowledge entity vector in the disease description text are used as the multi-channel input of CNN, and different types of diseases are expressed from the semantic and knowledge levels in the convolution process. Through training and testing on multiple types of disease description text data sets, the experimental results show that the diagnostic performance of this method is better than that of a single CNN model and other disease diagnosis methods. And further verified that this method of joint training of knowledge and data is more suitable for the initial diagnosis of the disease.

Author(s):  
Mila Kwiatkowska ◽  
M. Stella Atkins ◽  
Les Matthews ◽  
Najib T. Ayas ◽  
C. Frank Ryan

This chapter describes how to integrate medical knowledge with purely inductive (data-driven) methods for the creation of clinical prediction rules. It addresses three issues: representation of medical knowledge, secondary analysis of medical data, and evaluation of automatically induced predictive models in the context of existing knowledge. To address the complexity of the domain knowledge, the authors have introduced a semio-fuzzy framework, which has its theoretical foundations in semiotics and fuzzy logic. This integrative framework has been applied to the creation of clinical prediction rules for the diagnosis of obstructive sleep apnea, a serious and under-diagnosed respiratory disorder. The authors use a semio-fuzzy approach (1) to construct a knowledge base for the definition of diagnostic criteria, predictors, and existing prediction rules; (2) to describe and analyze data sets used in the data mining process; and (3) to interpret the induced models in terms of confirmation, contradiction, and contribution to existing knowledge.


Information ◽  
2020 ◽  
Vol 11 (12) ◽  
pp. 556
Author(s):  
Weibo Song

The proper evaluation of heart health requires professional medical experience. Therefore, in clinical diagnosis practice, the development direction is to reduce the high dependence of the diagnosis process on medical experience and to more effectively improve the diagnosis efficiency and accuracy. Deep learning has made remarkable achievements in intelligent image analysis technology involved in the medical process. From the aspect of cardiac diagnosis, image analysis can extract more profound and abundant information than sequential electrocardiogram (ECG) signals. Therefore, a new region recognition and diagnosis method model of a two-dimensional ECG (2D-ECG) signal based on an image format is proposed. This method can identify and diagnose each refined waveform in the cardiac conduction cycle reflected in the image format ECG signal, so as to realize the rapid and accurate positioning and visualization of the target recognition area and finally get the analysis results of specific diseases. The test results show that compared with the results obtained by a one-dimensional sequential ECG signal, the proposed model has higher average diagnostic accuracy (98.94%) and can assist doctors in disease diagnosis with better visualization effect.


2021 ◽  
Vol 2050 (1) ◽  
pp. 012011
Author(s):  
Fuyou Zhao ◽  
Mingying Huo ◽  
Naiming Qi ◽  
Lianfeng Li ◽  
Weiwei Cui

Abstract A relatively perfect system for the fault diagnosis of mechanical and electrical products has been formed through decades of development. Nevertheless, the traditional fault diagnosis methods fail to cope with the gradual huge mechanical and electrical system. As a result, the advantages of fault diagnosis mode driven by data are increasingly prominent. Meanwhile, the effect of fault diagnosis has exceeded the traditional fault diagnosis methods in many fields. Through the use of the deep learning technology based on artificial intelligence, it carries out mapping and fitting. By fully taking advantages of neural network, it can effectively obtain the accurate classification of fault data. A fault diagnosis method based on the fault data of mechanical and electrical system is designed in this thesis. When it comes to the basic process, it is to take data sets for different mechanical and electrical products. Through the use of feature engineering method, it extracts the fault features of data. Through the use of deep learning technology, it carries out the intelligent diagnosis. According to the experimental results, it indicates that the fault diagnosis method based on deep learning technology can distinguish a variety of fault modes in mechanical and electrical system in an effective way. What’s more, good classification results in fault recognition have been achieved by a variety of deep convolutional neural network structures, so the feasibility of the method is further verified.


2021 ◽  
Vol 2021 ◽  
pp. 1-13
Author(s):  
Wanheng Liu ◽  
Ling Yin ◽  
Cong Wang ◽  
Fulin Liu ◽  
Zhiyu Ni

In this paper, a novel medical knowledge graph in Chinese approach applied in smart healthcare based on IoT and WoT is presented, using deep neural networks combined with self-attention to generate medical knowledge graph to make it more convenient for performing disease diagnosis and providing treatment advisement. Although great success has been made in the medical knowledge graph in recent studies, the issue of comprehensive medical knowledge graph in Chinese appropriate for telemedicine or mobile devices have been ignored. In our study, it is a working theory which is based on semantic mobile computing and deep learning. When several experiments have been carried out, it is demonstrated that it has better performance in generating various types of medical knowledge graph in Chinese, which is similar to that of the state-of-the-art. Also, it works well in the accuracy and comprehensive, which is much higher and highly consisted with the predictions of the theoretical model. It proves to be inspiring and encouraging that our work involving studies of medical knowledge graph in Chinese, which can stimulate the smart healthcare development.


Author(s):  
Xiaoping Zhao ◽  
Kaiyang Lv ◽  
Zhongyang Zhang ◽  
Yonghong Zhang ◽  
Yifei Wang

Abstract Edge computing equipment is a new tool that has been widely used to monitor the operation state of industrial equipment and to diagnose and analyze faults. Therefore, the fault diagnosis algorithm used in the edge computing device plays an especially significant role in fault diagnosis. The application of deep learning method in mechanical fault diagnosis has been gradually popularized, because it has many advantages, such as strong classification ability and accurate feature extraction ability. However, many of the completed papers and models are based on single label system and are used to diagnose single target fault. The validation set is not rigorous enough, and it is difficult to accurately simulate the faults that may occur in the actual production process. Nowadays, in the era of big data, the single label system ignores the joint relationship of different fault types, and it is difficult to make a correct judgment for the location, type and degree of mechanical failure. Hence, in the process of experiment, we used the bearing data of Case Western Reserve University(CWRU) to ensure the wide range and large quantity of data sets. A fault diagnosis method of gear and bearing in the gear-box based on multi-task deep learning model is put forward. In this method, gear and bearing faults can be diagnosed simultaneously. Through a separate task layer, this method can adaptively extract the characteristics of distinct targets from the same signal, and add a Batch Normalization layer(BN) to accelerate the convergence speed of the network. Through experiments, we conclude that it is an effective method which can judge the fault situation of gear and bearing accurately in a variety of working conditions.


2020 ◽  
Author(s):  
Pathikkumar Patel ◽  
Bhargav Lad ◽  
Jinan Fiaidhi

During the last few years, RNN models have been extensively used and they have proven to be better for sequence and text data. RNNs have achieved state-of-the-art performance levels in several applications such as text classification, sequence to sequence modelling and time series forecasting. In this article we will review different Machine Learning and Deep Learning based approaches for text data and look at the results obtained from these methods. This work also explores the use of transfer learning in NLP and how it affects the performance of models on a specific application of sentiment analysis.


2020 ◽  
Vol 15 ◽  
Author(s):  
Deeksha Saxena ◽  
Mohammed Haris Siddiqui ◽  
Rajnish Kumar

Background: Deep learning (DL) is an Artificial neural network-driven framework with multiple levels of representation for which non-linear modules combined in such a way that the levels of representation can be enhanced from lower to a much abstract level. Though DL is used widely in almost every field, it has largely brought a breakthrough in biological sciences as it is used in disease diagnosis and clinical trials. DL can be clubbed with machine learning, but at times both are used individually as well. DL seems to be a better platform than machine learning as the former does not require an intermediate feature extraction and works well with larger datasets. DL is one of the most discussed fields among the scientists and researchers these days for diagnosing and solving various biological problems. However, deep learning models need some improvisation and experimental validations to be more productive. Objective: To review the available DL models and datasets that are used in disease diagnosis. Methods: Available DL models and their applications in disease diagnosis were reviewed discussed and tabulated. Types of datasets and some of the popular disease related data sources for DL were highlighted. Results: We have analyzed the frequently used DL methods, data types and discussed some of the recent deep learning models used for solving different biological problems. Conclusion: The review presents useful insights about DL methods, data types, selection of DL models for the disease diagnosis.


Author(s):  
Kyungkoo Jun

Background & Objective: This paper proposes a Fourier transform inspired method to classify human activities from time series sensor data. Methods: Our method begins by decomposing 1D input signal into 2D patterns, which is motivated by the Fourier conversion. The decomposition is helped by Long Short-Term Memory (LSTM) which captures the temporal dependency from the signal and then produces encoded sequences. The sequences, once arranged into the 2D array, can represent the fingerprints of the signals. The benefit of such transformation is that we can exploit the recent advances of the deep learning models for the image classification such as Convolutional Neural Network (CNN). Results: The proposed model, as a result, is the combination of LSTM and CNN. We evaluate the model over two data sets. For the first data set, which is more standardized than the other, our model outperforms previous works or at least equal. In the case of the second data set, we devise the schemes to generate training and testing data by changing the parameters of the window size, the sliding size, and the labeling scheme. Conclusion: The evaluation results show that the accuracy is over 95% for some cases. We also analyze the effect of the parameters on the performance.


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