Physical Properties of High Functional Contact Lenses with Hydrophilic Substance and Graphene Oxide Nanocolloids

2020 ◽  
Vol 20 (8) ◽  
pp. 4860-4865
Author(s):  
Jae-Wuk Seok ◽  
A-Young Sung

The purpose of this experiment is to evaluate the physical properties of contact lenses made by adding hydrophilic Hyaluronic acid (HA) and Methacrylic acid (MA) as additives and Graphene oxide nanocolloids. As a contact lens, AIBN (Azobisisobutyronitrile) was used as an initiator with HEMA (2-hydroxy methyl methacrylate) and EGDMA (ethylene glycol dimethacrylate) as a cross-linker. Hyaluronic acid (HA) and methacrylic acid (MA) were added at 5%, respectively. Graphene oxide nanocolloids were added at 0.1%, 0.3% and 0.5%, respectively. Each prepared contact lens was hydrated in 99% NaCl saline solution for 24 hours. And the basic physical properties of contact lenses were evaluated and compared. The refractive index of the sample with hyaluronic acid and MA added was 1.4390, which was not significantly different from that of the basic combination contact lens sample. When Graphene oxide nanocolloids, a nanomaterial, were added, the refractive index decreased with increasing amount of Graphene oxide nanocolloids from 1.4209 to 13959. In the case of water content, the sample with 5% Hyaluronic acid and MA added slightly increased to 41.01%. In the case of Graphene oxide nanocolloids added, 48.76%~53.56% of Graphene oxide nanocolloids were added. Especially, it was observed that the water content increased sharply in the 0.1% sample of Graphene oxide nanocolloids. When the amount of graphene oxide nanocolloids added to the contact lens material was increased, the refractive index, which is a basic physical property, gradually decreased as the contact lens material was added together with Hyaluronic acid, MA, and Graphene oxide nanocolloids added as a nanomaterial. The water content tended to increase gradually. Therefore, the combination of Graphene oxide and hydrophilicmaterials shows a synergistic effect of physical properties, which is considered to be suitable as a material for contact lenses.

The Eye ◽  
2020 ◽  
Vol 22 (129) ◽  
pp. 44-46
Author(s):  
Mark Eddleston

Optimum Infinite is a new GP contact lens material, with an oxygen permeability of 180 barrer and was launched by Contamac at the GSLS 2019. This article provides an insight into the development and characteristics of this breakthrough material.


2021 ◽  
Vol 80 (1) ◽  
Author(s):  
Rekha Hansraj ◽  
Siddeeqa Jhetam ◽  
Jared Haridutt ◽  
Tymon Lahner ◽  
Sthabile Madlala ◽  
...  

Background: Contact lens care regimens appear to be prescribed based on familiarity or by matching contact lens brands rather than consideration to efficacy.Aim: This study compared the effectiveness of multipurpose and peroxide cleaning solutions on low- and high-water content ionic and non-ionic soft contact lenses, in removing Pseudomonas aeruginosa (P. aeruginosa).Setting: The laboratory work was conducted by health science students in a graduate level programme in the microbiology laboratory at a university in south-eastern South Africa.Methods: A quantitative analytical experimental design was used. Four groups (labelled I, II, III and IV) of soft contact lenses, varied ionicity and water content were inoculated with P. aeruginosa and then exposed to three solutions containing antimicrobial ingredients, polyaminopropyl biguanide (Dymed), hydrogen peroxide (H2O2) and polyquaternium-1 (Polyquad). Each group contained 14 soft contact lenses, with the exception of Group III in which eight lenses were used. Saline served as the control. After 18 h, the remaining colony-forming units were counted using visual inspection as an indicator of efficacy against P. aeruginosa.Results: The solution containing H2O2 was found to be the most effective in removing P. aeruginosa from all Food and Drug Administration (FDA) groups of contact lenses whilst Dymed was found to be comparatively ineffective for this organism. Water content and ionicity had no effect on the efficacy of the solutions.Conclusion: Practitioners should consider the efficacy of the active ingredients against microorganisms when dispensing contact lens solutions, particularly for contact lens wearers at risk for P. aeruginosa infections.


2021 ◽  
Vol 21 (9) ◽  
pp. 4625-4631
Author(s):  
Min-Jae Lee ◽  
A-Young Sung

This research was conducted to analyze the compatibility of used monomers and produce the high functional POSS-based ophthalmic polymer containing silicone monomers and neodymium nanoparticle. Synthesized silicone polymer (SiD), trimethylsilylmethacrylate (TSMA), N-vinyl-2-pyrrolidone (NVP) and neodymium nanoparticles were used as additives for the basic combination of polyhedral oligomeric silsesquioxane (POSS), and methyl methacrylate (DMA). And also, the materials were copolymerized with ethylene glycol dimethacrylate (EGDMA) as the cross-linking agent, azobisisobutyronitrile (AIBN) as the initiator. It is judged that the POSS-co-NVP polymer is optically good and thus have good compatibility. Especially copolymerization with TSMA showed high oxygen permeability, but with SID considered to be more stable judging by lens shape. Physical properties shows that the neodymium nanoparticle increases the wettability while maintaining water content. These materials are considered to make synergy effect each other, so it can be used in functional hydrogel ophthalmic lenses.


The Eye ◽  
2019 ◽  
Vol 127 (2019-3) ◽  
pp. 13-20 ◽  
Author(s):  
Alexander Myagkov ◽  
Elena Dyomina ◽  
Valery Forbes

Purpose: The purpose of the study is to determine the correlation between the incidence of giant papillary conjunctivitis induced by the use of contact lenses (CLPC) and contact lens material, replacement schedule or wearing time. The emergence of new materials and designs of contact lenses along with modifications in the replacement and wearing schedule have changed the structure of complications in users of soft contact lenses (SCLs). At present, infectious and hypoxic complications are extremely rare; on the other hand, toxic-allergic reactions that arise in users of contact lenses (CLs) have come to the fore. Material and methods. A retrospective cohort clinical study involved 1 668 users of SCL of various materials and with different replacement and wearing schedules. Patients were monitored from 2008 to 2018. Results. As a result of the study, it was found that the CLPC incidence correlate with the wearing time and replacement schedule of the SCLs.


2006 ◽  
Vol 26 (1) ◽  
pp. 57-64 ◽  
Author(s):  
Jose M. Gonzalez-Meijome ◽  
Madalena Lira ◽  
Antonio Lopez-Alemany ◽  
Jose B. Almeida ◽  
Manuel A. Parafita ◽  
...  

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