scholarly journals Risk Factor Assessment in a Greek Cohort of Patients With Large Abdominal Aortic Aneurysms

Angiology ◽  
2018 ◽  
Vol 70 (1) ◽  
pp. 35-40 ◽  
Author(s):  
Georgios Makrygiannis ◽  
Evanthia Mourmoura ◽  
Konstantinos Spanos ◽  
Nikolaos Roussas ◽  
Helena Kuivaniemi ◽  
...  
Keyword(s):  
Risk Factors ◽  
Family History ◽  
Screening Program ◽  
Multiple Logistic Regression Analysis ◽  
Abdominal Aortic Aneurysms ◽  
Aortic Aneurysms ◽  
Aortic Dilatation ◽  
Nucleotide Polymorphisms ◽  
Current Smoking ◽  
Abdominal Aortic

Environmental and genetic risk factors contribute to the etiology of abdominal aortic aneurysms (AAAs). Matrix metalloproteinases (MMPs) have been associated with the pathophysiology of AAAs. A prospective, nonrandomized case–control study was undertaken to investigate the risk factors for large AAAs (≥5.5 cm) among 175 male Greek AAA patients and to compare the results with a cohort of 166 male controls free from any aortic dilatation, as confirmed by ultrasonography from an existing AAA screening program in the same region. We also assessed the potential association between 2 functional single nucleotide polymorphisms in the genes MMP9 (−1561C/T; rs3918242) and MMP13 (−77A/G; rs2252070), and the presence of large AAAs. Multiple logistic regression analysis revealed AAA family history ( P = .028), hypercholesterolemia ( P < .001), and current smoking ( P < .001) as AAA risk factors. Statistical difference was reached in genotype ( P = .047) and allele ( P = .037) frequencies for rs2252070, but the results did not remain significant after correction for multiple testing. No significant differences in genotype or allele frequencies for rs3918242 were detected. In summary, AAA family history, hypercholesterolemia, and current smoking were found to be risk factors for large AAAs.

Mortality rates and risk factors for emergent open repair of abdominal aortic aneurysms in the endovascular era

2017 ◽  
Vol 70 (1) ◽  
pp. 129-136 ◽  
Author(s):  
Felice Pecoraro ◽  
Steffen Gloekler ◽  
Caecilia E. Mader ◽  
Malgorzata Roos ◽  
Lyubov Chaykovska ◽  
...  
Keyword(s):  
Risk Factors ◽  
Open Repair ◽  
Abdominal Aortic Aneurysms ◽  
Mortality Rates ◽  
Aortic Aneurysms ◽  
Abdominal Aortic

RISK FACTORS FOR TYPE II ENDOLEAKS AFTER ENDOVASCULAR REPAIR OF ABDOMINAL AORTIC ANEURYSMS

2008 ◽  
Vol 78 (1-2) ◽  
pp. 61-63 ◽  
Author(s):  
Ranjana Warrier ◽  
Robert Miller ◽  
Rick Bond ◽  
Ian K. Robertson ◽  
Peter Hewitt ◽  
...  
Keyword(s):  
Risk Factors ◽  
Endovascular Repair ◽  
Abdominal Aortic Aneurysms ◽  
Aortic Aneurysms ◽  
Type Ii ◽  
Abdominal Aortic

The similarities and differences among patients with abdominal aortic aneurysms referred to a tertiary hospital and found at necropsy

Vascular ◽  
2014 ◽  
Vol 23 (4) ◽  
pp. 411-418 ◽  
Author(s):  
Erasmo S da Silva ◽  
Vitor C Gornati ◽  
Ivan B Casella ◽  
Ricardo Aun ◽  
Andre EV Estenssoro ◽  
...  
Keyword(s):  
Risk Factors ◽  
Abdominal Aortic Aneurysm ◽  
Aortic Aneurysm ◽  
Protective Factor ◽  
Abdominal Aortic Aneurysms ◽  
Aortic Aneurysms ◽  
Maximum Diameter ◽  
Transverse Diameter ◽  
Abdominal Aortic ◽  
Tertiary Center

Objective To analyze the characteristics of patients with abdominal aortic aneurysms referred to a tertiary center and to compare with individuals with abdominal aortic aneurysm found at necropsy. Methods We have retrospectively analyzed the medical records of 556 patients with abdominal aortic aneurysm and 102 cases abdominal aortic aneurysm found at necropsy. Results At univariated analysis, hypertension, tobacco use and maximum diameter were significant risk factors for symptomatic aneurysm, while diabetes tended to be a protective factor for rupture. By logistic regression analysis, the largest transverse diameter was the only one significantly associated with abdominal aortic aneurysm rupture ( p < .0001, odds ratio 1.7, 95% confidence interval 1.481–1.951). Intact abdominal aortic aneurysm found at necropsy showed similarities with outpatients in relation to abdominal aortic aneurysm diameter and risk factors. Conclusion Intact abdominal aortic aneurysm at necropsy and at outpatients setting showed similarities that confirmed that abdominal aortic aneurysm repair is less offered to women, and they died more frequently with intact abdominal aortic aneurysm from other causes.

Screening Program of Abdominal Aortic Aneurysm

Angiology ◽  
2019 ◽  
Vol 70 (5) ◽  
pp. 407-413 ◽  
Author(s):  
Muriel Sprynger ◽  
Michel Willems ◽  
Hendrik Van Damme ◽  
Benny Drieghe ◽  
J. C. Wautrecht ◽  
...  
Keyword(s):  
Health Care Providers ◽  
Screening Program ◽  
Abdominal Aortic Aneurysms ◽  
Aortic Aneurysms ◽  
Ultrasound Screening ◽  
Care Providers ◽  
Abdominal Ultrasonography ◽  
Screening Programs ◽  
Abdominal Aortic ◽  
Elective Repair

In Europe, the prevalence of abdominal aortic aneurysms (AAAs) in the elderly population (≥65 year old) has declined in the past decades to <4%. Aneurysmal degeneration of the aorta is a serious and potentially life-threatening vascular disease. Abdominal aortic aneurysms typically develop subclinically and often only become symptomatic when complicated by impending rupture. Most AAAs are discovered incidentally while investigating for an unrelated pathology. Ruptured AAA is the tenth leading cause of death in Belgium (0.32% of all deaths in 2014). Health-care providers have emphasized the importance of early detection of AAA and elective repair when the rupture risk outweighs operative risk (usual diameter threshold of 55 mm). Routine AAA screening programs, consisting of a single abdominal ultrasonography at the age of 65 years, aim to reduce the number of AAA-related deaths. Does population-based ultrasound screening for AAA achieve its objective and is it cost-effective? This literature review tries to answer these challenging questions.

Screening for abdominal aortic aneurysms: An analysis of the private and indirect costs in a hospital-based screening program

2011 ◽  
Vol 10 (04) ◽  
pp. 246-249
Author(s):  
Sten Vammen ◽  
Jes Lindholt ◽  
Svend Juul ◽  
Eskild Henneberg ◽  
Helge Fasting
Keyword(s):  
Screening Program ◽  
Indirect Costs ◽  
Abdominal Aortic Aneurysms ◽  
Aortic Aneurysms ◽  
Abdominal Aortic

scholarly journals Family history of aortic aneurysm is an independent risk factor for more rapid growth of small abdominal aortic aneurysms in Japan

2015 ◽  
Vol 61 (2) ◽  
pp. 287-290 ◽  
Author(s):  
Atsushi Akai ◽  
Yoshiko Watanabe ◽  
Katsuyuki Hoshina ◽  
Yukio Obitsu ◽  
Juno Deguchi ◽  
...  
Keyword(s):  
Risk Factor ◽  
Family History ◽  
Aortic Aneurysm ◽  
Rapid Growth ◽  
Independent Risk Factor ◽  
Abdominal Aortic Aneurysms ◽  
Aortic Aneurysms ◽  
Abdominal Aortic ◽  
History Of
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