The Effect of Perianal Tramadol Infiltration on Postoperative Pain Following Hemorrhoidectomy

2020 ◽  
pp. 000313482098168
Author(s):  
Maryam Hatami ◽  
Mohammad Talebi ◽  
Naimeh Heiranizadeh ◽  
Sedighe Vaziribozorg
Keyword(s):  
Postoperative Pain ◽  
Pain Score ◽  
Postoperative Nausea And Vomiting ◽  
Nausea And Vomiting ◽  
Topical Anesthetic ◽  
Double Blind ◽  
Double Blind Clinical Trial ◽  
Significant Difference ◽  
Duration Of Surgery ◽  
Grade 3

Introduction The present study was attempted to evaluate the effect of perianal infiltration of tramadol on postoperative pain in patients undergoing hemorrhoidectomy. Method This double-blind clinical trial study was carried out on 90 patients with grade 3 and 4 hemorrhoids undergoing hemorrhoidectomy. Patients were randomly assigned into 3 groups of control or bupivacaine or tramadol. Before the surgery, perianal infiltration of .25% bupivacaine or tramadol or normal saline was prescribed to each group, respectively. Data on pain severity (based on the visual analog scale (VAS), the duration of surgery, sedation score, pain at the first defecation, first request time for additional analgesia, nausea and vomiting, and analgesic intakes) were evaluated and analyzed. Results Duration of surgery was almost similar in all 3 groups ( P = .974). The results showed a significant difference in pain score between 3 groups ( P ≤.05) at all times after the surgery. In addition, the means of sedation scores ( P = .03), pain score at the first defecation ( P = .001), the time to first analgesic request ( P = .001), and ketorolac administration times ( P = .01) were significantly different between 3 groups. Finally, no complication was reported regarding postoperative nausea and vomiting. Conclusion Given the notable efficacy of tramadol in reducing pain after hemorrhoidectomy and its minor side effects, this medication is suggested as an effective topical anesthetic to decrease pain after hemorrhoidectomy.

scholarly journals Effect of Supplemental Perioperative Oxygen 80% in Postoperative Nausea and Vomiting in Patients Undergoing Cataract Surgery

2019 ◽  
Author(s):  
Aliakbar Keykha ◽  
Mahshid Ashrafzadeh ◽  
Alireza Rahat Dahmardeh ◽  
Bibi Mahdie Khodadadi Hosseini
Keyword(s):  
Cataract Surgery ◽  
Incidence Rate ◽  
Postoperative Nausea ◽  
Postoperative Nausea And Vomiting ◽  
Supplemental Oxygen ◽  
Nausea And Vomiting ◽  
Chi Square ◽  
Double Blind ◽  
Double Blind Clinical Trial ◽  
Significant Difference

Background: Postoperative nausea and vomiting (PONV) leads to an increase in intraocular pressure (IOP) and its side effects, which should be controlled using the least complicated method. Therefore, the purpose of this study was to evaluate the effect of 80% supplemental perioperative oxygen on PONV in patients undergoing cataract surgery. Methods: The present double-blind clinical trial was conducted on 201 patients undergoing cataract surgery. The subjects were selected by convenience sampling method and randomly divided into two groups of oxygen 30% administration and oxygen 80% administration. The operation of patients was performed with the same surgical procedure and team. After the operation, the incidence rate of PONV was recorded in both groups and compared along with other variables by SPSS software using descriptive statistics and chi-square. Results: There was no significant difference in age and sex between the two groups. The incidence rate of PONV was high in both groups, with statistically significant higher value in the group with 30% supplemental oxygen compared to the group with 80% supplemental oxygen (p=0.000). Conclusion: The use of 80% perioperative oxygen concentration could reduce the PONV severity

scholarly journals Granisetron versus Granisetron-Dexamethasone for Prevention of Postoperative Nausea and Vomiting in Pediatric Strabismus Surgery: A Randomized Double-Blind Trial

2016 ◽  
Vol 2016 ◽  
pp. 1-6 ◽  
Author(s):  
Renu Sinha ◽  
Dilip Shende ◽  
Souvik Maitra ◽  
Neeraj Kumar ◽  
Bikash Ranjan Ray ◽  
...  
Keyword(s):  
Postoperative Nausea ◽  
Postoperative Nausea And Vomiting ◽  
Complete Response ◽  
Strabismus Surgery ◽  
Nausea And Vomiting ◽  
Fisher Exact Test ◽  
Double Blind ◽  
Exact Test ◽  
Oculocardiac Reflex ◽  
Significant Difference

Aim.Efficacy of granisetron and combination of granisetron and dexamethasone was evaluated for prevention of postoperative nausea and vomiting (PONV) in children undergoing elective strabismus surgery.Methods.A total of 136 children (1–15 years) were included. Children received either granisetron (40 mcg/kg) [group G] or combination of granisetron (40 mcg/kg) and dexamethasone (150 mcg/kg) [group GD]. Intraoperative fentanyl requirement and incidence and severity of oculocardiac reflex were assessed. PONV severity was assessed for first 24 hours and if score was >2, it was treated with metoclopramide. Postoperative analgesia was administered with intravenous fentanyl and ibuprofen.Results.The demographic profile, muscles operated, and fentanyl requirement were comparable. Complete response to PONV in first 24 hours was observed in 75% (51/68) of children in group G and 76.9% (50/65) of children in group GD, which was comparable statistically (p=0.96, Fisher exact test; OR 1.11, 95% CI 0.50, 2.46). Incidence of PONV between 0 and 24 hours was comparable. One child in group G required rescue antiemetic in first 24 hours and none of the children had severe PONV in group GD. There was no significant difference in incidence or severity of oculocardiac reflex.Conclusion.Dexamethasone did not increase efficacy of granisetron for prevention of PONV in elective pediatric strabismus surgery. Registration number of clinical trial wasCTRI/2009/091/001000.

scholarly journals Preoperative Fasting Abbreviation and its Effects on Postoperative Nausea and Vomiting Incidence in Gynecological Surgery Patients

2020 ◽  
Vol 42 (08) ◽  
pp. 468-475
Author(s):  
Gisele Vissoci Marquini ◽  
Francisco Edes da Silva Pinheiro ◽  
Alfredo Urbano da Costa Vieira ◽  
Rogério Melo da Costa Pinto ◽  
Maria Gabriela Baumgarten Kuster Uyeda ◽  
...  
Keyword(s):  
At Risk ◽  
Postoperative Nausea ◽  
Randomized Study ◽  
Postoperative Nausea And Vomiting ◽  
Nausea And Vomiting ◽  
Control Group ◽  
Gynecological Surgery ◽  
Preoperative Fasting ◽  
Double Blind ◽  
Significant Difference

Abstract Objective To investigate the effects of preoperative fasting abbreviation with a carbohydrate and protein-enriched solution, on postoperative nausea and vomiting (PONV) incidence in gynecological surgery patients, a population naturally at risk for such unpleasant episodes. Methods The present prospective double-blind randomized study was performed at The Hospital Municipal e Maternidade Dr. Odelmo Leão Carneiro (HMMOLC, in the Portuguese acronym), in Uberlândia, state of Minas Gerais, Brazil, in partnership with the Gynecology Department of the Universidade Federal de São Paulo (UNIFESP), approved by the Human Research Ethics Committee of UNIFESP and the board of HMMOLC, and included in the Brazil Platform and in the Brazilian Clinical Trial Registry. After signing the consent form, 80 women, who were submitted to gynecological surgery in the period from January to June 2016, were randomized into 2 groups: control group (n = 42) and juice group (n = 38). They received, respectively, 200 mL of inert solution or liquid enriched with carbohydrate and protein 4 hours presurgery. The incidence, frequency and intensity of PONV were studied using the Visual Analogue Scale (VAS), with statistical analysis performed by the software IBM SPSS Statistics for Windows, Version 20.0 (IBM Corp, Armonk, NY, USA). Results The incidence of nausea and vomiting was lower than in the literature, to this population, with 18.9% (14/74) for the control group and 10.8% (8/74) for the juice group, respectively, with no statistically significant difference between the groups. Conclusion The incidence of nausea and vomiting was lower than in the literature, but it cannot be said that this is due to the abbreviation of fasting. It can provide greater comfort, with the possibility of PONV prevention in patients at risk for these episodes.

scholarly journals Laser hemorrhoidoplasty versus Milligan-Morgan hemorrhoidectomy - short term outcome

2019 ◽  
Vol 76 (1) ◽  
pp. 8-12
Author(s):  
Halit Maloku ◽  
Ranko Lazovic ◽  
Hasime Terziqi
Keyword(s):  
Postoperative Pain ◽  
Hemorrhoidal Disease ◽  
Arterial Blood Flow ◽  
Term Outcome ◽  
Arterial Blood ◽  
Venous Dilatation ◽  
Surgical Methods ◽  
Significant Difference ◽  
Duration Of Surgery ◽  
Grade 3

Background/Aim. According to the ?vascular? theory, arterial inflow into the upper hemorrhoidal artery leads to venous dilatation of the hemorrhoidal plexus. Laser hemorrhoidoplasty (LHP) is a new treatment applied to outpatients in whom the hemorrhoid arterial blood flow is coagulated (nourishes by hemorrhoidal plexus) by laser. The aim of this study was to compare two groups of patients treated by two different methods: by laser (LHP) and with open surgical procedure ? the Milligan Morgan (MM) method. Methods. This study included 200 patients with grade 3 hemorrhoidal disease older than 18 years, divided into two groups: 100 patients treated with the LHP, while the other 100 patients with the MM hemorrhoidectomy. Parameters used to compare two applied surgical methods were: duration of hospitalization, postoperative pain, the presence of bleeding and time needed to return to normal life. Results. The results reveal a statistically significant difference between these two methods. The level of postoperative pain was lower in the group of patients treated with the LHP compared to the group of patients treated with the MM method (p < 0.0001). The group treated with the LHP manifested less bleeding in comparison with the group treated with the open surgical method (MM). Length of hospitalization and duration of surgery were significantly shorter in the group treated with the LHP method than in the group treated by the MM method. Conclusion. According to our results, it is clear that the LHP method has many advantages over the MM hemorrhoidectomy in patients with grade 3 hemorrhoidal disease.

scholarly journals Comparison of Pain Score and Complications Following Acetaminophen and Pethidine Injection During Vaginal Delivery: A Double-blind Clinical Trial

2021 ◽  
Vol 36 (2) ◽  
pp. e250-e250
Author(s):  
Masoumeh Mirteimouri ◽  
Leila Pourali ◽  
Mozhgan Soltani ◽  
Maryam Salehi ◽  
Atiyeh Vatanchi ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Pain Score ◽  
Vaginal Delivery ◽  
Labor Pain ◽  
Maternal Complications ◽  
Double Blind ◽  
Neonatal Complications ◽  
Double Blind Clinical Trial ◽  
Significant Difference ◽  
Intravenous Acetaminophen

Objectives: Recently, intravenous acetaminophen has been introduced as an intervention with analgesic potential similar to that of opioid analgesics in labor pain management. This study aimed to compare the pain score and maternal and neonatal complications following acetaminophen and pethidine injections during vaginal delivery. Methods: This randomized, double-blind clinical trial was conducted on pregnant women during the first stage of delivery referred to Ghaem and Omolbanin Hospitals in Mashhad, Iran, from March to December 2017. The subjects were assigned randomly to one of two groups: acetaminophen and pethidine. The pain intensity was measured before and 15, 60, 120, 180, and 240 minutes after injection. Results: The pain score and pain score changes showed no significant difference between the two groups at different times. The incidence of maternal complications during delivery and the first hour after delivery was not statistically significant between the two groups, but 15 minutes after injection, vomiting (p = 0.001), nausea (p = 0.001), and dizziness (p = 0.001) were significantly higher in the pethidine group. The mean one and five minutes Apgar scores were significantly higher in the acetaminophen group. Conclusions: Intravenous acetaminophen led to fewer maternal complications than pethidine, especially during the first 15 minutes after injection and fewer neonatal complications, especially in the Apgar score.

scholarly journals Is Infusion of Subhypnotic Propofol as Effective as Dexamethasone in Prevention of Postoperative Nausea and Vomiting Related to Laparoscopic Cholecystectomy? A Randomized Controlled Trial

2015 ◽  
Vol 2015 ◽  
pp. 1-5 ◽  
Author(s):  
Mine Celik ◽  
Aysenur Dostbil ◽  
Mehmet Aksoy ◽  
Ilker Ince ◽  
Ali Ahiskalioglu ◽  
...  
Keyword(s):  
Laparoscopic Cholecystectomy ◽  
Postoperative Nausea ◽  
Controlled Trial ◽  
Postoperative Nausea And Vomiting ◽  
Nausea And Vomiting ◽  
Controlled Study ◽  
Control Group ◽  
Double Blind ◽  
Significant Difference ◽  
Group D

Background. Postoperative nausea and vomiting (PONV) is one of common complications in patients undergoing laparoscopic cholecystectomy (LC). Aim of this study was to compare the efficacy of subhypnotic (1 mg/kg/h) infusion of propofol with dexamethasone on PONV in patients undergoing LC.Methods. A total of 120 patients were included in this randomized, double-blind, placebo-controlled study. Patients were randomly assigned to 3 groups; patients of group dexamethasone (group D) were administrated 8 mg dexamethasone before induction of anesthesia, patients of group propofol (group P) were infused to subhypnotic (1 mg/kg/h) propofol during operation and patients of group control (group C) were applied infusion of 10% intralipid. The incidence of PONV and needs for rescue analgesic and antiemetic were recorded in the first 24 h postoperatively.Results. In the 0–24 h, the incidence of PONV was significantly lower in the group D and group P compared with the group C (37.5%, 40%, and 72.5%, resp.). There was no significant difference in the incidence of PONV and use of antiemetics and analgesic between group D and group P.Conclusion. We concluded that infusion of propofol 1 mg/kg/h is as effective as dexamethasone for the prevention of PONV during the first 24 hours after anesthesia in patients undergoing LC.

scholarly journals A Comparison of Analgesic Effect between Preoperative and Postoperative Transversus Abdominis Plane (TAP) Blocks for Different Durations of Laparoscopic Gynecological Surgery

2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Meiyu Wei ◽  
Ming Liu ◽  
Jie Liu ◽  
Haitao Yang
Keyword(s):  
Postoperative Pain ◽  
Pain Score ◽  
Postoperative Analgesia ◽  
Postoperative Nausea And Vomiting ◽  
Transversus Abdominis ◽  
Gynecological Surgery ◽  
Tap Block ◽  
Transversus Abdominis Plane ◽  
Postoperative Pain Score ◽  
Duration Of Surgery

Aim. This study aims to compare the postoperative analgesia between preoperative and postoperative ultrasound-guided transversus abdominis plane (TAP) blocks for different durations of laparoscopic gynecological surgery. Methods. A total of 120 patients, ASA I-III, 18–65 years of age, were divided randomly into 2 groups: preoperative TAP group (pre-TAP group) and postoperative TAP group (post-TAP group). Patients in the pre-TAP group (n = 60) and post-TAP group (n = 60) received bilateral TAP blocks of 0.375% ropivacaine, 40 mL, preoperatively and postoperatively, respectively. Duration of surgery, postoperative pain score, consumption of analgesics, and postoperative nausea and vomiting (PONV) during the first 24 h postoperatively were recorded. Results. For all the patients in the two groups, similar analgesia was obtained with no statistical difference. The same results were found in duration of surgery <180 min. Meanwhile, patients undergoing surgery >180 min in the post-TAP group obtained lower postoperative pain score, lower analgesics consumption, and higher satisfaction score than those in the pre-TAP group. Conclusion. Postoperative TAP block could offer better postoperative analgesia than preoperative TAP block for patients undergoing surgery >180 min. No difference was found in analgesia effect between preoperative TAP block and postoperative TAP block for patients undergoing surgery <180 min.

scholarly journals Comparison of Granisetron and Granisetron Plus Dexamethasone for the Prevention of Post-operative Nausea and Vomiting (PONV)

2007 ◽  
Vol 8 (Number 1) ◽  
pp. 21-27
Author(s):  
K S Islam ◽  
S M Bakhtiar ◽  
M A Mannan
Keyword(s):  
Postoperative Nausea And Vomiting ◽  
Complete Response ◽  
Nausea And Vomiting ◽  
Combination Group ◽  
Double Blind Study ◽  
Double Blind ◽  
Significant Difference ◽  
Group B ◽  
Post Operative Nausea ◽  
Induction Of Anaesthesia

77tere is a high incidence of postoperative nausea and vomiting (PONV) in patients undergoing surer, and anaesthesia. Many factors are claimed to be responsible for POW. This stad.v MU designed to compare the effectiveness of grornsetron pits desomethasone with gran isetron alone to prevent post-operative nausea and vomiting. In this randomised double blind study. sixty patients were divided into two egnal groups ( n=30 each ). Patients in Group A received granisetron 40 pion per kg before inductor of anaesthesia and those in Group B received gmnisetron 40 pp: per kg phis devamethasone 8 nog before induction of anaesthesia. All the patients were observed for post-opera tive nausea and vaniting for 24 hours (0-6 hours in the recovety room and 18 hours in ward or cabin). A significant difference was found in complete response, defined as no pos,opertalve nausea and vomiting. between patients of graniserron alone group and those of granisetron pins dexamethasone combination group. The combination of grontsoron plus de.tainethasone is considered to be more effective for prevention of post-operative nausea and vomiting.

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