scholarly journals Epidemiology of contact lens-induced giant papillary conjunctivitis: a retrospective study

The Eye ◽  
2019 ◽  
Vol 127 (2019-3) ◽  
pp. 13-20 ◽  
Author(s):  
Alexander Myagkov ◽  
Elena Dyomina ◽  
Valery Forbes
Keyword(s):  
Contact Lens ◽  
Retrospective Cohort ◽  
Contact Lenses ◽  
The Other ◽  
Allergic Reactions ◽  
New Materials ◽  
Soft Contact ◽  
Soft Contact Lenses ◽  
Lens Material ◽  
Giant Papillary Conjunctivitis

Purpose: The purpose of the study is to determine the correlation between the incidence of giant papillary conjunctivitis induced by the use of contact lenses (CLPC) and contact lens material, replacement schedule or wearing time. The emergence of new materials and designs of contact lenses along with modifications in the replacement and wearing schedule have changed the structure of complications in users of soft contact lenses (SCLs). At present, infectious and hypoxic complications are extremely rare; on the other hand, toxic-allergic reactions that arise in users of contact lenses (CLs) have come to the fore. Material and methods. A retrospective cohort clinical study involved 1 668 users of SCL of various materials and with different replacement and wearing schedules. Patients were monitored from 2008 to 2018. Results. As a result of the study, it was found that the CLPC incidence correlate with the wearing time and replacement schedule of the SCLs.

scholarly journals The structure of soft contact lens users and the incidence of papillary conjunctivitis in the analyzed groups according to the data of “Krugozor” ophthalmology clinic

The Eye ◽  
2020 ◽  
Vol 22 (4(132)) ◽  
pp. 30-35
Author(s):  
O. V. Dubovtseva ◽  
N. A. Bakalova
Keyword(s):  
Contact Lens ◽  
Contact Lenses ◽  
Moderate Degree ◽  
Soft Contact ◽  
Wear Time ◽  
Soft Contact Lenses ◽  
Soft Contact Lens ◽  
Vision Correction ◽  
Lens Wear ◽  
Giant Papillary Conjunctivitis

Introduction. Vision correction by contact lenses is one of the most common and effective methods for correcting refractive errors in children and adults. Compliance with rules of soft contact lenses (SCLs) wearing is one of the most important conditions for a safe use, while violation of compliance is usually the main cause of complications.Purpose. To study the structure of contact lens wearers by ametropia and lens wearing time as well as to determine the relationship between the incidence of giant papillary conjunctivitis (GPC) with lens wear time and overwear time.Material and methods. A retrospective analysis of 1 000 records (1 000 patients) of patients who underwent vision correction by SCLs in “Krugozor” ophthalmology clinic in the year 2019 was carried out. Mean age of patients was 24.95 ± 8.62 years. Age, type and degree of ametropia, material (hydrogel, silicone hydrogel or biocompatible hydrogel), lens replacement schedule, presence of complications, lens overwear time and daily wear time were taken into account.Results. Most SCLs users are patients between 21 and 30 years old (47%) who have a moderate degree of ametropia (52%). Most of them (46%) preferred monthly replacement SCLs, 29% – bi-weekly replacement SCLs, 9% preferred daily replacement lenses, while quarterly replacement lenses were used by 16%. Only 26.9% of SCL users complied with the instructions for lens wear, while for 29.4% of them lens overwear time amounted to up to 14 days, for 34.1% – up to 28 days, and for 9.6% – more than 1 month. More than half (56%) of patients mainly wore SCLs during 16 hours a day, one in five (22.7%) used SCLs during 12 hours a day, and 12.6% – up to 20 hours a day. 8.7% wore lenses during up to 7 days. The incidence of GPC in patients who did not comply with replacement schedule and were overwearing lenses was significantly higher (38.71%) than in patients who followed the replacement schedule (3.21%).Conclusion. More than half of the users comprised young people with a moderate degree of myopia. The most commonly used SCLs were monthly replacement. It was discovered that only one in four wearers followed recommendations of manufacturers and replaced lenses on time. Lens overwear may lead to a development of a giant papillary conjunctivitis (GPC). 

scholarly journals Hydrogel Contact Lens for Extended Delivery of Ophthalmic Drugs

2011 ◽  
Vol 2011 ◽  
pp. 1-9 ◽  
Author(s):  
Xiaohong Hu ◽  
Lingyun Hao ◽  
Huaiqing Wang ◽  
Xiaoli Yang ◽  
Guojun Zhang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Contact Lens ◽  
Contact Lenses ◽  
Drug Carriers ◽  
Soft Contact ◽  
Soft Contact Lenses ◽  
Advantages And Disadvantages ◽  
Ophthalmic Drug Delivery ◽  
Ophthalmic Drug ◽  
Polymeric Hydrogels

Soft contact lenses can improve the bioavailability and prolong the residence time of drugs and, therefore, are ideal drug carriers for ophthalmic drug delivery. Hydrogels are the leading materials of soft contact lenses because of their biocompatibility and transparent characteristic. In order to increase the amount of load drug and to control their release at the expected intervals, many strategies are developed to modify the conventional contact lens as well as the novel hydrogel contact lenses that include (i) polymeric hydrogels with controlled hydrophilic/hydrophobic copolymer ratio; (ii) hydrogels for inclusion of drugs in a colloidal structure dispersed in the contact lenses; (iii) ligand-containing hydrogels; (iv) molecularly imprinted polymeric hydrogels; (v) hydrogel with the surface containing multilayer structure for drugs loading and releasing. The advantages and disadvantages of these strategies in modifying or designing hydrogel contact lenses for extended ophthalmic drug delivery are analyzed in this paper.

Cosmetics and Contact Lenses: Influence on Safety

The Eye ◽  
2021 ◽  
Vol 23 (3) ◽  
pp. 59-63
Author(s):  
S. V. Zimovets ◽  
A. Ya. Sverdlik
Keyword(s):  
Contact Lens ◽  
Contact Lenses ◽  
Cosmetic Products ◽  
Soft Contact ◽  
Dry Eyes ◽  
Soft Contact Lenses

The article describes the effect of decorative cosmetics on the material of soft contact lenses and studies specific features that can be observed in SCL wearers who use cosmetics extensively. Examples of complications associated with the use of various cosmetic products that may occur in contact lens wearers are given. Conclusion: in cases when patients have complaints about discomfort and dry eyes, doctors should pay attention to the amount of decorative cosmetics used as well as study the effect it can have on the surface of the contact lenses.

scholarly journals The impact of wearing single vision soft contact lenses on the peripheral refractive error

F1000Research ◽  
2016 ◽  
Vol 5 ◽  
pp. 2803
Author(s):  
Kareem Allinjawi ◽  
Sharanjeet-Kaur Sharanjeet-Kaur ◽  
Saadah Mohamed Akhir ◽  
Haliza Abdul Mutalib
Keyword(s):  
Visual Field ◽  
Open Field ◽  
Refractive Error ◽  
Contact Lens ◽  
Contact Lenses ◽  
Soft Contact ◽  
Soft Contact Lenses ◽  
Single Vision ◽  
The Right ◽  
The Impact

Aim: The purpose of this study was to determine the changes in the relative peripheral refractive error produced by soft single vision contact lenses in myopic schoolchildren. Methods: 27 myopic schoolchildren aged between 13 to 15 years were included in this study. The measurements of central and peripheral refraction were made only on the right eye using a Grand-Seiko WR-5100K open-field autorefractometer without contact lens (WL), and with wearing single vision contact lens (SVCL). Refractive power was measured at center and horizontal eccentricity between 35° temporal to 35° nasal visual field (in 5° steps). Results: SVCL showed an increase in peripheral hyperopic defocus at the nasal and temporal visual field compare with baseline, but this change was not statistically significant (p=0.129). Conclusion: Wearing single vision soft contact lenses increases the relative peripheral hyperopic defocus in myopic schoolchildren.

scholarly journals STUDY OF THE OPTICAL POWER OF NANOPHOTONIC SOFT CONTACT LENSES BASED ON POLY (2- HYDROXYETHYL METHACRYLATE) AND FULLERENE

2014 ◽  
Vol 5 (1) ◽  
Author(s):  
Aleksandra Debeljković Mitrović ◽  
Dragomir Stamenković ◽  
Manuel Conte ◽  
Božica Bojović ◽  
Spomenko Mihajlović
Keyword(s):  
Contact Lens ◽  
Contact Lenses ◽  
Measurement Techniques ◽  
Optical Power ◽  
Soft Contact ◽  
Standard Material ◽  
Soft Contact Lenses ◽  
Soft Contact Lens ◽  
Power Cylinder

In this paper results of comparative study of the optical power of soft contact lenses (SCL) made of standard material for SCL and nanophotonic materials with different measurement techniques used for the final contact lens controllers are presented. Three types of nanophotonic soft contact lenses were made of standard polymacon material (Soleko SP38TM) incorporated with fullerene C60, fullerol C60(OH)24 and fullerene metformin hydroxylate C60(OH)12(OC4N5H10)12. For the purposes of material characterization for potential application as soft contact lenses, the optical properties of the soft contact lenses were measured by Rotlex and Nidek device. With Rotlex device the following optical results were obtained: optical power and map of defects, while with the Nidek device: optical power, cylinder power and cylinder axis. The obtained values of optical power and map of defects showed that the optical power of synthesized nanophotonic soft contact lens is same to the nominal value, while this was not the case for the standard soft contact lens. Also, the quality of the nanophotonic soft contact lens is better than the standard one. Hence, it is possible to synthesize new nanophotonic soft contact lenses of desired optical characteristics, implying possibilities for their application in this field.

The Effect of Photoinitiator Concentration on the Physicochemical Properties of Hydrogel Contact Lenses

2014 ◽  
Vol 679 ◽  
pp. 118-127 ◽  
Author(s):  
Deirdre M. McElroy ◽  
Luke M. Geever ◽  
Clement L. Higginbotham ◽  
Sinead M. Devery
Keyword(s):  
Drug Delivery ◽  
Physicochemical Properties ◽  
Contact Lens ◽  
Contact Lenses ◽  
Delivery Systems ◽  
Eye Drops ◽  
Soft Contact ◽  
Soft Contact Lenses ◽  
Ophthalmic Drug Delivery ◽  
Ophthalmic Drug

Hydrogel soft contact lenses have been investigated as delivery systems for ophthalmic drug products in response to the need for more efficient ophthalmic drug delivery systems. Ocular drugs delivered via eye drops have a low residence time in the eye resulting in as low as 5% bioavailability of the therapeutic agent. This study investigates the effect of varying concentrations of the photoinitiator diphenyl (2,4,6-trimethylbenzoyl)-phosphine oxide (TPO) on the physicochemical properties of hydrogel soft contact lenses for ophthalmic drug delivery purposes. Contact lens samples were synthesised via photopolymerisation with a range of initiator concentration. Gel fraction and swelling results indicated that increasing the photoinitiator concentration increased the efficiency of the gel network and reduced the water content of contact lens samples. Fourier transform infra-red spectroscopy (FTIR) analysis was employed to confirm polymerisation of the lenses and also indicated the presence of residual photoinitiator in lenses with higher TPO concentrations.

Air Travel and Contact Lenses: A Laboratory Study

1988 ◽  
Vol 32 (6) ◽  
pp. 450-454
Author(s):  
Joseph E. Laviana ◽  
Frederick H. Rohles
Keyword(s):  
Relative Humidity ◽  
Contact Lenses ◽  
Flight Time ◽  
Air Travel ◽  
The Other ◽  
Laboratory Setting ◽  
Soft Contact ◽  
Soft Contact Lenses ◽  
Significant Difference ◽  
The Impact

The cabin of an inflight aircraft contains approximately 10% relative humidity (rh). To investigate the impact of this environment on eye comfort, an inflight humidity profile was simulated in a controlled laboratory setting. The experiment was replicated 3 times using a group of 4 subjects (2 males; 2 females) per test. Participants served in both control and experimental roles by wearing a hydrophilic contact lens on one eye and no lens on the other. Subjects provided evaluations of “eye comfort” for both eyes (contact and naked) at specified intervals during the 10 hour test. The results indicated that at 10% rh, there was no significant difference in eye comfort for either wearers or nonwearers of soft contact lenses. However, comfort decreased with the length of exposure (flight time), and for durations of six hours or longer a significant annoyance was reported.

scholarly journals Nonsurgical Procedures for Keratoconus Management

2017 ◽  
Vol 2017 ◽  
pp. 1-17 ◽  
Author(s):  
L. Rico-Del-Viejo ◽  
M. Garcia-Montero ◽  
J. L. Hernández-Verdejo ◽  
S. García-Lázaro ◽  
F. J. Gómez-Sanz ◽  
...  
Keyword(s):  
Contact Lens ◽  
Contact Lenses ◽  
Good Alternative ◽  
Lens System ◽  
Soft Contact ◽  
Visual Outcomes ◽  
Soft Contact Lenses ◽  
The Past ◽  
Contact Lens Fitting

Objectives. To describe the past 20 years’ correction modalities for keratoconus and their visual outcomes and possible complications.Methods. A review of the published literature related to the visual outcomes and possible complications in the context of keratoconus management using nonsurgical procedures for the last 20 years (glasses and contact lenses) was performed. Original articles that reported the outcome of any correction modalities of keratoconus management were reviewed.Results. The most nonsurgical procedure used on keratoconus management is the contact lens fitting. Soft contact lenses and soft toric contact lenses, rigid gas-permeable contact lenses, piggyback contact lens system, hybrid contact lenses, and scleral and corneoscleral contact lenses form the contemporary range of available lens types for keratoconus management with contact lenses. All of them try to restore the vision, improve the quality of life, and delay surgical procedures in patients with this disease. Complications are derived from the intolerance of using contact lens, and the use of each depends on keratoconus severity.Conclusions. In the context of nonsurgical procedures, the use of contact lenses for the management of keratoconic patients represents a good alternative to restore vision and improve the quality of live in this population.

scholarly journals Characterization of nanophotonic soft contact lenses based on poly (2-hydroxyethyl methacrylate) and fullerene

2013 ◽  
Vol 67 (6) ◽  
pp. 861-870 ◽  
Author(s):  
Aleksandra Debeljkovic ◽  
Lidija Matija ◽  
Djuro Koruga
Keyword(s):  
Contact Lens ◽  
Near Infrared ◽  
Contact Lenses ◽  
Base Material ◽  
Optical Power ◽  
Sem Analysis ◽  
Hydroxyethyl Methacrylate ◽  
Soft Contact ◽  
Soft Contact Lenses ◽  
Soft Contact Lens

This work presents comparative research of characteristics of a basic and new nanophotonic material, the latter of which was obtained by incorporation fullerene, C60, in the base material for soft contact lenses. The basic (SL38) and nanophotonic materials (SL38-A) for soft contact lenses were obtained by radical polymerization of 2-hydroxyethyl methacrylate and 2-hydroxyethyl methacrylate and fullerene, which were derived by the technology in the production lab of the company Soleko (Milan, Italy). The materials were used for production of soft contact lenses in the company Optix (Belgrade, Serbia) for the purposes of this research. Fullerene was used due to its apsorption transmission characteristics in ultraviolet, visible and near infrared spectrum. For the purposes of material characterization for potential application as soft contact lenses, network parameters were calculated and SEM analysis of the materials was performed while the optical properties of the soft contact lenses were measured by a Rotlex device. The values of the diffusion exponent, n, close to 0.5 indicated Fick's kinetics corresponding to diffusion. The investigated hydrogels could be classified as nonporous hydrogels. With Rotlex device, values of optical power and map of defects were showed. The obtained values of optical power and map of defects showed that the optical power of synthesized nanophotonic soft contact lens is identical to the nominal value while this was not the case for the basic lens. Also, the quality of the nanophotonic soft contact lens is better than the basic soft contact lens. Hence, it is possible to synthesize new nanophotonic soft contact lenses of desired optical characteristics, implying possibilities for their application in this field.

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