Ocular Growth in Premature Infants Conceived by In Vitro Fertilization versus Natural Conception

2005 ◽  
Vol 46 (4) ◽  
pp. 1163 ◽  
Author(s):  
Ruth Axer-Siegel ◽  
Dan Bourla ◽  
Lea Sirota ◽  
Dov Weinberger ◽  
Moshe Snir
2005 ◽  
Vol 58 (7-8) ◽  
pp. 375-379 ◽  
Author(s):  
Dunja Tabs ◽  
Tihomir Vejnovic ◽  
Nebojsa Radunovic

Women conceiving by assisted reproduction are at higher risk for preterm and premature rupture of membranes. The aim of our study was to estimate and compare incidence of preterm premature rupture of membranes in singleton pregnancies of women who conceived by intrauterine insemination and in vitro fertilization, from 1999 to 2003. We investigated 87 women from the intrauterine insemination, and 102 from the in vitro fertilization program. There were no statistically significant differences in regard to preterm and premature rupture of membranes: p>0.75 in two groups. The incidence of premature rupture of membranes was 2.30% (after intrauterine insemination) and 2.94% (after in vitro fertilization). There was no statistically significant differences in regard to preterm and premature rupture of membranes in women who conceived by insemination and in vitro fertilization. Estimated incidence of preterm and premature rupture of membranes was similar to the literature data and also similar to incidence after natural conception.


2019 ◽  
Vol 8 (4) ◽  
pp. 548 ◽  
Author(s):  
Agni Pantou ◽  
Mara Simopoulou ◽  
Konstantinos Sfakianoudis ◽  
Polina Giannelou ◽  
Anna Rapani ◽  
...  

The present study aims to explore the effectiveness of laparoscopic surgery on women presenting with infertility, of unidentified aetiology according to the standard infertility investigation, and recurrent failed In Vitro Fertilization (IVF) attempts. Identifying and correcting possible underlying pathologies by laparoscopy may subsequently enable natural conception in an effort to address infertility and avoid IVF overuse. One-hundred and seven (107) women with unidentified aetiology of infertility and recurrent failed IVF attempts met the inclusion criteria. Laparoscopic surgery was performed as the endpoint of the patients’ diagnostic journey, aiming to identify a possible underlying factor as the cause of infertility. Sixty-two (62) out of 107 patients (57.94%) that underwent laparoscopy were diagnosed with endometriosis, 25 out of the 107 patients (23.3%) were diagnosed with periadnixal and pelvic adhesions, and 20 cases (18.69%) presented with no pathology and remained unexplained. Following identification and correction of endometriosis and pelvic adhesions, patients were invited to conceive naturally. For the patients that laparoscopic investigation failed to reveal any pathology they were categorized as unexplained infertility and were subjected to a single IVF cycle. Natural conception success rate within the first postoperative year was the primary outcome. Within the first postoperative year, 30 out of 62 patients (48.38%) diagnosed with endometriosis following laparoscopic investigation achieved a natural conception, and 28 out of them (93.4%) reported live-births. Additionally, 11 out of 25 patients (44%) diagnosed with periadnixal and pelvic adhesions achieved natural conception within the first operative year. Regarding the group of unexplained infertility patients, only four out of the 20 patients (20%) achieved clinical pregnancy in the first post-operative IVF cycle. In conclusion, laparoscopy appears to be a promising approach, addressing infertility, providing significant diagnostic findings, while avoiding IVF overuse regarding patients of unidentified infertility presenting with recurrent failed IVF attempts.


2008 ◽  
Vol 90 (2) ◽  
pp. 289-296 ◽  
Author(s):  
Marjolein Knoester ◽  
Frans M. Helmerhorst ◽  
Jan P. Vandenbroucke ◽  
Lucette A.J. van der Westerlaken ◽  
Frans J. Walther ◽  
...  

2009 ◽  
Vol 64 (1) ◽  
pp. 18-19 ◽  
Author(s):  
Marjolein Knoester ◽  
Frans M. Helmerhorst ◽  
Jan P. Vandenbroucke ◽  
Lucette A. J. van der Westerlaken ◽  
Frans J. Walther ◽  
...  

2019 ◽  
Author(s):  
Jimeng Lao ◽  
Jianbo Mao ◽  
Chenyi Liu ◽  
Xueting Yu ◽  
Yirun Shao ◽  
...  

Abstract Background: To evaluate the effects of IVF on the development of the refractive system in premature infants from 36 weeks to 6 months of postmenstrual age. Methods: Premature infants were examined respectively at 36 weeks, 40 weeks, 44 weeks, 48 weeks, 52 weeks and 6 months of postmenstrual age. Spherical equivalent, biometric values and central corneal thickness were measured. These parameters were compared between premature infants conceived by IVF or naturally, and the relationship between these parameters were evaluated. Results: A total of 899 premature infants were recruited. Infants born by IVF had a higher rate of oxygen therapy than which in the NC group (P = 0.04). The multiple pregnancy ratio in the IVF group was 83.4%, significantly higher than which in the NC group (p<0.001). ROP developed in 126 of the 754 infants (16.7%) in the NC group and in 35 of the 145 (24.1%) infants in the IVF group (p=0.03). With the increase of PA, the ACD (r=0.67, p<0.0001), LT (r=0.19, p<0.0001), VT (r=0.80, p<0.0001) and AL (r=0.85, p<0.0001) increased while CCT (r=-0.39, p<0.0001) thinned. The refractive state had a hyperopic shift until 44 weeks of postmenstrual age (r=0.38, p<0.0001). then the mean dioptric value continuously declined by 6 months of PA (r=-0.32, p<0.0001). There was no statistically significant difference in these parameters between the NC group and IVF group (p>0.05). The percentage of ACD (r=0.326, p<0.0001) and VT (r=0.248, p<0.0001) in AL were positively correlated with PA, while the percentage of LT (r=-0.415, p<0.0001) in AL was negatively correlated with PA. Before 44 weeks of PA, SE was positively correlated with ACD (r=0.08, p<0.01) and AL (r=0.09, p<0.01). After 44 weeks of PA, it was negatively correlated with ACD (r=-0.23, p<0.0001), VT (r=-0.35, p<0.0001) and AL (r=-0.41, p<0.01). Conclusions: The percentage of ACD and VT in AL increased, the percentage of LT in AL decreased with the early ocular development. IVF does not affect ocular growth from 36 weeks to 6 months of PA.


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