Methadone Treatment: The Nordic Attitude

1980 ◽  
Vol 10 (4) ◽  
pp. 463-475 ◽  
Author(s):  
Olafur Hallgrimsson
Keyword(s):  
Methadone Maintenance Treatment ◽  
Maintenance Treatment ◽  
Methadone Maintenance ◽  
Methadone Treatment ◽  
Nordic Countries ◽  
Health Policies ◽  
Drug Addicts ◽  
Limited Extent

After a rapid glimpse of the American and English situations, an overview is given of Nordic health policies and attitudes regarding methadone maintenance treatment. The extent to which the method has been put into practice and finally the research done in this field is described. Scepticism about methadone maintenance is strong and only to a limited extent has it been used in the Nordic Countries. Research carried out in the Nordic countries does not clarify the international dilemma that scientific proof for the legitimacy of using a potent narcotic in the treatment of drug addicts is still absent 15 years after its development.

Association study of genetic polymorphisms in GABRD with treatment response and dose in methadone maintenance treatment

2021 ◽  
Author(s):  
Xiaohu Xie ◽  
Jun Gu ◽  
Dingding Zhuang ◽  
Xiaoyu Chen ◽  
Yun Zhou ◽  
...  
Keyword(s):  
Treatment Response ◽  
Methadone Maintenance Treatment ◽  
Maintenance Treatment ◽  
Methadone Maintenance ◽  
Methadone Treatment ◽  
Heroin Addiction ◽  
High Dose ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Delta Subunit

Aim: This study determined if gene variants in the GABA receptor delta subunit ( GABRD) are associated with treatment response and dose in methadone maintenance treatment (MMT) for heroin addiction. Materials & methods: A total of 286 MMT patients were recruited and divided into response and nonresponse groups based on retention time in therapy. A total of 177 responders were classified into low dose and high dose subgroups according to the stabilized methadone dose. Four (single nucleotide polymorphisms) SNPs (rs13303344, rs4481796, rs2376805 and rs2229110) in GABRD were genotyped using the TaqMan SNP assay. Logistic regression was used to assess the genetic effects of the SNPs in MMT. Results: No significant associations were observed between the SNPs and treatment response or dose, except the frequency of haplotype ACGC at the four SNPs significantly differed between responders and nonresponders. Conclusion: The results indicated that GABRD variants may play a small role in modulating methadone treatment response.

Development of a Brief Treatment Instrument for Routine Clinical Use with Methadone Maintenance Treatment Clients: The Methadone Treatment Index

2008 ◽  
Vol 43 (11) ◽  
pp. 1666-1680
Author(s):  
Daryle E. Deering ◽  
J. Douglas Sellman ◽  
Simon J. Adamson ◽  
Jacqueline Horn ◽  
Christopher M. A. Frampton
Keyword(s):  
Methadone Maintenance Treatment ◽  
Maintenance Treatment ◽  
Methadone Maintenance ◽  
Methadone Treatment ◽  
Clinical Use ◽  
Brief Treatment

Predictors of Treatment Retention in Enhanced and Standard Methadone Maintenance Treatment for HIV Risk Reduction

1997 ◽  
Vol 27 (2) ◽  
pp. 203-224 ◽  
Author(s):  
Christine E. Grella ◽  
Stuart E. Wugalter ◽  
M. Douglas Anglin
Keyword(s):  
Hiv Risk ◽  
Methadone Maintenance Treatment ◽  
Maintenance Treatment ◽  
Methadone Maintenance ◽  
Methadone Treatment ◽  
Early Discharge ◽  
The Public ◽  
Methadone Maintenance Treatment Program ◽  
First 90 Days ◽  
Hiv Seropositive

Survival analysis was used to determine the predictors of discharge from a methadone maintenance treatment program for heroin addicts at high-risk for HIV infection and/or transmission. A consistent set of predictors was identified that was associated with treatment discharge at 90 days, 12 months, 18 months, and 24 months. Individuals who, at intake, were HIV seropositive, were younger, used cocaine, drank alcohol daily, and scored high on measures of depression and interpersonal problems were at a higher risk for discharge. Receipt of enhanced methadone treatment, which included case management services, group participation, psychiatric services, contingency-based reinforcers, and transportation assistance, was associated with a higher probability of retention, particularly in the first 90 days. These findings can be used to target individuals who are vulnerable to early discharge from treatment and to provide adjunctive services that may improve retention. Several of these predictors, particularly cocaine use and psychological problems, have also been associated with HIV risk among methadone clients. Increasing retention in methadone treatment will not only improve treatment efficacy but will also address the public health imperative to limit the transmission of HIV.

Mydriatic Response to Topical Naloxone in Opiate Abusers

1986 ◽  
Vol 148 (1) ◽  
pp. 44-46 ◽  
Author(s):  
A. H. Ghodse ◽  
T. H. Bewley ◽  
M. K. Kearney ◽  
S. E. Smith
Keyword(s):  
Methadone Maintenance Treatment ◽  
Maintenance Treatment ◽  
Methadone Maintenance ◽  
Physical Dependence ◽  
Methadone Treatment ◽  
Acute Withdrawal ◽  
Naloxone Hydrochloride ◽  
Opiate Addicts ◽  
Peripheral Action ◽  
Withdrawal Effects

Naloxone hydrochloride eyedrops 1 mg/ml dilated the pupils of 36 out of 47 opiate addicts on methadone maintenance treatment, without precipitation of acute withdrawal effects, but not those of healthy unmedicated subjects. The response in addicts was attenuated by certain ancillary treatments and by withdrawal of methadone treatment. The size of the response suggests some potential clinical use for topical naloxone as a diagnostic test of current opioid influence and possibility of physical dependence. The local mydriatic response, which was restricted to the treated eye, indicates that the effect of opiates on the pupil in man is determined, at least in part, by a peripheral action.

scholarly journals Take-Home Dosing Experiences among Persons Receiving Methadone Maintenance Treatment During COVID-19

2020 ◽  
Author(s):  
Mary C. Figgatt ◽  
Zach Salazar ◽  
Elizabeth Day ◽  
Louise Vincent ◽  
Nabarun Dasgupta
Keyword(s):  
Methadone Maintenance Treatment ◽  
Maintenance Treatment ◽  
Treatment Guidelines ◽  
Methadone Maintenance ◽  
Methadone Treatment ◽  
List Type ◽  
Opioid Use ◽  
Opioid Treatment ◽  
Life Saving ◽  
Treatment Facilities

AbstractPurposeMethadone maintenance treatment is a life-saving treatment for people with opioid use disorders (OUD). The coronavirus pandemic (COVID-19) introduces many concerns surrounding access to opioid treatment. In March 2020, the Substance Abuse and Mental Health Services Administration (SAMHSA) issued guidance allowing the expansion of take-home methadone doses. We sought to describe changes to treatment experiences from the perspective of persons receiving methadone at outpatient treatment facilities for OUD.MethodsWe conducted an in-person survey among 104 persons receiving methadone from three clinics in central North Carolina in June and July 2020. Surveys collected information on demographic characteristics, methadone treatment history, and experiences with take-home methadone doses in the context of COVID-19 (i.e., before and since March 2020).ResultsBefore COVID-19, the clinic-level percent of participants receiving any amount of days’ supply of take-home doses at each clinic ranged from 56% to 82%, while it ranged from 78% to 100% since COVID-19. The clinic-level percent of participants receiving a take-homes days’ supply of a week or longer (i.e., ≥6 days) since COVID-19 ranged from 11% to 56%. Among 87 participants who received take-homes since COVID-19, only four reported selling their take-home doses.ConclusionsOur study found variation in experiences of take-home dosing by clinic and little diversion of take-home doses. While SAMSHA guidance should allow expanded access to take-home doses, adoption of these guidelines may vary at the clinic level. The adoption of these policies should be explored further, particularly in the context of benefits to patients seeking OUD treatment.HighlightsMethadone take-home dosing of survey participants varied by clinic.Diversion of take-home doses was rare.Implementation of COVID-19 opioid treatment guidelines should be examined further.

scholarly journals Treatment Satisfaction Among Clients Enrolled in Methadone Maintenance Treatment (MMT) Program in Myanmar: A Cross-sectional Study

2021 ◽  
Author(s):  
Sun Tun ◽  
B. Vicknasingam ◽  
Darshan Singh
Keyword(s):  
Group Therapy ◽  
Methadone Maintenance Treatment ◽  
Treatment Satisfaction ◽  
Maintenance Treatment ◽  
Methadone Maintenance ◽  
Methadone Treatment ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Satisfaction Scale ◽  
Cross Sectional

Abstract BackgroundTo address the long-standing opioid abuse problem, Myanmar has established the methadone maintenance treatment (MMT) program in 2006. This study aims to determine client’s treatment satisfaction towards MMT program in Myanmar. MethodA total of 210 clients who have registered in MMT program with a minimum of six-month treatment history were recruited for this cross-sectional study across Myanmar. The Verona Service Satisfaction Scale for Methadone-Treatment (VSSS-MT) was administered to objectively measure methadone treatment satisfaction. ResultThe majority (89%, n=186) were satisfied with the current methadone treatment program. Specifically, 89.5% (n=187) claimed to be highly satisfied with the clinic staff professional skills (e.g. doctor, nurse, etc.), (91.9%, n=192) satisfied with the basic interventions (instruction between visits, side-effects etc.), and (74.6%, n=156) satisfied with specific interventions (e.g. individual rehabilitation and psychotherapy, group therapy etc.) categories. Among the different characteristics of the respondents, higher quality of life on physical, psychological, social and environmental categories, respondents who satisfied on current marital status and current leisure status, respondents who were on alcohol were associated with higher treatment satisfaction on methadone (p<0.05). The result of stepwise binary logistic regression showed alcohol use and physical health had significantly association with treatment satisfaction.ConclusionDespite the high methadone treatment satisfaction, treatment providers must make an attempt to address service limitations in order to maintain clients’ participation in MMT program especially for specific intervention categories (e.g. individual rehabilitation and psychotherapy, group therapy etc).

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