Normal Nasal Resistance

1985 ◽  
Vol 93 (6) ◽  
pp. 778-785 ◽  
Author(s):  
John F. Pallanch ◽  
Thomas V. McCaffrey ◽  
Eugene B. Kern

Eighty normal adults without nasal symptoms were studied to determine normal nasal resistance values and the variation of nasal resistance in normal adults. A microprocessor-based system for collection and analysis of transnasal pressure and flow was used to obtain nasal resistance values. Unilateral and total transnasal pressure and flow values were determined before and after decongestion of the nose with 1% phenylephrine spray. The distribution of the 80 resistance values was found to be skewed to the right. Log transformation of the resistance values was the best method to normalize their distribution. The mean and variation of normal nasal resistance are reported at flows of 0.1 and 0.2 L/sec, at pressures of 0.5 and 1 cm H2O, and at radii of 1, 2, and 3 on the pressure-flow curve.

2020 ◽  
pp. 112070002093663
Author(s):  
Henrik C Bäcker ◽  
David Krüger ◽  
Sophie Spies ◽  
Carsten Perka ◽  
Stephanie M Kirschbaum ◽  
...  

Introduction: The correct moment for return to driving after total hip arthroplasty (THA) remains unclear. Until today no uniform recommendation exists on the ability to perform an emergency brake. The aim of this prospective study was to investigate the braking ability of patients before and after THA implantation based on brake reaction time in milliseconds (BRT) and braking force in N (BF). Methods: In total, 25 patients (15 men, 10 women, mean age 51.3 ± 10.1 years) were treated with THA on the right side. Inclusion criteria consisted of a valid driving licence, frequent road participation and at least 2 years of driving experience. Exclusion criteria were underlying neurological disorders as well as severe complaints in the lumbar spine and the right knee joint. The brake ability was evaluated for emergency braking with a car simulator and a measuring sole. Measurements were performed preoperatively, 6 days, 2, 4 and 6 weeks after surgery. Results: Preoperatively, the mean BRT was 671.3 ± 123.5 ms and the BF 455.4 ± 185.0 N. Significant differences were observed at 6 days and 2 weeks after surgery, (BRT 836.4 ± 219.7 ms, respectively, BRT 735.0 ± 186.7 ms, and BF 302.6 ± 154.9 N, respectively, BF 375.5 ± 149.3 N, p < 0.05). Only 4 weeks after, no significant differences were seen compared to pre-operative with a BRT of 647.0 ± 91.9ms ( p = 0.354) and BF of 435.9 ± 177.4 ( p = 0.843). Furthermore, the BRT improved significantly after 6 weeks (607.4 ± 87.6; p = 0.005). Conclusions: The braking force is significantly reduced, and the brake reaction time is prolonged directly after surgery for at least 2 weeks. After 4 weeks, no statistically significant differences were measured, although special care should still be taken during return to activity.


2017 ◽  
Vol 12 (3) ◽  
pp. 310-315 ◽  
Author(s):  
César Meylan ◽  
Joshua Trewin ◽  
Kelly McKean

The aims of the current study were to examine the external validity of inertial-based parameters (inertial movement analysis [IMA]) to detect multiplanar explosive actions during maximal sprinting and change of direction (COD) and to further determine its reliability, set appropriate magnitude bands for match analysis, and assess its variability during international women’s soccer matches. Twenty U20 female soccer players, wearing global positioning system (GPS) units with a built-in accelerometer, completed 3 trials of a 40-m sprint and a 20-m sprint with a change of direction to the right or left at 10 m. Furthermore, 13 women’s national-team players (157 files; 4–27 matches/player) were analyzed to ascertain match-to-match variability. Video synchronization indicated that the IMA signal was instantaneous with explosive movement (acceleration, deceleration, COD). Peak GPS velocity during the 40-m sprint showed similar reliability (coefficient of variation [CV] = 2.1%) to timing gates but increased before and after COD (CV = 4.5–13%). IMA variability was greater at the start of sprints (CV = 16–21%) than before and after COD (CV = 13–16%). IMA threshold for match analysis was set at 2.5 m · s–1 · s–1 by subtracting 1 SD from the mean IMA during sprint trials. IMA match variability (CV = 14%) differed from high-speed GPS metrics (35–60%). Practitioners are advised that timing lights should remain the gold standard for monitoring sprint and acceleration capabilities of athletes. However, IMA could be a reliable method to monitor explosive actions between matches and assess changes due to various factors such as congested schedule, tactics, heat, or altitude.


2017 ◽  
Vol 8 (1) ◽  
pp. 91-98 ◽  
Author(s):  
Tadashi Matsumoto ◽  
Takashi Itokawa ◽  
Tomoaki Shiba ◽  
Kotaro Hine ◽  
Yuichi Hori

Background: The dilation of veins and tortuosity of arteries that occur in retinopathy of prematurity (ROP) are improved by therapy, and thus posttherapy changes in ocular circulation are also conceivable. We report a case of ROP in which we were able to measure the ocular circulation before and after photocoagulation therapy, using a laser speckle flowgraphy (LSFG) system that is modified for neonates. Case Report: A female infant was born at 25 weeks’ gestation with a birth weight of 808 g. We performed photocoagulation in both eyes at age 15 weeks, and we measured the ocular circulation with the “LSFG-baby” system before and at 12 weeks after the photocoagulation treatment. We also measured the mean blur rate (MBR) in the optic nerve head (ONH) and the relative flow volume (RFV) in the retinal vessels, and we examined the change rates from before to after treatment. The changing rate of the MBR-A (the mean of all values) in the ONH in the right and left eyes was 76.5 and 98.5%, respectively. The vascular RFV in the severe dilation and tortuosity quadrant also tended to decrease. Conclusions: Photocoagulation improved the dilation of veins and tortuosity of arteries and reduced the ocular blood flow in this neonate with ROP. The LSFG-baby system effectively and directly revealed the optic nerve and retinal blood vessels.


2016 ◽  
Vol 24 (3) ◽  
pp. 367-369 ◽  
Author(s):  
Ozgur Karakoyun ◽  
Ertan Sahin ◽  
Mehmet Fatih Erol ◽  
Mesut Kariksiz ◽  
Metin Kucukkaya

Purpose To evaluate changes in blood circulation of the femoral cortex in rabbits using scintigraphy before and after cable cerclage alone or combined with an intramedullary Kirschner wire. Method Ten New Zealand rabbits were used. For the right femur, a 2-mm-thick cable was placed around the mid-diaphyseal region and squeezed with a 400-N force and locked with a clip. For the left femur, a 1.8-mm Kirschner wire was inserted retrogradely into the medullary canal, and a 2-mm-thick cable was applied using the same technique. The blood perfusion ratio of the region of interest (ROI) before and after surgery was evaluated using scintigraphy. Results For the right femurs, the mean ROI perfusion ratio decreased by 45% from 2.51 to 1.37 after intervention (p=0.001). For the left femurs, the mean ROI perfusion ratio decreased by 56% from 2.12 to 0.92 after intervention (p<0.001). The mean ROI perfusion ratio post-intervention was higher in the right than left femurs (p=0.017). Conclusion Cable cerclage around the femoral cortex significantly decreased blood circulation in the area.


1991 ◽  
Vol 71 (6) ◽  
pp. 2317-2324 ◽  
Author(s):  
J. R. Wheatley ◽  
T. C. Amis ◽  
L. A. Engel

We examined the inspiratory and expiratory pressure-flow relationships of both the oral and nasal airways before and after exercise in normal upright subjects. With the use of a partitioned facemask, nasal resistance was measured using posterior rhinomanometry, and oral resistance was measured by recording transoral pressure during oral breathing. Both the nasal and oral pressure-flow relationships for inspiration and expiration were curvilinear and were well described by a power function of the form delta P = aVb (where P is pressure, V is flow, a and b are constants) (r2 = 0.96 +/- 0.01). The exponent b describes the curvilinearity of the pressure-flow curve and can be used to infer the flow regimen. At rest, the inspiratory nasal and oral curves suggested a similar degree of turbulence (b = 1.77 +/- 0.06 and 1.83 +/- 0.04, respectively). However, inspiratory flow regimens were inferred to be more turbulent than those during expiration both before and after exercise. After exercise, decreases in inspiratory nasal resistance at low flows were associated with a change in flow regimen from fully turbulent to orifice flow over the entire flow range. Thus the application of a power function to nasal and oral pressure-flow data permits representation of the whole relationship and allows insight into the nature of the flow regimens.


2008 ◽  
Vol 33 (1) ◽  
pp. 67-74 ◽  
Author(s):  
G. Farronato ◽  
C. Maspero ◽  
E. Russo ◽  
G. Periti ◽  
D. Farronato

The purpose of this study is to evaluate the usefulness of rapid palatal expansion in growing patients to eliminate the nasal pyramid stenosis as a cause of primary headache. Patients were invited to participate in the clinical study at the University of Milan, Department of Orthodontics. Forty-one growing patients of both genders suffering from primary neurovascular headaches and having transverse maxillary deficiency were studied before and after rapid palatal expansion. A clinical examination, postero-anterior radiography and rhinomanometry were performed. After rapid palatal expansion (RPE) therapy all patients showed a constant and important increase in the values relating to both skeletal and dental structures, a significant reduction in the mean nasal resistance, and a significant decrease or elimination of headache symptoms. This therapy provides a preventive alternative for surgical procedures, such as the neurovascular decompressive septo-ethmoidosphenoidectomy performed in adult patients.


2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
Athar Zareei ◽  
Milad Abdolahian ◽  
Shahram Bamdad

It is important to predict which astigmatic patients require separate refraction for near vision. This study compared cylindrical components changes by cyclopentolate 1% for the low and high amount of astigmatism. The right eyes of 1014 healthy individuals (307 males and 707 females) with cylindrical refractive power more than −0.5 diopter on autorefractometer were selected. Both male and female patients in the age range of 17–45 years were refracted before and after cycloplegia, using 1% cyclopentolate. All volunteers were classified into 2 subgroups including the lower astigmatism group (−2.25 to −0.50) and the higher astigmatic group (−2.50 to over). Alpines’ method was used to compare the effect of cycloplegic drop on cylindrical power. The mean age in the lower astigmatism group (29.58; 95% CI: 29.18 to 29.99 years) was not significantly different from the higher astigmatic group (29.85; 95% CI: 29.07 to 30.62) and there were no significant differences in gender between these two groups ( P = 0.54 ). Differences between wet and dry refraction in J0 (−0.03; 95% CI:−0.06 to −0.008) and J45 (−0.03; 95% CI:−0.06 to −0.01) were significant only in the higher astigmatic group. Axis changes by the cycloplegic drop in the lower astigmatism group were 3.51 (CI: 3.22 to 3.81) and axis changes by the cycloplegic drop in the higher astigmatism group were 2.21 (CI: 1.73 to 2.49). In patients with a lower amount of astigmatism (−2.25 to −0.50), additional near subjective refraction could be done for precise determination of axis and in patients with a higher amount of astigmatism (−2.50 to over), near subjective refraction might be done for precise determination of power.


2021 ◽  
Vol 2021 ◽  
pp. 1-10
Author(s):  
Ling-Chun Wang ◽  
Yi-Hao Lee ◽  
Chi-Yu Tsai ◽  
Te-Ju Wu ◽  
Ya-Ying Teng ◽  
...  

Objective. The aim of this study is to clarify the postsurgical stability of temporomandibular joints in skeletal class III patients treated with 2-jaw orthognathic surgery which was performed utilizing computer-aided three-dimensional simulation and navigation in orthognathic surgery (CASNOS) protocol. Materials and Methods. 23 consecutive nongrowing skeletal class III patients with mandibular prognathism associated with maxillary retrognathism treated with 2-jaw orthognathic surgery between 2018 and 2019 were enrolled in this study. The surgery was planned according to the standardized protocol of CASNOS (computer-aided three-dimensional simulation and navigation in orthognathic surgery). Computed tomography (CT) scans were performed in all patients 3 weeks presurgically and 6 months postsurgically. ITKSNAP and 3D Slicer software were used to reconstruct three-dimensional facial skeletal images, to carry out image segmentation, and to superimpose and quantify the TMJ position changes before and after surgery. Amount of displacement of the most medial and lateral points of the condyles and the change of intercondylar angles were measured to evaluate the postsurgical stability of TMJ. Results. A total amount of 23 skeletal class III patients female : male = 12 : 11 with age ranged from 20.3 to 33.5 years (mean: 24.39 ± 4.8   years   old ) underwent Le Fort I maxillary advancement and BSSO setback of the mandible. The surgical outcome revealed the satisfactory correction of their skeletal deformities. The mean displacement of the right most lateral condylar point (RL-RL ′ ) was 1.04 ± 0.42   mm and the mean displacement of the left most lateral condylar point (LL-LL ′ ) was 1.19 ± 0.41   mm . The mean displacement of the right most medial condylar point (RM-RM ′ ) was 1.03 ± 0.39   mm and the left most medial condylar point (LM-LM ′ ) was 0.96 ± 0.39   mm . The mean intercondylar angle was 161.61 ± 5.08 ° presurgically and 159.28 ± 4.92 ° postsurgically. Conclusion. The postsurgical position of TM joint condyles in our study only presented a mild change with all the landmark displacement within a range of 1.2 mm. This indicates the bimaxillary orthognathic surgery via 3D CASNOS protocol can achieve a desired and stable result of TMJ position in treating skeletal class III adult patients with retrognathic maxilla and prognathic mandible.


Reproduction ◽  
2000 ◽  
pp. 85-94 ◽  
Author(s):  
JJ Dufour ◽  
Y Cognie ◽  
P Mermillod ◽  
JC Mariana ◽  
RF Romain

Endocrine control of follicular growth was studied in mature Romanov ewes carrying (RF+) or not carrying (R+2) the Booroola Fec gene during an oestrous cycle after gonadotrophin-dependent follicles were suppressed by treatment with an antagonist of GnRH (Antarelix, 0.5 mg per day) and superovulatory treatment was administered. The left ovary was removed after 10 days of treatment (saline or Antarelix) and the right ovary was removed at the end of the superovulatory treatment. Ewes of both genotypes treated with Antarelix had lower plasma LH concentrations than did controls from day 0 to day 10. The inhibitory effect of Antarelix on LH concentration increased with day of treatment. The variability in FSH concentrations during the initial 10 days was reduced by Antarelix treatment in both genotypes. Plasma FSH concentrations were higher in RF+ ewes than in R+2 ewes. In both genotypes, FSH concentrations varied significantly with day of treatment, with the lowest concentrations at day 8 and the highest concentrations at day 5. RF+ ewes had a greater total and atretic number of antral follicles 0.62-1.12, 1.12-2.00 and 2.00-3.00 mm in diameter (classes 2, 3 and 4) than did R+2 ewes before and after superovulatory treatment. After superovulatory treatment, the total number of atretic and non-atretic follicles > 3.00 mm in diameter (class 5) increased in both genotypes. Superovulatory treatment also increased the number of total and atretic class 4 follicles in RF+ only. Conversely, superovulatory treatment decreased the mean number of class 3 follicles in both genotypes, while the number of atretic follicles was decreased only in R+2 ewes. Antarelix treatment significantly reduced the percentage of follicles > 2.00 mm in diameter in RF+ but not in R+2 ewes. Antarelix treatment before superovulatory treatment increased the total number of class 4 follicles in both genotypes but the increase was more significant in RF+ than in R+2 ewes. These results indicate that Antarelix pretreatment favours a greater superovulatory response in Romanov ewes carrying the Fec gene because ovulatory follicles are recruited from a wider range of follicular size classes.


2017 ◽  
Vol 6 (4) ◽  
pp. 1-9
Author(s):  
Monika Prus ◽  
Jarosław Wysocki ◽  
Marta Krasny ◽  
Kazimierz Niemczyk

Patients’ subjective assessment of nasal patency often does not correspond to the objective results of functional and imaging examinations. The objective of this study was to identify the rhinometry (AR) and rhinomanometry (RMM) parameters that were best correlated to patients’ self-evaluation of nasal patency before and after nasal airway obstruction surgery. The study material consisted of RMM and AR results as well as SNOT-20 self-evaluation questionnaires completed by 233 patients presenting with rhinological problems and routinely diagnosed at the RMM Lab of the Department and Clinic of Otolaryngology of the Medical University of Warsaw. Data were collected from 70 females (31.4%) aged 18 through 81 years and 153 males (68.6%) aged 16 through 81 years. The results were subjected to statistical analysis by a licensed statistician using the Statistica 10 software package. A statistically significant relationship was demonstrated between the subjective perception of nasal patency and RMM results. The higher the asymmetry of air flow within the left and the right nasal cavity, the higher the perceived restriction of nasal patency. Significant differences were observed between patients reporting maximum discomfort regarding impaired nasal patency and the remaining patients: the former were characterized by nasal resistance values being several-fold higher than that observed in the latter while nearly always improving after nasal airway obstruction surgeries. No significant reflection of patients’ self-evaluation of nasal patency was found in the acoustic rhinometry measurements.


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