Otologic Complications of Radiation Therapy

1979 ◽  
Vol 87 (3) ◽  
pp. 359-363 ◽  
Author(s):  
John V. O'Neill ◽  
Arthur H. Katz ◽  
Emanuel M. Skolnik
Keyword(s):  
Radiation Therapy ◽  
External Auditory Canal ◽  
Radiation Dosage ◽  
Preventive Measures ◽  
Contributing Factors ◽  
University Of Illinois ◽  
Nasopharyngeal Tumors ◽  
The University ◽  
Serous Otitis Media

Radiation therapy has proved to be a valuable modality in the management of patients with nasopharyngeal tumors. Routine follow-up of patients in the tumor clinic of the University of Illinois Eye and Ear Infirmary appeared to indicate an increasing incidence of otologic pathology. For this reason, a retrospective study focusing on the otologic findings in patients whose radiation therapy for nasopharyngeal tumors included the external auditory canal, middle ear space, or eustachian tube was performed. The results of this study are discussed in relationship to total radiation dosage, time of survival after therapy, and pretreatment otologic status. The complications covered a spectrum from intermittent serous otitis media to osteoradionecrosis of the external auditory canal. Possible contributing factors are discussed, and preventive measures are suggested.

scholarly journals Visceral non-presence

2020 ◽  
Vol 4 (1) ◽  
pp. 92-100
Author(s):  
Jessica Brinkworth ◽  
Korinta Maldonado ◽  
Ellen Moodie ◽  
Gilberto Rosas
Keyword(s):  
Infection Control ◽  
Processing Plant ◽  
University Of Illinois ◽  
First Case ◽  
Large Outbreak ◽  
Results Management ◽  
The University ◽  
Positive Results

The local slaughterhouse’s coronavirus cluster was the first large outbreak we heard about in Champaign County. The sprawling pork processing plant sits in the midst of cornfields some 17 miles north of the University of Illinois at Urbana-Champaign. Until early May, workers there processed 35 million pounds of pork a month. The company reported its first case on 25 April. Health inspectors arrived two days later to find the plant 90 percent out of compliance in its infection control practices. By 15 May, after testing 200 of the 627 workers for COVID-19, 83 got positive results. Management admitted it was ‘complex’ to track employees being tested and to follow up with those who had to be quarantined. That’s when they contacted the University of Illinois at Urbana-Champaign. They then announced confidently to the local press: We’ve got it under control. We have the scientists now.

Follow-up Observations on 24-Hour Pharmacotherapy Services in the Emergency Department

1992 ◽  
Vol 26 (4) ◽  
pp. 476-480 ◽  
Author(s):  
Nada S. Berry ◽  
Jon E. Folstad ◽  
Jerry L. Bauman ◽  
Jerrold B. Leikin
Keyword(s):  
Emergency Department ◽  
Consultation Service ◽  
University Of Illinois ◽  
Clinical Pharmacists ◽  
Drug Concentrations ◽  
Frequency Of Use ◽  
The University ◽  
Consultation Services ◽  
The Impact

OBJECTIVE: To analyze the impact of 24-hour clinical pharmacy (CP) services in the emergency department (ED). DESIGN: A review of the “on-call report forms” and written consultations provided by CP between July 1985 and December 1987. SETTING: The University of Illinois Hospital. MAIN OUTCOME MEASURES: Patient-related versus non—patient-related cases; solicitor, type of and time per consultation; drug concentration determinations by CP; and comparison with other ED consultation services. RESULTS: Of 3787 consultations 3650 (96 percent) were patient-related, 137 (4 percent) were non—patient-related. Consultations were solicited from another individual in 2774 cases (73 percent); they were initiated by the clinical pharmacists in 831 cases (22 percent). Of the patient-related consultations, 1215 (33.3 percent) involved pulmonary disease, 796 (21.8 percent) toxicology, 635 (17.4 percent) seizures, 411 (11.3 percent) cardiac cases, 268 (7.3 percent) pharmacokinetics, and 325 (8.9 percent) miscellaneous. Consultations were solicited by physicians (1806, 65 percent), nurses (652, 23.5 percent), cardiac arrest page (237, 8.5 percent), patients (45, 2 percent), or pharmacists (34, 1 percent). They averaged 100 minutes each. Of 2197 drug concentrations, 1939 (88 percent) were completed by the clinical pharmacist. Concentrations were obtained for theophylline (1055, 54.4 percent), phenytoin (511, 26.4 percent), phenobarbital (324, 16.7 percent), and acetaminophen (49, 2.5 percent). Compared with other consultation services, CP ranked first in regard to frequency of use. CONCLUSIONS: The CP consultation service in the ED was as well used as most physician consultation services and tended to involve specific therapeutic areas that have implications for the training of emergency department clinical pharmacists.

scholarly journals RARE-25. CLINICAL FEATURES OF PINEAL PARENCHYMAL TUMOR OF INTERMEDIATE DIFFERENTIATION (PPTID): A SINGLE INSTITUTION REVIEW

2019 ◽  
Vol 21 (Supplement_6) ◽  
pp. vi226-vi227
Author(s):  
Katherine Kunigelis ◽  
Bette Kleinschmidt-DeMasters ◽  
D Ryan Ormond
Keyword(s):  
Radiation Therapy ◽  
Progression Free Survival ◽  
Subtotal Resection ◽  
Adjuvant Radiation ◽  
Single Institution ◽  
Craniospinal Radiation ◽  
University Of Colorado ◽  
First Recurrence ◽  
The University

Abstract Pineal parenchymal tumors of intermediate differentiation (PPTID) are rare. Even in the most recent WHO 2016, definitive histological criteria to distinguish grade II from III lesions remain to be defined. While no single institution has large numbers of cases, our experience has been that the clinical course is more varied and complicated than reported. The University of Colorado Health pathology database was queried for cases diagnosed as PPTID, 2006 – 2019, inclusive. Twelve adult patients were identified. Mean age at diagnosis was 40 years (range 26–78). There were 9 female and 3 male patients. Seven patients had well-documented clinical courses at our primary institution. At initial diagnosis, all were treated with surgery and 3/6 documented a gross total resection (GTR). Adjuvant radiation therapy to the resection bed in was administered in 5 of 7 (71%) of patients (4 IMRT, 1 SRS). Mean follow-up time was 71 months (range 13–195); 5/7 (71%) of patients developed a recurrence. Median progression free survival was 37 months (range 13- 73 months), with tendency to be longer for male gender (57.5 versus 17 months in females, p=0.17), and GTR (40 months versus 16 months in subtotal resection, p=0.49). Eighty percent of first recurrent disease had leptomeningeal dissemination. First recurrences were treated with radiation alone in 3 (60%) patients (1 SRS, 1 IMRT), craniospinal radiation with multi-agent chemotherapy in 1 (20%) patient, and surgery with radiation therapy in 1 (20%). At last follow-up, 2 patients (28.5%) had died, with median OS of 168.5 months. Although PPTIDs have a known potential for local recurrence and craniospinal dissemination (quoted as 22% and 10%, respectively in WHO 2016), our data show a more dismal experience with 71% recurrence and 80% dissemination at first recurrence. Lack of standardized therapies results in challenges in individual patient management.

scholarly journals Development, implementation, and evaluation of a Community Engagement Advisory Board: Strategies for maximizing success

2018 ◽  
Vol 2 (1) ◽  
pp. 8-13 ◽  
Author(s):  
Alicia K. Matthews ◽  
Susan Newman ◽  
Emily E. Anderson ◽  
Amparo Castillo ◽  
Marilyn Willis ◽  
...  
Keyword(s):  
Community Engagement ◽  
Online Survey ◽  
Response Rate ◽  
Advisory Board ◽  
Sufficient Information ◽  
Consultation Service ◽  
University Of Illinois ◽  
Evaluation Strategies ◽  
The University

IntroductionThe purpose of this paper is to describe the formation, operation, and evaluation of a Community Engagement Advisory Board (CEAB) that serves as a resource of the University of Illinois at Chicago’s (UIC) Center for Clinical and Translational Sciences (CCTS).MethodsCurrent CEAB roles and functions, operating procedures for research consultations and program evaluation strategies were described. Investigators receiving a consultation from 2009 to 2017 (n=91, response rate 78%) were surveyed via an online survey immediately after the consultation and at 12-month follow-up.ResultsOverall, CEAB members were viewed as having sufficient information (92%) and expertise (79%) to provide consultation. Satisfaction levels with the specific consultation received and the overall consultation service were high. The majority of investigators indicated that they would come back to the CEAB for a future consultation, if needed, and would recommend a consultation to others (93% and 96%, respectively). At 12-months, 87% of respondents indicated they had implemented at least some of the recommendations received and 93% said that the consultation influenced their subsequent research.ConclusionsData from recent annual evaluations highlight the benefits of CEAB for consulting investigators. Our model can be used to inform the development of future CEAB boards.

Cranial Chordomas: Clinical Presentation and Results of Operative and Radiation Therapy in Twenty-six Patients

Neurosurgery ◽  
1985 ◽  
Vol 17 (5) ◽  
pp. 703-710 ◽  
Author(s):  
Corey Raffel ◽  
Donald C. Wright ◽  
Philip H. Gutin ◽  
Charles B. Wilson
Keyword(s):  
Radiation Therapy ◽  
San Francisco ◽  
Clinical Presentation ◽  
Average Length ◽  
Heavy Charged Particles ◽  
Presenting Symptoms ◽  
Average Survival ◽  
The University ◽  
Lost To Follow Up

Abstract The clinical presentation and the results of operative and radiation therapy in a series of 26 patients with cranial chordomas seen at the University of California, San Francisco, between 1940 and 1984 are reviewed. There were 14 men and 12 women, with a mean age of 39.6 years. Six patients had chondroid chordomas. The most common presenting symptoms were headache and diplopia, and the most common presenting sign was extraocular palsy. Fifty-three operations directed at removal of the tumor were performed. Twenty-three patients received various forms of radiation therapy postoperatively, including conventional external beam therapy, heavy charged particles, and interstitial implants. The average length of follow-up is 5.6 years. Eleven of 26 patients have died; the mean duration of survival in this group, excluding 1 perioperative death, was 4 years and 2 months. Although the average survival time of 6 years and 4 months was the same in patients with typical chordomas (excluding the perioperative death and 1 patient lost to follow-up) and in those with the chondroid variant, all of the latter are still alive, whereas more than half of the patients with typical chordoma have died.

Angiographic features of “brain sag”

2011 ◽  
Vol 115 (3) ◽  
pp. 586-591 ◽  
Author(s):  
Ali Alaraj ◽  
Troy Munson ◽  
Sebastian R. Herrera ◽  
Victor Aletich ◽  
Fady T. Charbel ◽  
...  
Keyword(s):  
Basilar Artery ◽  
Cerebral Arteries ◽  
University Of Illinois ◽  
Ruptured Aneurysms ◽  
Lumbar Drain ◽  
Blood Patch ◽  
The University ◽  
The Brain ◽  
Angiographic Findings

Object Cerebrospinal fluid hypotension, or “brain sag,” is a recently described phenomenon most commonly seen following craniotomy for the clipping of ruptured aneurysms along with preoperative lumbar drain placement. The clinical features and CT findings have been previously described. Clinical presentation can be similar to and often mistaken for cerebral vasospasm. In this study, the authors report on the angiographic findings in patients with brain sag. Methods Five cases of brain sag were diagnosed (range 1–4 days) after the surgical treatment of ruptured aneurysms at the University of Illinois at Chicago. All patients met the clinical and CT criteria for brain sag. Admission cerebral angiograms and subsequent angiograms during symptoms of brain sag were obtained in all patients. In 3 patients, angiography was performed after the resolution of symptoms. Results In all 5 patients, the level of the basilar artery apex was displaced inferiorly with respect to the posterior clinoid processes during brain sag. This displacement was significant enough to create a noticeable kink in the basilar artery (“cobra sign”) in 3 patients. Other angiographic findings included foreshortening or kinking of the intracranial vertebral artery. In all patients, the posterior cerebral arteries were displaced medially and inferiorly. Three patients were treated for simultaneous severe radiological vasospasm. In 4 patients, the brain sag was recognized, and the patients' conditions improved when they were placed flat or in the Trendelenburg position, at times combined with an epidural blood patch. Patients with follow-up angiography studies after the symptoms had resolved displayed a reversal of the angiographic features. Conclusions Brain sag appears to be associated with characteristic angiographic features. Recognizing these features may help to diagnose brain sag as the cause of neurological deterioration in this patient population.

Five Decades of Research Experience in Speech Anatomy and Physiology

2016 ◽  
Vol 1 (5) ◽  
pp. 4-12
Author(s):  
David P. Kuehn
Keyword(s):  
Ohio State University ◽  
State University ◽  
Research Experience ◽  
University Of Iowa ◽  
University Of Illinois ◽  
Anatomy And Physiology ◽  
The Ohio State University ◽  
Speech Science ◽  
The University ◽  
East Carolina University

This report highlights some of the major developments in the area of speech anatomy and physiology drawing from the author's own research experience during his years at the University of Iowa and the University of Illinois. He has benefited greatly from mentors including Professors James Curtis, Kenneth Moll, and Hughlett Morris at the University of Iowa and Professor Paul Lauterbur at the University of Illinois. Many colleagues have contributed to the author's work, especially Professors Jerald Moon at the University of Iowa, Bradley Sutton at the University of Illinois, Jamie Perry at East Carolina University, and Youkyung Bae at the Ohio State University. The strength of these researchers and their students bodes well for future advances in knowledge in this important area of speech science.

Prospective evaluation for gastrointestinal bleedings at the University Hospital St. Pölten – one year of follow-up

2019 ◽  
Author(s):  
M Stättermayer ◽  
F Riedl ◽  
S Bernhofer ◽  
A Stättermayer ◽  
A Mayer ◽  
...  
Keyword(s):  
University Hospital ◽  
Prospective Evaluation ◽  
One Year ◽  
The University

University Geographies and Folk Music Landscapes

2016 ◽  
Vol 33 (1) ◽  
pp. 92-116 ◽  
Author(s):  
David K. Blake
Keyword(s):  
Mass Culture ◽  
Folk Music ◽  
Traditional Music ◽  
Rural Landscape ◽  
Power Structures ◽  
Distant Object ◽  
University Of Illinois ◽  
Liberal Politics ◽  
Cultural Form ◽  
The University

By examining folk music activities connecting students and local musicians during the early 1960s at the University of Illinois at Urbana-Champaign, this article demonstrates how university geographies and musical landscapes influence musical activities in college towns. The geography of the University of Illinois, a rural Midwestern location with a mostly urban, middle-class student population, created an unusual combination of privileged students in a primarily working-class area. This combination of geography and landscape framed interactions between students and local musicians in Urbana-Champaign, stimulating and complicating the traversal of sociocultural differences through traditional music. Members of the University of Illinois Campus Folksong Club considered traditional music as a high cultural form distinct from mass-culture artists, aligning their interests with then-dominant scholarly approaches in folklore and film studies departments. Yet students also interrogated the impropriety of folksong presentation on campus, and community folksingers projected their own discomfort with students’ liberal politics. In hosting concerts by rural musicians such as Frank Proffitt and producing a record of local Urbana-Champaign folksingers called Green Fields of Illinois (1963), the folksong club attempted to suture these differences by highlighting the aesthetic, domestic, historical, and educational aspects of local folk music, while avoiding contemporary socioeconomic, commercial, and political concerns. This depoliticized conception of folk music bridged students and local folksingers, but also represented local music via a nineteenth-century rural landscape that converted contemporaneous lived practice into a temporally distant object of aesthetic study. Students’ study of folk music thus reinforced the power structures of university culture—but engaging local folksinging as an educational subject remained for them the most ethical solution for questioning, and potentially traversing, larger problems of inequality and difference.

Sign in / Sign up

Export Citation Format

Share Document