The Influence of Binocular Vision Symptoms on Computerized Neurocognitive Testing of Adolescents With Concussion

2020 ◽  
Vol 59 (11) ◽  
pp. 961-969
Author(s):  
Adam J. Peiffer ◽  
James MacDonald ◽  
Drew Duerson ◽  
Gladys Mitchell ◽  
Andrew T. E. Hartwick ◽  
...  
Keyword(s):  
Binocular Vision ◽  
Test Performance ◽  
Predictive Accuracy ◽  
Symptom Burden ◽  
Control Group ◽  
Vision Disorders ◽  
Vision Disorder ◽  
Convergence Insufficiency ◽  
Neurocognitive Test ◽  
The Relationship

Binocular vision disorders are commonly found postconcussion and associated with high symptom burden. We investigated the relationship between binocular vision symptoms and neurocognitive test performance. Thirty-four adolescents with concussion and 18 without concussion were assessed for cognitive performance using the CogState Brief Battery. Binocular vision disorders were determined using clinical examination and vision symptoms with the Convergence Insufficiency Symptoms Survey (CISS). A cutoff CISS score of 13 had high predictive accuracy for identifying individuals with a binocular vision disorder. CogState scores for processing speed and attention were significantly lower in the concussion group compared with the control group. Within the concussion group, scores for attention, learning, and working memory were significantly lower in those with vision symptoms. The presence of vision symptoms did not significantly affect CogState scores within the control group. The presence of vision symptoms in individuals with concussion is associated with significantly reduced scores on individual components of the CogState.

Parkinson's disease and convergence insufficiency: a mini-review

2021 ◽  
Vol 1 (3) ◽  
pp. 108-111
Author(s):  
Mashael Al-Namaeh
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Clinical Trials ◽  
Control Group ◽  
Healthy Controls ◽  
Inclusion Criteria ◽  
Medline Search ◽  
Convergence Insufficiency ◽  
Eye Examination ◽  
The Relationship

Background: A key manifestation of Parkinson’s disease (PD) is visual impairment. Cognitive impairment has been found to overlap with convergence insufficiency (CI) in patients with PD and is associated with significantly greater near point convergence (NPC) distance. Difficulty in reading and diplopia were the most common symptoms of CI in PD. The prevalence of CI is greater among patients with PD. Therefore, this study aimed to assess the relationship between PD and CI. Methods: Studies that had included data on CI, NPC, or both were selected by searching PubMed/MEDLINE and clinicaltrails.gov, without any timeline or language limitation. The following terms were used in PubMed/MEDLINE search: ‘Clinical Trials’, ‘Parkinson’s Disease’, and ‘Convergence Insufficiency’. For clinical trials.gov database, the terms ‘Parkinson’s Disease’, ‘Convergence Insufficiency’, and ‘Completed Studies’ were used. Only those studies with control subjects were included. PubMed/MEDLINE search yielded 1,563 articles, but no article was found in the clinical trails.gov search. Twelve articles met the inclusion criteria, among which nine articles were selected as they had data on CI or NPC distance (cm), and PD.   Results: Overall, there were 1,563 articles; among them, 12 articles met the inclusion criteria. Nine articles were selected based on their data concerning CI or NPC distance (cm) and PD. Relative to the control group, the PD group had high CI. In addition, PD group showed increase in NPC distance than the control group. Conclusions: These data suggest that the patients with PD had an increased likelihood of developing CI visual symptoms, and increased NPC distance than healthy controls. These findings indicate that regular eye examination is very important for patients with PD.

Cognitive Structure Variables in Prose Learning

1976 ◽  
Vol 8 (1) ◽  
pp. 47-66 ◽  
Author(s):  
Joseph R. Jenkins ◽  
R. Barker Bausell
Keyword(s):  
Test Performance ◽  
Group Performance ◽  
Cognitive Structure ◽  
Learning Control ◽  
Control Group ◽  
Facilitative Effect ◽  
Type Test ◽  
Prose Learning ◽  
Key Terms ◽  
The Relationship

Four experiments were performed to determine the relationship between knowledge of meanings for key terms and the acquisition of information from prose. In Experiment I knowledge of meanings significantly influenced prose learning. Control group performance indicated that meaning knowledge did not independently influence test performance. In Experiment II with different materials the same factor, knowledge of meaning, did not facilitate learning from prose as measured by a verbatim-type test. A conceptual measure, however, revealed a facilitative effect attributed to meaning knowledge. Differences in the results of the two experiments are discussed. Experiments III and IV were designed to investigate the discrepancies from the first experiments. Neither the number of unfamiliar key terms nor the ratio of terms to prose, but the ratio of terms to related discussion was a factor which interacted with knowledge of meanings in its effect on learning from prose.

scholarly journals Clinical Characteristics of Patients Presenting with Headache at Binocular Vision Clinic: A Hospital Based Study

2020 ◽  
Vol 36 (3) ◽  
Author(s):  
Saif Hassan Alrasheed
Keyword(s):  
Binocular Vision ◽  
Clinical Characteristics ◽  
Fixation Disparity ◽  
Cross Sectional ◽  
Convergence Insufficiency ◽  
Significance Levels ◽  
Chi Squared ◽  
History Of ◽  
Maddox Rod ◽  
The Relationship

Purpose: To assess the clinical characteristics of patients presenting with headache at binocular vision clinic.Place and Duration of Study: Al-Neelain eye hospital, Sudan, from February to October 2018.Study Design: Cross-sectional study.Material and Methods: One hundred fifty patients with history of headache were included in study. Dissociated heterophoria was measured using Maddox Wing and Maddox Rod. Associated heterophoria was assessed by the Mallett unit fixation disparity and fusional vergence was measured using a prism bar. The relationship between measures was determined using the chi-squared analysis. For all statistical determinations, significance levels were set at p < 0.05.Results: Mean age was 25 ± 3.5 years. Femalesconstituted 78% and headache was significantly associated with females (P < 0.0001). Majority of patients (82%)presented with exophoria (mean = 4.74 ± 0.75 Δ Base-In) at near fixation, 10.7% were orthophoric and7.34percentage were esophoric (mean = 3.24 ± 0.5 Δ Base-Out). The association between near heterophoria andheadache was statically significant (χ2 = 7.426; p = 0.001). Association between distance heterophoria andheadache was not statistically significant (χ2 = 22.172; p = 0.265). The association between headache andpositive fusional vergence at near fixation was statically significant (p = 0.03). Leading cause of headache wasconvergence weakness exophoria (39.3%; p = 0.001), followed by convergence insufficiency (24%; p = 0.02).Conclusion: Headache was more common in females and was associated with exophoria, convergenceinsufficiency and inadequate positive fusional vergence at near fixation

scholarly journals Convergence Insufficiency - Perception Error: A Review Article

2020 ◽  
Vol 4 (2) ◽  
Keyword(s):  
Binocular Vision ◽  
Reading Performance ◽  
Vision Disorders ◽  
Eye Care ◽  
Visual Discomfort ◽  
Convergence Insufficiency ◽  
Single Vision ◽  
Vision Assessment ◽  
Proper Diagnosis ◽  
Binocular Single Vision

Ocular asthenopia associated with headaches and visual discomfort are the major complaints, clients have these days. Intensive near and digital works have brought many non-strabismic binocular vision disorders (NSBVD) in the clients. Convergence insufficiency (CI) is one of the most prevalent NSBVD. CI is a binocular vision dysfunction, characterized by the patient’s inability to accurately converge, or sustain accurate convergence when focusing on near objects. Apart from visual symptoms, CI is known to have effects on a children’s academics and a person’s daily life. In addition to visual discomfort, children with CI report symptoms affecting reading performance, such as loss of pace, loss of concentration, reading slowly, and trouble remembering what was read. Proper diagnosis of convergence insufficiency is simple, but it has been complicated by the unavailability of essential orthoptic tools; the attitude of practitioner and their knowledge adds to the hurdle. Why don’t we introduce term “CI Suspect” like “Glaucoma-Suspect” so that every individual if matches one or more criteria for CI diagnosis is subjected undergo a complete binocular single vision assessment? This will properly diagnose and manage the case and also make orthoptics as a proper sub-specialty for eye care practitioners.

Adolescents’ self-mutilation - Relationship with dependent behaviour

2003 ◽  
Vol 62 (4) ◽  
pp. 241-249 ◽  
Author(s):  
M. Bolognini ◽  
B. Plancherel ◽  
J. Laget ◽  
P. Stéphan ◽  
O. Halfon
Keyword(s):  
Suicide Attempts ◽  
Clinical Sample ◽  
Control Sample ◽  
Clinical Population ◽  
Control Group ◽  
Clinical Group ◽  
Self Mutilation ◽  
Self Harm ◽  
Partial Overlap ◽  
The Relationship

The aim of this study, which was carried out in the French-speacking part of Switzerland, was to examine the relationship between suicide attempts and self-mutilation by adolescents and young adults. The population, aged 14-25 years (N = 308), included a clinical sample of dependent subjects (drug abuse and eating disorders) compared to a control sample. On the basis of the Mini Neuropsychiatric Interview ( Sheehan et al., 1998 ), DSM-IV criteria were used for the inclusion of the clinical population. The results concerning the occurrence of suicide attempts as well as on self-mutilation confirm most of the hypotheses postulated: suicidal attempts and self-mutilation were more common in the clinical group compared to the control group, and there was a correlation between suicide attempts and self-mutilation. However, there was only a partial overlap, attesting that suicide and self-harm might correspond to two different types of behaviour.

Impact of Physical Activity on the Incidence of Vascular Diseases in Adults with Type 2 Diabetes Mellitus

2019 ◽  
Vol 8 ◽  
pp. 1549
Author(s):  
Babak Pezeshki ◽  
Ehsan Bahramali ◽  
Amir Ansari ◽  
Aliasghar Karimi ◽  
Mojtaba Frajam ◽  
...  
Keyword(s):  
Physical Activity ◽  
Diabetes Mellitus ◽  
Vascular Function ◽  
Vascular Diseases ◽  
Major Complication ◽  
Control Group ◽  
Case Group ◽  
Vascular Events ◽  
The Relationship

Background: Diabetes mellitus (DM) is a common metabolic disease worldwide and has many complications. The vascular events are the major complication of DM that have an important effect on mortality and disability. The physical activity (PA) enhances the vascular function by several pathways. The aim of this study was to evaluation of the relationship between PA and vascular diseases in patients with DM.Materials and Methods: This research was performed as the case-control study that was extracted from a prospective epidemiological research study in Iran (PERSIAN). The patients with type 2 DM more than six months defined as case group and the non-DM subjects in control group with ratio 1:2, and both groups were matched in the term of age and sex. The MET score was used to evaluate the level of PA and blood glucose, lipid profile, body mass index, overweight, dyslipidemia, glomerular filtration rate, myocardial infarction (MI), unstable angina, and stroke.Results: Overall, 1242 patients with DM were extracted, and 2484 non-diabetic subjects were investigated. In the case group, 355(28.6 %) and 887(71.4%) were men and women, respectively, the and 710 (28.6%) men and 1774(71.4%) women in control group. The mean MET score was 30 and 40.97 in the DM and non-DM groups, respectively (P˂0.001). The frequency of MI, stroke, and cardiac ischemia were 44 (3.5%), 37 (3%), and 267 (21.5%), respectively in DM group, and 54 (2.2%), 43 (1.7%), and 389 (15.7%), respectively in non-DM group.Conclusion: The incidence of vascular events associated with PA level in patients with DM and adherence to regular PA reduce the vascular events and DM complications. [GMJ.2019;inpress:e1549]

Impact of markers of endothelial injury and hypercoagulability on systemic lupus erythematosus

Lupus ◽  
2020 ◽  
Vol 29 (2) ◽  
pp. 182-190
Author(s):  
W Batista Cicarini ◽  
R C Figueiredo Duarte ◽  
K Silvestre Ferreira ◽  
C de Mello Gomes Loures ◽  
R Vargas Consoli ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Disease Activity ◽  
Lupus Erythematosus ◽  
Activity Index ◽  
Disease Activity Index ◽  
Endothelial Injury ◽  
Control Group ◽  
Systemic Lupus ◽  
Low Concentrations ◽  
The Relationship

We have explored the relationship between possible hemostatic changes and clinical manifestation of the systemic lupus erythematosus (SLE) as a function of greater or lesser disease activity according to Systemic Lupus Erythematosus Disease Activity Index-2000 (SLEDAI-2K) criteria. Endothelial injury and hypercoagulability were investigated in patients with SLE by measuring thrombomodulin (TM), D-dimer (DDi) and thrombin generation (TG) potential. A total of 90 participants were distributed into three groups: 1) women with SLE presenting with low disease activity (laSLE) (SLEDAI-2K ≤ 4), 2) women with SLE presenting with moderate to high disease activity (mhaSLE) (SLEDAI-2K > 4), and 3) a control group comprising healthy women. Levels of TM and DDi were higher both in the laSLE and mhaSLE groups compared to controls and in mhaSLE compared to the laSLE group. With respect to TG assay, lagtime and endogen thrombin potential, low concentrations of tissue factor provided the best results for discrimination among groups. Analysis of these data allow us to conclude that TM, DDi and TG are potentially useful markers for discriminating patients with very active from those with lower active disease. Higher SLE activity may cause endothelial injury, resulting in higher TG and consequently a hypercoagulability state underlying the picture of thrombosis common in this inflammatory disease.

scholarly journals Urinary bisphenol A in women with polycystic ovary syndrome – a possible suppressive effect on steroidogenesis?

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Zora Lazúrová ◽  
Jana Figurová ◽  
Beáta Hubková ◽  
Jana Mašlanková ◽  
Ivica Lazúrová
Keyword(s):  
Polycystic Ovary Syndrome ◽  
Bisphenol A ◽  
Steroid Hormones ◽  
Polycystic Ovary ◽  
Suppressive Effect ◽  
Human Reproduction ◽  
Control Group ◽  
Ovary Syndrome ◽  
Ovarian Steroidogenesis ◽  
The Relationship

Abstract Objectives There is a growing evidence indicating an impact of endocrine distrupting chemicals such as bisphenol A (BPA) on human reproduction. Its higher levels in serum or urine have been documented in women with polycystic ovary syndrome (PCOS), however the relationship to ovarian steroidogenesis remains unclear. Aim of the study was to compare urinary BPA (U-BPA) concentrations among PCOS women and control group. Second aim was to assess the relationship of U-BPA to ovarian steroidogenesis in the group with PCOS. Methods Eighty six Caucasian women (age 28.5 ± 5.1 years) diagnosed with PCOS and 32 controls of age 24.9 ± 4.4 years were included in the study. Fasting blood samples were analyzed for biochemical parameters and steroid hormones. U-BPA was measured in the morning urine sample using high pressure liquid chromatography. Results PCOS women had significantly higher U-BPA as compared with control group (p=0.0001). Those with high levels of U-BPA (U-BPA ≥2.14 ug/g creatinine) demonstrated higher serum insulin (p=0.029) and HOMA IR (p=0.037), lower serum estrone (p=0.05), estradiol (p=0.0126), FSH (p=0.0056), and FAI (p=0.0088), as compared with low-BPA group (U- BPA <2.14 ug/g creatinine). In PCOS women, U-BPA positively correlated with age (p=0.0026; R2=0.17), negatively with estradiol (p=0.0001, R2=0.5), testosterone (p=0.0078, R2=0.15), free-testosterone (p=0.0094, R2=0.12) and FAI (p=0.0003, R2=0.32), respectively. Conclusions PCOS women have significantly higher U-BPA concentrations than healthy controls. U-BPA positively correlates with age and negatively with ovarian steroid hormones suggesting a possible suppressive effect of bisphenol A on ovarian steroidogenesis.

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