Pulmonary aspergilloma: from classification to management

2019 ◽  
Vol 28 (1) ◽  
pp. 33-38 ◽  
Author(s):  
Hicham Harmouchi ◽  
Rabiou Sani ◽  
Ibrahim Issoufou ◽  
Marouane Lakranbi ◽  
Yassine Ouadnouni ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Respiratory Failure ◽  
Clinical Symptoms ◽  
Therapeutic Option ◽  
Severe Respiratory Failure ◽  
Poor General Condition ◽  
Thoracic Computed Tomography ◽  
Life Threatening ◽  
Pulmonary Aspergilloma ◽  
Pulmonary Cavity

Pulmonary aspergilloma is a form of aspergillosis characterized by the colonization of a preexisting pulmonary cavity, most often of tuberculosis origin. Clinical symptoms are predominately hemoptysis that can be life-threatening, and thoracic computed tomography can distinguish simple from complex pulmonary aspergilloma. The best therapeutic option remains surgery which allows surgical resection of the mycetoma and the underlying cavity. Nonsurgical treatment is performed in inoperable patients because of severe respiratory failure or a poor general condition.

Nonventilatory strategies for patients with life-threatening 2009 H1N1 influenza and severe respiratory failure

2010 ◽  
Vol 38 ◽  
pp. e74-e90 ◽  
Author(s):  
Lena M. Napolitano ◽  
Pauline K. Park ◽  
Krishnan Raghavendran ◽  
Robert H. Bartlett
Keyword(s):  
Respiratory Failure ◽  
H1n1 Influenza ◽  
Severe Respiratory Failure ◽  
Life Threatening ◽  
2009 H1n1

scholarly journals ECMO Rescues Patients With Acute Respiratory Failure Related to GPA

2021 ◽  
Vol 8 ◽  
Author(s):  
Rongjun Wan ◽  
Wenzhe Yang ◽  
Xinhua Ma ◽  
Wei Yang ◽  
Pinhua Pan ◽  
...  
Keyword(s):  
Respiratory Failure ◽  
Acute Respiratory Failure ◽  
Granulomatosis With Polyangiitis ◽  
Clinical Symptoms ◽  
Clinical Manifestations ◽  
Systemic Involvement ◽  
Online Databases ◽  
Appropriate Treatment ◽  
Wide Range ◽  
Life Threatening

Granulomatosis with polyangiitis (GPA) is a subtype of anti-neutrophil cytoplasmic antibody-associated vasculitis with a wide range of clinical symptoms related to the systemic involvement of small blood vessels. The respiratory system is one of the most frequently involved, and life-threatening acute respiratory failure could occur due to diffusive alveolar hemorrhage and tracheal stenosis. When maximum mechanical ventilation is unable to maintain oxygenation, extracorporeal membrane oxygenation (ECMO) should be considered as the final respiratory supportive method, if available. Here we present a 32-year-old male patient with acute respiratory failure (ARF) related to GPA, who was rescued by winning time for accurate diagnosis and appropriate treatment. Additionally, we reviewed more than 60 GPA-related ARF cases on multiple online databases, summarized the clinical manifestations of these patients, and concluded that ECMO plays an important role in further respiratory support for ARF patients with GPA and assists in accurate and timely diagnosis and appropriate treatment, thus helping them recuperate.

scholarly journals Kinetics of SARS-CoV-2 antibody responses pre- and post- COVID-19 convalescent plasma transfusion in patients with severe respiratory failure: an observational case-control study

2020 ◽  
Author(s):  
Matthew N. Klein ◽  
Elizabeth Wenqian Wang ◽  
Paul Zimand ◽  
Heather Beauchamp ◽  
Caitlin Donis ◽  
...  
Keyword(s):  
Respiratory Failure ◽  
Ecmo Support ◽  
Control Group ◽  
Severe Respiratory Failure ◽  
Before And After ◽  
Life Threatening ◽  
Antibody Titers ◽  
Similar Survival ◽  
Kinetics Of ◽  
Control Study

ABSTRACTOBJECTIVESTo investigate if COVID-19 convalescent plasma (CCP) transfusion in patients with severe respiratory failure will increase plasma levels of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) antibody titers while improving survival and clinical outcomes.DESIGNObservational, retrospective, control study of anti-Receptor binding domain (RBD) of SARS-CoV-2 IgG and IgM titers from serial plasma samples drawn before and after CCP administration. Clinical improvement in CCP recipients is assessed and compared to COVID-19 control patients.SETTINGPatients hospitalized with severe COVID19, United States, between April 17 and July 19, 2020PARTICIPANTS34 patients hospitalized with severe or life threatening COVID-19 and who consented and received a CCP transfusion, 95 control patients with COVID-19 not transfused with CCP. 34 out the 95 control patients were matched for age, sex, and the level of respiratory support required. Patients less than 18 years old were excluded.MAIN OUTCOME MEASURESSerial trends of anti-RBD of SARS-CoV-2 IgG and IgM titers in CCP recipients are compared to those in control patients. The primary outcome is survival at 30 days, and the secondary outcomes are length of ventilatory and/or extracorporeal membrane oxygenation (ECMO) support, length of stay (LOS) in the hospital, and LOS in the ICU.RESULTSCCP transfusion occurred in 34 patients at a median of 12 days following COVID-19 symptom onset. Immediately prior to CCP transfusion, patients median anti-RBD SARS-CoV-2 IgG and IgM titers were 1:3200 (IQR, 1:50 to 1:9600) and 1:320 (IQR, 1:40 to 1:640) respectively. Following a Loess regression analysis, the kinetics and distribution of anti-RBD of SARS-CoV-2 IgG and IgM in plasma from CCP recipients were comparable to those from a control group of 68 patients who did not receive CCP. CCP recipients presented with similar survival, similar duration on ventilatory and/or ECMO support, as well as ICU and hospital LOS, compared to a matched control group of 34 patients.CONCLUSIONIn the present study, hospitalized COVID-19 patients with severe respiratory failure transfused with CCP presented with high titers of SARS-CoV-2 IgG antibodies before transfusion and did not show improved survival at 30 days.

scholarly journals Medical High Dependency Unit series, Article 3: Respiratory Support in the MHDU

2017 ◽  
Vol 16 (3) ◽  
pp. 115-122
Author(s):  
Christopher John Wright ◽  
◽  
Russell Morton Allan ◽  
Stuart A Gillon ◽  
◽  
...  
Keyword(s):  
Respiratory Failure ◽  
Acute Respiratory Failure ◽  
Key Management ◽  
Respiratory Support ◽  
Severe Respiratory Failure ◽  
High Dependency Unit ◽  
Non Invasive ◽  
High Dependency ◽  
Threatening Condition ◽  
Life Threatening

Acute respiratory failure is a life threatening condition encountered by Acute Physicians; additional non-invasive support can be provided within the medical high dependency unit (MHDU). Acute Physicians should strive to be experts in the investigation, management and support of patients with acute severe respiratory failure. This article outlines key management principles in these areas and explores common pitfalls.

scholarly journals Acute respiratory failure following ovarian hyperstimulation syndrome

2013 ◽  
pp. 43-47 ◽  
Author(s):  
Antonello Nicolini ◽  
Alessandro Perazzo ◽  
Piergiorgio Gatto ◽  
Mario Santo ◽  
Monica Bonfiglio
Keyword(s):  
Intensive Care ◽  
Respiratory Failure ◽  
Pleural Effusion ◽  
Ovarian Hyperstimulation Syndrome ◽  
Ovarian Hyperstimulation ◽  
Severe Respiratory Failure ◽  
Invasive Ventilation ◽  
Non Invasive ◽  
Non Invasive Ventilation ◽  
Life Threatening

Ovarian hyperstimulation syndrome is a serious and potentially life-threatening physiological complication that may be encountered in patients who undergo controlled ovarian hyperstimulation cycles. The syndrome is typically associated with regimes of exogenous gonadotropins, but it can be seen, albeit rarely, when clomiphene is administered during the induction phase. Although this syndrome is widely described in scientific literature and is well known by obstetricians, the knowledge of this pathological and potentially life-threatening condition is generally less than satisfactory among physicians. The dramatic increase in therapeutic strategies to treat infertility has pushed this condition into the realm of acute care therapy. The potential complications of this syndrome, including pulmonary involvement, should be considered and identified so as to allow a more appropriate diagnosis and management. We describe a case of a woman with an extremely severe (Stage 6) ovarian hyperstimulation syndrome who presented ascites, bilateral pleural effusion and severe respiratory failure treated with non-invasive ventilation. The patient was admitted to the intensive care unit because of severe respiratory failure, ascites, and bilateral pleural effusion due to ovarian hyperstimulation syndrome. Treatment included non-invasive ventilation and three thoracentesis procedures, plus the administration of albumin, colloid solutions and high-dose furosemid. Severe form of ovarian hyperstimulation syndrome is observed in 0.5-5% of the women treated, and intensive care may be required for management of thromboembolic complications, renal failure and severe respiratory failure. Pulmonary intensive care may involve thoracentesis, oxygen supplementation and, in more severe cases, assisted ventilation. To our knowledge, there have been only two studies in English language medical literature that describe severe respiratory failure treated with non-invasive ventilation.

scholarly journals Catamenial Hemoptysis and Pneumothoraces in a Patient with Cystic Fibrosis

2007 ◽  
Vol 14 (5) ◽  
pp. 295-297 ◽  
Author(s):  
Chris M Parker ◽  
Robert Nolan ◽  
M Diane Lougheed
Keyword(s):  
Magnetic Resonance Imaging ◽  
Computed Tomography ◽  
Cystic Fibrosis ◽  
Oral Contraceptive ◽  
Resonance Imaging ◽  
Present Patient ◽  
Thoracic Computed Tomography ◽  
Life Threatening ◽  
Catamenial Hemoptysis ◽  
Thoracic Endometriosis

Hemoptysis or pneumothorax that recurs with the onset of menses is strongly suggestive of thoracic endometriosis syndrome (TES). TES is a rare disorder, with relatively few cases reported in the literature. A 32-year-old woman with cystic fibrosis, who over a period of several months had experienced recurrent catamenial hemoptysis and pneumothoraces, including an episode of life-threatening hemoptysis that coincided with menstruation, is presented. Thoracic computed tomography and magnetic resonance imaging scans, as well as a bronchosopic evaluation that demonstrated endobronchial lesions that disappeared after menses, support the diagnosis of TES in the present patient. The patient was treated empirically with danazol and subsequently underwent a successful double-lung transplantation. Danazol was discontinued postoperatively, and she was started on an oral contraceptive. Eighteen months post-transplant, she has not experienced a recurrence of her catamenial symptoms, despite having resumed a regular menstrual cycle.

Esophageal atresia and severe respiratory failure—cuffed pediatric tracheal tubes as an additional therapeutic option?

2005 ◽  
Vol 40 (6) ◽  
pp. e25-e27 ◽  
Author(s):  
Michael Ehlen ◽  
Haitham Bachour ◽  
Beatrix Wiebe ◽  
Peter Bartmann ◽  
Heiko Birkhold
Keyword(s):  
Respiratory Failure ◽  
Esophageal Atresia ◽  
Therapeutic Option ◽  
Severe Respiratory Failure

scholarly journals Severe Spontaneous Pneumomediastinum in a Girl with Cystic Fibrosis

2021 ◽  
Vol 09 (01) ◽  
pp. e65-e67
Author(s):  
Csaba Zsiborás ◽  
Mária Adonyi ◽  
József Stankovics ◽  
András Farkas ◽  
Peter Vajda ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Cystic Fibrosis ◽  
Respiratory Failure ◽  
Respiratory Distress ◽  
Surgical Intervention ◽  
Severe Respiratory Failure ◽  
Thoracic Pain ◽  
Chest Computed Tomography ◽  
Spontaneous Pneumomediastinum ◽  
Rare Situation

AbstractWe report on an 11-year-old girl with cystic fibrosis who presented with thoracic pain and an extensive subcutaneous emphysema and subsequently developed progressive respiratory distress. The chest computed tomography revealed a huge pneumomediastinum. Due to the development of severe respiratory failure, urgent needle thoracocentesis was necessary that resulted in only temporary improvement. Therefore, under general anesthesia two mediastinal drains were introduced. Using active suction, the size of the pneumomediastinum decreased gradually and the drains were removed after 3 weeks. Here, we describe an extremely rare situation, when acute surgical intervention was necessary in a child with spontaneous pneumomediastinum.

Sign in / Sign up

Export Citation Format

Share Document