Haemoperfusion: a Useful Therapy for a Severely Poisoned Patient?

1986 ◽  
Vol 5 (1) ◽  
pp. 11-14 ◽  
Author(s):  
M.E. De Broe ◽  
C. Bismuth ◽  
G. De Groot ◽  
A. Heath ◽  
S. Okonek ◽  
...  
Keyword(s):  
Clinical Efficacy ◽  
The Future ◽  
Practical Guidelines ◽  
Present Design ◽  
New Treatments ◽  
Wrong Interpretation

Although it is many years since a haemodialysis and haemoperfusion over uncoated and later coated charcoal columns have been used for the treatment of intoxicated patients, the clinical efficacy of these extracorporeal techniques in the treatment of severely poisoned patients remains a matter of debate. Some of the reasons for this controversy may be the indiscriminate use of haemoperfusion in any form of intoxication, the lack of well-controlled studies and the wrong interpretation of the high haemoperfusion clearance values sometimes obtained. Simple pharmacokinetic principles are applied to this type of treatment and some practical guidelines as to how and when haemoperfusion should be applied or presented are reviewed. The limited place of haemoperfusion in the treatment of severe poisoning, its further declining use in the future, at least in its present design, and some promising new treatments are emphasized.

From dominance to decline? The future of bibliographic discovery, access and delivery

2011 ◽  
Vol 36 (2) ◽  
pp. 33-36 ◽  
Author(s):  
Martin Flynn
Keyword(s):  
International Support ◽  
The Future ◽  
Practical Guidelines ◽  
Policies And Practices

It is undoubtedly an appropriate time to promote discussion of the strengths and weaknesses of traditional library cataloguing policies and practices, and to identify some potential improvements for the future. Four major recent reports on the future of library catalogues, produced by some of the key international players in the library world, have come up with remarkably similar conclusions and could provide libraries with some practical guidelines for improvement which enjoy a broad measure of international support in the library world.

scholarly journals Psychiatry in the future

2004 ◽  
Vol 28 (10) ◽  
pp. 355-356
Author(s):  
Trevor Turner ◽  
Trevor Turner
Keyword(s):  
National Health Service ◽  
Selective Serotonin Reuptake Inhibitors ◽  
Atypical Antipsychotics ◽  
Community Care ◽  
Social Attitudes ◽  
Full Time ◽  
Consultant Psychiatrist ◽  
The Future ◽  
New Treatments ◽  
New Buildings

As a general adult consultant psychiatrist who has worked full-time in the National Health Service (NHS) for 15 years, I have seen that things do change, but rarely in the ways expected or planned for. Having done the same job for six different reconfigurations of local services, I can confirm that reorganisation is largely irrelevant. However, new treatments (such as selective serotonin reuptake inhibitors and atypical antipsychotics) and new buildings, along with enthusiastic staff, can be seen as genuine advances. Changing social attitudes, in particular the rise of morbid individualism and an increasingly virulent, reactionary anti-science lobby, alongside sheer social overcrowding and pollution, do bring fears for the future. Community care has become a joke term rather than a watchword for acceptance of the stigmatised among ‘normal’ society. Three visions are possible: the dystopian, the normotopian and the utopian, looked at along the biopsychosocial spectrum.

Cultural Approach to Mitigate COVID-19's Impact

2021 ◽  
pp. 101-125
Author(s):  
Teresa Dieguez
Keyword(s):  
Sustainable Development ◽  
Best Practices ◽  
Critical Behaviour ◽  
Primary Data ◽  
Holistic Thinking ◽  
Cultural Approach ◽  
The World ◽  
The Future ◽  
Practical Guidelines ◽  
New Challenges

The world is shifting. The pandemic has changed paradigms, and people have reacted by trying to find solutions for problems. New challenges arise, and, more than ever, people must understand that the future depends on the way they face the present. The COVID-19 pandemic reinforced the need to collectively work in accordance to our realities. Co-creation, entrepreneurship, holistic thinking, and creativity are huge contributions that can make a difference. This chapter aims to explain and share best practices of Portugal and Brazil to mitigate COVID-19 impacts. Using primary data, a presentation is made between a varied set of measures and actions carried out by the two countries, similar in language but different in cultures and realities. The results could be practical guidelines for potential implementation elsewhere. The conclusion seems to point out that solutions require involvement for all stakeholders, with innovation and critical behaviour as means to pursue the path of sustainable development.

A New Approach

2000 ◽  
Author(s):  
Hans Tammemagi
Keyword(s):  
Sustainable Development ◽  
Surface Water ◽  
Waste Disposal ◽  
Future Generations ◽  
Minimal Risk ◽  
New Approach ◽  
The Future ◽  
Practical Guidelines ◽  
Basic Axiom

We need waste disposal methods that allow the human race to live on this planet in harmony with nature, preserving our resources and habitat and leaving a legacy for our children and grandchildren that does not deprive them of opportunities. These changes will not come easily; they will require resolve and foresight. Just as a mathematician develops the proof to a mathematical theorem, we must start from a basic axiom, and step by step, following a logical progression, we must build a practical framework for waste management. We started this task in chapter 2, where we derived three general principles from the axiom of sustainable development. Can we apply these general principles to develop practical guidelines—first, to overcome the shortcomings of existing landfills, and second, to find other, innovative disposal methods that will conform with sustainable development? Let us look at each of the three principles in turn. Human health and the environment must be protected, both now and in the future. This principle is fundamental and places important constraints on the siting and design of disposal facilities, and also on the form of the waste. In particular, the final four words, “and in the future,” are very important. This principle can be satisfied in two ways: by reducing the toxicity of the wastes so they pose minimal risk, or by containing wastes so that they cannot escape and cause harm. In some cases, the latter method includes controlled leakage at a rate that the environment can assimilate without long-term degradation. Wastes must be managed so that no burden is placed on future generations and they are not deprived of the opportunities we have had. In other words, our grandchildren should not have to spend their valuable resources to solve our waste problems, nor should they be denied resources because our generation has depleted them. Neither should their health and environment be placed at risk because of our actions. The main impacts of landfills on future generations are the requirement to provide ongoing guardianship and maintenance; the loss of valuable land; and impairment of groundwater, surface water, and the atmosphere.

scholarly journals Glycosylation of immune system proteins and its role in autoimmune diseases and cancer

2020 ◽  
Vol 18 (1) ◽  
pp. 32-37
Author(s):  
Anna Trzyna ◽  
◽  
Jacek Tabarkiewicz ◽  
Artur Mazur ◽  
◽  
...  
Keyword(s):  
Immune System ◽  
Autoimmune Diseases ◽  
Literature Search ◽  
Biological Significance ◽  
Cell Communication ◽  
Bibliographic Databases ◽  
Systematic Literature Search ◽  
Enzymatic Process ◽  
The Future ◽  
New Treatments

Introduction. Structural glycans have great biological significance and are involved in signaling and cell communication of the immune system. They are attached to proteins and lipids in an enzymatic process called glycosylation where glycosyltransferase and glycosidases bind sugar residues and lead to the formation of bioconjugates. Aim. In this paper we describe the importance of glycosylation in the immune system and its changes in diseases. Material and methods. This review was performed according to systematic literature search of major bibliographic databases. Results. Proper glycosylation ensures the functioning of the organism, however, defects in structural glycans of immune system changes their properties and can lead to disorders and further to autoimmune diseases. It has been also proven that glycosylation of autoimmune system is changed during cancer. In this paper we described types of structural glycans, significance of glycosylation of selected components of the immune system and its modifications in disorders. Conclusions. Knowledge about changes in the glycosylation in diseases is the key to understanding the processes of autoimmune diseases and may allow the development of new treatments in the future.

scholarly journals A Starter's Guide to Preclinical Teeth Arrangement: Simplified Clinometer

2012 ◽  
Vol 13 (2) ◽  
pp. 236-239
Author(s):  
K Srinivas Reddy ◽  
N Venugopal Rao ◽  
A Sudheer ◽  
C Sathya Nageswar Rao
Keyword(s):  
Clinical Significance ◽  
Undergraduate Students ◽  
Clinical Efficacy ◽  
Mean Value ◽  
The Future ◽  
Set Up ◽  
Artificial Teeth

ABSTRACT Arrangement of artificial teeth in a bilaterally symmetrical fashion with proper inclinations of teeth had been a challenging task for beginners. A variety of tools and guiding equipment have been developed to help students to learn teeth arrangement. Unfortunately, those tools were either costly or unsuitable for use with mean value articulators. This article attempts to introduce a simplified clinometer which can be attached to mean value articulator and can be used as a guide to arrange teeth in a bilaterally symmetrical manner by the undergraduates in both clinical and preclinical set-up. Clinical significance Training of the future dentists in sound esthetic principles in a preclinical environment, using this device, will increase the final clinical efficacy of their work. Aim The aim of this article is to provide a simple but effective device to undergraduate students to help them learn teeth arrangement easily and systematically. How to cite this article Rao NV, Sudheer A, Rao CSN Reddy KS. A Starter's Guide to Preclinical Teeth Arrangement: Simplified Clinometer. J Contemp Dent Pract 2012;13(2):236-239.

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