scholarly journals Competitive Binding Investigations and Quantitation in Surface-Enhanced Raman Spectra of Binary Dye Mixtures

2017 ◽  
Vol 72 (1) ◽  
pp. 60-68 ◽  
Author(s):  
Mircea A. Comanescu ◽  
Cyril Muehlethaler ◽  
John R. Lombardi ◽  
Marco Leona ◽  
Thomas A. Kubic
Keyword(s):  
Spectral Characteristics ◽  
Synthesis Method ◽  
Nanoparticle Synthesis ◽  
Peak Height ◽  
Calibration Models ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Standard Calibration ◽  
One Year ◽  
Selection Of

This research presents a study in surface-enhanced Raman quantitation of dyes present in mixtures of alizarin and purpurin using standard calibration curves and Langmuir isotherm calibration models. Investigations of the nature of competitive adsorption onto silver nanoparticles by centrifugation indicates that both dyes in the mixture interact with the nanoparticles simultaneously, but only the stronger adsorbing one is seen to dominate the spectral characteristics. Calibration can be carried out by careful selection of peaks characteristic to each dye in the mixture. Comparisons of peak height and peak area calibrations reveal that peak heights, when selected by the maximum value and accounting for peak shifts, prove the better model for quantitation. It is also shown that the microwave nanoparticle synthesis method produces stable nanoparticles with a shelf-life of at least one year that give very little variation within and between uses.

Physically Self-assembled Au Nanorod Arrays for SERS

2006 ◽  
Vol 951 ◽  
Author(s):  
Motofumi Suzuki ◽  
Kaoru Nakajima ◽  
Kenji Kimura ◽  
Takao Fukuoka ◽  
Yasushige Mori
Keyword(s):  
Raman Spectroscopy ◽  
Low Cost ◽  
Major Axis ◽  
Surface Enhanced Raman Spectroscopy ◽  
Nanorod Arrays ◽  
Au Nanorods ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Oblique Deposition ◽  
Selection Of

ABSTRACTWe have demonstrated surface-enhanced Raman spectroscopy on arrays of Au nanorods aligned in line by a dynamic oblique deposition technique. For the light polarized along the major axis of the nanorods, the plasma resonance of the Au nanorods has been tuned to a wavelength suitable for Raman spectroscopy. The Raman scattering on the discrete nanorods is enhanced significantly compared with that on semi continuous Au films. Since the preparation process is physically bottom-up, it is robust in its selection of the materials and is useful in providing the SERS sensors at low cost.

scholarly journals Multibranch Gold Nanoparticles as Surface-Enhanced Raman Spectroscopy Substrates for Rapid and Sensitive Analysis of Fipronil in Eggs

Sensors ◽  
2019 ◽  
Vol 19 (24) ◽  
pp. 5354 ◽  
Author(s):  
Haonuan Zhao ◽  
Dandan Huang ◽  
Shuhua Zhu
Keyword(s):  
Gold Nanoparticles ◽  
Raman Spectroscopy ◽  
Calibration Method ◽  
Surface Enhanced Raman Spectroscopy ◽  
Oriented Growth ◽  
Low Surface Energy ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Standard Calibration ◽  
Optimized Conditions

A sensitive strategy to rapidly detect fipronil residues in eggs using multibranch gold nanoparticles (AuNPs) as the substrate of surface-enhanced Raman spectroscopy (SERS) was investigated in this study. Under optimized conditions, fipronil molecules preferentially deposited on the multibranch gold nanoparticles with preferential (111) facet-oriented growth due to its low surface energy. This anisotropic growth promoted the increase of SERS “hot spots”, inducing a huge enhancement of Raman signals of the fipronil. An external standard calibration method was employed for quantitative analysis, and the method was validated for linearity, sensitivity, repeatability and recovery. Good linearity were found in the concentration range of 10 ng/L~10 mg/L in fipronil acetone solution (R2 = 0.9916) and 8 × 10−5 mg/m2 to 0.8 mg/m2 on eggshells (R2 = 0.9906), respectively. The recovery rate based on acetone recovered fipronil on eggshells and in egg liquids was 80.13%~87.87%, and 81.34%~88.89%, respectively. The SERS assay was successfully used to monitor fipronil in eggs.

Surface-Enhanced Raman Scattering Fiber-Optic Sensor

1990 ◽  
Vol 44 (1) ◽  
pp. 63-69 ◽  
Author(s):  
J. M. Bello ◽  
T. Vo-Dinh
Keyword(s):  
Raman Scattering ◽  
Fiber Optic ◽  
Limit Of Detection ◽  
Spectral Characteristics ◽  
Surface Enhanced Raman Scattering ◽  
Fiber Optic Sensor ◽  
Optic Sensor ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering

A fiber-optic system was developed for exciting and collecting surface-enhanced Raman scattering (SERS) signals generated from a sensing plate tip having silver-coated microparticles deposited on a glass support. Various fiber parameters, such as fiber type, fiber-substrate geometry, and other experimental parameters, were investigated to obtain the optimum conditions for the SERS fiber-optic device. In addition, analytical figures of merit relevant to the performance of the SERS fiber-optic sensor, such as SERS spectral characteristics, reproducibility, linear dynamic range, and limit of detection, were also investigated.

scholarly journals Biosensing Using SERS Active Gold Nanostructures

Nanomaterials ◽  
2021 ◽  
Vol 11 (10) ◽  
pp. 2679
Author(s):  
Gour Mohan Das ◽  
Stefano Managò ◽  
Maria Mangini ◽  
Anna Chiara De De Luca
Keyword(s):  
High Sensitivity ◽  
Surface Enhanced Raman Spectroscopy ◽  
Fingerprint Recognition ◽  
Chemical Enhancement ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Sensor Configuration ◽  
Relevant Factors ◽  
Selection Of

Surface-enhanced Raman spectroscopy (SERS) has become a powerful tool for biosensing applications owing to its fingerprint recognition, high sensitivity, multiplex detection, and biocompatibility. This review provides an overview of the most significant aspects of SERS for biomedical and biosensing applications. We first introduced the mechanisms at the basis of the SERS amplifications: electromagnetic and chemical enhancement. We then illustrated several types of substrates and fabrication methods, with a focus on gold-based nanostructures. We further analyzed the relevant factors for the characterization of the SERS sensor performances, including sensitivity, reproducibility, stability, sensor configuration (direct or indirect), and nanotoxicity. Finally, a representative selection of applications in the biomedical field is provided.

Surface enhanced Raman scattering of dendritic Ag nanostructures grown with anodic aluminium oxide

RSC Advances ◽  
2016 ◽  
Vol 6 (40) ◽  
pp. 33348-33352 ◽  
Author(s):  
L. D. Rafailović ◽  
C. Gammer ◽  
J. Srajer ◽  
T. Trišović ◽  
J. Rahel ◽  
...  
Keyword(s):  
Raman Scattering ◽  
Aluminium Oxide ◽  
Surface Enhanced Raman Scattering ◽  
Long Term Stability ◽  
Anodic Aluminium Oxide ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering ◽  
One Year

Ag dendrites grown simultaneously with anodic aluminium oxide showing long-term stability for reuse even after one year and a simulated Ag dendrite both demonstrating surface enhanced Raman scattering.

Quantification of Protein Biomarker Using SERS Nano-Stress Sensing with Peak Intensity Ratiometry

2016 ◽  
Vol 04 (03) ◽  
pp. 1640011 ◽  
Author(s):  
Douglas Goh ◽  
Kien Voon Kong ◽  
Perumal Jayakumar ◽  
Tianxun Gong ◽  
U.S. Dinish ◽  
...  
Keyword(s):  
Low Cost ◽  
Spectral Characteristics ◽  
Surface Enhanced Raman Spectroscopy ◽  
Biological Molecules ◽  
Peak Intensity Ratio ◽  
Peak Intensity ◽  
Sensing Platform ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Stress Sensing

We report a surface enhanced Raman spectroscopy (SERS) ratiometry method based on peak intensity coupled in a nano-stress sensing platform to detect and quantify biological molecules. Herein, we employed an antibody-conjugated [Formula: see text]-aminothiophenol (ATP) functionalized on a bimetallic-film-over-nanosphere (BMFON) substrate as a sensitive SERS platform to detect human haptoglobin (Hp) protein, which is an acute phase protein and a biomarker for various cancers. Correlation between change in the ATP spectral characteristics and concentration of Hp protein was established by examining the peak intensity ratio at 1572[Formula: see text]cm[Formula: see text] and 1592[Formula: see text]cm[Formula: see text] that reflects the degree of stress experienced by the aromatic ring of ATP during Hp protein–antibody interaction. Development of this platform shows the potential in developing a low-cost and sensitive SERS sensor for the pre-screening of various biomarkers.

Multi-branched gold nanoparticles for Surface Enhanced Raman scattering characterization

2014 ◽  
Vol 1625 ◽  
Author(s):  
Jencilin Johnston ◽  
Erik N. Taylor ◽  
Richard J. Gilbert ◽  
Thomas J. Webster
Keyword(s):  
Gold Nanoparticles ◽  
Raman Scattering ◽  
Noble Metals ◽  
Fluorescent Dyes ◽  
Synthesis Method ◽  
Surface Enhanced Raman Scattering ◽  
Raman Signal ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering

ABSTRACTSurface enhanced Raman scattering (SERS) is a sensitive and reproducible vibrational spectroscopic technique used to detect and characterize molecules near the surface of noble metals like Au, Ag, Pt, Cu, etc. SERS enhances Raman signals through light-induced plasmonic vibrations occurring on irregular metal surfaces and localized electromagnetic augmentation. To better define nano-scale regions of the Raman signal enhancement, we generated gold nanoparticles with a unique multi-branched configuration along with surface-adsorbed fluorescent reporter molecules. The reporter molecules included a set of near-infra red active fluorescent dyes IR820 (green cyanine, photo electronic dye), DTTC (3, 3'-diethylthiatricarbocyanine iodide) and DTDC (3, 3'- diethylthiadicarbocyanine iodide). We employed a one-pot synthesis method in order to generate a stellate configuration in gold nanoparticles through the reduction of HAuCl4 with Good’s buffer, HEPES, at pH 7.4 and room temperature. A cell viability assay was performed with normal esophageal cells exposed to the multi-branched gold nanoparticles and SERS molecules to assess their toxicity. Our results demonstrate the capacity of multibranched gold nanoparticles linked to Raman reporter molecules to generate distinct signature spectra and, with the exception of the gold nanoparticles functionalized with DTTC, remain non-toxic to normal esophageal cells.

scholarly journals Surface enhanced Raman spectroscopy platform based on graphene with one-year stability

2016 ◽  
Vol 604 ◽  
pp. 74-80 ◽  
Author(s):  
Teddy Tite ◽  
Vincent Barnier ◽  
Christophe Donnet ◽  
Anne–Sophie Loir ◽  
Stéphanie Reynaud ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Surface Enhanced Raman Spectroscopy ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
One Year

scholarly journals Quantitative surface-enhanced Raman spectroscopy for kinetic analysis of aldol condensation using Ag–Au core–shell nanocubes

The Analyst ◽  
2016 ◽  
Vol 141 (21) ◽  
pp. 6051-6060 ◽  
Author(s):  
Joshua D. Weatherston ◽  
Nolan C. Worstell ◽  
Hung-Jen Wu
Keyword(s):  
Kinetic Analysis ◽  
Aldol Condensation ◽  
Condensation Reaction ◽  
Internal Standard ◽  
Surface Enhanced Raman Spectroscopy ◽  
Core Shell ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Standard Calibration ◽  
Enhanced Raman Scattering

Ag–Au core–shell nanocube-based surface-enhanced Raman scattering (SERS) probes utilizing internal standard calibration for quantitative kinetic analysis of the aldol condensation reaction.

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