Seroprevalence of dengue in blood donors in an outbreak: experience of a blood bank in north India

2019 ◽  
Vol 49 (3) ◽  
pp. 212-215 ◽  
Author(s):  
Ashish Jain ◽  
Sanchit Jain ◽  
Nilotpal Chowdhury
Keyword(s):  
Blood Donors ◽  
Rapid Test ◽  
Cross Sectional Study ◽  
Blood Bank ◽  
North India ◽  
Prevalence Rates ◽  
Sectional Study ◽  
Medical Sciences ◽  
Serum Samples ◽  
Cross Sectional

Our aim was to determine the prevalence of dengue among blood donors at a centre in north India during an outbreak. A retrospective cross-sectional study was conducted using stored serum samples of 369 blood donors at the All India Institute of Medical Sciences (AIIMS), Rishikesh between August and November 2016. Serum samples were tested by an immune-chromatographic rapid test for the screening of dengue markers (IgG/IgM and NS-1). We found prevalence rates of IgG and NS-1 to be 14.9 and 0.54%, respectively.

A descriptive cross-sectional study of Platelets count in apparently healthy Eritrean blood donors attending the National Blood Transfusion Center, Asmara, Eritrea

2020 ◽  
Vol 3 (1) ◽  
pp. 14-17
Author(s):  
Faris Mohamed Awad Abdon ◽  
◽  
Elias Teages Adgoy ◽  
Nahom Yacob Berhane ◽  
Senet Awolker Ibrahim ◽  
...  
Keyword(s):  
Blood Transfusion ◽  
Blood Donors ◽  
Cross Sectional Study ◽  
Blood Bank ◽  
Reference Ranges ◽  
Sectional Study ◽  
Cross Sectional ◽  
Normal Ranges ◽  
The Difference ◽  
Apparently Healthy

Background: Platelets are an important constituent of blood. Safety measures of blood transfusion are important for optimum health environment. To the knowledge of the researchers, there is no study that was conducted concerning Platelets count in apparently healthy Eritrean blood donors. Therefore, this study will help in establishing the reference ranges of Platelets count in them. Objectives: To measure the serum platelets levels and mean platelets volume in apparently healthy Eritrean blood donors attending the national blood bank of Eritrea. Study design: Descriptive crosssectional study. Materials and methods: 610 Blood donors were incorporated in the study. 4 ml of venous blood was collected into K3EDTA tubes (Becton Dickinson, Plymouth, UK) from all of the participants of the study. Blood samples collected into the (EDTA)-tubes were examined for Platelets count and mean platelet volume. Results: The overall mean of platelets count was 267.145 ± (65.915) ×109 /L, The median and mode of values were both 266.3 thousands/mm3. The mean platelet count for the females was 296.122 thousands /mm3, and for males was 252.477 ×109 /L, and the statistic difference between them was significant. The statistic mean of MPV for males was 8.763 fl, and for females was 8.717, and the difference between the two means also considered insignificant. Conclusion: This descriptive cross sectional study was performed in the National Blood bank in Asmara where platelets levels and mean platelets volume were measured for 610 healthy blood donors. The results were found to be within reference normal ranges. The difference between the males and females results was statistically significant

Co-infection of blood borne viruses in blood donors: A cross-sectional study from North India

2017 ◽  
Vol 56 (3) ◽  
pp. 367-370
Author(s):  
Ravi C. Dara ◽  
Aseem K. Tiwari ◽  
Dinesh Arora ◽  
Geet Aggarwal ◽  
Ganesh Singh Rawat ◽  
...  
Keyword(s):  
Blood Donors ◽  
Cross Sectional Study ◽  
North India ◽  
Sectional Study ◽  
Cross Sectional

scholarly journals Trend and prevalence of transfusion transmitted infections among blood donors in rural teaching institute, south India

1970 ◽  
Vol 2 (3) ◽  
pp. 203-206 ◽  
Author(s):  
MS Leena ◽  
Shafee Mohd
Keyword(s):  
Health Center ◽  
Teaching Hospital ◽  
Blood Donors ◽  
South India ◽  
Cross Sectional Study ◽  
Blood Bank ◽  
Sectional Study ◽  
Serological Tests ◽  
Cross Sectional ◽  
Rural Teaching

Background: The magnitude of transfusion transmitted infections (TTI) varies from country to country depending on TTI’s load in that particular population. The aim of the study was to study the trend and prevalence of sero-markers among blood donors in one of the tertiary health center in south India. Materials and Methods: A retrospective cross-sectional study was performed from 2004 to 2010 in a blood bank of teaching hospital in South India. All blood donors who presented to blood bank during the study period were included. Data regarding demography and serological tests were collected on predesigned proforma. Results: There were a total of 6939 blood donors during study period. Out of these, 94(1.35%) were positive for sero-markers for TTIs. The number of blood donors as well as sero-positivity increased from year 2004 to 2010. Conclusions: Trend and sero-prevalence of TTIs increased over period of time. Sero-positivity for TTIs decreased from year 2004 to 2010. DOI: http://dx.doi.org/10.3126/jpn.v2i3.6022 JPN 2012; 2(3): 203-206

scholarly journals Asymptomatic Leishmania infection in blood donors from a major blood bank in Northeastern Brazil: a cross-sectional study

2020 ◽  
Vol 62 ◽  
Author(s):  
Lucas Portela Silva ◽  
Silvia Montenegro ◽  
Roberto Werkauser ◽  
Kamila Gaudêncio da Silva Sales ◽  
Fábia Carla Silva Soares ◽  
...  
Keyword(s):  
Blood Donors ◽  
Cross Sectional Study ◽  
Blood Bank ◽  
Northeastern Brazil ◽  
Leishmania Infection ◽  
Sectional Study ◽  
Cross Sectional

scholarly journals The relative expression of miR-31, miR-29, miR-126, and miR-17 and their mRNA targets in the serum of COVID-19 patients with different grades during hospitalization

2021 ◽  
Vol 26 (1) ◽  
Author(s):  
Reza Keikha ◽  
Seyed Mohammad Hashemi-Shahri ◽  
Ali Jebali
Keyword(s):  
Cross Sectional Study ◽  
Health Centers ◽  
Sectional Study ◽  
Medical Sciences ◽  
Serum Samples ◽  
Cross Sectional ◽  
Relative Expression ◽  
Diagnosis And Prognosis ◽  
Mrna Targets ◽  
Disease Grade

Abstract Background The aim of this study was to evaluate the expression of four up/down-regulated inflammatory miRNAs and their mRNA targets in the serum samples of COVID-19 patients with different grades. Also, we investigated the relative expression of these miRNAs and mRNAs during hospitalization. Methods In this cross-sectional study, 5 mL of blood sample were taken from COVID-19 patients with different grades and during hospitalization from several health centers of Yazd, Tehran, and Zahedan province of Iran from December 20, 2020 to March 2, 2021. The relative expression of miRNAs and mRNAs was evaluated by q-PCR. Results We found that the relative expression of hsa-miR-31-3p, hsa-miR-29a-3p, and hsa-miR-126-3p was significantly decreased and the relative expression of their mRNA targets (ZMYM5, COL5A3, and CAMSAP1) was significantly increased with the increase of disease grade. Conversely, the relative expression of hsa-miR-17-3p was significantly increased and its mRNA target (DICER1) was significantly decreased with the increase of disease grade. This pattern was exactly seen during hospitalization of COVID-19 patients who did not respond to treatment. In COVID-19 patients who responded to treatment, the expression of selected miRNAs and their mRNA targets returned to the normal level. A negative significant correlation was seen between (1) the expression of hsa-miR-31-3p and ZMYM5, (2) hsa-miR-29a-3p and COL5A3, (3) hsa-miR-126-3p and CAMSAP1, and (4) hsa-miR-17-3p and DICER1 in COVID-19 patients with any grade (P  <  0.05) and during hospitalization. Conclusions In this study, we gained a more accurate understanding of the expression of up/down-regulated inflammatory miRNAs in the blood of COVID-19 patients. The obtained data may help us in the diagnosis and prognosis of COVID-19. Trial registration: The ethics committee of Zahedan University of Medical Sciences, Zahedan, Iran. (Ethical Code: IR.ZAUMS.REC.1399.316) was registered for this project.

scholarly journals Serum Concentrations of Selected Organochlorines in Pregnant Women and Associations with Pregnancy Outcomes. A Cross-Sectional Study from Two Rural Settings in Cambodia

2020 ◽  
Vol 17 (20) ◽  
pp. 7652
Author(s):  
Margit Steinholt ◽  
Shanshan Xu ◽  
Sam Ol Ha ◽  
Duong Trong Phi ◽  
Maria Lisa Odland ◽  
...  
Keyword(s):  
Polychlorinated Biphenyls ◽  
Pregnant Women ◽  
Gestational Age ◽  
Low Income ◽  
Cross Sectional Study ◽  
Maternal Serum ◽  
Sectional Study ◽  
Serum Samples ◽  
Cross Sectional ◽  
Rural Settings

We conducted a cross-sectional study among 194 pregnant women from two low-income settings in Cambodia. The inclusion period lasted from October 2015 through December 2017. Maternal serum samples were analyzed for persistent organic pollutants (POPs). The aim was to study potential effects on birth outcomes. We found low levels of polychlorinated biphenyls (PCBs) and organochlorine pesticides (OCP), except for heptachlors, β-hexachlorocyclohexane (HCH), heptachlor epoxide, and p,p’-DDE. There were few differences between the two study locations. However, the women from the poorest areas had significantly higher concentrations of p,p’-DDE (p < 0.001) and hexachlorobenzene (HCB) (p = 0.002). The maternal factors associated with exposure were parity, age, residential area, and educational level. Despite low maternal levels of polychlorinated biphenyls, we found significant negative associations between the PCB congeners 99 (95% CI: −2.51 to −0.07), 138 (95% CI: −1.28 to −0.32), and 153 (95% CI: −1.06 to −0.05) and gestational age. Further, there were significant negative associations between gestational age, birth length, and maternal levels of o,p’-DDE. Moreover, o,p’-DDD had positive associations with birth weight, and both p,p’-DDD and o,p’-DDE were positively associated with the baby’s ponderal index. The poorest population had higher exposure and less favorable outcomes.

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