Optimum Infinite is a new era of oxygen permeability material for contact lenses

The Eye ◽  
2020 ◽  
Vol 22 (129) ◽  
pp. 44-46
Author(s):  
Mark Eddleston
Keyword(s):  
Contact Lens ◽  
Oxygen Permeability ◽  
Contact Lenses ◽  
New Era ◽  
Lens Material ◽  
Insight Into

Optimum Infinite is a new GP contact lens material, with an oxygen permeability of 180 barrer and was launched by Contamac at the GSLS 2019. This article provides an insight into the development and characteristics of this breakthrough material.

scholarly journals Pre-lens tear film evaluation scale: a tool for analyzing the tear film-lens interaction with respect to the material used

2012 ◽  
Vol 2 (1) ◽  
pp. 7
Author(s):  
Papagni Antonio ◽  
Rossella Fonte ◽  
Luca Benzoni
Keyword(s):  
Contact Lens ◽  
Contact Lenses ◽  
Tear Film ◽  
Patient Case ◽  
History Information ◽  
Eye Examination ◽  
The Relationship ◽  
Lens Surface ◽  
Insight Into

In clinical practice, to avoid or reduce the failure rate among users of contact lenses, it is necessary to obtain a detailed patient case history, information concerning symptoms, and a complete eye examination. In addition, application of an auxiliary photographic reference scale might increase the chances of improving initial success or, for existing contact lens wearers, provide insight into the extent or severity of symptoms. Patient symptoms are often directly related to contact lens failure, which in turn is related to the quality of the pre-corneal tear film as well as the <em>wettability</em> of the contact lens surface. We describe the relationship between the quality of the tear film, with particular attention to pre-contact lens tear film, variability in contact tolerance, and the material of which the contact lens is made.

Polyhedral Oligomeric Silsesquioxane Based Silicone Ophthalmic Contact Lens Material Containing Neodymium Nanoparticles

2021 ◽  
Vol 21 (9) ◽  
pp. 4625-4631
Author(s):  
Min-Jae Lee ◽  
A-Young Sung
Keyword(s):  
Ethylene Glycol ◽  
Physical Properties ◽  
Contact Lens ◽  
Oxygen Permeability ◽  
Polyhedral Oligomeric Silsesquioxane ◽  
Cross Linking ◽  
Synergy Effect ◽  
Glycol Dimethacrylate ◽  
Oligomeric Silsesquioxane ◽  
Lens Material

This research was conducted to analyze the compatibility of used monomers and produce the high functional POSS-based ophthalmic polymer containing silicone monomers and neodymium nanoparticle. Synthesized silicone polymer (SiD), trimethylsilylmethacrylate (TSMA), N-vinyl-2-pyrrolidone (NVP) and neodymium nanoparticles were used as additives for the basic combination of polyhedral oligomeric silsesquioxane (POSS), and methyl methacrylate (DMA). And also, the materials were copolymerized with ethylene glycol dimethacrylate (EGDMA) as the cross-linking agent, azobisisobutyronitrile (AIBN) as the initiator. It is judged that the POSS-co-NVP polymer is optically good and thus have good compatibility. Especially copolymerization with TSMA showed high oxygen permeability, but with SID considered to be more stable judging by lens shape. Physical properties shows that the neodymium nanoparticle increases the wettability while maintaining water content. These materials are considered to make synergy effect each other, so it can be used in functional hydrogel ophthalmic lenses.

Physical Properties of High Functional Contact Lenses with Hydrophilic Substance and Graphene Oxide Nanocolloids

2020 ◽  
Vol 20 (8) ◽  
pp. 4860-4865
Author(s):  
Jae-Wuk Seok ◽  
A-Young Sung
Keyword(s):  
Refractive Index ◽  
Graphene Oxide ◽  
Hyaluronic Acid ◽  
Physical Properties ◽  
Water Content ◽  
Methacrylic Acid ◽  
Contact Lens ◽  
Contact Lenses ◽  
Physical Property ◽  
Lens Material

The purpose of this experiment is to evaluate the physical properties of contact lenses made by adding hydrophilic Hyaluronic acid (HA) and Methacrylic acid (MA) as additives and Graphene oxide nanocolloids. As a contact lens, AIBN (Azobisisobutyronitrile) was used as an initiator with HEMA (2-hydroxy methyl methacrylate) and EGDMA (ethylene glycol dimethacrylate) as a cross-linker. Hyaluronic acid (HA) and methacrylic acid (MA) were added at 5%, respectively. Graphene oxide nanocolloids were added at 0.1%, 0.3% and 0.5%, respectively. Each prepared contact lens was hydrated in 99% NaCl saline solution for 24 hours. And the basic physical properties of contact lenses were evaluated and compared. The refractive index of the sample with hyaluronic acid and MA added was 1.4390, which was not significantly different from that of the basic combination contact lens sample. When Graphene oxide nanocolloids, a nanomaterial, were added, the refractive index decreased with increasing amount of Graphene oxide nanocolloids from 1.4209 to 13959. In the case of water content, the sample with 5% Hyaluronic acid and MA added slightly increased to 41.01%. In the case of Graphene oxide nanocolloids added, 48.76%~53.56% of Graphene oxide nanocolloids were added. Especially, it was observed that the water content increased sharply in the 0.1% sample of Graphene oxide nanocolloids. When the amount of graphene oxide nanocolloids added to the contact lens material was increased, the refractive index, which is a basic physical property, gradually decreased as the contact lens material was added together with Hyaluronic acid, MA, and Graphene oxide nanocolloids added as a nanomaterial. The water content tended to increase gradually. Therefore, the combination of Graphene oxide and hydrophilicmaterials shows a synergistic effect of physical properties, which is considered to be suitable as a material for contact lenses.

scholarly journals Epidemiology of contact lens-induced giant papillary conjunctivitis: a retrospective study

The Eye ◽  
2019 ◽  
Vol 127 (2019-3) ◽  
pp. 13-20 ◽  
Author(s):  
Alexander Myagkov ◽  
Elena Dyomina ◽  
Valery Forbes
Keyword(s):  
Contact Lens ◽  
Retrospective Cohort ◽  
Contact Lenses ◽  
The Other ◽  
Allergic Reactions ◽  
New Materials ◽  
Soft Contact ◽  
Soft Contact Lenses ◽  
Lens Material ◽  
Giant Papillary Conjunctivitis

Purpose: The purpose of the study is to determine the correlation between the incidence of giant papillary conjunctivitis induced by the use of contact lenses (CLPC) and contact lens material, replacement schedule or wearing time. The emergence of new materials and designs of contact lenses along with modifications in the replacement and wearing schedule have changed the structure of complications in users of soft contact lenses (SCLs). At present, infectious and hypoxic complications are extremely rare; on the other hand, toxic-allergic reactions that arise in users of contact lenses (CLs) have come to the fore. Material and methods. A retrospective cohort clinical study involved 1 668 users of SCL of various materials and with different replacement and wearing schedules. Patients were monitored from 2008 to 2018. Results. As a result of the study, it was found that the CLPC incidence correlate with the wearing time and replacement schedule of the SCLs.

Oxygen Permeability of a New Type of High Dk Soft Contact Lens Material

1998 ◽  
Vol 75 (1) ◽  
pp. 30-36 ◽  
Author(s):  
LARRY ALVORD ◽  
JOHN COURT ◽  
TONY DAVIS ◽  
COURTNEY F. MORGAN ◽  
KLAUS SCHINDHELM ◽  
...  
Keyword(s):  
Contact Lens ◽  
Oxygen Permeability ◽  
Soft Contact ◽  
Soft Contact Lens ◽  
New Type ◽  
Lens Material

scholarly journals Silver Nanoparticles as a Novel Potential Preventive Agent against Acanthamoeba Keratitis

Pathogens ◽  
2020 ◽  
Vol 9 (5) ◽  
pp. 350 ◽  
Author(s):  
Edyta B. Hendiger ◽  
Marcin Padzik ◽  
Ines Sifaoui ◽  
María Reyes-Batlle ◽  
Atteneri López-Arencibia ◽  
...  
Keyword(s):  
Silver Nanoparticles ◽  
Contact Lens ◽  
Contact Lenses ◽  
Acanthamoeba Keratitis ◽  
Primary Key ◽  
Specific Symptoms ◽  
Lens Material ◽  
And Storage ◽  
Lens Surface ◽  
Food And Drugs Administration

Free living, cosmopolitan amoebae from Acanthamoeba genus present a serious risk to human health. As facultative human parasites, these amoebae may cause Acanthamoeba keratitis (AK). Acanthamoeba keratitis is a severe, vision-threatening corneal infection with non-specific symptoms. The number of reported AK cases worldwide has been increasing every year. Moreover, 90% of Acanthamoeba keratitis cases are related to contact lens use. Wearing and storage contact lenses not in accordance with the physicians and manufacturers recommendations are the primary key risk factors of this disease. Amoebae can easily adhere to the contact lens surface and transmit to the corneal epithelium. Preventing amoebae adhesion to the contact lens surface could significantly decrease the number of AK infections. Until now, the effective therapy against AK is still under development. Currently proposed therapies are mainly limited to the chlorhexidine digluconate combined with propamidine isethionate or hexamidine applications, which are insufficient and very toxic to the eye. Due to lack of effective treatment, looking for new potential preventive agents is crucial to decrease the number of Acanthamoeba keratitis infections, especially among contact lens users. Nanoparticles have been already included in several novel therapies against bacteria, viruses, fungi, and protist. However, their anti-amoebic potential has not been fully tested yet. The aim of this study was to assess silver nanoparticles (AgNPs) and platinum nanoparticles (PtNPs) anti-amoebic activity and influence on the amoebae adhesion to the surface of four different groups of contact lenses—classified according to the Food and Drugs Administration (FDA) guidelines. The obtained results show that both tested nanoparticles were effective against Acanthamoeba trophozoites and decreased the amoebae adhesion to the contact lens surface. AgNPs showed better anti-amoebic activity to cytotoxicity dependence and reduced amoebae adhesion in a wider spectrum of the tested contact lenses. Our studies also confirmed that ionization next to hydration of the contact lens material is a crucial parameter influencing the Acanthamoeba adhesion to the contact lens surface. In conclusion, silver nanoparticles might be considered as a novel preventive agent against Acanthamoeba keratitis infection.

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