scholarly journals Web-Based Reanalysis Intercomparison Tools (WRIT) for Analysis and Comparison of Reanalyses and Other Datasets

2014 ◽  
Vol 95 (11) ◽  
pp. 1671-1678 ◽  
Author(s):  
Catherine A. Smith ◽  
Gilbert P. Compo ◽  
Don K. Hooper
Keyword(s):  
Cross Sections ◽  
Climate Science ◽  
Data Access ◽  
Physical Sciences ◽  
Web Based ◽  
University Of Colorado ◽  
Standard Pressure ◽  
Climate Analysis ◽  
The University ◽  
Reanalysis Intercomparison

While atmospheric reanalysis datasets are widely used in climate science, many technical issues hinder comparing them to each other and to observations. The reanalysis fields are stored in diverse file architectures, data formats, and resolutions. Their metadata, such as variable name and units, can also differ. Individual users have to download the fields, convert them to a common format, store them locally, change variable names, regrid if needed, and convert units. Even if a dataset can be read via the Open-Source Project for a Network Data Access Protocol (commonly known as OPeNDAP) or a similar protocol, most of this work is still needed. All of these tasks take time, effort, and money. Our group at the Cooperative Institute for Research in the Environmental Sciences at the University of Colorado and affiliated colleagues at the NOAA's Earth System Research Laboratory Physical Sciences Division have expertise both in making reanalysis datasets available and in creating web-based climate analysis tools that have been widely used throughout the meteorological community. To overcome some of the obstacles in reanalysis intercomparison, we have created a set of web-based Reanalysis Intercomparison Tools (WRIT) at www.esrl.noaa.gov/psd/data/writ/. WRIT allows users to easily plot and compare reanalysis datasets, and to test hypotheses. For standard pressure-level and surface variables there are tools to plot trajectories, monthly mean maps and vertical cross sections, and monthly mean time series. Some observational datasets are also included. Users can refine date, statistics, and plotting options. WRIT also facilitates the mission of the Reanalyses.org website as a convenient toolkit for studying the reanalysis datasets.

scholarly journals Designing a Climate Service for Planning Climate Actions in Vulnerable Countries

Atmosphere ◽  
2021 ◽  
Vol 12 (1) ◽  
pp. 121
Author(s):  
Christiana Photiadou ◽  
Berit Arheimer ◽  
Thomas Bosshard ◽  
René Capell ◽  
Maria Elenius ◽  
...  
Keyword(s):  
Climate Science ◽  
Climate Impact ◽  
Climate Modelling ◽  
Climate Information ◽  
Climate Services ◽  
Web Based ◽  
Climate Service ◽  
Climate Analysis ◽  
International Experts ◽  
Active Interaction

The next generation of climate services needs not only tailoring to specific user needs but to provide, in addition, access to key information in a usable way that satisfies the needs of different users’ profiles; especially web-based services. Here, we present the outcomes from developing such a new interactive prototype. The service provides data for robust climate analysis to underpin decision-making when planning measures to compensate for climate impact. The goal is to facilitate the communication on climate information between climate modelling communities and adaptation or mitigation initiatives from vulnerable countries that are applying for funds from the Green Climate Fund (GCF). A participatory process was ensured during four workshops in four pilot countries, with an audience of national and international experts. During this process it was made clear that in all countries there is a strong need for knowledge in climate science, while in most countries there was also an increasing need of capacity in hydrological modelling and water management. The active interaction during the workshops was found necessary to facilitate the dialogue between service developers and users. Understanding the users, transparency on potentials and limitations of climate services together with capacity development in climate science and methods were required components in the development of the service.

scholarly journals The shaping of climate science: half a century in personal perspective

2015 ◽  
Vol 6 (2) ◽  
pp. 87-105 ◽  
Author(s):  
R. G. Barry
Keyword(s):  
Data Center ◽  
Climate Science ◽  
The Arctic ◽  
Personal Perspective ◽  
University Of Colorado ◽  
The Andes ◽  
History Of ◽  
The Uk ◽  
The University ◽  
Early Training

Abstract. The paper traces my career as a climatologist from the 1950s and that of most of my graduate students from the late 1960s. These decades were the formative ones in the evolution of climate science. Following a brief account of the history of climatology, a summary of my early training, my initial teaching and research in the UK is discussed. This is followed by new directions at the University of Colorado, Boulder from October 1968. The history of the World Data Center for Glaciology/National Snow and Ice Data Center in Boulder from 1977 is described and climate-cryosphere initiatives at the Cooperative Institute for Research in Environmental Sciences (CIRES). International activities and links are then reported, followed by a section on national and international committees. I then describe my activities during sabbaticals and research leaves. The paper concludes with discussion of my "retirement" activities and an epilogue. The paper is based on a lecture given at the Roger Barry Symposium: A Chronicle of Distinction: From the Arctic to the Andes, at the University of Colorado, 10 August 2004 and updated to 2014.

scholarly journals Observing and Thinking about the Atmosphere

2002 ◽  
Vol 27 (1) ◽  
pp. 1-20 ◽  
Author(s):  
Richard Goody
Keyword(s):  
World War Ii ◽  
Earth Science ◽  
National Research Council ◽  
Climate Science ◽  
The United States ◽  
Atmospheric Radiation ◽  
Physical Sciences ◽  
Research Activities ◽  
Earth’S Climate ◽  
The University

[Figure: see text] ▪ Abstract  FAUST: Ich fühl's, vergebens hab' ich alle Schätze Des Menschengeists auf mich herbeigerafft, Und wenn ich mich am Ende niedersetze, Quilt innerlich doch keine neue Kraft; Ich bin nicht um ein Haar breit höher, Bin dem Unendlichen nicht näher. Goethe's Faust, Part I, lines 1810–15. 1 A dedication to research in the physical sciences together with the circumstances of World War II, led me into theoretical and observational studies of the global physical climate. For all practical purposes, I was on my own when working in Cambridge and London, England, and I went whereever my interests led me. I organized three atmospheric observatories (two in England). I have also worked at many astronomical observatories. As time progressed, I became increasingly involved in studies of atmospheric radiation as a controlling factor for the Earth's climate. I am often taken to be a specialist in atmospheric radiation, but I have never regarded it as more than an important element in climate studies. But radiative transfer and global questions did not become important for climate science until later, and in the 1950s and 1960s I found myself drawn to studies of planetary atmospheres as an arena in which my skills were of central importance. Mars and Venus were the focus of my work for many years, and I was partly responsible for launching the Pioneer Venus mission, which placed probes into the Venus atmosphere in 1978. Much later, the experience I gained in space instrumentation and in the structure of atmospheres led me back to climate science, where I started. Then my interest was in observing the climate and testing the credibility of climate predictions. I still maintain some activity in this field. Outside these research activities, I created a Center for Earth and Planetary Physics at Harvard University to take over the activities of the Blue Hill Observatory, when that Observatory ceased to be a viable facility. The purpose of the Center was to teach earth science in the context of the discipline of physical science. The Center had some notable achievements but eventually had to give way to requirements for environmental sciences in the University, a change that I regret. During my active life in the United States, I invested a great deal of effort in support of the work of the National Research Council (NRC), including many years spent on report review. I am increasingly troubled by the postmodern view of science that appears to dominate these activities. But that may be no more than a biased rosy view of the past with its exciting early experiences and hopes.

scholarly journals Advances in Climate Analysis and Monitoring: Reflections on 40 Years of Climate Diagnostics and Prediction Workshops

2017 ◽  
Vol 98 (3) ◽  
pp. 461-471 ◽  
Author(s):  
C. F. Ropelewski ◽  
P. A. Arkin
Keyword(s):  
Data Analysis ◽  
Climate Variability ◽  
Numerical Models ◽  
Climate Science ◽  
Data Access ◽  
Climate Data ◽  
Physical Mechanisms ◽  
Single Station ◽  
Climate Analysis ◽  
Sophisticated Analysis

Abstract We examine the progress in the analysis of climate variability through the lens of a 40-year series of annual Climate Diagnostics and Prediction Workshops initiated by the National Oceanic and Atmospheric Administration (NOAA) in 1976. The evolution of climate data and data access, data analysis and display, and our understanding of the physical mechanisms associated with climate variability, as well as the evolution in the character of the workshops, are documented by reference to the series of workshop proceedings. This retrospective essay chronicles the transition from the mid-1970s, when individual investigators or their organizations held much of the climate data suitable for research, to the present day, where many of the key climate datasets are freely accessible on the Internet. In parallel we also chart the evolution in data analysis and display tools from hand-drawn line graphs of single-station data to color animations of regional and global fields based on satellite data, numerical models, and sophisticated analysis tools. Discussion of these two themes is augmented by documentation of the increasing understanding of the physical climate system as climate science moved away from the “bones of bare statistics” that characterized climate analysis in the mid–twentieth century toward the “flesh of physical understanding.”

The 1-MeV Electron Microscope Installation at the University of Colorado

1973 ◽  
Vol 31 ◽  
pp. 8-9 ◽  
Author(s):  
Mircea Fotino
Keyword(s):  
Electron Microscopy ◽  
Developmental Biology ◽  
Transmission Electron Microscopy ◽  
Electron Microscope ◽  
National Institutes Of Health ◽  
Experimental Program ◽  
University Of Colorado ◽  
Transmission Electron ◽  
The University ◽  
Research Resources

A new 1-MeV transmission electron microscope (Model JEM-1000) was installed at the Department of Molecular, Cellular and Developmental Biology of the University of Colorado in Boulder during the summer and fall of 1972 under the sponsorship of the Division of Research Resources of the National Institutes of Health. The installation was completed in October, 1972. It is installed primarily for the study of biological materials without many of the limitations hitherto unavoidable in standard transmission electron microscopy. Only the technical characteristics of the installation are briefly reviewed here. A more detailed discussion of the experimental program under way is being published elsewhere.

Discourse Mapping

2019 ◽  
Vol 2 (1) ◽  
Author(s):  
Joanna BOEHNERT
Keyword(s):  
Environmental Politics ◽  
Technology Policy ◽  
Policy Research ◽  
Mapping Method ◽  
Science And Technology Policy ◽  
Design Practice ◽  
Analysis Method ◽  
Environmental Sciences ◽  
University Of Colorado ◽  
The University

This workshop will create a space for discussion on environmental politics and its impact on design for sustainable transitions. It will help participants identify different sustainability discourses; create a space for reflection on how these discourses influence design practice; and consider the environmental and social implications of different discourses. The workshop will do this work by encouraging knowledge sharing, reflection and interpretative mapping in a participatory space where individuals will create their own discourse maps. This work is informed by my research “Mapping Climate Communication” conducted at the Centre for Science and Technology Policy Research (CSTPR) in the Cooperative Institute for Environmental Sciences (CIRES), the University of Colorado, Boulder. With this research project I developed a discourse mapping method based on the discourse analysis method of political scientists and sustainability scholars. Using my own work as an example, I will facilitate a process that will enable participants to create new discourse maps reflecting their own ideas and agendas.

Web-based Tools for Drug Repurposing: Successful Examples of Collaborative Research

2020 ◽  
Vol 28 (1) ◽  
pp. 181-195
Author(s):  
Quentin Vanhaelen
Keyword(s):  
User Interfaces ◽  
Collaborative Research ◽  
Meta Analysis ◽  
A Priori ◽  
Drug Repurposing ◽  
Data Access ◽  
Estimation Methods ◽  
Large Set ◽  
Computational Tools ◽  
Web Based

: Computational approaches have been proven to be complementary tools of interest in identifying potential candidates for drug repurposing. However, although the methods developed so far offer interesting opportunities and could contribute to solving issues faced by the pharmaceutical sector, they also come with their constraints. Indeed, specific challenges ranging from data access, standardization and integration to the implementation of reliable and coherent validation methods must be addressed to allow systematic use at a larger scale. In this mini-review, we cover computational tools recently developed for addressing some of these challenges. This includes specific databases providing accessibility to a large set of curated data with standardized annotations, web-based tools integrating flexible user interfaces to perform fast computational repurposing experiments and standardized datasets specifically annotated and balanced for validating new computational drug repurposing methods. Interestingly, these new databases combined with the increasing number of information about the outcomes of drug repurposing studies can be used to perform a meta-analysis to identify key properties associated with successful drug repurposing cases. This information could further be used to design estimation methods to compute a priori assessment of the repurposing possibilities.

scholarly journals Assessing Genetic Variants in Matched Biocompartments From Patients With Serous Ovarian Cancer

2021 ◽  
Vol 20 ◽  
pp. 153303382110279
Author(s):  
Brooke E. Sanders ◽  
Lisa Ku ◽  
Paul Walker ◽  
Benjamin G. Bitler
Keyword(s):  
Ovarian Cancer ◽  
Genetic Variants ◽  
Mutant Allele ◽  
Serous Ovarian Cancer ◽  
Brca Testing ◽  
Panel Testing ◽  
University Of Colorado ◽  
Gene Panel Testing ◽  
The University ◽  
Tumor Profiling

The clinical use of molecular tumor profiling (MTP) is expanding and there is an increasing use of MTP data to manage patient care. At the University of Colorado, 18 patients were diagnosed with primary serous ovarian cancer between 9/2015 and 6/2019 and consented for banking and analysis of tumor, ascites and plasma. All 18 patients had tumor and plasma samples that were sent for MTP, and 13 of 18 patients additionally had ascites collected and sent for MTP. 50-gene panel testing and BRCA testing were performed on primary tumor. BRCA genetic variants were more likely to be identified in plasma as compared to ascites or tumor, though not statistically significant ( P = 0.17). Co-occurring genetic variants between plasma and ascites were less common in comparison to co-occurring variants between tumor and plasma or tumor and ascites, though not statistically significant ( P = 0.68). Variants in KDR (VEGFR2) and TP53 were most likely to be conserved across all 3 biocompartments. Mutant allele frequencies (MAF) of individual genetic variants varied across biocompartments, though tended to be highest in the tumor, followed by ascites.

scholarly journals Towards Developing a Framework to Analyze the Qualities of the University Websites

Computers ◽  
2021 ◽  
Vol 10 (5) ◽  
pp. 57
Author(s):  
Maliha Rashida ◽  
Kawsarul Islam ◽  
A. S. M. Kayes ◽  
Mohammad Hammoudeh ◽  
Mohammad Shamsul Arefin ◽  
...  
Keyword(s):  
University Ranking ◽  
Web Based ◽  
Ranking Systems ◽  
Notice Board ◽  
Academic Websites ◽  
Multi Method Approach ◽  
The University ◽  
University Ranking Systems ◽  
Ranked List

The website of a university is considered to be a virtual gateway to provide primary resources to its stakeholders. It can play an indispensable role in disseminating information about a university to a variety of audience at a time. Thus, the quality of an academic website requires special attention to fulfil the users’ need. This paper presents a multi-method approach of quality assessment of the academic websites, in the context of universities of Bangladesh. We developed an automated web-based tool that can evaluate any academic website based on three criteria, which are as follows: content of information, loading time and overall performance. Content of information contains many sub criteria, such as university vision and mission, faculty information, notice board and so on. This tool can also perform comparative analysis among several academic websites and generate a ranked list of these. To the best of our knowledge, this is the very first initiative to develop an automated tool for accessing academic website quality in context of Bangladesh. Beside this, we have conducted a questionnaire-based statistical evaluation among several universities to obtain the respective users’ feedback about their academic websites. Then, a ranked list is generated based on the survey result that is almost similar to the ranked list got from the University ranking systems. This validates the effectiveness of our developed tool in accessing academic website.

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