The role of circumcision, tobacco, and alcohol use in genital human papillomavirus infection among men from Denmark

2021 ◽  
pp. 095646242110147
Author(s):  
Julie B Hebnes ◽  
Christian Munk ◽  
Kirsten Frederiksen ◽  
Hans O Joergensen ◽  
Thomas Iftner ◽  
...  
Keyword(s):  
Risk Factors ◽  
Sexual Behavior ◽  
Human Papillomavirus ◽  
Alcohol Use ◽  
Potential Risk ◽  
Hpv Infection ◽  
Sex Partners ◽  
Current Cigarette Smoking ◽  
Hpv Dna ◽  
Potential Risk Factors

It is crucial to understand the natural history of genital human papillomavirus (HPV) infection in men to prevent the increasing male HPV-related disease burden. We evaluated the associations between HPV infection and circumcision, smoking, and alcohol use after accounting for sexual behavior. The study included 2331 male personnel from Danish barracks. Penile swabs were tested for HPV DNA with a polymerase chain reaction assay, INNO-LiPA. All men completed a self-administered questionnaire providing data on potential risk factors for HPV such as lifestyle and sexual habits. Using multivariable logistic regression, associations between potential risk factors and HPV infection were estimated and expressed as odds ratios (ORs) with 95% confidence intervals (CI). Current cigarette smoking was associated with increased odds of HPV detection (OR = 1.2; 95% CI: 1.0–1.4), but we found no association with alcohol use in the analysis adjusted for sexual behavior. Circumcision reduced the odds of a prevalent HPV infection (OR = 0.7; 95% CI: 0.5–1.0) although not statistically significantly. Strong associations with lifetime and recent number of female sex partners were observed, but in contrast to uncircumcised men, increasing number of sex partners was not associated with higher HPV prevalence in circumcised men. In conclusion, smoking was associated with increased odds of penile HPV in men from the general population in Denmark, whereas circumcision seemed to reduce the risk. Moreover, our results indicated that there might be differences in the viral susceptibility between circumcised and uncircumcised men.

Prevalence and risk factors of anogenital human papillomavirus infection in a community sample of men who have sex with men in Taiwan: baseline findings from a cohort study

2019 ◽  
Vol 96 (1) ◽  
pp. 62-66
Author(s):  
Carol Strong ◽  
Huachun Zou ◽  
Nai-Ying Ko ◽  
Ya-Lun Liang ◽  
Wen-Wei Ku ◽  
...  
Keyword(s):  
Risk Factors ◽  
Human Papillomavirus ◽  
Cost Effectiveness ◽  
Community Sample ◽  
Hpv Vaccination ◽  
Hpv Infection ◽  
Sex Partners ◽  
Anal Sex ◽  
The Past ◽  
Sex With Men

ObjectivesMen who have sex with men (MSM) are a highly neglected population in the current recommendation of girls-only human papillomavirus (HPV) vaccination programmes in many countries. To better assess the cost effectiveness of HPV vaccination among men requires data on the prevalence of HPV infection in MSM using a community sample, which is still sparse in several regions. We examined the prevalence of and factors associated with anogenital HPV infection among MSM in Taiwan.MethodsMSM 20 years of age and older were recruited from the community and social media in Taiwan in 2015–2016 and screened for HPV infection to detect 37 genotypes. MSM were seen at baseline and were/will be seen at 6, 12, 24 and 36 months. Men completed a questionnaire regarding their sexual experiences. Multivariable regression analyses were conducted to identify associated behavioural risk factors using the baseline data.ResultsA total of 253 MSM were recruited; 87 % were below 35 years of age. Diagnosis of HIV was reported in 4% of men; just over 20% had three or more anal sex partners in the past year. The prevalence of any tested HPV type was 29.4% at the anal site and 11% at the penile site. One quarter of MSM were infected with any of the 9-valent vaccine HPV types. Anal HPV detection was associated with having three or more receptive anal sex partners in the past year (adjusted odds ratio (aOR)=2.92, 95% CI 1.29 to 6.61) and having older sex partners (aOR=2.51, 95% CI 1.07 to 5.90).ConclusionsOur data provide the base to calculate the reproductive rate for HPV transmission in a low-risk community sample and cost-effectiveness to include men in HPV vaccination policies. Adding evidence from a community sample adds comprehensiveness for future estimates of disease transmission and vaccine effectiveness.

Effects of human papillomavirus (HPV) and other potential risk factors on survival in patients with oropharyngeal cancer.

2011 ◽  
Vol 29 (15_suppl) ◽  
pp. 5577-5577 ◽  
Author(s):  
M. Knoedler ◽  
A. Zakarneh ◽  
U. Zimmermann ◽  
K. Woelke ◽  
O. Kaschke ◽  
...  
Keyword(s):  
Risk Factors ◽  
Human Papillomavirus ◽  
Potential Risk ◽  
Oropharyngeal Cancer ◽  
Potential Risk Factors

Prevalence of genital human papillomavirus DNA in a sample of senior school-aged women in the Australian Capital Territory

Sexual Health ◽  
2006 ◽  
Vol 3 (2) ◽  
pp. 91 ◽  
Author(s):  
Elissa J. O'Keefe ◽  
Anne Gardner ◽  
Marian J Currie ◽  
Suzanne Garland ◽  
Sepehr Tabrizi ◽  
...  
Keyword(s):  
Risk Factors ◽  
High School ◽  
Human Papillomavirus ◽  
Young Women ◽  
Hpv Infection ◽  
Senior High School ◽  
Sexually Active ◽  
Australian Capital Territory ◽  
Hpv Dna ◽  
Australian Capital

Background: A strong association between persistent infection with oncogenic types of human papillomavirus (HPV) and cervical cancer is well established. Small numbers of international studies examining adolescent HPV infection and the risk factors associated are published, but there is currently no evidence on the prevalence and risk factors for HPV in an Australian, sexually active female adolescent population. Methods: To provide prevalence and risk factors for HPV in a female sexually active, senior high school population in the Australian Capital Territory (ACT), a convenience sample of 161, 16–19-year-old females attending a senior high school was evaluated. The sample formed part of a larger sample recruited for a study of sexually transmitted infections and blood-borne viruses in senior high school students. A clinical record was used to collect information about sexual and other risk behaviours, while self-collected vaginal swabs were tested for HPV DNA detection and genotyping using polymerase chain reaction. Results: The prevalence of HPV DNA in this sample overall was 11.2%, with multiple genotypes in 38%. No statistically significant associations were found between HPV DNA and the number of male partners, age of coitarche, time since first sexually active, condom use, smoking or alcohol intake. Conclusions: This is the first Australian study that has examined the prevalence and risk factors for genital HPV in this demographic group. The prevalence of HPV infection is slightly lower than reported in similar age groups overseas and is lower than other Australian studies in older women and those attending sexual health centres. Of HPV-positive young women, high-risk genotypes were found in over half, with more than one-third of HPV existing as multiple genotypes. Large community-based prevalence studies are needed to guide the development of recommendations for the vaccination of young women against HPV and to support other health promotion initiatives.

8591 POSTER Effects of Human Papillomavirus (HPV) and Other Potential Risk Factors on Survival in Patients With Oropharyngeal Cancer

2011 ◽  
Vol 47 ◽  
pp. S570
Author(s):  
M. Knoedler ◽  
A. Zakarneh ◽  
U. Zimmermann ◽  
K. Woelke ◽  
O. Kaschke ◽  
...  
Keyword(s):  
Risk Factors ◽  
Human Papillomavirus ◽  
Potential Risk ◽  
Oropharyngeal Cancer ◽  
Potential Risk Factors

Risk contribution of sexual behavior and cigarette smoking to cervical neoplasia

2003 ◽  
Vol 13 (5) ◽  
pp. 617-625 ◽  
Author(s):  
C. H. Sierra-Torres ◽  
S. K. Tyring ◽  
W. W. Au
Keyword(s):  
Risk Factors ◽  
Sexual Behavior ◽  
Cigarette Smoking ◽  
Significant Risk ◽  
Significant Risk Factor ◽  
Hpv Infection ◽  
Cervical Neoplasia ◽  
Current Cigarette Smoking ◽  
The Us ◽  
Risk Contribution

Infection with high-risk human papillomavirus (HPV) is considered a “necessary cause” for cervical cancer (CC); however, only some HPV-infected women develop CC. We report on the differential risk contribution of sexual behavior and cigarette smoking to cervical neoplasia in the US and Venezuela. A total of 142 patients and 158 matched-controls were recruited from both countries using the same recruitment protocol, the same pathologists for case verification, and the same experimental procedures for analysis. HPV infection was significantly associated with CC for both populations as expected, but the Venezuelan controls were twice as likely to be infected with HPV as the US controls. Having >2 lifetime sexual partners (OR = 4.7, 95% CI = 1.7-13.1) and initiation of sexual activities before the age of 18 (OR = 4.7, 95% CI = 1.6-13.7) were significant risk factors in a multivariate model for CC in Venezuela. In contrast, current cigarette smoking was a significant risk factor only in the US (OR = 3.6, 95% CI = 1.7-7.7). The observed differences in risk factors support the need for additional studies in different geographic regions and the information can be used to develop country-specific CC prevention programs.

Risk Factors for High-Risk Human Papillomavirus Infection and Cofactors for High-Grade Cervical Disease in Peru

2011 ◽  
Vol 21 (9) ◽  
pp. 1654-1663 ◽  
Author(s):  
Maribel Almonte ◽  
Catterina Ferreccio ◽  
Miguel Gonzales ◽  
Jose Manuel Delgado ◽  
C. Hilary Buckley ◽  
...  
Keyword(s):  
Risk Factors ◽  
Human Papillomavirus ◽  
High Risk ◽  
Hpv Infection ◽  
High Grade ◽  
Papanicolaou Test ◽  
First Sexual Intercourse ◽  
Papillomavirus Infection ◽  
Cervical Disease ◽  
Potential Risk Factors

ObjectiveTo evaluate the association between potential risk factors for high-risk human papillomavirus (HR-HPV) infection and cofactors for cervical intraepithelial lesions grade 2 or worse (CIN2+) in women attending cervical screening in Amazonian Peru.Materials and MethodsParticipants completed a risk factor questionnaire before screening. High-risk human papillomavirus infection was determined by Hybrid Capture II. Logistic regression was used to evaluate associations between potential risk factors for HR-HPV infection and between cofactors and risk of CIN2+ among women with HR-HPV infection.ResultsScreening and questionnaires were completed by 5435 women aged 25 to 49 years. The prevalence of HR-HPV was 12.6% (95% confidence interval [CI], 11.8%–13.6%) and decreased by age. Early age at first sexual intercourse and several lifetime sexual partners increased the risk of having HR-HPV (age-adjusted odds ratio [AOR] of age at first sexual intercourse <18 vs ≥20, 1.5; 95% CI, 1.2–2.0; AOR of ≥5 lifetime sexual partners vs 1, 2.1; 95% CI, 1.4–3.2). Among women with HR-HPV infection, those with no schooling (AOR relative to 1–5 years of schooling, 3.2; 95% CI, 1.3–8.3) and those with parity ≥3 (AOR relative to parity <3, 2.6; 95% CI, 1.4–4.9) were at increased risk of CIN2+. The effect of parity was stronger for cancer (AOR of parity ≥3 vs <3, 8.3; 95% CI, 1.0–65.6). Further analysis showed that the association between parity and CIN2+ was restricted to women younger than 40. Most women (83%) had previously been screened. Sixty-four percent of CIN2+ cases detected in this study occurred in women who reported having had a Papanicolaou test in the previous 3 years. Only 4 of 20 cancers were detected in women never screened before. Having had a previous abnormal Papanicolaou test increased the risk of CIN2+ (OR, 16.1; 95% CI, 6.2–41.9).ConclusionAmong women with HR-HPV, high parity (in young women), no schooling, lack of good-quality screening and of adequate follow-up care are the main risk factors for high-grade cervical disease in Peru.

scholarly journals Prevalence and risk factors for oral human papillomavirus infection in Mexican HIV-infected men

10.21149/9834 ◽  
2018 ◽  
Vol 60 (6, nov-dic) ◽  
pp. 653
Author(s):  
Yuria Ablanedo-Terrazas ◽  
Karla Romero-Mora ◽  
María Gómez-Palacio ◽  
Claudia Alvarado-de la Barrera ◽  
Matilde Ruiz-Cruz ◽  
...  
Keyword(s):  
Risk Factors ◽  
Human Papillomavirus ◽  
Hpv Infection ◽  
Oral Infection ◽  
Behavioral Risk ◽  
Hiv Diagnosis ◽  
Hpv Dna ◽  
Papillomavirus Infection ◽  
Immunodeficiency Virus ◽  
Oral Hpv

Objective. To determine the prevalence and risk factors for oral high-risk human papillomavirus (HR-HPV) infection in human immunodeficiency virus (HIV)-infected men. Materials and methods. Consecutive male outpatients with HIV-infection were enrolled. Demographic and behavioral risk data were obtained. Anal swabs and oral rinses were tested for HR-HPV DNA. Oral, pharyngeal and video laryngoscopy examinations were performed for detection of lesions. Results. The prevalence of HR-HPV oral infection was 9.3% (subtypes other than HR HPV 16/18 predominated). The prevalence of anal HR-HPV infection was 75.7%. The risk factors for oral infection with HR-HPV were tonsillectomy (OR=13.12) and years from HIV diagnosis (OR=1.17). Conclusions. Tonsillectomy and years from HIV diagnosis were associated with oral HPV infection. No association was found between oral and anal HR-HPV infections. This is the first study reporting the prevalence and risk factors for oral HR-HPV infection in Mexican HIV-infected population.

Potential risk factors associated with the use of cidofovir to treat benign human papillomavirus-related disease

2009 ◽  
Vol 14 (7) ◽  
pp. 939-952 ◽  
Author(s):  
Adam J Donne ◽  
Lynne Hampson ◽  
Xiaotong T He ◽  
Philip JR Day ◽  
Fiona Salway ◽  
...  
Keyword(s):  
Risk Factors ◽  
Human Papillomavirus ◽  
Potential Risk ◽  
Factors Associated ◽  
Related Disease ◽  
Potential Risk Factors
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