Age-Based Trends of Gastric Adenocarcinoma in the United States

2020 ◽  
pp. 000313482094739
Author(s):  
Denslow Trumbull ◽  
Riccardo Lemini ◽  
Enrique F. Elli ◽  
Sanjay P. Bagaria ◽  
Kristopher Attwood ◽  
...  

Background Recent studies have shown an increase in the incidence of gastric cancer (GC) among young adults in Asia and Latin America. However, it is unknown if a similar trend is happening in the United States (US). Methods A retrospective review of the National Cancer Data Base was conducted to identify patients diagnosed with gastric adenocarcinoma between the years of 2004 and 2013. Results A total of 93 734 patients were included. The 2 age groups below 40 did not see a change in GC incidence; however, age groups above 40 had increasing incidence. Patients aged 18-25 had the largest proportion of stage 4 disease and a poor survival (median 11.5 months), compared to older patients. Conclusion Despite the increasing trend of GC among individuals, the incidence of GC among young adults is not increasing. However, this subpopulation presents at more advanced stages (clinical stage 4) and thus has worse survival.

2020 ◽  
Vol 86 (5) ◽  
pp. 407-414
Author(s):  
Denslow Trumbull ◽  
Riccardo Lemini ◽  
Enrique F. Elli ◽  
Sanjay P. Bagaria ◽  
Kristopher Attwood ◽  
...  

Background Recent studies have shown an increase in the incidence of gastric cancer (GC) among young adults in Asia and Latin America. However, it is unknown if a similar trend is happening in the United States. Methods A retrospective review of the National Cancer Database was conducted to identify patients diagnosed with gastric adenocarcinoma between the years of 2004 and 2013. Results A total of 93 734 patients were included. The two age groups below 40 did not see a change in GC incidence; however, age groups above 40 had increasing incidence. Patients aged 18 to 25 had the largest proportion of stage 4 disease and a poor survival (median 11.5 months), compared to older patients. Conclusion Despite the increasing trend of GC among individuals, the incidence of GC among young adults is not increasing. However, this subpopulation presents at more advanced stages (clinical stage 4) and thus has worse survival.


2007 ◽  
Vol 11 (4) ◽  
pp. 410-420 ◽  
Author(s):  
Kaye M. Reid-Lombardo ◽  
Greer Gay ◽  
Lina Patel-Parekh ◽  
Jaffer A. Ajani ◽  
John H. Donohue ◽  
...  

2019 ◽  
Vol 94 (8) ◽  
pp. 1467-1474 ◽  
Author(s):  
Aref Al-Kali ◽  
Darci Zblewski ◽  
James M. Foran ◽  
Mrinal S. Patnaik ◽  
Beth R. Larrabee ◽  
...  

2014 ◽  
Vol 191 (4S) ◽  
Author(s):  
Claudio Jeldres ◽  
Craig R. Nichols ◽  
Khanh Pham ◽  
Sia Daneshmand ◽  
Christian Kollmannsberger ◽  
...  

Cancer ◽  
1998 ◽  
Vol 83 (6) ◽  
pp. 1262-1273 ◽  
Author(s):  
Kirby I. Bland ◽  
Herman R. Menck ◽  
Carol E. H. Scott-Conner ◽  
Monica Morrow ◽  
David J. Winchester ◽  
...  

2017 ◽  
Vol 83 (6) ◽  
pp. 640-647 ◽  
Author(s):  
Emmanuel Gabriel ◽  
Katherine Ostapoff ◽  
Kristopher Attwood ◽  
Eisar Al-Sukhni ◽  
Patrick Boland ◽  
...  

The incidence of colorectal cancer (CRC) among Americans under the age of 50 years is increasing. The purpose of this study was to identify racial and socioeconomic disparities associated with this trend. The National Cancer Data Base was used to identify patients with CRC from 1998 to 2011. Patients were stratified by age (<50 versus >60 years), with ages 50 to 60 years omitted from the analysis to minimize overlapping trends between the two age groups. Relative frequencies (RFs) by year were plotted against demographic variables. Changes in RF over time and intervals from diagnosis to treatment (including surgery and chemotherapy) were compared. A total of 1,213,192 patients were studied; 885,510 patients with colon cancer and 327,682 with rectal or rectosigmoid cancer. Patients <50 years had higher RF for stage III/IV CRC compared with >60 years, with the highest rate of increase in stage III colon cancer (0.198% per year). Patients <50 years had higher RF for CRC if they were African-American or Hispanic. Hispanic patients <50 years had the highest rates of increase for both colon (RF = 0.300% per year) and rectal cancer (RF = 0.248% per year). Compared with race, other variables including education and income were not found to have as strong an association on age-related rates of CRC. No clinically significant differences were observed for time from diagnosis to treatment in either age group. Important racial disparities are associated with differences in age-related CRC rates, warranting further investigation to develop improved strategies for the earlier detection of CRC in these populations.


2019 ◽  
Vol 21 (Supplement_6) ◽  
pp. vi211-vi211
Author(s):  
Shearwood McClelland III ◽  
Catherine Degnin ◽  
Yiyi Chen ◽  
Gordon Watson ◽  
Jerry Jaboin

Abstract INTRODUCTION For brain metastases, single-fraction stereotactic radiosurgery (SRS) spares appropriately chosen patients from the invasiveness of operative intervention and the permanent cognitive morbidity of whole brain radiation. SRS is delivered predominantly via two modalities: Gamma Knife, and linear accelerator (LINAC). The implementation of the American Tax Payer Relief Act (ATRA) in 2013 represented the first time limitations specifically targeting SRS reimbursement were introduced into federal law. The subsequent impact of the ATRA on SRS utilization in the United States (US) has yet to be examined. METHODS The National Cancer Data Base (NCDB) from 2010–2016 identified brain metastases patients from non-small cell lung cancer (NSCLC) throughout the US having undergone SRS. Utilization between GKRS and LINAC was assessed before (2010–2012) versus after (2013–2016) ATRA implementation. Utilization was adjusted for several variables, including patient demographics and healthcare system characteristics. RESULTS From 2012 to 2013, there was a substantial decrease of LINAC SRS in favor of GKRS overall (37% to 28%) and individually in both academic and non-academic centers. Over the three-year span immediately preceding ATRA implementation, 65.8% received GKRS and the remaining 34.2% receiving LINAC. In the four years immediately following ATRA implementation 68.0% received GKRS compared with 32% receiving LINAC; these differences were not statistically significant. CONCLUSIONS ATRA implementation in 2013 caused an initial spike in Gamma Knife SRS utilization, followed by a steady decline, similar to rates prior to implementation. These findings are indicative that the ATRA provision mandating Medicare reduction of outpatient payment rates for Gamma Knife to be equivalent with those of LINAC SRS had a significant short-term impact on the radiosurgical treatment of metastatic brain disease throughout the US. Such findings should serve as a reminder of the importance and impact of public policy on treatment modality utilization by physicians and hospitals.


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