The Roosevelt Hospital Banco de Leche: Nonprofit Human Donor Milk Bank in Guatemala City

2018 ◽  
Vol 35 (3) ◽  
pp. 563-568 ◽  
Author(s):  
Martha Jane Paynter ◽  
Ana Karen Celis-Hecht Mendoza
Keyword(s):  
Guatemala City ◽  
Human Donor ◽  
Donor Milk ◽  
Roosevelt Hospital ◽  
Milk Bank

Macronutrient content of donor milk from a regional human milk bank: variation with donor mother–infant characteristics

2019 ◽  
Vol 122 (10) ◽  
pp. 1155-1167 ◽  
Author(s):  
Luke Mills ◽  
Lynda Coulter ◽  
Emma Savage ◽  
Neena Modi
Keyword(s):  
Human Milk ◽  
Gestational Age ◽  
Fixed Effects ◽  
Energy Content ◽  
Human Donor ◽  
Donor Milk ◽  
Macronutrient Content ◽  
Lactation Stage ◽  
Milk Bank ◽  
Human Milk Bank

AbstractBetter understanding of the variation in macronutrient content of human donor milk (HDM) potentiates targeted nutrition for preterm babies. The present study describes the relationship of maternal age, parity, monthly lactation stage estimate (LSEm), daily volume of milk expressed (Vd), sex, gestation and birth weight z scores with macronutrient content of HDM. Multilevel mother–infant pair ID random intercept models were performed using the predictor variables above on the outcome HDM macronutrient content determined using mid-IR spectroscopy. Mean macronutrient content was also compared by gestational age and small for gestational age (SGA) (z score < –1·28) or appropriate for gestational age (AGA) (z score ≥ –1·28) categories. A total of 2966 samples of donations from 1175 mother–infant pairs to the UK Northwest Human Milk Bank between 2011 and 2017 were analysed. Mean protein, fat, carbohydrate and calculated energy were 0·89 (SD 0·24) g/dl, 2·99 (SD 0·96) g/dl, 7·09 (SD 0·44) g/dl, and 60·37 (SD 8·41) kcal/dl (252·59 (SD 35·19) kJ/dl), respectively. Preterm SGA HDM was significantly higher in protein, fat and energy content than term AGA HDM and significantly lower in carbohydrate content than term AGA HDM after controlling for LSEm, Vd and between-subject effects. Degree of prematurity did not influence macronutrient content. Between-subject effects accounted for more of the variance in macronutrient content than the fixed effects in the model. Despite this, SGA status, as well as prematurity, may be an important determinant of macronutrient content in human milk. As bioavailability of macronutrients from HDM is uncertain, studies evaluating growth and body composition in preterm and SGA babies fed HDM are warranted.

scholarly journals High Hydrostatic Pressure Processing Better Preserves the Nutrient and Bioactive Compound Composition of Human Donor Milk

2019 ◽  
Vol 149 (3) ◽  
pp. 497-504 ◽  
Author(s):  
Michael A Pitino ◽  
Sharon Unger ◽  
Alain Doyen ◽  
Yves Pouliot ◽  
Susanne Aufreiter ◽  
...  
Keyword(s):  
Hydrostatic Pressure ◽  
Vitamin C ◽  
Human Milk ◽  
High Hydrostatic Pressure ◽  
Very Low Birth Weight ◽  
Future Research ◽  
Low Birth Weight Infants ◽  
Human Donor ◽  
Donor Milk ◽  
Uv C

ABSTRACT Background When mother's milk is insufficient, pasteurized human donor milk (DM) is the recommended supplement for hospitalized very-low-birth-weight infants. The current method of pasteurization (Holder, 62.5°C, 30 min) negatively affects heat-sensitive nutrients and bioactive proteins. Objectives Objectives of this study were to compare changes in DM composition after thermal pasteurization (Holder and flash-heating) and nonthermal methods [UV-C irradiation and high hydrostatic pressure (HHP)]. We hypothesized that nonthermal techniques would result in fewer changes to composition. Methods Holder, flash-heating (brought to boil), UV-C irradiation (250 nm, 25 min), and HHP (500 MPa, 8 min) were studied. Pools of milk from 17 women known to contain bacteria at >5 × 107 colony forming units (CFU)/L were collected from the Rogers Hixon Ontario Human Milk Bank and underwent each pasteurization technique. Macronutrients, heat-sensitive micronutrients (vitamin C, folate), and bioactive components [bile-salt-stimulated lipase (BSSL), lysozyme, lactoferrin] were measured in raw and pools of pasteurized milk. Milk was cultured to determine how well each technique produced a culture negative result (detection limit <1 × 103 CFU/L). Results Folate was reduced by 24–27% after Holder, flash-heating, and UV-C (P < 0.05); no reduction was observed after HHP. All pasteurization methods reduced vitamin C (60–75%, P < 0.001). BSSL was abolished after Holder and flash-heating (P < 0.001), reduced after UV-C (48%, P < 0.001), but unaffected by HHP. Lysozyme activity was reduced after flash-heating (44%) and UV-C (74%, P < 0.004) but unaffected by Holder or HHP. Lactoferrin was reduced by all methods (P < 0.02) but most severely by flash-heating (74%) and least severely by HHP (25%). Holder and UV-C reduced lactoferrin by ∼48%. All pasteurization methods reduced the number of culture positive DM samples (P < 0.001). Conclusions HHP better preserves human milk composition than Holder pasteurization. Future research on the feasibility of HHP for pasteurizing human milk is warranted because its implementation may improve the nutritional status and health of DM-fed infants.

scholarly journals Short communication: Effect of refrigerated storage on the pH and bacterial content of pasteurized human donor milk

2018 ◽  
Vol 101 (12) ◽  
pp. 10714-10719 ◽  
Author(s):  
S. Vázquez-Román ◽  
D. Escuder-Vieco ◽  
M.D. Martín-Pelegrina ◽  
B. Muñoz-Amat ◽  
L. Fernández-Álvarez ◽  
...  
Keyword(s):  
Short Communication ◽  
Refrigerated Storage ◽  
Human Donor ◽  
Donor Milk ◽  
Bacterial Content ◽  
Communication Effect

scholarly journals The use of human donor milk

BMJ ◽  
2020 ◽  
pp. m4243
Author(s):  
Hoang Thi Tran ◽  
Tuan T Nguyen ◽  
Roger Mathisen
Keyword(s):  
Human Donor ◽  
Donor Milk

Differences in energy expenditure in human donor milk versus formula milk in preterm newborns: A crossover study

Nutrition ◽  
2019 ◽  
Vol 66 ◽  
pp. 1-4
Author(s):  
Fernanda Valente Mendes Soares ◽  
Andrea Dunshee Abranches ◽  
Maria Dalva Barbosa Baker Méio ◽  
Saint-Clair Gomes ◽  
Leticia Duarte Villela ◽  
...  
Keyword(s):  
Energy Expenditure ◽  
Crossover Study ◽  
Formula Milk ◽  
Human Donor ◽  
Donor Milk ◽  
Preterm Newborns

scholarly journals Human donor milk for the vulnerable infant: a Canadian perspective

2014 ◽  
Vol 9 (1) ◽  
pp. 4 ◽  
Author(s):  
Julia Panczuk ◽  
Sharon Unger ◽  
Deborah O’Connor ◽  
Shoo K Lee
Keyword(s):  
Human Donor ◽  
Donor Milk ◽  
Canadian Perspective

TO INVESTIGATE THE EFFECT OF THE PASTEURISATION PROCESS ON TRACE ELEMENTS IN DONOR BREAST MILK

2016 ◽  
Vol 101 (9) ◽  
pp. e2.20-e2 ◽  
Author(s):  
Nor Mohd Taufek ◽  
David Cartwright ◽  
Amitha Hewavitharana ◽  
Pieter Koorts ◽  
Helen McConachy ◽  
...  
Keyword(s):  
Trace Elements ◽  
Breast Milk ◽  
Inductively Coupled Plasma ◽  
Rank Correlation ◽  
Formula Milk ◽  
Donor Milk ◽  
Inductively Coupled ◽  
Spearman’S Rank Correlation ◽  
Milk Bank ◽  
Significant Difference

AimTo investigate the effect of the pasteurisation process on trace elements in donor breast milk.MethodPremature infants often receive donor breast milk when the mother is unable to produce sufficient breast milk. It is widely accepted that donor milk has considerable advantages over formula milk.1 The Royal Brisbane and Women's Hospital (RBWH) has a milk bank that receives milk donated by women which undergoes a pasteurisation process.2 This study investigated the effect of pasteurisation on a range of trace elements in donor milk.A total of 14 participants who donated to the milk bank were recruited in this study. A 2 ml sample was collected pre- and post- pasteurisation, and frozen at −80 °C. Post-natal age of the milk was documented. Inductively-coupled plasma mass-spectrometry was used to analyse the following trace elements – zinc (Zn), copper (Cu), selenium (Se), manganese (Mn), iodine (I), iron (Fe), molybdenum (Mo) and bromine (Br). The study received ethical approval from RBWH and The University of Queensland Ethics Committee.ResultsNo significant difference was found between the levels of any of the trace elements tested pre- and post-pasteurisation. The following p-values were calculated – Zn (0.82), Cu (0.80), Se (0.97), Mn (0.63), I (0.99), Fe (0.05), Mo (0.41), Br (0.59). The following ranges in mcg/L of trace elements were calculated – Zn (365.4–5460.0), Cu (157.6–820.5), Se (10.6–23.7), Mn (0.55–3.24), I (66.4–215.3), Fe (101.5–473.1), Mo (0.20–5.45), Br (704.9–3379.0). Spearman's rank correlation analysis showed significant correlations between post-natal age of milk and trace elements – Zn (ρ=−0.578), Se (ρ=−0.627). Fe (ρ=−0.704), and Mo (ρ=−0.534). No significant correlation was found for Cu, Mn, I, and Br.ConclusionThis study found that the pasteurisation process had minimal effect on trace element levels in donor breast milk. However, it was noted that there was a correlation between post-natal age of donor milk and Zn, Se, Fe and Mo. Further work is needed to establish factors that may influence levels of trace elements in donor milk such as post-natal age.

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