End Results of Surgical Treatment of 622 Cases of Tumors of the Salivary Glands.

1974 ◽  
Vol 60 (4) ◽  
pp. 307-316 ◽  
Author(s):  
Carmelo Vinicio Catania ◽  
Emanuele Galante ◽  
Gaetano Bandieramonte ◽  
Bruno Salvadori
Keyword(s):  
Salivary Glands ◽  
Radical Surgery ◽  
Malignant Tumors ◽  
Survival Rates ◽  
High Rate ◽  
Surgical Removal ◽  
Minor Salivary Glands ◽  
Benign Lesions ◽  
Submandibular Glands ◽  
Mixed Tumors

Surgery was performed on 622 patients with tumors of the salivary glands from 1929 to 1972; the gland affected was the parotid in 527 cases, the submandibular glands in 50, and minor salivary glands of palate and other sites in 45. The analysis of distant results point out that both for benign and malignant tumors total sialoadenectomy must be the treatment of choice, as demonstrated by the high rate of recurrence after local excision or partial resection of the gland, even in cases of surely benign lesions such as mixed tumors. It is worthy of being quoted the high rate of recurrence from cylindromas, especially of the palate (48.5%), after surgical removal. As to malignancies of parotid and submandibular glands 5-years survival rates after radical surgery were of 52 % and 30 % respectively.

Primary intracranial germ cell tumors: a clinical analysis of 153 histologically verified cases

1997 ◽  
Vol 86 (3) ◽  
pp. 446-455 ◽  
Author(s):  
Masao Matsutani ◽  
Keiji Sano ◽  
Kintomo Takakura ◽  
Takamitsu Fujimaki ◽  
Osamu Nakamura ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Germ Cell ◽  
Malignant Tumors ◽  
Survival Rates ◽  
Germ Cell Tumors ◽  
Surgical Removal ◽  
Content Type ◽  
Intracranial Germ Cell Tumors ◽  
Mixed Tumors ◽  
Fine Print

✓ The authors analyzed 153 cases of histologically verified intracranial germ cell tumors. The histological diagnosis was germinoma in 63 patients (41.2%), teratoma in 30 (19.6%), and other types of tumors in 60 patients (39.2%). The patients were treated by a consistent policy of surgical removal with histological verification followed by radiation therapy with or without chemotherapy. The 10- and 20-year survival rates of patients with pure germinoma were 92.7% and 80.6%, respectively. The 10-year survival rates of patients with mature teratoma and malignant teratoma were 92.9% and 70.7%, respectively. Patients with pure malignant germ cell tumors (embryonal carcinoma, yolk sac tumor, or choriocarcinoma) had a 3-year survival rate of 27.3%. The mixed tumors were divided into three subgroups: 1) mixed germinoma and teratoma; 2) mixed tumors whose predominant characteristics were germinoma or teratoma combined with some elements of pure malignant tumors; and 3) mixed tumors with predominantly pure malignant elements. The 3-year survival rates were 94.1% for the first group, 70% for the second group, and 9.3% for the third group, and the differences were statistically significant. Twenty-six patients with malignant tumors received chemotherapy that consisted of cisplatin and carboplatin combinations with or without radiation therapy. However, chemotherapy was not significantly more effective than radiation therapy alone. From these treatment results, the authors classified tumors into three groups with different prognoses and proposed a treatment guideline appropriate for the subgroups.

scholarly journals An unusual pleomorphic adenoma

2014 ◽  
Vol 62 (3) ◽  
pp. 319-324
Author(s):  
Christiano Sampaio QUEIROZ ◽  
Roberto Almeida de AZEVEDO ◽  
Antonio Irineu TRINDADE NETO ◽  
Caetano Guilherme Carvalho PONTES ◽  
Rafael de Queiroz MOURA
Keyword(s):  
Salivary Gland ◽  
Salivary Glands ◽  
Pleomorphic Adenoma ◽  
Histopathological Examination ◽  
Minor Salivary Gland ◽  
Surgical Excision ◽  
Biological Behavior ◽  
Surgical Removal ◽  
Minor Salivary Glands ◽  
Recommended Treatment

Pleomorphic adenoma is the most common neoplasm in major and minor salivary glands. It constitutes approximately 90% of all benign salivary gland lesions and the parotid is the most affected location. When the minor salivary glands are affected, it mostly occurs at the junction of the hard and soft palates. The diagnosis is complex because of the great histological variety and biological behavior of this tumor, a histopathological examination being essential. The recommended treatment is surgical excision. For lesions located superficially in the parotid gland, superficial parotidectomy - identifying and preserving the facial nerve - is necessary. Lesions in the palate or gums sometimes demand a margin of safety, being excised below the periosteum, including the overlying mucosa. With correct surgical removal, the prognosis is excellent. The aim of this study is to report a case of an unusual minor salivary gland pleomorphic adenoma in the hard palate, describing the most important aspects of this pathology.

scholarly journals Nasopharyngeal Hyalinizing Clear Cell Carcinoma: A Case Report and Review of the Literature

2019 ◽  
Vol 10 ◽  
pp. 215265671988903 ◽  
Author(s):  
Madison J. Malfitano ◽  
Meghan N. Norris ◽  
Wesley H. Stepp ◽  
Griffin D. Santarelli ◽  
T. Danielle Samulski ◽  
...  
Keyword(s):  
Case Report ◽  
Salivary Glands ◽  
Clear Cell ◽  
Malignant Tumors ◽  
Treatment Strategies ◽  
Low Grade ◽  
Minor Salivary Glands ◽  
Presenting Symptoms ◽  
Nasopharyngeal Mass ◽  
The Right

Background Hyalinizing clear cell carcinomas (HCCCs) are rare, low-grade, malignant tumors which most often arise from the minor salivary glands primarily in palate and tongue but can arise in any location with minor salivary glands including the nasopharynx. Methods A case report of primary nasopharyngeal HCCC is presented. Because of the rarity of this tumor and location, a literature search was conducted to determine the most common presenting symptoms, treatment strategies, and outcomes. Results A 48-year-old man underwent biopsy of a 4.5 cm mass of the right nasopharynx with pathology suggesting an intermediate grade mucoepidermoid carcinoma. After discussing management with the patient, an endoscopic resection was performed. Final pathology revealed an HCCC which was confirmed after negative Mastermind-like 2 (MAML2) and positive Ewing sarcoma breakpoint region 1 (ESWR1) gene rearrangements on fluorescence in situ hybridization (FISH) studies. Literature review of other nasopharyngeal HCCC cases shows diverse presentation and overall excellent prognosis through surgical and radiation therapy. Conclusion HCCCs are rare, low-grade malignant tumors of the minor salivary glands and can present as a nasopharyngeal mass. Presenting symptoms are diverse but frequently involve otologic and sinonasal disturbances. HCCC is an indolent tumor with an excellent prognostic outcome when treated appropriately with surgical resection and adjuvant radiotherapy.

Primary Neoplasms of the Salivary Glands in Animals Compared to Similar Tumors in Man

1965 ◽  
Vol 2 (3) ◽  
pp. 201-226 ◽  
Author(s):  
A. Koestner ◽  
L. Buerger
Keyword(s):  
Salivary Glands ◽  
Squamous Carcinoma ◽  
Mandibular Gland ◽  
Biological Behavior ◽  
Minor Salivary Glands ◽  
Morphological Pattern ◽  
Primary Neoplasms ◽  
Malignant Mixed Tumor ◽  
The Difference ◽  
Mixed Tumors

Thirty primary salivary tumors of animals (22 in dogs, 4 in horses, 2 in cats, 1 in a baboon and 1 in a guinea pig) were classified according to their histologic and biological characteristics and compared with their counterparts in man. According to criteria used in this report, 3 were classified as mucoepidermoid tumors (1 benign and 2 malignant), 1 as a squamous carcinoma, 5 as benign mixed tumors, 1 as a malignant mixed tumor, 12 as acinic cell tumors, 2 as ductular, 3 as trabecular, 2 as anaplastic adenocarcinomas and 1 as a malignant melanoma. The parotid gland was the site of the neoplasm in 16 cases, the mandibular gland in 5, the sublingual gland in 2 and minor salivary glands in the remaining 7. Except for the difference in proportional incidence of the various types of salivary neoplasms in animals as compared to man, they are similar in their morphological pattern and in their biological behavior.

Surgery for Malignant Tumors of the Minor Salivary Glands

2019 ◽  
pp. 97-122
Author(s):  
Davide Lombardi ◽  
Remo Accorona ◽  
Davide Lancini ◽  
Vittorio Rampinelli ◽  
Anna Bozzola ◽  
...  
Keyword(s):  
Salivary Glands ◽  
Malignant Tumors ◽  
Minor Salivary Glands

Bizarre Parosteal Osteochondromatous Proliferation of Bone (BPOP): an Unusual Foot Mass in a Child

2000 ◽  
Vol 21 (5) ◽  
pp. 404-407 ◽  
Author(s):  
Allison Gilmore ◽  
Joseph Khoury ◽  
Fadi W. Abdul Karim ◽  
R. Tracy Ballock
Keyword(s):  
Unusual Case ◽  
Malignant Tumors ◽  
High Rate ◽  
High Recurrence Rate ◽  
Low Grade ◽  
Benign Bone Tumor ◽  
Bizarre Parosteal Osteochondromatous Proliferation ◽  
Benign Lesions ◽  
Radiographic Appearance ◽  
Hands And Feet

This report describes an unusual case of bizarre parosteal osteochondromatous proliferation of bone (BPOP) which developed in the foot of an eight year-old child. Also described as Nora's lesion, BPOP is a rare benign bone tumor found most commonly in the hands and feet with a radiographic appearance occasionally confused with malignancy. Resembling osteochondromas at first glance, these lesions have a distinct radiographic and histologic appearance that permits differentiation from other benign lesions or low-grade malignant tumors. Treatment of BPOP consists of simple excision, although there is high rate of recurrence. Despite this high recurrence rate, there have been no reported metastases and local excision is still recommended.

scholarly journals Inflammatory pseudotumors after stem cell transplantation

2015 ◽  
Vol 7 (3) ◽  
Author(s):  
Asli Tufan ◽  
Gulistan Bahat
Keyword(s):  
Stem Cell ◽  
Stem Cell Transplantation ◽  
Cell Transplantation ◽  
Radical Surgery ◽  
Malignant Tumors ◽  
Distant Metastases ◽  
Benign Lesions ◽  
Hematopoietic Stem ◽  
Inflammatory Pseudotumors ◽  
Mass Lesions

Inflammatory pseudotumors (IPT) are rare tumors that occur in various organs and tissues. The clinical picture varies from the more frequent benign lesions to rare malignant tumors with distant metastases. IPTs associated with hematopoietic stem cell transplantation (HSCT) is rarely reported. In this article, we review the reports of IPT after HSCT. We also review the possible factors involved in the pathogenesis. IPT may be rare but they are a potentially serious complication of HSCT. A knowledge of these entities and insistence on a definitive biopsy of mass lesions in the post-HSCT period can avoid unnecessary treatment such as radical surgery, chemotherapy or radiotherapy.

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