Epithelioid Sarcoma-like Hemangioendothelioma a Case Report

2005 ◽  
Vol 91 (5) ◽  
pp. 436-439 ◽  
Author(s):  
Cigdem Tokyol ◽  
Nüket Uzüm ◽  
Ilhami Kuru ◽  
Omer Uluoglu

Seven cases of an unusual low-grade vascular tumor were reported in a recent study. Despite its similarity to epithelioid sarcoma, this tumor was termed epithelioid sarcoma-like hemangioendothelioma because of the subtle histopathological and immunohistochemical differences. Another case of this rare entity in a 70-year-old woman who suffered from a painful mass on the anterior aspect of the right cubital fossa is presented here, together with a review of the relevant literature.

2001 ◽  
Vol 15 (4) ◽  
pp. 267-270 ◽  
Author(s):  
Rie Yasui ◽  
Toru Minatogawa ◽  
Naoyuki Kanoh ◽  
Yasuo Nakata ◽  
Akira Kubota

Nasal hemangiopericytoma-like (HPCL) tumor is a rare vascular tumor and should be differentiated from typical hemangiopericytomas (HPCs). This study reports the case of an HPCL tumor in a 77-year-old man with histological and immunohistochemical features. After preoperative evaluation of the blood supply, the dark-red right intranasal tumor was resected completely via the right maxillary sinus. The final histopathological diagnosis was HPCL tumor based on several stains: vimentin (+), α-SMA (+), etc. Moreover, there were few p53 (+) cells and the Ki-67 and topoisomerase IIα labeling indices were both under 5%. These findings indicated that this tumor was a low-grade malignancy. The immunohistochemical investigations used are useful for making the diagnosis of HPCL tumor and determining the treatment, malignancy, and prognosis. (American Journal of Rhinology 15 267–270, 2001)


2019 ◽  
Vol 10 ◽  
pp. 215265671988903 ◽  
Author(s):  
Madison J. Malfitano ◽  
Meghan N. Norris ◽  
Wesley H. Stepp ◽  
Griffin D. Santarelli ◽  
T. Danielle Samulski ◽  
...  

Background Hyalinizing clear cell carcinomas (HCCCs) are rare, low-grade, malignant tumors which most often arise from the minor salivary glands primarily in palate and tongue but can arise in any location with minor salivary glands including the nasopharynx. Methods A case report of primary nasopharyngeal HCCC is presented. Because of the rarity of this tumor and location, a literature search was conducted to determine the most common presenting symptoms, treatment strategies, and outcomes. Results A 48-year-old man underwent biopsy of a 4.5 cm mass of the right nasopharynx with pathology suggesting an intermediate grade mucoepidermoid carcinoma. After discussing management with the patient, an endoscopic resection was performed. Final pathology revealed an HCCC which was confirmed after negative Mastermind-like 2 (MAML2) and positive Ewing sarcoma breakpoint region 1 (ESWR1) gene rearrangements on fluorescence in situ hybridization (FISH) studies. Literature review of other nasopharyngeal HCCC cases shows diverse presentation and overall excellent prognosis through surgical and radiation therapy. Conclusion HCCCs are rare, low-grade malignant tumors of the minor salivary glands and can present as a nasopharyngeal mass. Presenting symptoms are diverse but frequently involve otologic and sinonasal disturbances. HCCC is an indolent tumor with an excellent prognostic outcome when treated appropriately with surgical resection and adjuvant radiotherapy.


2020 ◽  
Vol 2020 (8) ◽  
Author(s):  
Amjad Soltany ◽  
Ghazal Asaad ◽  
Rami Daher ◽  
Mouhannad Dayoub ◽  
Ali Khalil ◽  
...  

Abstract Ameloblastic fibrosarcoma (AFS) is a rare, aggressive malignant odontogenic tumor. AFS is seen most frequently in second and third decades of life. We are reporting a case of a low grade AFS in a 21-year-old male complaining of a painless swelling in the right side of the maxilla. The patient was treated with surgical excision followed by radiotherapy, which is considered the most effective approach for most of soft tissue sarcomas. AFS has a high-reported recurrence rate (up to 37%); therefore, long-term surveillance for recurrence is crucial.


2015 ◽  
Vol 7 (1) ◽  
pp. 18-25 ◽  
Author(s):  
Phil Milburn-McNulty ◽  
Andrew J. Larner

We report a patient presenting with episodes of transient amnesia, some with features suggestive of transient global amnesia (TGA), and some more reminiscent of transient epileptic amnesia. Investigation with neuroimaging revealed an intrinsic lesion in the right amygdala, with features suggestive of low-grade neoplasia. We undertook a systematic review of the literature on TGA and brain tumour. Fewer than 20 cases were identified, some of which did not conform to the clinical diagnostic criteria for TGA. Hence, the concurrence of brain tumour and TGA is very rare and of doubtful aetiological relevance. In some brain tumour-associated cases, epilepsy may be masquerading as TGA.


2008 ◽  
Vol 12 (4) ◽  
pp. 180-183 ◽  
Author(s):  
Mike S. Kalisiak ◽  
Richard M. Haber

Background: Angioma serpiginosum is a vascular anomaly that classically presents in childhood and predominantly affects females. Objective: To present a case of a young woman with linear distribution of angioma serpiginosum and review the common clinical characteristics and presentation of this condition. Methods: Case report with skin biopsies and dermoscopic findings. Results: A clinical examination revealed numerous irregular punctate red macules in a linear distribution over the right arm. On dermoscopy, the lesions appeared as multiple sharply demarcated red lagoons. The histopathologic findings of dilated blood vessels in the papillary dermis with absence of other changes confirmed the diagnosis of angioma serpiginosum. Conclusion: Angioma serpiginosum is a rare entity that can be distinguished by clinical and histopathologic examinations. Lack of recognition of this condition may lead to unnecessary investigations and delayed treatment.


2020 ◽  
Vol 8 (10) ◽  
pp. 1263-1267
Author(s):  
Abdulrahman M. Bin Mohi ◽  
◽  
Ahmed A. Alzahrani ◽  
Bashar R. Reda

Chondromais considered a nonmalignant tumor that composed of mature hyaline cartilage and commonly occur in hands and feet. Overall incidents show that females are predominant comparing to males with evenly distributed range of ages. Multiple chondromas have to be differentiated from osteochondroma and chondrosarcoma. This paper reports three different types of lesions in one patient.Osteochondroma or exostosis is the most common benign tumor of the skeleton. It is a developmental osseous anomaly, which arises from exophytic outgrowth on bone surfaces characteristically. Osteochondroma account for about 12% of bone tumors. Here, we have described a 22 years old female patient with left knee joint pain and swelling of the left distal femur with limited movements. The incisional biopsy of the left distal femur identified low-grade chondrosarcoma and chondroma after histopathology. This underwent one-stage surgical excision of the tumor with a posterior approach and tumor resection from the femur. After surgery, an unusual pain appears in the right hip joint during the post-operative period.Machine resonance imaging (MRI), and X-ray of pelvis help to diagnose thewell-differentiated chondrosarcoma and chondroma. This was a case of osteochondroma in the right proximal femur, chondroma like lesion in the left proximal femur and chondrosarcoma in the left distal femur. Ethical consideration: Written informed consent was obtained from the patient for publication of this case report and accompanying images. Conflict of interest: There is no conflict of interest.


2019 ◽  
Vol 6 (7) ◽  
pp. C75-79
Author(s):  
Kumarguru B. N. Kumarguru B. N. ◽  
◽  
Navya N Navya N ◽  
Prashanth R Prashanth R ◽  
Arathi C. A. Arathi C. A. ◽  
...  

2019 ◽  
Vol 15 (04) ◽  
pp. 206-211
Author(s):  
José Alberto Carranco Dueñas ◽  
Genny Sánchez Hernández ◽  
Rosa Edith Gálvez Martínez

Abstract Salmonella osteomyelitis is a rare entity, typically associated with hemoglobinopathies or other underlying disorders. We report a case of Salmonella osteomyelitis of the right knee in an otherwise healthy 1-year-old boy. He received 8 weeks (2 weeks intravenous and 6 weeks oral) of antibiotic treatment, with full recovery.


1970 ◽  
Vol 5 (2) ◽  
pp. 139-147
Author(s):  
Paula Boson Trotta ◽  
Karen Guimarães Rosa ◽  
Luciano Martins Alves da Rosa Martins Alves da Rosa

RESUMOIntrodução: O Sarcoma Fibroblástico Mixoinflamatório (SFMI) é um tumor de partes moles de baixo grau, raro, que apresenta predileção equivalente em ambos os gêneros, sem sofrer influência de fatores genéticos ou ambientais. Apresenta sintomas inespecíficos, o que dificulta o diagnóstico. A dor está presente no diagnóstico em cerca de 17% dos pacientes. Outro fator que atrapalha o diagnóstico está na raridade do tumor e inabilidade técnica de detectá-lo. Casuística: Apresenta-se um caso de um paciente do sexo masculino, de 47 anos encaminhado ao ortopedista com tumoração em região distal do segundo quirodáctilo da mão direita. Após cirurgia de ressecção tumoral foi detectado um tecido que se originava na falange distal e tinha coloração amarelada e consistência densa, mesclado com o subcutâneo. Observou-se isquemia transitória na polpa digital da falange distal ainda durante a cirurgia. Posterior exame imuno-histoquímico revelou tratar-se de um Sarcoma Fibroblástico Mixoinflamatório. Após a cirurgia, o paciente retorna com necrose da polpa digital submetida a cirurgia. Foi realizada limpeza e debridamento do tecido necrótico. O paciente evoluiu bem com total epitelização da área cruenta. Conclusão: Foi concluído tratar-se de um sarcoma de difícil diagnóstico, porém de baixa metastatização e bom prognostico.Palavras-chave: Sarcoma, Isquemia, Necrose. ABSTRACTIntroduction: Myxoinflammatory Fibroblastic Sarcoma is a low-grade, rare tumor of soft parts that presents equivalent predilection for both genders  suffering no influence of genetic or enviormental factors. It has non-specific symptoms, making it difficult to diagnose. Pain appears in the diagnosis only in 17% of patients. Another factor that hinders the diagnosis is in the fewness numbers of patients that have it, and the technical inability to detect it. Case Report: This case report describes the case of a male patient, 47 years old, that referred to the orthopedist a tumor in the distal region of the second finger of the right hand. After tumor resection it was detected a tissue that originated in the distal phalanx and had a yellowish color and dense consistency, mixed with the subcutaneous tissue. It was observed transient ischemia in the digital pulp of the distal phalanx during surgery. Subsequent immunohistochemical examination revealed that it was Myxoinflammatory Fibroblastic Sarcoma. After the surgery, the patient returned with necrosis of the fingertip. Cleaning and debridement of necrotic tissue was performed. The patient developed a complete epithelialization of the wound area. Conclusion: The conclusion is that this is a sarcoma which is difficult to diagnose, but with low metastasis and good prognosis.Keywords: Sarcoma, Ischemia, Necrosis.


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