Limited Support for the Efficacy of Nonpharmacological Treatments for the Core Symptoms of ADHD

2013 ◽  
Vol 170 (3) ◽  
pp. 241-244 ◽  
Author(s):  
Cathryn A. Galanter
Keyword(s):  
The Core ◽  
Limited Support ◽  
Core Symptoms ◽  
Nonpharmacological Treatments

Disorder-specific alterations of tactile sensitivity in neurodevelopmental disorders

2020 ◽  
Author(s):  
Jason He ◽  
Ericka Wodka ◽  
Mark Tommerdahl ◽  
Richard Edden ◽  
Mark Mikkelsen ◽  
...  
Keyword(s):  
Clinical Symptoms ◽  
Autism Spectrum ◽  
Typically Developing ◽  
Hyperactivity Disorder ◽  
The Core ◽  
Children With Asd ◽  
Tactile Detection ◽  
Spectrum Disorders ◽  
Sensory Processes ◽  
Core Symptoms

Alterations of tactile processing have long been identified in autism spectrum disorders (ASD) and attention-deficit/hyperactivity disorder (ADHD). However, the extent to which these alterations are disorder-specific, rather than disorder-general, and how they relate to the core symptoms of each disorder, remains unclear. We measured and compared tactile detection, discrimination and order judgment thresholds between a large sample of children with ASD, ADHD, ASD + ADHD combined and typically developing controls. The pattern of results suggested that while difficulties with tactile detection and order judgement were more common in children with ADHD, difficulties with tactile discrimination were more common in children with ASD. Strikingly, subsequent correlation analyses found that the disorder-specific alterations suggested by the group comparisons were also exclusively related to the core symptoms of each respective disorder. These results suggest that disorder-specific alterations of lower-level sensory processes exist and are specifically related to higher-level clinical symptoms of each disorder.

Self-monitoring in patients with schizophrenia

2004 ◽  
Vol 34 (8) ◽  
pp. 1561-1569 ◽  
Author(s):  
GÜNTHER KNOBLICH ◽  
FRANK STOTTMEISTER ◽  
TILO KIRCHER
Keyword(s):  
Hand Movements ◽  
Control Group ◽  
Formal Thought Disorder ◽  
Self Monitoring ◽  
The Core ◽  
Matched Healthy Control ◽  
Healthy Control ◽  
Dsm Iv ◽  
Core Symptoms ◽  
The Relationship

Background. The present study investigated whether a failure of self-monitoring contributes to core syndromes of schizophrenia.Method. Three groups of patients with a DSM-IV diagnosis of schizophrenia (n=27), with either prominent paranoid hallucinatory or disorganization syndrome, or without these symptoms, and a matched healthy control group (n=23) drew circles on a writing pad connected to a PC monitor. Subjects were instructed to continuously monitor the relationship between their hand movements and their visual consequences. They were asked to detect gain changes in the mapping. Self-monitoring ability and the ability to automatically correct movements were assessed.Results. Patients with either paranoid-hallucinatory syndrome or formal thought disorder were selectively impaired in their ability to detect a mismatch between a self-generated movement and its consequences, but not impaired in their ability to automatically compensate for the gain change.Conclusions. These results support the claim that a failure of self-monitoring may underlie the core symptoms of schizophrenia.

scholarly journals Health Care Trajectories for Children With ADHD in France: Results From the QUEST Survey

2016 ◽  
Vol 24 (1) ◽  
pp. 52-65 ◽  
Author(s):  
Hervé Caci ◽  
David Cohen ◽  
Olivier Bonnot ◽  
Bernard Kabuth ◽  
Jean-Phillipe Raynaud ◽  
...  
Keyword(s):  
Health Care ◽  
Health Care Professionals ◽  
National Sample ◽  
Adhd Diagnosis ◽  
Delay In Diagnosis ◽  
The Core ◽  
Initial Onset ◽  
Improvement Method ◽  
Core Symptoms ◽  
Improve Patient

Objective: The objective of this study is to retrospectively describe the pathway toward ADHD diagnosis and treatment, and identify potential areas for improvement. Method: Parent-reported questionnaires were collected by a national sample of ADHD specialists. Results: In total, 473 complete questionnaires were analyzed. Initial onset of ADHD symptoms was reported at a mean age of 4.45 years. Mean age at diagnosis was 8.07 years, and half of the families had seen at least three health care professionals previously. Psychiatrists were most commonly consulted. A “combined” (89% boys) and inattentive (49% boys) profile was identified. Diagnosis was made 1 year later for the latter group. Two thirds of patients received pharmacological treatment. The delay in diagnosis was identified as the main source of concern for caregivers. Conclusion: The 4-year delay in diagnosis may represent a loss of opportunity. Training health care professionals in the core symptoms of ADHD may help reduce disparities and improve patient trajectory.

scholarly journals Effects of different antidepressant treatments on the core of depression

2008 ◽  
Vol 10 (3) ◽  
pp. 309-320 ◽  
Keyword(s):  
Placebo Response ◽  
Severe Depression ◽  
Response Rates ◽  
Diagnostic Systems ◽  
Symptoms Of Depression ◽  
The Core ◽  
Antidepressant Treatments ◽  
Cognitive Disturbances ◽  
Clinical Consequences ◽  
Core Symptoms

Core symptoms of depression are a combination of psychological and somatic symptoms, often combined with psychomotor and cognitive disturbances. Diagnostic classification of depression including the concepts of melancholic, endogenous, or severe depression describe severely depressed patients suffering from most of the core symptoms, together with clinical characteristics of a cyclic unipolar or bipolar course, lower placebo response rates, higher response rates to electroconvulsive therapy, to antidepressant treatments with dually or mixed modes of action, or to lithium augmentation. Higher rates of hypothalamic-pituitary-adrenal axis hyperactivity and specific electroencephalographic patterns have also been shown in this patient group. Summarizing the symptomatology of depression in these patients, a broad overlap between the abovementioned subgroups can be suggested. Because the positive diagnosis of those core symptoms of depression may include clinical consequences, it would be of use to integrate all the mentioned concepts in the upcoming new versions of the diagnostic systems DSM-V and ICD-11.

Guidelines for treating depressive illness with antidepressants: A statement from the British Association for Psychopharmacology

1993 ◽  
Vol 7 (1_suppl) ◽  
pp. 19-23 ◽  
Author(s):  
Stuart A. Montgomery ◽  
P. Bebbington ◽  
P. Cowen ◽  
W. Deakin ◽  
P. Freeling ◽  
...  
Keyword(s):  
Side Effects ◽  
Depressed Mood ◽  
Antidepressant Treatment ◽  
Depressive Illness ◽  
Social Impairment ◽  
Self Blame ◽  
The Core ◽  
The Right ◽  
Therapeutic Doses ◽  
Core Symptoms

Depression is a common illness which affects some 3% of the population per year. At least 25% of those with marked depression do not consult their general practitioner and in half of those who do the illness is not detected. Depression is easy to recognize when four or five of the core symptoms have been present for 2 weeks which often coincides with some occupational and social impairment. The core symptoms are depressed mood, loss of interest or pleasure, loss of energy or fatigue, concentration difficulties, appetite disturbance, sleep disturbance, agitation or retardation, worthlessness or self blame and suicidal thoughts. A diagnosis of depression is made when five of these core symptoms, one of which should be depressed mood or loss of interest or pleasure, have been present for 2 weeks. Four core symptoms are probably sufficient. Response to antidepressants is good in those with more than mild symptoms. When there are only few or very mild depressive symptoms evidence of response to antidepressants is more uncertain. Antidepressants are effective, they are not addictive and do not lose efficacy with prolonged use. The newer antidepressants have fewer side effects than the older tricyclics, they are better tolerated and lead to less withdrawals from treatment. They are less cardiotoxic and are safer in overdose. Antidepressants should be used at full therapeutic doses. Treatment failure is often due to too low a dose being used in general practice. It may be difficult to reach the right dose with the older tricyclics because of side effects. To consolidate response, treatment should be continued for at least 4 months after the patient is apparently well. Stopping the treatment before this is ill-advised as the partially treated depression frequently returns. Most depression is recurrent. Long-term antidepressant treatment is effective in reducing the risk of new episodes of depression and should be continued to keep the patient well.

2. The modern era: Diagnosis and classification of depression

2017 ◽  
pp. 14-23
Author(s):  
Mary Jane Tacchi ◽  
Jan Scott
Keyword(s):  
Mental Disorders ◽  
Sigmund Freud ◽  
Sleep Problems ◽  
The Core ◽  
Current Thinking ◽  
Underlying Causes ◽  
Diagnosis And Classification ◽  
Core Symptoms ◽  
Modern Era

Although theories about the underlying causes of depression changed over the centuries, there was a remarkable level of consistency in the descriptions of the core symptoms with sadness and despondency accompanied by sleep problems and physical complaints. ‘The modern era: diagnosis and classification of depression’ reviews the contributions of Emil Kraepelin and Sigmund Freud to the current thinking on depression. Love them or loathe them, both men influenced thinking on the definition and boundaries of depression and how depression is diagnosed and classified. In more recent times, there have been international efforts to standardize approaches to diagnosis through the introduction of criterion-based classifications of mental disorders.

scholarly journals Baicalin regulates the dopamine system to control the core symptoms of ADHD

2019 ◽  
Vol 12 (1) ◽  
Author(s):  
Rongyi Zhou ◽  
Jiaojiao Wang ◽  
Xinmin Han ◽  
Bingxiang Ma ◽  
Haixia Yuan ◽  
...  
Keyword(s):  
Dopamine System ◽  
The Core ◽  
Core Symptoms
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