Amoxycillin Injection in the Treatment of Pyogenic Meningitis in Children

1979 ◽  
Vol 7 (2) ◽  
pp. 127-131
Author(s):  
M J Maguire ◽  
A A Khan

An open trial of the use of amoxycillin injection in the treatment of pyogenic meningitis in children showed similar results to previous trials here of penicillin-chloramphenicol combinations. It is felt that, in developing countries at least, treatment of pyogenic meningitis in children should be with the latter combination, but where rapid and accurate bacteriology is available amoxycillin may be a valuable non-toxic alternative to chloramphenicol with similar activity to ampicillin.

2018 ◽  
Vol 28 (1) ◽  
pp. 6-11
Author(s):  
MB Uddin ◽  
M Rahman ◽  
KI Jahan ◽  
S Yeasmin ◽  
F Rahman

Meningitis is an emergency clinical problem in pediatrics. The mortality from meningitis is close to 100% in untreated individuals and can still be up to 40% in children who received appropriate antibiotic therapy in developing countries. A cross sectional study was done to address the common presentation of meningitis among the children. The study was conducted in the Pediatric unit of Rajshahi Medical College Hospital from March 2008 to July 2009. A total of 130 suspected case of meningitis patients were included in the study. Among them 102 were diagnosed as meningitis of 66 children with pyogenic meningitis, 36 children with aseptic meningitis and 28 children without meningitis were taken as non meningitis group. This study showed that all patients (100%) had fever. 97 (95.10%) had symptom of convulsion. Vomiting was present in 62 (60.78%), excessive cry or irritability present in 50(49%) cases. This study expressed that 75 (73.53%) patients had bulged fontanel. Neck rigidity was present in 67 (65.69%). Only 32.35% had kernig’s sign positive and 17.65% present with Brudginsky’s sign positive. The infancy was the most vulnerable age for pyogenic meningitis. H. influenzae were the leading pathogen (24.24%) in infancy followed by S. pneumoniae (21.21%). The result shows that among 66 pyogenic meningitis, 26 (39.39%) were completely cured and 24 (36.37%) were cured with sequelae. Out of 36 aseptic meningitis 27 (75.00%) were completely cure.TAJ 2015; 28(1): 6-11


1968 ◽  
Vol 35 (9) ◽  
pp. 423-428 ◽  
Author(s):  
J. R. Srivastava ◽  
V. K. Srivastava ◽  
S. N. Mehrotra ◽  
K. C. Samuel

2009 ◽  
Vol 49 (3) ◽  
pp. 169
Author(s):  
Thermiany Anggri Sundari ◽  
Soetjiningsih Soetjiningsih ◽  
Sri Supar Yati Soenarto ◽  
I P. G. Karyana

Background The composition of the WHO's standard oral rehydration solution (ORS) is similar to that of choleric stool. Currently, there are questions about whether the composition is acceptable for treating dehydration caused by diarrhea. Efforts are being made to try and improve the WHO ORS, e.g., to decrease the solution osmolarity to avoid hypertonic side effects.lt is acknowledged that if glucose is used in ORS, the sodium will go through enterocytes and glucose will tum into an absolute substance for the formula. Glucose is less affordable and not widely produced in developing countries, hence researchers are currently exploring substitutes such as rice flour.Objective To compare the efficacy of reduced osmolarity ORS,rice-based ORS and the WHO standard ORS among childrenwith acute diarrhea.Methods A randomized open trial was conducted in children aged6-59 months old admitted for acute diarrhea. One-way AN OVAwas used to compare the three different types of ORS given.Results The mean duration of diarrhea was significantly lower inthe group treated with reduced osmolarity ORS (52.66 h, 95%CI 4 7.13 to 58.18) and rice-based ORS (54.66 h, 95% CI 4 7.97to 61.34) compared to the group treated with the WHO standardORS (67.34 h, 95% CI 61.50 to 73.18). Multivariate analysisshows that intervention had a significant effect on reducing theduration of diarrhea.Conclusions Reduced osmolarity ORS and rice-based ORSsignificantly lower the mean duration of children with acutediarrhea compared with the group treated with the WHO standardORS.


2015 ◽  
Vol 45 (2) ◽  
pp. 166
Author(s):  
Aditya Arifianto ◽  
Lina Lasminingrum ◽  
Nurakbar Aroeman ◽  
Shinta Fitri Boesoirie

Latar belakang: Displasia Mondini  adalah kasus yang jarang ditemukan namun merupakan penyebab penting terjadinya meningitis berulang pada anak dan membutuhkan indeks kecurigaan klinisyang tinggi sehingga dapat dilakukan diagnosis sedini mungkin. Displasia Mondini  adalah kelainankongenital berupa malformasi koklea yang terjadi akibat dari gangguan perkembangan embrio pada telingabagian dalam, di minggu ke tujuh. Anomali kongenital tulang temporal dapat menyebabkan  fistulisasiantara telinga tengah dan ruang subarakhnoid. Tujuan: Mempresentasikan kasus displasia Mondini dengan komplikasi meningitis berulang. Kasus: Satu kasus displasia Mondini  disertai hipertrofi adenoiddan meningitis berulang pada anak laki-laki usia enam tahun. Penatalaksanaan: Medikamentosa denganpemberian antibiotik dan adenoidektomi. Kesimpulan: Displasia Mondini  dengan faktor predisposisihipertrofi adenoid disertai meningitis berulang yang dilakukan adenoidektomi memberikan hasil yangbaik dengan tidak didapatkan kembali meningitis berulang pada pasien setelah tiga tahun. Kata kunci : displasia Mondini, hipertrofi adenoid, adenoidektomi, meningitis berulang  ABSTRACTBackground: Mondini dysplasia is a rare case but has an important role for recurrent pyogenic meningitis in children and requires a high index of clinical suspicion for early diagnosis. Mondinidysplasia is malformation of the cochlea due to impairment of the embryonic development of the innerear during the seventh week of fetal life. Congenital anomalies of temporal bone may cause fistulisation between the middle ear and subarachnoid space. Purpose: To present a case of Mondini dysplasia with recurrent meningitis complication. Case: A  case of Mondini dysplasia accompanied by hypertrophyadenoid and recurrent meningitis in a six year old boy. Management: Medical treatment with antibioticand adenoidectomy. Conclusion: Adenoidectomy for management of Mondini dysplasia with recurrentmeningitis accompanied by adenoid hypertrophy, gave a good result with no recurrent meningitis afterthree years. Key words: Mondini dysplasia, adenoid hypertrophy, adenoidectomy, recurrent meningitis


2000 ◽  
Vol 58 (3B) ◽  
pp. 843-851 ◽  
Author(s):  
MARCELO MASRUHA RODRIGUES ◽  
SANDRA JAGER PATROCÍNIO ◽  
MURILO GIMENES RODRIGUES

In spite of the steady increase in the incidence of Staphylococcus aureus infections, it remains a relatively uncommon cause of meningitis. To our knowledge, no series of community-acquired S. aureus meningitis (CASAM) restricted to children has been published. So far in this retrospective study we report our experience with CASAM in children, hospitalized from 1983 to 1998 at Nossa Senhora da Glória Children's Hospital (HINSG). During the sixteen-year study period, 2,319 new cases of acute pyogenic meningitis were diagnosed at HINSG. Community-acquired S. aureus was identified as the causative agent in 30 patients (1.3 percent). The predominantly spinal localization of the agent is stressed. In contrast with publications which analyze adults, it has a better prognosis.


2003 ◽  
Vol 23 (4) ◽  
pp. 233-253 ◽  
Author(s):  
David G. Fuller ◽  
Trevor Duke ◽  
Frank Shann ◽  
Nigel Curtis

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