Is There Benefit in Identifying Asthma Triggers During an Exacerbation?

Introduction. Allergen-specific IgE (sIgE) testing provides an objective assessment of sensitization to an allergen. Goal. To identify the time when serum measurements of sIgE would be most sensitive. Methods. This was a prospective study conducted between September 1, 2015, and February 25, 2019. Subjects ≥5 and ≤18 years of age, seen in the ED or admitted with an asthma exacerbation, were tested for total IgE and 8 perennial sIgE levels. Subjects with elevated sIgE were tested again after symptom resolution. Results. A total of 104 subjects were enrolled; 50 subjects were eligible for inclusion in the analysis. There were statistically significant differences between the visits for all sIgE, except Alternaria alternatum. Conclusions. In pediatric patients, serum sIgE levels measured during an asthma exacerbation were elevated compared with when their asthma was in better control. sIgE testing during an asthma exacerbation may help identify asthma triggers, mitigate exposure, and hence improve asthma control.

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Total IgE, Specific IgE and Prick-Tests Against Foods in Common Migraine—A Prospective Study

Cephalalgia ◽

10.1046/j.1468-2982.1983.0304231.x ◽

1983 ◽

Vol 3 (4) ◽

pp. 231-234 ◽

Cited By ~ 21

Author(s):

A. Pradalier ◽

S. Weinman ◽

J. M. Launay ◽

J. F. Baron ◽

J. Dry

Keyword(s):

Prospective Study ◽

Low Frequency ◽

Food Challenge ◽

Specific Ige ◽

Food Allergens ◽

Total Ige ◽

Very Low Frequency ◽

Common Food ◽

Class 1 ◽

A Prospective Study

A prospective study of total IgE, specific IgE against 12 common foods, and prick-tests with 11 common food allergens was performed on 50 consecutive migraine sufferers. Total IgE levels were found above 100 kU/I for seven patients, but five of them were atopic. Prick-tests and PAST were positive for four and six patients (class 1), respectively. Food challenge on these six patients did not cause any migraine attacks. This study thus indicates a very low frequency of allergic dietary migraine to common foods.

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A prospective study of 17 consecutive pediatric patients with chronic non-bacterial osteomyelitis treated with intravenous pamidronate over a 15 year period at a single center reveals excellent clinical and radiologic outcome initially and after flare

Bone Abstracts ◽

10.1530/boneabs.7.p132 ◽

2019 ◽

Author(s):

Paivi Miettunen ◽

Chloe Stephenson ◽

Seamus Stephenson ◽

Xing-Chang Wei

Keyword(s):

Prospective Study ◽

Pediatric Patients ◽

Single Center ◽

Intravenous Pamidronate ◽

A Prospective Study

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Longitudinal Trajectory of Fatigue in Patients With Inflammatory Bowel Disease: A Prospective Study

Inflammatory Bowel Diseases ◽

10.1093/ibd/izaa338 ◽

2020 ◽

Author(s):

Nienke Z Borren ◽

Millie D Long ◽

Robert S Sandler ◽

Ashwin N Ananthakrishnan

Keyword(s):

Ulcerative Colitis ◽

Inflammatory Bowel Disease ◽

Chronic Illness ◽

Prospective Study ◽

Functional Assessment ◽

Bowel Disease ◽

Symptom Resolution ◽

Chronic Illness Therapy ◽

Inflammatory Bowel ◽

A Prospective Study

Abstract Background Fatigue is a disabling symptom in patients with inflammatory bowel disease (IBD). Its prevalence, mechanism, and impact remain poorly understood. We determined changes in fatigue status over time and identified predictors of incident or resolving fatigue. Methods This was a prospective study nested within the IBD Partners cohort. Participants prospectively completed the Multidimensional Fatigue Inventory and the Functional Assessment of Chronic Illness Therapy-Fatigue at baseline, 6 months, and 12 months. A Functional Assessment of Chronic Illness Therapy-Fatigue score ≤43 defined significant fatigue. Multivariable regression models using baseline covariates were used to identify risk factors for incident fatigue at 6 months and to predict the resolution of fatigue. Results A total of 2429 patients (1605 with Crohn disease, 824 with ulcerative colitis) completed a baseline assessment, and 1057 completed a second assessment at 6 months. Persistent fatigue (at baseline and at 6 months) was the most common pattern, affecting two-thirds (65.8%) of patients. One-sixth (15.7%) of patients had fatigue at 1 timepoint, whereas fewer than one-fifth (18.5%) of patients never reported fatigue. Among patients not fatigued at baseline, 26% developed fatigue at 6 months. The strongest predictor of incident fatigue was sleep disturbance at baseline (odds ratio, 2.91; 95% confidence interval, 1.48–5.72). In contrast, only 12.3% of those with fatigue at baseline had symptom resolution by month 6. Resolution was more likely in patients with a diagnosis of ulcerative colitis, quiescent disease, and an absence of significant psychological comorbidity. Conclusions Fatigue is common in patients with IBD. However, only a few fatigued patients experience symptom resolution at 6 or 12 months, suggesting the need for novel interventions to ameliorate its impact.

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947 A prospective study of adherence with peak expiratory flow rate monitoring in pediatric patients using a portable electronic monitoring device versus a standard peak flow meter

Journal of Allergy and Clinical Immunology ◽

10.1016/s0091-6749(00)91375-7 ◽

2000 ◽

Vol 105 (1) ◽

pp. S322

Author(s):

J STAHLMAN

Keyword(s):

Prospective Study ◽

Peak Expiratory Flow ◽

Flow Rate ◽

Peak Expiratory Flow Rate ◽

Pediatric Patients ◽

Electronic Monitoring ◽

Peak Flow ◽

Monitoring Device ◽

Electronic Monitoring Device ◽

A Prospective Study

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Objectivity in subjectivity: do students’ self and peer assessments correlate with examiners’ subjective and objective assessment in clinical skills? A prospective study

BMJ Open ◽

10.1136/bmjopen-2016-012289 ◽

2017 ◽

Vol 7 (5) ◽

pp. e012289 ◽

Cited By ~ 5

Author(s):

A'man Talal Inayah ◽

Lucman A Anwer ◽

Mohammad Abrar Shareef ◽

Akram Nurhussen ◽

Haifa Mazen Alkabbani ◽

...

Keyword(s):

Prospective Study ◽

Clinical Skills ◽

Objective Assessment ◽

A Prospective Study

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Radiofrequency ablation turbinoplasty improves the sense of smell in pediatric patients: A prospective study

International Journal of Pediatric Otorhinolaryngology ◽

10.1016/j.ijporl.2021.110935 ◽

2021 ◽

pp. 110935

Author(s):

Christian Calvo-Henriquez ◽

Franklin Mariño-Sánchez ◽

Jerome R. Lechien ◽

Byron Maldonado Alvarado ◽

Antonino Maniaci ◽

...

Keyword(s):

Radiofrequency Ablation ◽

Prospective Study ◽

Pediatric Patients ◽

Sense Of Smell ◽

A Prospective Study

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Value of Preoperative Chest X-ray Examinations in Children

PEDIATRICS ◽

10.1542/peds.60.5.669 ◽

1977 ◽

Vol 60 (5) ◽

pp. 669-672

Author(s):

Shashikant M. Sane ◽

Robert A. Worsing ◽

Cornelius W. Wiens ◽

Rajiv K. Sharma

Keyword(s):

Prospective Study ◽

Pediatric Patients ◽

Anesthetic Technique ◽

Chest Film ◽

X Ray ◽

Patients Âgés ◽

Chest X Ray ◽

A Prospective Study ◽

Preoperative Chest

To assess the value of routine preoperative chest x-ray films in pediatric patients, a prospective study of 1,500 patients, ages newborn to 19 years, was undertaken. Of all the patients, 7.5% demonstrated at least one roentgenographic abnormality, with 4.7% of the patients demonstrating a totally unsuspected significant roentgenographic anomaly. In 3.8% of the patients, surgery was either postponed or cancelled or the anesthetic technique was altered as a result of the roentgenographic finding. It is believed that the routine preoperative chest film is justified if the film is evaluated before surgery and the results clinically followed up.

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