Extraosseous Ewing Sarcoma: Expanding the Differential Diagnosis of Supraclavicular Fossa Tumors

2017 ◽  
Vol 96 (1) ◽  
pp. E29-E32 ◽  
Author(s):  
Julio Rama-López ◽  
Rafael Ramos Asensio ◽  
Cesar García-Garza ◽  
Pablo Luna Fra ◽  
Maria del Carmen Gassent Balaguer ◽  
...  

A broad spectrum of diseases can be included in the differential diagnosis of neck masses. We report a case of extraosseous Ewing sarcoma that presented as a neck mass in a 70-year-old man. To the best of our knowledge, this is the first reported case of extraosseous Ewing sarcoma of the supraclavicular fossa. Published cases of extraosseous Ewing sarcoma in the neck have been described in other age groups, but those tumors were confined to the parapharyngeal space. Also, there have been reported cases in patients older than 70 years in which Ewing sarcoma affected other structures such as the larynx and the pelvis, but none in the soft tissues of the neck. This case adds extraosseous Ewing sarcoma as a possible diagnosis to consider when evaluating a neck mass in the supraclavicular fossa.

Author(s):  
Jibril Yahya Hudise ◽  
Khalid Ali Alshehri ◽  
Radeif Eissa Shamakhey ◽  
Ali Khalid Alshehri

<p class="abstract"><strong>Background:</strong> <span lang="EN-IN">Neck masses are a common complaint in children worldwide, and constitute a major indication for surgical consultation in many pediatric surgical centers. Most of the neck masses in children are benign in their nature and clinical course. The broad spectrum of etiology of neck masses that ranged from congenital benign to acquired neoplastic lesions is varied and related to multiple factors. This retrospective study was done with the objective to assess the distribution of neck masses related to gender, age, pathology, and anatomical location of neck masses in Aseer Central Hospital. </span></p><p class="abstract"><strong>Methods:</strong> <span lang="EN-IN">Medical records of 62 patients with neck masses were collected from the department of pathology at Aseer Central Hospital KSA. The cases were reviewed for data on gender, age, the type of origin tissue, the type of lesion, and the anatomical location. Comparison between genders, age groups, and tissue origins were performed. All statistical tests were performed with SPSS software. We exclude thyroid, parathyroid and salivary gland masses.  </span></p><p class="abstract"><strong>Results:</strong> <span lang="EN-IN">Over a period of 5 years, a total of 62 patients 53.2% and women 46.8% had neck masses resected for pathological assessments. The age of presentation was ranging from 1 to 14 years. 22.6% developed in (from 1 years to 5 years old), 38.7% developed in (6 to 10 years), and 38.7% developed, in (11 to 14 years). The histopathological diagnosis of the neck masses were congenital 40.3%, inflammatory 33.9%, and malignant tumor 25.8%. </span></p><p class="abstract"><strong>Conclusions:</strong> <span lang="EN-IN">The differential diagnosis of the pediatric neck mass includes a wide array of congenital, inflammatory, benign and malignant lesions. The exact diagnosis may only be obtained by histopathological examination. In our study the most common masses in pediatric patient thyroglossal duct cyst, all midline masses are congenital.</span></p>


2014 ◽  
Vol 3 (3) ◽  
Author(s):  
Tae-Kyung Yoo ◽  
Soo-Hong Kim ◽  
Hyun-Young Kim ◽  
Kwi-Won Park

Branchial cleft anomalies are an important differential diagnosis in congenital neck masses in infants. The third and fourth branchial anomalies are rare branchial cleft anomalies, which are hard to differentiate. We report here an uncommon case of the fourth branchial anomaly that was presented as an asymptomatic neck mass in a neonate.


2005 ◽  
Vol 71 (12) ◽  
pp. 1051-1054 ◽  
Author(s):  
Evan B. Goldstein ◽  
Richard H. Savel ◽  
Filiz Sen ◽  
Peter Shamamian

Neck masses, frequently encountered by physicians, comprise a vast range of diagnoses, with malignancy being the greatest concern. Calcifying fibrous pseudotumor (CFP) is a rare lesion with unknown pathogenesis, characterized pathologically by a predominance of abundant hyalinized collagenous tissue with focal lymphoplasmacytic infiltrate and psammomatous or dystrophic calcifications. We present the case of a 29-year-old woman who presented with a 4-cm left neck mass, accompanied by constitutional symptoms of vague weakness and lethargy. After the lesion failed to respond to a course of antibiotic therapy, fine-needle aspiration was performed, the pathology of which was indeterminate. The concern was that the lesion was a lymphoproliferative disorder–further workup was performed. CT of the chest, abdomen, and pelvis revealed no evidence of adenopathy or neoplasms. Subsequently, an incisional biopsy was performed, suggesting a diagnosis of CFP. Magnetic resonance imaging with contrast, performed to delineate the anatomy, revealed the lesion in the left neck, deep to the left clavicle, that extended superiorly into the supraclavicular fossa. Complete surgical removal of the lesion was successfully performed, with immunophenotyping confirming the initial diagnosis of CFP. We present a case report of cervical CFP, discuss the approach to neck masses, and review the recent literature on this rare, benign entity.


2021 ◽  
Vol 14 (9) ◽  
Author(s):  
Ahmad R Mafi ◽  
Hasan Barati ◽  
Keyvan Ramezani

Introduction: Extraosseous Ewing sarcomas (EESs) are rare tumors that originate from soft tissues. Upper extremity EESs account for about 3% of all cases. Here we reported a case of ESS of the upper limb whose management became complicated due to the COVID-19 pandemic. Case Presentation: A 27-year-old female with EES of the right deltoid region presented after 3 months delay when the tumor had reached a huge size. Neoadjuvant therapy was initiated for her with acceptable results, however, her surgical treatment was postponed 3 times due to the cancellation of elective operations in the hospital as well as her involvement with COVID-19 infection. She developed multiple pulmonary metastases shortly after the surgery and passed away within a fortnight due to respiratory complications. Conclusions: Although not “emergent” by definition, surgical treatment of patients with cancer, especially those who suffer from malignancies with high metastatic potential such as Ewing sarcoma (including EES), should not be considered as “elective” since the disease may progress in a short time and become incurable.


2011 ◽  
Vol 126 (1) ◽  
pp. 97-99 ◽  
Author(s):  
A C Chu ◽  
A Mlikotic ◽  
M A R St John

AbstractIntroduction:True benign thyroid masses very rarely present as a solitary lateral neck mass. Different aetiological mechanisms have been proposed for such masses.Case report:We report a case of thyroid follicular adenoma that presented as a lateral neck mass.Discussion:Ectopic thyroid tissue and metastases from primary thyroid carcinoma should always be considered in the differential diagnosis of lateral neck masses. Complete investigation should include complete blood tests to characterise the orthotopic thyroid gland.


2013 ◽  
Vol 2013 ◽  
pp. 1-4 ◽  
Author(s):  
Vijendra Shenoy ◽  
M. Panduranga Kamath ◽  
Mahesh Chandra Hegde ◽  
Raghavendra Rao Aroor ◽  
Vijetha V. Maller

Introduction. Thymic cysts are among the rarest cysts found in the neck. Nests of thymic tissue may be found anywhere along the descent of the thymic primordia from the angle of the mandible to the mediastinum. Mediastinal extension is seen in 50% of cervical thymic cysts.Case Report. We report an uncommon case of a 15-year-old male, who noted a painless, growing mass on left side of his neck of one-year duration. Computerised tomographic scan showed a multiloculated fluid density lesion with enhancing septae in the left parapharyngeal space, extending from the level of mandible up to C7 vertebral level. Here, we discuss the surgical aspect, histopathology, and management of this rare lateral neck swelling.Discussion. Clinically, in most cases, cervical thymic lesions present as a unilateral asymptomatic neck mass, commonly on the left side of the neck, and 75% of patients present before 20 years of age.Conclusion. Thymic cyst should be included as differential diagnosis of cystic neck masses. Greater awareness among the pathologists may decrease misdiagnosis.


1981 ◽  
Vol 95 (10) ◽  
pp. 1041-1047 ◽  
Author(s):  
B. S. Solem ◽  
K. E. Schrøder ◽  
I. W. S. Mair

AbstractThe differential diagnoses and the duration of symptoms are presented for a group of 288 patients encountered over a ten-year period with a mass in the region of the neck behind and below the angle of the mandible. While infections constituted the largest aetiological group (48·3 per cent), 109 cases (37·9 per cent) had some form of neoplasia, with malignancy being found in 48 (16·6 per cent). The duration of symptoms varied widely, only the acute infections having an acceptably short delay prior to hospital admission. The mean symptom duration for all the neoplastic cases was in excess of five months.The patient with a lump in the neck is a frequently encountered problem in ear, nose and throat practice. An important precept, which has long been recognized in the literature, is that any persistent asymmetrical mass in the neck of an adult must be regarded as malignant until definite proof to the contrary is obtained (Martin and Romieu, 1952; Slaughter et al., 1956; Skolnik et al., 1965; Shaw, 1976). Differential diagnostic possibilities in all age groups are however numerous, and pre-operative conclusions must often be revised following histopathological examination. A simple and rational approach, which is frequently of considerable value in the clinical assessment of these patients, is a combination of topographical and temporal classifications.In 1960, Skandalakis et al. proposed a rule-of-7, in which the average duration of symptoms for cervical masses caused by infections was 7 days; for neoplasms, 7 months; while an interval of 7 years was characteristic of developmental anomalies. The topographical approach involves subdividing the neck into anatomical regions. The most posterior area, covered by the trapezius muscle is, in this context, of minimal clinical interest, since the overwhelming majority of neck masses lies anterior to this muscle. The clinically important part of the neck is subdivided into the anterior and posterior triangles by the sternocleidomastoid muscle. The posterior triangle is much less frequently the site of a neck mass, although malignancy is relatively more common in this region (Moussatos and Baffes, 1963). The anterior triangle is further subdivided by the digastric and omohyoid muscles into four smaller triangles, readily recognizable in the living neck, since both muscles are attached to the hyoid bone which can be palpated in the vast majority of cases.The thyroid and submandibular glands are the most frequent source of neck masses in the inferior carotid, or muscular, and the digastric triangles respectively, and involvement of these organs can usually be readily recognized in the clinic (Beahrs, 1955; Slaughter et al., 1956; Skandalakis et al., 1960). The small submental triangle contains few structures of importance, and the majority of swellings in this region are either thyroglossal cysts or enlarged lymph nodes.The situation is radically different in the carotid triangle, the region of the neck posterior and inferior to the angle of the mandible, where a wide variety of anatomical structures is congregated, and the differential diagnostic possibilities are consequently greater. The present study is a review of swellings in the neck confined to this area.


2020 ◽  
Author(s):  
Gerard M. Doherty

The evaluation of any neck mass begins with a careful, directed history focused on an appropriate differential diagnosis. Directed questions can narrow the diagnostic possibilities and focus subsequent investigations. For example, in younger patients, one might have an initial suspicion of congenital or inflammatory lesions, whereas in older adults, the primary concern is often neoplasia. The head and neck examination is challenging because much of the area to be examined is not easily seen. Patience and practice are necessary to master the special instruments and techniques of examination. Most neck masses in adults are abnormal and are often manifestations of underlying conditions that require treatment. In most cases, therefore, further diagnostic evaluation should be pursued. This review covers clinical evaluation, developing a differential diagnosis, investigative studies, and management of specific disorders associated with neck mass. Figures show cervical lymph nodes, a management algorithm for thyroid nodules, and the course of the thyroglossal duct from the foramen cecum to the pyramidal lobe of the thyroid gland. Tables list the etiology of neck mass, classification of cervical lymph nodes, and sonographic findings and size indications of biopsy of thyroid nodules. This review contains 4 figures, 9 tables, and 8 references. Key words: cervical adenopathy; cervical lymph nodes; congenital neck mass; enlarged lymph nodes; fine-needle aspiration; neck mass; thyroid disease; thyroid mass; thyroid nodule


2018 ◽  
Vol 27 (1) ◽  
pp. 8-8 ◽  
Author(s):  
Ilan Kent ◽  
Evgeny Edelstein ◽  
Olga Levin ◽  
Yaron Wiener

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2020 ◽  
Vol 63 (5) ◽  
pp. 26-30
Author(s):  
Paloma Pérez Ladrón de Guevara ◽  
Georgina Cornelio Rodríguez ◽  
Oscar Quiroz Castro

Fournier’s Gangrene is a type II necrotizing fascitis that leads to thrombosis of small subcutaneous vessels and spreads through the perianal and genital regions and the skin of the perineal. Most cases have a perianal or colorectal focus and in a smaller proportion it originates from the urogenital tract. The mortality rate varies between 7.8 and 50%1-3, only timely diagnosis decreases the morbidity and mortality of this condition. Treatment includes surgical debridement of all necrotic tissue and the use of broad-spectrum antibiotics. Key words: Fournier’s gangrene; gangrene; necrotizing fasciitis; infectious necrotizing of soft tissues.


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