scholarly journals Septal Nasal Extramedullary Plasmacytoma: A Rare Tumor in an Unusual Area

2020 ◽  
pp. 014556132091173
Author(s):  
Arianna Di Stadio ◽  
Massimo Ralli ◽  
Daniela Messineo ◽  
Giuseppe Ciancia ◽  
Annamaria Cascone ◽  
...  

We present an extreme rare case of extramedullary nasal plasmacitoma that arise from nasal septum. The mass surgically removed was analyzed by a pathologist who diagnosed an extramedullary nasal plasmacytoma. The patient did not present systemic involvement. A short cycle of radiotherapy was performed after the surgery. At 9-month follow-up, the patient is recurrence free.

2018 ◽  
Vol 2018 ◽  
pp. 1-7
Author(s):  
James H. Kim ◽  
Nathan Tu ◽  
Bozena Barbara Wrobel

Objectives. To describe a rare case of a paraganglioma arising from the nasal septum and review the diagnosis and management of paragangliomas in the nasal cavity and paranasal sinuses.Methods. We present a case of a 70-year-old female presenting with persistent nasal congestion and obstruction. Nasal endoscopy revealed a posterior septal mass approaching the sphenoid sinuses and partially obstructing the nasopharynx. A biopsy of the mass was taken, and histologic analysis confirmed a diagnosis of paraganglioma.Results. The patient underwent an endoscopic resection of the tumor. There has been no evidence of disease recurrence after 3 months of follow‐up.Conclusions. Paragangliomas arising from the nasal septum are exceedingly rare, but should be considered in the differential diagnosis in patients presenting with nasal septal masses. These tumors are typically benign, although few cases of malignant sinonasal paragangliomas have been reported. Treatment requires surgical excision with close follow-up as several cases of tumor recurrence have been reported.


2005 ◽  
Vol 84 (11) ◽  
pp. 720-722 ◽  
Author(s):  
Byoung J. Baek ◽  
Seong W. Kim ◽  
Hoon Park ◽  
Jin K. Park ◽  
Kyung Y. Han ◽  
...  

We report a rare case of extramedullary plasmacytoma of the nasal septum in a 65-year-old woman. She presented with a 2-month history of left-sided nasal obstruction and intermittent blood-tinged nasal crusting. Nasal endoscopy revealed that a dark-red mass had arisen from the nasal septum; no evidence of invasion to adjacent tissues was seen. A biopsy specimen was diagnosed as a plasmacytoma (kappa light chain—type). Serum and urine electrophoresis failed to detect any myeloma component or Bence Jones protein. All other screening tests to rule out multiple myeloma were negative. These findings confirmed the diagnosis of extramedullary plasmacytoma. The mass was completely removed via an endoscopic approach. No recurrence was noted at the 2-year follow-up.


2020 ◽  
Vol 13 (9) ◽  
pp. e234478
Author(s):  
Hannes Hermann Brandt ◽  
Steffi Johanna Brockmeier ◽  
Nora Tetter

Solitary extramedullary plasmacytoma (SEP) of the larynx is a rare haematological malignancy and an infrequent cause of persisting dysphonia. We present the case of a 54-year-old woman with a long-standing history of dysphonia. While clinical examination showed a rather inconspicuous prominent right vestibular fold, an MRI revealed a laryngeal mass with erosion of the thyroid cartilage. A biopsy taken during rigid endoscopy demonstrated plasma cell infiltration with light chain restriction amidst amyloid deposits. After exclusion of systemic involvement, the diagnosis of an SEP of the larynx with secondary amyloidosis was made. The patient received primary radiation therapy. Another biopsy taken 3 months after the end of therapy did not show any signs of ongoing neoplastic plasma cell disease. The patient was therefore considered to be in remission. She is currently receiving regular follow-up and has not shown signs of persistent or progressive disease for the past 18 months.


2013 ◽  
Vol 70 (2) ◽  
pp. 221-224 ◽  
Author(s):  
Branislav Belic ◽  
Slobodanka Mitrovic ◽  
Snezana Arsenijevic ◽  
Ljiljana Erdevicki ◽  
Jasmina Stojanovic ◽  
...  

Introduction. Plasmacytomas are malignant tumors characterized by abnormal monoclonal proliferation of plasma cells. They originate in either bone - solitary osseous plasmacytoma, or in soft tissue - extramedullary plasmacytoma (EMP). EMP represents less than 1% of all head and neck malignancies. Case report. We presented a case of EMP of the nasal septum in a 44-year-old male who had progressive difficulty in breathing through the nose and frequent heavy epistaxis on the right side. Nasal endoscopy showed dark red, soft, polypoid tumor in the last third of the right nasal cavity arising from the nasal septum. The biopsy showed that it was plasmacytoma. Bence Jones protein in the urine, serum electrophoresis, bone marrow biopsy, skeletal survey and other screening tests failed to detect multiple myeloma. This confirmed the diagnosis of EMP. The mass was completely removed via an endoscopic approach, and then, 4 week later, radiotherapy was conducted with a radiation dose of 50 Gray. No recurrence was noted in a 3-year follow- up period. Conclusion. EMP of the nasal cavity, being rare and having long natural history, represents a diagnostic and therapeutic challenge for any ear, nose and throat surgeon. Depending on the resectability of the lesion, a combined therapy is the accepted treatment.


2008 ◽  
Vol 122 (9) ◽  
Author(s):  
H E Ozel ◽  
G Ergul ◽  
O E Gur ◽  
S Kulacoglu ◽  
C Ozdem

AbstractObjective:We report a rare case of sialadenoma papilliferum.Method:A case report of sialadenoma papilliferum is presented.Results:A 67-year-old woman presented with recurrent epistaxis. She was found to have an exophytic, well circumscribed mass on the nasal septum mucosa. The lesion was completely excised. A diagnosis of sialadenoma papilliferum was made based on the characteristic histological pattern. Follow up showed no evidence of recurrence. Subsequently, the patient remained well without complaint of epistaxis.Conclusion:To our knowledge, this is the first report in the world literature of sialadenoma papilliferum of the nasal cavity. This case indicates that this rare tumour can present with epistaxis, and can be resolved by means of total excision.


2014 ◽  
Vol 21 (3) ◽  
pp. 357-361
Author(s):  
Rakesh Kumar ◽  
Amit Chanduka ◽  
Devendra Purohit ◽  
Radhe Shyam Mittal ◽  
Ronyl Kaushal

Abstract Spinal Teratomas are rare tumor and cervical intramedullary location in infancy still rarer. Only eleven cases of cervical intramedullary teratoma in pediatric patients is reported in available literature (1, ll). We are reporting a case of an infant presenting with cervical mature teratoma with associated dysraphism, adding the next in this rare case series. Arising as a result of dysembryogenesis, these lesions by virtue of their content are difficult to diagnose preoperatively. Heterogeneous intensities on MRI produced by intralesional lipomatous and osseous elements are helpful but rarely enough to diagnose the tumor. Histology is confirmatory. Mature teratomas generally have good prognosis and a timely intervention can prevent further neurological deterioration. However a strict clinical and radiological follow up is recommended.


2021 ◽  
Vol 49 (12) ◽  
pp. 030006052110625
Author(s):  
Yan Liu ◽  
Xiaopei Yuan ◽  
Xiaohong Peng ◽  
Zhiming Xing ◽  
Lisheng Yu

An extramedullary plasmacytoma (EMP) is a rare neoplasm characterized by monoclonal proliferation of plasma cells without features of multiple myeloma. Most EMPs occur in the head and neck region, especially in the aerodigestive tract. We herein report a case of an EMP arising from the nasal inferior turbinate. The mass was surgically removed, and a short cycle of radiotherapy was performed after the surgery. There was no recurrence of the tumor after 1 year of follow-up. These result may be useful for physicians who encounter similar situations in clinical practice.


2018 ◽  
Vol 97 (8) ◽  
pp. E43-E45
Author(s):  
Pratyusha Yalamanchi ◽  
Orly Coblens ◽  
Meejin Ahn ◽  
Steven B. Cannady ◽  
Jason G. Newman

Odontoameloblastoma is an extremely rare tumor derived from odontogenic epithelium and mesenchyme. In the fewer than 20 reported cases, odontoameloblastoma is described as occurring in the maxilla or mandible of young men with a history of unerupted teeth. Here we report a case of a 73-year-old woman who presented to the dentist for routine cleaning and x-rays, which displayed a mandibular lesion. After referral to multiple providers, a biopsy of two involved teeth was obtained and computed tomography of the neck was performed, revealing a large, destructive lesion of the mandible. Histology was consistent with odontoameloblastoma. The patient underwent wide segmental mandibular resection and scapula tip free flap reconstruction. She recovered uneventfully and continues to have close follow-up, given the risk of recurrence. To the best of our knowledge, this is the first reported case of odontoameloblastoma in a patient over age 50. The goal of the authors is to raise awareness of this rare pathology and its diagnostic and management modalities.


2021 ◽  
Vol 9 ◽  
pp. 2050313X2110377
Author(s):  
Yasuhito Nakamura ◽  
Kiyoshi Doi ◽  
Syojiro Yamaguchi ◽  
Etsuji Umeda ◽  
Osamu Sakai ◽  
...  

We reported a rare case of spontaneous frank rupture of a small (4 mm) penetrating aortic ulcer in the ascending aorta resulted in catastrophic bleeding. The ulcer only created a pinhole wound in the adventitia without saccular aneurysms, intramural hematomas, or aortic dissections. Notably, the wound could be directly closed because the aortic wall was intact only 5 mm away from the bleeding site. The postoperative course was uneventful, and the patient was discharged on the 11th postoperative day. After 8 months, follow-up computed tomography showed no abnormality of the aortic wall at the repair site.


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