Bioelectrical Impedance Analysis–Derived Measurements in Chronic Hepatitis C: Clinical Relevance of Fat-Free Mass and Phase Angle Evaluation

2017 ◽  
Vol 33 (2) ◽  
pp. 238-246 ◽  
Author(s):  
Tatiana Bering ◽  
Kiara G. D. Diniz ◽  
Marta Paula P. Coelho ◽  
Ana Carolina M. de Souza ◽  
Luisa Freitas de Melo ◽  
...  
2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Ana M. Araújo ◽  
Humberto S. Machado ◽  
Amílcar C. Falcão ◽  
Patrício Soares-da-Silva

Abstract Background Older people are currently the fastest growing segment of the worldwide population. The present study aimed to estimate propofol dose in older patients based on size descriptors measured by bioelectrical impedance analysis (BIA). Methods A cross sectional study in adult and older patients with body mass index equal to or lower than 35 kg/m2 was carried out. BIA and Clinical Frail Scale scoring were performed during pre-operative evaluation. Propofol infusion was started at 2000 mg/h until loss of consciousness (LOC) which was defined by “loss of eye-lash reflex” and “loss of response to name calling”. Total dose of propofol at LOC was recorded. Propofol plasma concentration was measured using gas chromatography/ion trap-mass spectrometry. Results Forty patients were enrolled in the study. Total propofol dose required to LOC was lower in Age ≥ 65 group and a higher plasma propofol concentration was measured in this group. 60% of old patients were classified as “apparently vulnerable” or “frail” and narrow phase angle values were associated with increasing vulnerability scores. In the Age ≥ 65 group, the correlation analysis showed that the relationship between propofol dose and total body weight (TBW) scaled by the corresponding phase angle value is stronger than the correlation between propofol dose and TBW or fat free mass (FFM). Conclusions This study demonstrates that weight-based reduction of propofol is suitable in older patients; however FFM was not seen to be more effective than TBW to predict the propofol induction dose in these patients. Guiding propofol induction dose according to baseline frailty score should also be considered to estimate individualized dosage profiles. Determination of phase angle value appears to be an easy and reliable tool to assess frailty in older patients. Trial registration ClinicalTrials.gov Identifier: NCT02713698. Registered on 23 February 2016.


Nutrients ◽  
2016 ◽  
Vol 8 (10) ◽  
pp. 654 ◽  
Author(s):  
Hsueh-Kuan Lu ◽  
Li-Ming Chiang ◽  
Yu-Yawn Chen ◽  
Chih-Lin Chuang ◽  
Kuen-Tsann Chen ◽  
...  

2020 ◽  
Vol 40 ◽  
pp. 201-207
Author(s):  
Linnea Bärebring ◽  
Ane Sørlie Kværner ◽  
Madeleine Skotnes ◽  
Hege Berg Henriksen ◽  
Anne Juul Skjetne ◽  
...  

2012 ◽  
Vol 109 (4) ◽  
pp. 639-647 ◽  
Author(s):  
Saijuddin Shaikh ◽  
Kerry J. Schulze ◽  
Anura Kurpad ◽  
Hasmot Ali ◽  
Abu Ahmed Shamim ◽  
...  

Equations for predicting body composition from bioelectrical impedance analysis (BIA) parameters are age-, sex- and population-specific. Currently there are no equations applicable to women of reproductive age in rural South Asia. Hence, we developed equations for estimating total body water (TBW), fat-free mass (FFM) and fat mass in rural Bangladeshi women using BIA, with 2H2O dilution as the criterion method. Women of reproductive age, participating in a community-based placebo-controlled trial of vitamin A or β-carotene supplementation, were enrolled at 19·7 (sd 9·3) weeks postpartum in a study to measure body composition by 2H2O dilution and impedance at 50 kHz using multi-frequency BIA (n 147), and resistance at 50 kHz using single-frequency BIA (n 82). TBW (kg) by 2H2O dilution was used to derive prediction equations for body composition from BIA measures. The prediction equation was applied to resistance measures obtained at 13 weeks postpartum in a larger population of postpartum women (n 1020). TBW, FFM and fat were 22·6 (sd 2·7), 30·9 (sd 3·7) and 10·2 (sd 3·8) kg by 2H2O dilution. Height2/impedance or height2/resistance and weight provided the best estimate of TBW, with adjusted R2 0·78 and 0·76, and with paired absolute differences in TBW of 0·02 (sd 1·33) and 0·00 (sd 1·28) kg, respectively, between BIA and 2H2O. In the larger sample, values for TBW, FFM and fat were 23·8, 32·5 and 10·3 kg, respectively. BIA can be an important tool for assessing body composition in women of reproductive age in rural South Asia where poor maternal nutrition is common.


2016 ◽  
Vol 27 (3) ◽  
pp. 665-669 ◽  
Author(s):  
Georgi Vassilev ◽  
Till Hasenberg ◽  
Johannes Krammer ◽  
Peter Kienle ◽  
Ulrich Ronellenfitsch ◽  
...  

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